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The map label for this gene is murB [H]

Identifier: 21674053

GI number: 21674053

Start: 1151355

End: 1152947

Strand: Reverse

Name: murB [H]

Synonym: CT1228

Alternate gene names: 21674053

Gene position: 1152947-1151355 (Counterclockwise)

Preceding gene: 21674054

Following gene: 21674052

Centisome position: 53.5

GC content: 62.4

Gene sequence:

>1593_bases
ATGACCGAGCCGATTTTTCCCTGTCCTTTCGATGAGCGGATGCCGCTGTCAACCGTCGGTTACTACGGTATCGGCGGGGA
GGCTCGCTGGATCGTTCATCCCCGGAGTGTTGGGGAGCTCGCTTTGGTGCTTGACCGCTGCCGTCAGCTTGGCCTGCCGG
TCATTATCGCTGGAAAGGGGAGCAACATGCTCTTTTCGGATGAGGAATTCCCCGGCGTGGTCATCGTTCTTGATGCGATG
AATCGCATGTTTCAGGTCTCCGACGAGCTGTTTTTCTGCGAGGCAGGGGTTGAGAACACCGACGCGGCTATCGTGCTTCA
GGAGGCGGGCCGGTGTGGCGGGGAGTGGCTTTACCGCCTGCCGGGAACCATCGGCGCGACGGTGCGCATGAACGGGCGCT
GCTACGGACGCGAGATTTCCGCCGTGGCCAGAAGCGTCGTGACGGTTGGGCTGGATGGCGCGGTTCGCTGGCGTCGTGCT
GACGAGGTGTTCCTCGGCTACAAGGAGACCCGCCTGATGCAAAGCCCGGAGATCGTGGTTGGCGCGATGCTTGAATTTGC
TGAGCACGATGAGCCCGAAGCTATCGGCAAGCGGATGCAGGAGTACGGCGACGACCGCGACGCGAAGCACCAGTTCGATT
TTCCAAGCTGCGGTTCTACGTTCAAAAACAGCTACGATGCGGGCCGCCCGAGCGGGCAGATTTTCGACGCTCTCGGCTTT
CGGGGTCGCCGAGAAGGCGGGGCGCAGGTGAGCGACCACCATGCCAACTTCATTTTCAACACTGGCGGGGCGAAGGCTGC
CGATGTGCTGAATCTTTGTGCCGCCATGCGCACCGAAGCGCGCGAGAAGTTGGGTGCGACGCTGGAGCTCGAACTCCAGT
GCGCCGGACTGTTCCAAACAGCGCTGCTCGACGCCTGTGGCATCGCCTCGACGCCCGAGCCTTCGCGCCCCGGTTATGGC
TGGACAGGCCTGTTGCCCTTCCCGGATGCTTGCGATGACGCCTTTCCGCGCGTCTTGCTGCAAGGTGAAGCGCTCGACTA
CTTCTGCCGTGACGCCGTGTTTCCGGCTGGCATCGCCGTCGAAGTCGGCCAGCTCATTCCGCTCGACGAGGCGCGAAAAG
CGCCGGATCGGCCCTTCATCCGCTGGACGACGCGCGACGAATCGGGTGTGGCGTTTTCATTGCATCCCGATGCTCCGGTG
GGAGCGTTCGTTGATCGTTTGTGGGAGCACAACGTCTCCGAGCTGTTCATCGGCCAAGGCGGCGGAAGCGGGCAGTATCT
CGAATTCGAGGTGACGCCGGAAGGCCACTGGCTCGCCATCCGCTTCGACGCCCCACGCCAGCGAACCGCCGGGCACGAAA
TTCCGTCGGAGGAACTCTGGCGCAGCCAGGCAACGCCCTTCGCCAGCGAAAAAGGCTTCGGCATAGAGCTTTCATACGCC
CTGCTGGAGCCGTTTATCCACGACGATACGCTCCGATTGCAATGCGCCGTCAGCCTCGGAGATGGGCGTTACGGACTATT
TCCATGGTGGCGTGGAGAGGGGGCGCCGGATTTCCACCAGCCGGAGAGGTATTGCGTAGTGCGGTTGGGGTGA

Upstream 100 bases:

>100_bases
CTCTTTTTCGTGCTTTTTTTCAGGGATAGCGCCATGTCGCCTATATTTCAACCTTTTGACAAGAGCACTGACTGAAACAA
GCCTCTCAGATCATTTATTT

Downstream 100 bases:

>100_bases
AGATAATAATAATCTTCAATGTTCAACTTTGTTGATAAAATGTCTTTGCTTTCACACTACACCACGGGTTCTTCTCAGAT
TACCGTGGGTAAATGGTGAA

Product: UDP-N-acetylenolpyruvoylglucosamine reductase, putative

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 530; Mature: 529

Protein sequence:

>530_residues
MTEPIFPCPFDERMPLSTVGYYGIGGEARWIVHPRSVGELALVLDRCRQLGLPVIIAGKGSNMLFSDEEFPGVVIVLDAM
NRMFQVSDELFFCEAGVENTDAAIVLQEAGRCGGEWLYRLPGTIGATVRMNGRCYGREISAVARSVVTVGLDGAVRWRRA
DEVFLGYKETRLMQSPEIVVGAMLEFAEHDEPEAIGKRMQEYGDDRDAKHQFDFPSCGSTFKNSYDAGRPSGQIFDALGF
RGRREGGAQVSDHHANFIFNTGGAKAADVLNLCAAMRTEAREKLGATLELELQCAGLFQTALLDACGIASTPEPSRPGYG
WTGLLPFPDACDDAFPRVLLQGEALDYFCRDAVFPAGIAVEVGQLIPLDEARKAPDRPFIRWTTRDESGVAFSLHPDAPV
GAFVDRLWEHNVSELFIGQGGGSGQYLEFEVTPEGHWLAIRFDAPRQRTAGHEIPSEELWRSQATPFASEKGFGIELSYA
LLEPFIHDDTLRLQCAVSLGDGRYGLFPWWRGEGAPDFHQPERYCVVRLG

Sequences:

>Translated_530_residues
MTEPIFPCPFDERMPLSTVGYYGIGGEARWIVHPRSVGELALVLDRCRQLGLPVIIAGKGSNMLFSDEEFPGVVIVLDAM
NRMFQVSDELFFCEAGVENTDAAIVLQEAGRCGGEWLYRLPGTIGATVRMNGRCYGREISAVARSVVTVGLDGAVRWRRA
DEVFLGYKETRLMQSPEIVVGAMLEFAEHDEPEAIGKRMQEYGDDRDAKHQFDFPSCGSTFKNSYDAGRPSGQIFDALGF
RGRREGGAQVSDHHANFIFNTGGAKAADVLNLCAAMRTEAREKLGATLELELQCAGLFQTALLDACGIASTPEPSRPGYG
WTGLLPFPDACDDAFPRVLLQGEALDYFCRDAVFPAGIAVEVGQLIPLDEARKAPDRPFIRWTTRDESGVAFSLHPDAPV
GAFVDRLWEHNVSELFIGQGGGSGQYLEFEVTPEGHWLAIRFDAPRQRTAGHEIPSEELWRSQATPFASEKGFGIELSYA
LLEPFIHDDTLRLQCAVSLGDGRYGLFPWWRGEGAPDFHQPERYCVVRLG
>Mature_529_residues
TEPIFPCPFDERMPLSTVGYYGIGGEARWIVHPRSVGELALVLDRCRQLGLPVIIAGKGSNMLFSDEEFPGVVIVLDAMN
RMFQVSDELFFCEAGVENTDAAIVLQEAGRCGGEWLYRLPGTIGATVRMNGRCYGREISAVARSVVTVGLDGAVRWRRAD
EVFLGYKETRLMQSPEIVVGAMLEFAEHDEPEAIGKRMQEYGDDRDAKHQFDFPSCGSTFKNSYDAGRPSGQIFDALGFR
GRREGGAQVSDHHANFIFNTGGAKAADVLNLCAAMRTEAREKLGATLELELQCAGLFQTALLDACGIASTPEPSRPGYGW
TGLLPFPDACDDAFPRVLLQGEALDYFCRDAVFPAGIAVEVGQLIPLDEARKAPDRPFIRWTTRDESGVAFSLHPDAPVG
AFVDRLWEHNVSELFIGQGGGSGQYLEFEVTPEGHWLAIRFDAPRQRTAGHEIPSEELWRSQATPFASEKGFGIELSYAL
LEPFIHDDTLRLQCAVSLGDGRYGLFPWWRGEGAPDFHQPERYCVVRLG

