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The map label for this gene is lolC [H]

Identifier: 21673928

GI number: 21673928

Start: 1037206

End: 1038456

Strand: Reverse

Name: lolC [H]

Synonym: CT1102

Alternate gene names: 21673928

Gene position: 1038456-1037206 (Counterclockwise)

Preceding gene: 21673929

Following gene: 21673924

Centisome position: 48.19

GC content: 59.87

Gene sequence:

>1251_bases
ATGAAAGCAGGTATCTGGATAGCCGGGCGTTACAGCTTCGCGCGCAAGCGCTTCCGGGTAATCAATATTATTTCGGGCAT
CAGTCTCGCGGGGATCGTCGTCGGCGTCTCGACGCTGCTCGTTGTGATGAGCGTGCTGAACGGCTTCCAGAAGCTGGCCC
GTGACCTCTTCGTGACCGTTGAAGGTCCGGTTCAGATCGTGCCCGCGCAGGGGCGCTCGCTGGTAGTGAGCGACTCTCTG
CTTGCCGCCATCGCCAGGCTCGATGGCGTCGAAACGGCGCACCCCTTCGTCGAGGGGCAGGCGATTATTACTGCGTCGGG
CAAAAGCGAGCTGATCATGGTGCGCGGTTTGACCGCCGAGGCGCAGCGCTCTCTGATGCAAACGACCTCCACCACGCAGC
CCTATTTCTCCACAGACGGAATCTCGGCAGGTAACCTGCTTGCTGAAAGGCTACGGCTTTACCCTGATGAACCGGTGCGG
CTCTTCAGCCCGGAGCTGATTTCAGCTGGCCTGCAAGCCCTTTCGCAACCGGAGCTGATGCCCGCGCTTTCGATGAGCGA
CGTGCGAGTCCAGAGCAGCTTTTCGCTGCAAAAGCTGTTCGACGACCGCTACGTGCTCGCGCCGGTTGAAATGGCCCAGA
ACATCCTGCTTTTCGGTCGTGGGCGCTACTCTGGCATCGACATCAGGGGGAAGTCAGGGGTGAGCGACGAAACGCTCGAA
GCTCGACTTCGCGAATGGATTTCGGCAACCCATCGGGAAAAAACGTTGCGTGTGGTAACGCTGCGGGAGCGGCACCGCGA
CATGTTTGCCGTGATGCAGCTTGAAAAGTGGGCCAGCTTCGCCGTGCTGATGCTGGTGATTCTGGTGGCTCTTCTGAGCC
TCGCCGGATCGCTCGCCATGACGGTCATCGACAAGCGCCACGAACTCTTCTATCTGCGCTGCCTTGGCCTCGAACGGCCG
CAGTTTATGACGATCTTTATCGTCGAAGGCGGGCTGACGGGTCTGGCCGGCACGACGCTTGGCTCGCTTTTAGCCTGGCT
CATCTGCAAAGCGCAAGAGCTGTGGGGCATCGTCCAGCTTCCCTCGAAGAGTGCCTTCATCATCAGCGCCTATCCCATCA
GCATGAAAACCGGCGACTTCCTCGCCGTTGGAGCCGCAGCCCTCTTCTTCACCCTGCTTGTCAGCCTCTATCCCGCCAGC
AAAGCCGCCGTCATTGCGACCAGCCAGTCGCTGGAAAACAAGATGGAGTGA

Upstream 100 bases:

>100_bases
GGGGGCGTGGCGGTGCTGACGCTGCTTTTCGCTTTCATTCCATCACGCGTTGCCGCTTCGCTCCAGCCCGCAACCGCACT
GACCACGTGAAAAGAAAACG

Downstream 100 bases:

>100_bases
GGGAGAAATGCAGAAGGGCGGTTTATGTGCCGCCCTTCCAGAAGATGGCTACCTCCATCAAAGATGTCTTTTCCCGCCCT
TAAATTTTCGTGAACTCTTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MKAGIWIAGRYSFARKRFRVINIISGISLAGIVVGVSTLLVVMSVLNGFQKLARDLFVTVEGPVQIVPAQGRSLVVSDSL
LAAIARLDGVETAHPFVEGQAIITASGKSELIMVRGLTAEAQRSLMQTTSTTQPYFSTDGISAGNLLAERLRLYPDEPVR
LFSPELISAGLQALSQPELMPALSMSDVRVQSSFSLQKLFDDRYVLAPVEMAQNILLFGRGRYSGIDIRGKSGVSDETLE
ARLREWISATHREKTLRVVTLRERHRDMFAVMQLEKWASFAVLMLVILVALLSLAGSLAMTVIDKRHELFYLRCLGLERP
QFMTIFIVEGGLTGLAGTTLGSLLAWLICKAQELWGIVQLPSKSAFIISAYPISMKTGDFLAVGAAALFFTLLVSLYPAS
KAAVIATSQSLENKME

Sequences:

>Translated_416_residues
MKAGIWIAGRYSFARKRFRVINIISGISLAGIVVGVSTLLVVMSVLNGFQKLARDLFVTVEGPVQIVPAQGRSLVVSDSL
LAAIARLDGVETAHPFVEGQAIITASGKSELIMVRGLTAEAQRSLMQTTSTTQPYFSTDGISAGNLLAERLRLYPDEPVR
LFSPELISAGLQALSQPELMPALSMSDVRVQSSFSLQKLFDDRYVLAPVEMAQNILLFGRGRYSGIDIRGKSGVSDETLE
ARLREWISATHREKTLRVVTLRERHRDMFAVMQLEKWASFAVLMLVILVALLSLAGSLAMTVIDKRHELFYLRCLGLERP
QFMTIFIVEGGLTGLAGTTLGSLLAWLICKAQELWGIVQLPSKSAFIISAYPISMKTGDFLAVGAAALFFTLLVSLYPAS
KAAVIATSQSLENKME
>Mature_416_residues
MKAGIWIAGRYSFARKRFRVINIISGISLAGIVVGVSTLLVVMSVLNGFQKLARDLFVTVEGPVQIVPAQGRSLVVSDSL
LAAIARLDGVETAHPFVEGQAIITASGKSELIMVRGLTAEAQRSLMQTTSTTQPYFSTDGISAGNLLAERLRLYPDEPVR
LFSPELISAGLQALSQPELMPALSMSDVRVQSSFSLQKLFDDRYVLAPVEMAQNILLFGRGRYSGIDIRGKSGVSDETLE
ARLREWISATHREKTLRVVTLRERHRDMFAVMQLEKWASFAVLMLVILVALLSLAGSLAMTVIDKRHELFYLRCLGLERP
QFMTIFIVEGGLTGLAGTTLGSLLAWLICKAQELWGIVQLPSKSAFIISAYPISMKTGDFLAVGAAALFFTLLVSLYPAS
KAAVIATSQSLENKME

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787360, Length=423, Percent_Identity=23.6406619385343, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1787362, Length=422, Percent_Identity=23.696682464455, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 45432; Mature: 45432

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAGIWIAGRYSFARKRFRVINIISGISLAGIVVGVSTLLVVMSVLNGFQKLARDLFVTV
CCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEE
EGPVQIVPAQGRSLVVSDSLLAAIARLDGVETAHPFVEGQAIITASGKSELIMVRGLTAE
CCCEEEEECCCCEEEEHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCEEEEECCCHH
AQRSLMQTTSTTQPYFSTDGISAGNLLAERLRLYPDEPVRLFSPELISAGLQALSQPELM
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCC
PALSMSDVRVQSSFSLQKLFDDRYVLAPVEMAQNILLFGRGRYSGIDIRGKSGVSDETLE
CCCCCCCEEECCCCCHHHHHCCCEEEEHHHHHCCEEEEECCCCCCEEECCCCCCCHHHHH
ARLREWISATHREKTLRVVTLRERHRDMFAVMQLEKWASFAVLMLVILVALLSLAGSLAM
HHHHHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVIDKRHELFYLRCLGLERPQFMTIFIVEGGLTGLAGTTLGSLLAWLICKAQELWGIVQL
HHHHCCHHEEEEEEECCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCEEEC
PSKSAFIISAYPISMKTGDFLAVGAAALFFTLLVSLYPASKAAVIATSQSLENKME
CCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHCCC
>Mature Secondary Structure
MKAGIWIAGRYSFARKRFRVINIISGISLAGIVVGVSTLLVVMSVLNGFQKLARDLFVTV
CCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEE
EGPVQIVPAQGRSLVVSDSLLAAIARLDGVETAHPFVEGQAIITASGKSELIMVRGLTAE
CCCEEEEECCCCEEEEHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCEEEEECCCHH
AQRSLMQTTSTTQPYFSTDGISAGNLLAERLRLYPDEPVRLFSPELISAGLQALSQPELM
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCC
PALSMSDVRVQSSFSLQKLFDDRYVLAPVEMAQNILLFGRGRYSGIDIRGKSGVSDETLE
CCCCCCCEEECCCCCHHHHHCCCEEEEHHHHHCCEEEEECCCCCCEEECCCCCCCHHHHH
ARLREWISATHREKTLRVVTLRERHRDMFAVMQLEKWASFAVLMLVILVALLSLAGSLAM
HHHHHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVIDKRHELFYLRCLGLERPQFMTIFIVEGGLTGLAGTTLGSLLAWLICKAQELWGIVQL
HHHHCCHHEEEEEEECCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCEEEC
PSKSAFIISAYPISMKTGDFLAVGAAALFFTLLVSLYPASKAAVIATSQSLENKME
CCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]