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The map label for this gene is ackA [H]

Identifier: 21674345

GI number: 21674345

Start: 1426329

End: 1427561

Strand: Reverse

Name: ackA [H]

Synonym: CT1525

Alternate gene names: 21674345

Gene position: 1427561-1426329 (Counterclockwise)

Preceding gene: 21674351

Following gene: 21674344

Centisome position: 66.25

GC content: 58.15

Gene sequence:

>1233_bases
TTGCCGTTTGTGCCTGTAATTTTTCTGAGGATTTTTGCCATGATGCCCAGGCCGGTGTGTACCATTCTTGCTCTCAATAC
CGGTTCGTCGAGTATCAAGTTTTCACTGTATGAGAGCGGGGATACCGAGGAGCTGCTCTTTTCCGGATCACTGACCCGGA
TCGGTTTGCCGGACGGACGCTTCTCCGTGACCGACCCCGAGGGTCGATTTATCGATTGTGAGCGGGTTGATGTTCCCGAT
CATGCCGCGGCTTGTCGCTACGTGTTTTCCTGGATCACGCAGCACGGCCCCGGAATGCCGGACGCTGTGGGCCATCGGGT
GGTGCATGGTGGACCCCGTCACACCACTCCCGAAAAGGTCACCTCTGAACTGCTTGACTCCATCGCCGAAATCGTTCCCT
ACGCCCCCGAACATCTGCCGCAGGCGCTGAACGCCATCCGCTACGCCGCATCCGAACTGCCGGGTGTGTTCCAGGTGGCC
TGCTTCGATACCGCATTCCACAGCACAATGCCGCCGCTGGCGAAGCTCTGTCCCATTCCTGAAGAGTACCGGAATCAGGG
GGTGCAGCGGTACGGGTTTCACGGTCTTTCCTACCAGTACATTCTCAGTCAACTGCAAGCCGAGGGGGATCCGTTTGCCC
GCAAGGGTCGCCTCATTCTCGCGCATCTCGGCCACGGAGCCAGCATGGCGGCGGTGCTCGACGGTCGGAGCGTCGAGACG
ACGATGGGCTTTTCGCCTGCGGGTGGCCTCGTGATGAGCACGCGCACGGGTGATCTCGATCCGGGCGTGGTGCTGTTTCT
GTTGCAGCAAGGGCATCTCGATTCAGATGGCTTGCGCGACATGGTGAACAAAAAGTCCGGCCTGCTTGGTGTCTCCGGCC
TGAGCGACGACATGCGCGACCTGCTTGACGCTGAAGCGGAGAACGAACAGGCGCGACTGGCCGGGGAGCTTTTCTGCTAC
AGCGCCCGCAAGCACATTGGCGCGCTCGTGGCGGTGCTCGGTGGCCTCGACATGATCGTCTTCACCGGCGGCATTGGCCT
TTATTCGCCAGATGTTCGCGAGCGAATCTGTTCAGGCCTCGAATTTCTTGGCGTCCAGGTTGATCATGAAAAGAATCTGA
ATCATTCCGGAATTATTTCGACAGATACCAGCCGGGTTGTCGTCAAAGTTATTGAAACCAACGAAGAGGTGACGATTGTC
AGAGAGACAAGACGTGTGCTCGAAAATGGTTGA

Upstream 100 bases:

>100_bases
CGTGCCCCCTCCGAGTTTTCAGGAACGTAACGACTTACCGGCTTGGTTAGTGTTGTCTATCATGTATCTTGATCTTACTT
TTTGGAGCTGACGGTGATGG

Downstream 100 bases:

>100_bases
TGTGATGCCAATATGGTGTGGTTACCGGTTTGGCATTGAATGACGAAAGGAGGGCGGCACCGGTTCACTGGTGCCACCCT
CTCGTTTAACGTGATGCACT

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase [H]

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MPFVPVIFLRIFAMMPRPVCTILALNTGSSSIKFSLYESGDTEELLFSGSLTRIGLPDGRFSVTDPEGRFIDCERVDVPD
HAAACRYVFSWITQHGPGMPDAVGHRVVHGGPRHTTPEKVTSELLDSIAEIVPYAPEHLPQALNAIRYAASELPGVFQVA
CFDTAFHSTMPPLAKLCPIPEEYRNQGVQRYGFHGLSYQYILSQLQAEGDPFARKGRLILAHLGHGASMAAVLDGRSVET
TMGFSPAGGLVMSTRTGDLDPGVVLFLLQQGHLDSDGLRDMVNKKSGLLGVSGLSDDMRDLLDAEAENEQARLAGELFCY
SARKHIGALVAVLGGLDMIVFTGGIGLYSPDVRERICSGLEFLGVQVDHEKNLNHSGIISTDTSRVVVKVIETNEEVTIV
RETRRVLENG

Sequences:

>Translated_410_residues
MPFVPVIFLRIFAMMPRPVCTILALNTGSSSIKFSLYESGDTEELLFSGSLTRIGLPDGRFSVTDPEGRFIDCERVDVPD
HAAACRYVFSWITQHGPGMPDAVGHRVVHGGPRHTTPEKVTSELLDSIAEIVPYAPEHLPQALNAIRYAASELPGVFQVA
CFDTAFHSTMPPLAKLCPIPEEYRNQGVQRYGFHGLSYQYILSQLQAEGDPFARKGRLILAHLGHGASMAAVLDGRSVET
TMGFSPAGGLVMSTRTGDLDPGVVLFLLQQGHLDSDGLRDMVNKKSGLLGVSGLSDDMRDLLDAEAENEQARLAGELFCY
SARKHIGALVAVLGGLDMIVFTGGIGLYSPDVRERICSGLEFLGVQVDHEKNLNHSGIISTDTSRVVVKVIETNEEVTIV
RETRRVLENG
>Mature_409_residues
PFVPVIFLRIFAMMPRPVCTILALNTGSSSIKFSLYESGDTEELLFSGSLTRIGLPDGRFSVTDPEGRFIDCERVDVPDH
AAACRYVFSWITQHGPGMPDAVGHRVVHGGPRHTTPEKVTSELLDSIAEIVPYAPEHLPQALNAIRYAASELPGVFQVAC
FDTAFHSTMPPLAKLCPIPEEYRNQGVQRYGFHGLSYQYILSQLQAEGDPFARKGRLILAHLGHGASMAAVLDGRSVETT
MGFSPAGGLVMSTRTGDLDPGVVLFLLQQGHLDSDGLRDMVNKKSGLLGVSGLSDDMRDLLDAEAENEQARLAGELFCYS
ARKHIGALVAVLGGLDMIVFTGGIGLYSPDVRERICSGLEFLGVQVDHEKNLNHSGIISTDTSRVVVKVIETNEEVTIVR
ETRRVLENG

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family [H]

Homologues:

Organism=Escherichia coli, GI145693184, Length=391, Percent_Identity=38.8746803069054, Blast_Score=234, Evalue=6e-63,
Organism=Escherichia coli, GI1788633, Length=396, Percent_Identity=35.6060606060606, Blast_Score=230, Evalue=1e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000890
- InterPro:   IPR004372 [H]

Pfam domain/function: PF00871 Acetate_kinase [H]

EC number: =2.7.2.1 [H]

Molecular weight: Translated: 44576; Mature: 44445

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS01075 ACETATE_KINASE_1 ; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFVPVIFLRIFAMMPRPVCTILALNTGSSSIKFSLYESGDTEELLFSGSLTRIGLPDGR
CCCHHHHHHHHHHHCCCCEEEEEEEECCCCCEEEEEECCCCCHHEEECCCEEEECCCCCC
FSVTDPEGRFIDCERVDVPDHAAACRYVFSWITQHGPGMPDAVGHRVVHGGPRHTTPEKV
EEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCHHHCCHHCCCCCCCCCHHHH
TSELLDSIAEIVPYAPEHLPQALNAIRYAASELPGVFQVACFDTAFHSTMPPLAKLCPIP
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCHHHHCCCC
EEYRNQGVQRYGFHGLSYQYILSQLQAEGDPFARKGRLILAHLGHGASMAAVLDGRSVET
HHHHHCCCHHHCCCCCHHHHHHHHHHCCCCCCHHCCCEEEEECCCCCCEEEEECCCCEEE
TMGFSPAGGLVMSTRTGDLDPGVVLFLLQQGHLDSDGLRDMVNKKSGLLGVSGLSDDMRD
ECCCCCCCCEEEECCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCEEECCCCHHHHH
LLDAEAENEQARLAGELFCYSARKHIGALVAVLGGLDMIVFTGGIGLYSPDVRERICSGL
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHCCH
EFLGVQVDHEKNLNHSGIISTDTSRVVVKVIETNEEVTIVRETRRVLENG
HHEEEEECCCCCCCCCCEEECCCCEEEEEEEECCCCEEEHHHHHHHHHCC
>Mature Secondary Structure 
PFVPVIFLRIFAMMPRPVCTILALNTGSSSIKFSLYESGDTEELLFSGSLTRIGLPDGR
CCHHHHHHHHHHHCCCCEEEEEEEECCCCCEEEEEECCCCCHHEEECCCEEEECCCCCC
FSVTDPEGRFIDCERVDVPDHAAACRYVFSWITQHGPGMPDAVGHRVVHGGPRHTTPEKV
EEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCHHHCCHHCCCCCCCCCHHHH
TSELLDSIAEIVPYAPEHLPQALNAIRYAASELPGVFQVACFDTAFHSTMPPLAKLCPIP
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCHHHHCCCC
EEYRNQGVQRYGFHGLSYQYILSQLQAEGDPFARKGRLILAHLGHGASMAAVLDGRSVET
HHHHHCCCHHHCCCCCHHHHHHHHHHCCCCCCHHCCCEEEEECCCCCCEEEEECCCCEEE
TMGFSPAGGLVMSTRTGDLDPGVVLFLLQQGHLDSDGLRDMVNKKSGLLGVSGLSDDMRD
ECCCCCCCCEEEECCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCEEECCCCHHHHH
LLDAEAENEQARLAGELFCYSARKHIGALVAVLGGLDMIVFTGGIGLYSPDVRERICSGL
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHCCH
EFLGVQVDHEKNLNHSGIISTDTSRVVVKVIETNEEVTIVRETRRVLENG
HHEEEEECCCCCCCCCCEEECCCCEEEEEEEECCCCEEEHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA