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The map label for this gene is aspC-2 [H]

Identifier: 21674203

GI number: 21674203

Start: 1295846

End: 1297006

Strand: Reverse

Name: aspC-2 [H]

Synonym: CT1381

Alternate gene names: 21674203

Gene position: 1297006-1295846 (Counterclockwise)

Preceding gene: 21674204

Following gene: 21674202

Centisome position: 60.19

GC content: 62.27

Gene sequence:

>1161_bases
ATGGGTTTGAGTCTTGGCGAACGTTGCGGGCTGGTCATGCAGTCCGATATTCGCGCCATGTCGATCGAGTGCGCCCGCAT
GGGTGGGATCAATCTTTCGCAGGGTGTTTGCGATACGCCGGTGCCGCCGGTGGTGTTGCAAGGGGCCGCCGATGCGGTGA
TGCAGGGGGCGAACATCTATACGCATCACACTGGCATCCGCGAACTGCGCGAAGCGATTGTCGCCAAGCAGCGCCGTTTC
ACCGGCGTGGCATTCGACGCCGAGCGCGAGGTGGTCGTCTCCGCCGGGGCGACGGGCGCGATGTACTGCGCGTTTCAGGC
GCTGCTCAATCGCGGCGACGAGGTGATCGTGTTCGAGCCTTTTTACGGCTACCACGTCTCGACGCTTCGGGCGGTCGAGG
CTGTGCCGTTGTTCGTGCCGCTCGATCCGTCGGACGGCTGGTCGTTCCGCGTCGAAGCCCTCGAAGCGGCAGTGACACCG
AAGACCAAAGCGCTGCTCATCAATACGCCCGCCAATCCCTCCGGCAAGGTCTTTTCGTGCGACGAACTGGCGCTGCTGGC
GGAGTTTGCCATCCGCCACGACCTGTTTGTTTTCACTGACGAGATGTACGAGCACTTCGTGTTCGGCGGCCTTTCGCACG
TTTCGATGGCCTCGATGCCCGGCATGAGGGAGCGTACGATCACTATCTCCGGTCTCTCGAAGACGTTCAGCGTTACCGGC
TGGCGTATTGGCTATGCGCTATGCGACCCGCGCTGGGCTGCCTCCATCGGCTATTTCAACGATCTTTTCTATGTCTGCGC
GGCATCGCCGCTTCAGGTGGGTGTTACGGCGGGGCTTCGCTTGCTTGGCGACGACTACTATCATGGTCTGGCAGCCGAAT
ATGAGGTCAGGCGTGATCTTTTCTGCGCGGCGCTCGCCGAGGCTGGACTCGAACCGCATGTGCCGCAGGGCGCGTACTAC
GTGCTTGCCGGCACGGAGCGCTTACCCGGCGCGACGGCGCGGGAAAAGGCGATGCACATTCTGCGCGAAACCGGTGTCGC
TTCGGTGCCCGGCTCGGCATTCTACCACGACGGCGGCGGCGAGAATCTCGTCCGCTTCTGTTTCGCCAAGGAAAGCCATG
TGCTCGAAGCGGCCTGCGAGAAACTGCTGAAGCTCAGGTAA

Upstream 100 bases:

>100_bases
CCGCCGGGGGCTTTTTGTTGGCAACAGGTTTATCGAGCATCCGGTTTGCCGGTGCTCTTTGAATGATCATGATTGCCATA
ACCTTTTTCTGGAAGTAACC

Downstream 100 bases:

>100_bases
ATTCAACAATTTCGCGTAATCATCCATCAGAATGGGGGCTTGAAAATAATGGCTGATACAGCGCTACTCCAGAGCATCGT
CAAATTGACAAGGCCGCTTT

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 386; Mature: 385

Protein sequence:

>386_residues
MGLSLGERCGLVMQSDIRAMSIECARMGGINLSQGVCDTPVPPVVLQGAADAVMQGANIYTHHTGIRELREAIVAKQRRF
TGVAFDAEREVVVSAGATGAMYCAFQALLNRGDEVIVFEPFYGYHVSTLRAVEAVPLFVPLDPSDGWSFRVEALEAAVTP
KTKALLINTPANPSGKVFSCDELALLAEFAIRHDLFVFTDEMYEHFVFGGLSHVSMASMPGMRERTITISGLSKTFSVTG
WRIGYALCDPRWAASIGYFNDLFYVCAASPLQVGVTAGLRLLGDDYYHGLAAEYEVRRDLFCAALAEAGLEPHVPQGAYY
VLAGTERLPGATAREKAMHILRETGVASVPGSAFYHDGGGENLVRFCFAKESHVLEAACEKLLKLR

Sequences:

>Translated_386_residues
MGLSLGERCGLVMQSDIRAMSIECARMGGINLSQGVCDTPVPPVVLQGAADAVMQGANIYTHHTGIRELREAIVAKQRRF
TGVAFDAEREVVVSAGATGAMYCAFQALLNRGDEVIVFEPFYGYHVSTLRAVEAVPLFVPLDPSDGWSFRVEALEAAVTP
KTKALLINTPANPSGKVFSCDELALLAEFAIRHDLFVFTDEMYEHFVFGGLSHVSMASMPGMRERTITISGLSKTFSVTG
WRIGYALCDPRWAASIGYFNDLFYVCAASPLQVGVTAGLRLLGDDYYHGLAAEYEVRRDLFCAALAEAGLEPHVPQGAYY
VLAGTERLPGATAREKAMHILRETGVASVPGSAFYHDGGGENLVRFCFAKESHVLEAACEKLLKLR
>Mature_385_residues
GLSLGERCGLVMQSDIRAMSIECARMGGINLSQGVCDTPVPPVVLQGAADAVMQGANIYTHHTGIRELREAIVAKQRRFT
GVAFDAEREVVVSAGATGAMYCAFQALLNRGDEVIVFEPFYGYHVSTLRAVEAVPLFVPLDPSDGWSFRVEALEAAVTPK
TKALLINTPANPSGKVFSCDELALLAEFAIRHDLFVFTDEMYEHFVFGGLSHVSMASMPGMRERTITISGLSKTFSVTGW
RIGYALCDPRWAASIGYFNDLFYVCAASPLQVGVTAGLRLLGDDYYHGLAAEYEVRRDLFCAALAEAGLEPHVPQGAYYV
LAGTERLPGATAREKAMHILRETGVASVPGSAFYHDGGGENLVRFCFAKESHVLEAACEKLLKLR

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=384, Percent_Identity=32.8125, Blast_Score=209, Evalue=3e-54,
Organism=Homo sapiens, GI56713256, Length=384, Percent_Identity=32.8125, Blast_Score=209, Evalue=4e-54,
Organism=Homo sapiens, GI95147551, Length=389, Percent_Identity=33.1619537275064, Blast_Score=201, Evalue=7e-52,
Organism=Homo sapiens, GI169881279, Length=389, Percent_Identity=33.1619537275064, Blast_Score=201, Evalue=7e-52,
Organism=Homo sapiens, GI169881281, Length=302, Percent_Identity=32.7814569536424, Blast_Score=158, Evalue=8e-39,
Organism=Homo sapiens, GI4507369, Length=356, Percent_Identity=24.7191011235955, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI149944424, Length=173, Percent_Identity=32.3699421965318, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1786816, Length=368, Percent_Identity=34.5108695652174, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI1788722, Length=357, Percent_Identity=28.2913165266106, Blast_Score=118, Evalue=6e-28,
Organism=Escherichia coli, GI1788627, Length=253, Percent_Identity=28.8537549407115, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1787909, Length=129, Percent_Identity=29.4573643410853, Blast_Score=68, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI71994472, Length=395, Percent_Identity=31.3924050632911, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI71994476, Length=396, Percent_Identity=31.3131313131313, Blast_Score=189, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI17567369, Length=392, Percent_Identity=28.0612244897959, Blast_Score=161, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI17567663, Length=297, Percent_Identity=26.2626262626263, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6322401, Length=387, Percent_Identity=29.7157622739018, Blast_Score=170, Evalue=3e-43,
Organism=Drosophila melanogaster, GI28573069, Length=387, Percent_Identity=31.266149870801, Blast_Score=195, Evalue=5e-50,
Organism=Drosophila melanogaster, GI24646114, Length=387, Percent_Identity=31.266149870801, Blast_Score=195, Evalue=5e-50,
Organism=Drosophila melanogaster, GI28573067, Length=387, Percent_Identity=31.266149870801, Blast_Score=195, Evalue=5e-50,
Organism=Drosophila melanogaster, GI28573065, Length=387, Percent_Identity=31.266149870801, Blast_Score=195, Evalue=5e-50,
Organism=Drosophila melanogaster, GI18859735, Length=303, Percent_Identity=28.7128712871287, Blast_Score=115, Evalue=6e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 41861; Mature: 41730

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLSLGERCGLVMQSDIRAMSIECARMGGINLSQGVCDTPVPPVVLQGAADAVMQGANIY
CCCCCCCCCCEEECCCCHHEEEEHHHCCCCCCCCCCCCCCCCCEEECCCHHHHHCCCCEE
THHTGIRELREAIVAKQRRFTGVAFDAEREVVVSAGATGAMYCAFQALLNRGDEVIVFEP
EECCCHHHHHHHHHHHHHHCCEEEECCCCEEEEECCCCHHHHHHHHHHHCCCCEEEEECC
FYGYHVSTLRAVEAVPLFVPLDPSDGWSFRVEALEAAVTPKTKALLINTPANPSGKVFSC
CCCCHHHHHHHHHHEEEEEECCCCCCCEEEEEEHHHHCCCCCEEEEEECCCCCCCCEEEH
DELALLAEFAIRHDLFVFTDEMYEHFVFGGLSHVSMASMPGMRERTITISGLSKTFSVTG
HHHHHHHHHHHHHHHEEEEHHHHHHHHHCCHHHHHHHCCCCCCEEEEEEECCCCEEEECC
WRIGYALCDPRWAASIGYFNDLFYVCAASPLQVGVTAGLRLLGDDYYHGLAAEYEVRRDL
EEEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHCCHHHCCCHHHHHHHHHH
FCAALAEAGLEPHVPQGAYYVLAGTERLPGATAREKAMHILRETGVASVPGSAFYHDGGG
HHHHHHHCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEECCCC
ENLVRFCFAKESHVLEAACEKLLKLR
CHHHHHHHCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
GLSLGERCGLVMQSDIRAMSIECARMGGINLSQGVCDTPVPPVVLQGAADAVMQGANIY
CCCCCCCCCEEECCCCHHEEEEHHHCCCCCCCCCCCCCCCCCEEECCCHHHHHCCCCEE
THHTGIRELREAIVAKQRRFTGVAFDAEREVVVSAGATGAMYCAFQALLNRGDEVIVFEP
EECCCHHHHHHHHHHHHHHCCEEEECCCCEEEEECCCCHHHHHHHHHHHCCCCEEEEECC
FYGYHVSTLRAVEAVPLFVPLDPSDGWSFRVEALEAAVTPKTKALLINTPANPSGKVFSC
CCCCHHHHHHHHHHEEEEEECCCCCCCEEEEEEHHHHCCCCCEEEEEECCCCCCCCEEEH
DELALLAEFAIRHDLFVFTDEMYEHFVFGGLSHVSMASMPGMRERTITISGLSKTFSVTG
HHHHHHHHHHHHHHHEEEEHHHHHHHHHCCHHHHHHHCCCCCCEEEEEEECCCCEEEECC
WRIGYALCDPRWAASIGYFNDLFYVCAASPLQVGVTAGLRLLGDDYYHGLAAEYEVRRDL
EEEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHCCHHHCCCHHHHHHHHHH
FCAALAEAGLEPHVPQGAYYVLAGTERLPGATAREKAMHILRETGVASVPGSAFYHDGGG
HHHHHHHCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEECCCC
ENLVRFCFAKESHVLEAACEKLLKLR
CHHHHHHHCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]