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 58446; Mature: 58314

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEPIFPCPFDERMPLSTVGYYGIGGEARWIVHPRSVGELALVLDRCRQLGLPVIIAGKG
CCCCCCCCCCCCCCCCHHCCEEECCCCEEEEECCCCHHHHHHHHHHHHHCCCCEEEEECC
SNMLFSDEEFPGVVIVLDAMNRMFQVSDELFFCEAGVENTDAAIVLQEAGRCGGEWLYRL
CCCEECCCCCCCEEEEHHHHHHHHHHCCCEEEEECCCCCCCEEEEEECCCCCCCHHHEEC
PGTIGATVRMNGRCYGREISAVARSVVTVGLDGAVRWRRADEVFLGYKETRLMQSPEIVV
CCCEEEEEEECCEEECHHHHHHHHHHHEECCCCCEEEECCCCEEECCHHHHHCCCCCHHH
GAMLEFAEHDEPEAIGKRMQEYGDDRDAKHQFDFPSCGSTFKNSYDAGRPSGQIFDALGF
HHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCHHHHHHCC
RGRREGGAQVSDHHANFIFNTGGAKAADVLNLCAAMRTEAREKLGATLELELQCAGLFQT
CCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEHHHHHH
ALLDACGIASTPEPSRPGYGWTGLLPFPDACDDAFPRVLLQGEALDYFCRDAVFPAGIAV
HHHHHCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHEECCCHHHHHHHHCCCCCCCEE
EVGQLIPLDEARKAPDRPFIRWTTRDESGVAFSLHPDAPVGAFVDRLWEHNVSELFIGQG
ECCCCCCCHHHHCCCCCCEEEEECCCCCCCEEEECCCCCHHHHHHHHHHCCCCEEEEECC
GGSGQYLEFEVTPEGHWLAIRFDAPRQRTAGHEIPSEELWRSQATPFASEKGFGIELSYA
CCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCEEEEHH
LLEPFIHDDTLRLQCAVSLGDGRYGLFPWWRGEGAPDFHQPERYCVVRLG
HHHHHHCCCCEEEEEEEEECCCCCCCCEEECCCCCCCCCCCCEEEEEEEC
>Mature Secondary Structure 
TEPIFPCPFDERMPLSTVGYYGIGGEARWIVHPRSVGELALVLDRCRQLGLPVIIAGKG
CCCCCCCCCCCCCCCHHCCEEECCCCEEEEECCCCHHHHHHHHHHHHHCCCCEEEEECC
SNMLFSDEEFPGVVIVLDAMNRMFQVSDELFFCEAGVENTDAAIVLQEAGRCGGEWLYRL
CCCEECCCCCCCEEEEHHHHHHHHHHCCCEEEEECCCCCCCEEEEEECCCCCCCHHHEEC
PGTIGATVRMNGRCYGREISAVARSVVTVGLDGAVRWRRADEVFLGYKETRLMQSPEIVV
CCCEEEEEEECCEEECHHHHHHHHHHHEECCCCCEEEECCCCEEECCHHHHHCCCCCHHH
GAMLEFAEHDEPEAIGKRMQEYGDDRDAKHQFDFPSCGSTFKNSYDAGRPSGQIFDALGF
HHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCHHHHHHCC
RGRREGGAQVSDHHANFIFNTGGAKAADVLNLCAAMRTEAREKLGATLELELQCAGLFQT
CCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEHHHHHH
ALLDACGIASTPEPSRPGYGWTGLLPFPDACDDAFPRVLLQGEALDYFCRDAVFPAGIAV
HHHHHCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHEECCCHHHHHHHHCCCCCCCEE
EVGQLIPLDEARKAPDRPFIRWTTRDESGVAFSLHPDAPVGAFVDRLWEHNVSELFIGQG
ECCCCCCCHHHHCCCCCCEEEEECCCCCCCEEEECCCCCHHHHHHHHHHCCCCEEEEECC
GGSGQYLEFEVTPEGHWLAIRFDAPRQRTAGHEIPSEELWRSQATPFASEKGFGIELSYA
CCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCEEEEHH
LLEPFIHDDTLRLQCAVSLGDGRYGLFPWWRGEGAPDFHQPERYCVVRLG
HHHHHHCCCCEEEEEEEEECCCCCCCCEEECCCCCCCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA