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The map label for this gene is prc [H]

Identifier: 21673880

GI number: 21673880

Start: 990650

End: 992677

Strand: Direct

Name: prc [H]

Synonym: CT1054

Alternate gene names: 21673880

Gene position: 990650-992677 (Clockwise)

Preceding gene: 21673878

Following gene: 21673883

Centisome position: 45.97

GC content: 54.93

Gene sequence:

>2028_bases
ATGGCTGCCGTTGGTCAAGCTGCTCAACCAGCCCTCCTCAAACCAACTCCGAACCAGGAGGAGGCCGCCCGTTACATCGC
CCAGTACCTGCTTCAGAACCATTACCGCAAGGTGCCGGTCAACGACTCGCTCTCCCAGCAGATTTTCAAACGCTACCTCG
ACAATCTCGACAACAACCGCAGTTACTTCACAGCGCCCGAGGTCGAAAAGCTCCGCCAGGAGTTCGGGGCTCACCTCGCT
GACGATTTCGTCTCCGGCAATCCCGCCGACGGTTTCGCCATCTACAACCAGTTCCTGAAACGGGCCAGAGAGAAGATGGC
GTATATGAAAAACGCGCTCGAAAAGACCACATTCAACTTTTCCTCCCCCGAAACGCTCGAACTGGAACGAAGCAAAACCG
CTCCCTGGCCAGCCAACGAGGCTGAGCTTCACGATCTGTGGCGCAAGGAGCTGAAGTATCAGTACCTGAGCGCCAAATAT
TCCGGCGAAAAGGGCAAAAACATCAAGTCTGAAGTCATGAAGACCCTTGACAACAGACTCAAAATCTTCAACCAGCAGAA
GCCCGAAGATGCTTTCCAGGCTTATATGTATGCCGTGACCACCTCGTTCGATCCGCATACCGACTACTTCTCGCCGGATG
AATACGAGAACTTCCAGATCGACATGAGCCGCTCGCTCGAAGGAATCGGCGCGAAGTTGCAGATGGAGAACGAATACACG
GTGGTGAACGAGATTATTCCCGGCGGCCCGGCCTTCAAAAGCAAACTTCTGAAGAAGGGCGACAAGATTGTCGGTGTTGG
ACAGGGCGACAAGGGAGAGATCATCGACGTGATCGGCTGGCGCATCAATGACGTGGTCAAAAAGATCAGAGGTCCCAAAG
GCACCGTTGTCAGGCTCAAGGTGCTTCCGGCCAGCCAGGCTGGCAAGGGGCCTGCAAAGATTATCCGGCTGGTGCGGGCC
AAGGTTGACTTGCAGGAGCAGGCCGCGCAGAAAAAGATCATTTATGACAACGGTCACAAAATTGGCGTTATCGTGCTTCC
GTCGTTCTATCTCGATTTCGAAGGCGAACGGCAGCAAAAGCATAACTACGCGAGTACTACAAAGGATGTGGCCAGAATCA
TCAACGAGCTGAAGCAGGAGAATGTGGAGGGAATCATCGTTGATCTGAGGGAAAACGGTGGTGGATCGCTCGAAGAGGCC
GTCAATGTCACCGGCCTGTTCACCGGCAGGGGGCCTGTCGTGCAGGTCAGCAACGCTCTCGGCGGCAAGATGGTGCTGAA
TGACGAAAATTACCCGATGCTTTACCGGGGGCCGCTGGTGGTGCTGGTCAACCGCTACAGCGCGTCGGCCTCGGAGATTT
TCGCCGCGGCGATCCAGGATTACGGGCGAGGACTCATCGTTGGAGACAGAACCTTCGGCAAGGGTACCGTGCAGAGCATC
GTCACCATCCAGAGACCATTCAGCATGTTCATGAAACAGGCTGACCTCGGCCAGCTCAAGTTGACCATCGCCAAGTTCTA
CCGCATCTCCGGCGGTAGTACCCAGCATATCGGTGTTCTGCCGGATATCGTTCTTCCGTCCCTGATCGACCCGGAGGTGG
TGGGTGAAGATACCTACACCAGCAGTCTGCCCTGGACAACCATCTCAAGGGCTGCTTATACACCATTAGGATTCGTCACC
AAAGAGGATATTGTTTTACTGAAGAAGGAGTTCGCCGAACAGTCCGCCAAAGACAAGCTCTACCAGTCCTATCTGGCCGA
TTTGGCAACCCTGAACCGTATCAGGCAGAAGAAGAGCGTGTCACTCCAGGAAAAAGGCTTTCAAGTGGAGAACAAGACCC
TGAAAGAGATACAGGATCGCTGGGGAGACCAGAATGCCGATACCGGGAAAAAGAAGAAAACGGATTTCATTCTGCAGGAG
GCTGCCAGAATTCTCGATGATCTCGTGGCGCTCAAGTCGCGTCCGGCAGTTCCCGCCGCGGCTCCGTTGGCAAGGCCTGC
CGTCAGGCGGGCGGTGCCCGTGAAATAA

Upstream 100 bases:

>100_bases
TTCACAAAAGCTTCACAGTCAGTTTATGAAAAAGATACGCAAGACCCTCTCTCCGATTCTGTTTTTTCTCCTGATGCTCA
CCCTTTCGTGGGATCAGTCC

Downstream 100 bases:

>100_bases
GCGGGCAGCAACATTCCAATAAAAAAGGCGCTCGGTGATGGAGCGCCTTTTTTGGTTCCGGGTTTGCCGAAACAGGGCGG
GCATAAAACCCGTCCCTACA

Product: carboxyl-terminal protease

Products: NA

Alternate protein names: C-terminal-processing peptidase; PRC protein; Protease Re [H]

Number of amino acids: Translated: 675; Mature: 674

Protein sequence:

>675_residues
MAAVGQAAQPALLKPTPNQEEAARYIAQYLLQNHYRKVPVNDSLSQQIFKRYLDNLDNNRSYFTAPEVEKLRQEFGAHLA
DDFVSGNPADGFAIYNQFLKRAREKMAYMKNALEKTTFNFSSPETLELERSKTAPWPANEAELHDLWRKELKYQYLSAKY
SGEKGKNIKSEVMKTLDNRLKIFNQQKPEDAFQAYMYAVTTSFDPHTDYFSPDEYENFQIDMSRSLEGIGAKLQMENEYT
VVNEIIPGGPAFKSKLLKKGDKIVGVGQGDKGEIIDVIGWRINDVVKKIRGPKGTVVRLKVLPASQAGKGPAKIIRLVRA
KVDLQEQAAQKKIIYDNGHKIGVIVLPSFYLDFEGERQQKHNYASTTKDVARIINELKQENVEGIIVDLRENGGGSLEEA
VNVTGLFTGRGPVVQVSNALGGKMVLNDENYPMLYRGPLVVLVNRYSASASEIFAAAIQDYGRGLIVGDRTFGKGTVQSI
VTIQRPFSMFMKQADLGQLKLTIAKFYRISGGSTQHIGVLPDIVLPSLIDPEVVGEDTYTSSLPWTTISRAAYTPLGFVT
KEDIVLLKKEFAEQSAKDKLYQSYLADLATLNRIRQKKSVSLQEKGFQVENKTLKEIQDRWGDQNADTGKKKKTDFILQE
AARILDDLVALKSRPAVPAAAPLARPAVRRAVPVK

Sequences:

>Translated_675_residues
MAAVGQAAQPALLKPTPNQEEAARYIAQYLLQNHYRKVPVNDSLSQQIFKRYLDNLDNNRSYFTAPEVEKLRQEFGAHLA
DDFVSGNPADGFAIYNQFLKRAREKMAYMKNALEKTTFNFSSPETLELERSKTAPWPANEAELHDLWRKELKYQYLSAKY
SGEKGKNIKSEVMKTLDNRLKIFNQQKPEDAFQAYMYAVTTSFDPHTDYFSPDEYENFQIDMSRSLEGIGAKLQMENEYT
VVNEIIPGGPAFKSKLLKKGDKIVGVGQGDKGEIIDVIGWRINDVVKKIRGPKGTVVRLKVLPASQAGKGPAKIIRLVRA
KVDLQEQAAQKKIIYDNGHKIGVIVLPSFYLDFEGERQQKHNYASTTKDVARIINELKQENVEGIIVDLRENGGGSLEEA
VNVTGLFTGRGPVVQVSNALGGKMVLNDENYPMLYRGPLVVLVNRYSASASEIFAAAIQDYGRGLIVGDRTFGKGTVQSI
VTIQRPFSMFMKQADLGQLKLTIAKFYRISGGSTQHIGVLPDIVLPSLIDPEVVGEDTYTSSLPWTTISRAAYTPLGFVT
KEDIVLLKKEFAEQSAKDKLYQSYLADLATLNRIRQKKSVSLQEKGFQVENKTLKEIQDRWGDQNADTGKKKKTDFILQE
AARILDDLVALKSRPAVPAAAPLARPAVRRAVPVK
>Mature_674_residues
AAVGQAAQPALLKPTPNQEEAARYIAQYLLQNHYRKVPVNDSLSQQIFKRYLDNLDNNRSYFTAPEVEKLRQEFGAHLAD
DFVSGNPADGFAIYNQFLKRAREKMAYMKNALEKTTFNFSSPETLELERSKTAPWPANEAELHDLWRKELKYQYLSAKYS
GEKGKNIKSEVMKTLDNRLKIFNQQKPEDAFQAYMYAVTTSFDPHTDYFSPDEYENFQIDMSRSLEGIGAKLQMENEYTV
VNEIIPGGPAFKSKLLKKGDKIVGVGQGDKGEIIDVIGWRINDVVKKIRGPKGTVVRLKVLPASQAGKGPAKIIRLVRAK
VDLQEQAAQKKIIYDNGHKIGVIVLPSFYLDFEGERQQKHNYASTTKDVARIINELKQENVEGIIVDLRENGGGSLEEAV
NVTGLFTGRGPVVQVSNALGGKMVLNDENYPMLYRGPLVVLVNRYSASASEIFAAAIQDYGRGLIVGDRTFGKGTVQSIV
TIQRPFSMFMKQADLGQLKLTIAKFYRISGGSTQHIGVLPDIVLPSLIDPEVVGEDTYTSSLPWTTISRAAYTPLGFVTK
EDIVLLKKEFAEQSAKDKLYQSYLADLATLNRIRQKKSVSLQEKGFQVENKTLKEIQDRWGDQNADTGKKKKTDFILQEA
ARILDDLVALKSRPAVPAAAPLARPAVRRAVPVK

Specific function: Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 (PBP3). May be involved in protection of the bacterium from thermal and osmotic stresses [H]

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1788134, Length=670, Percent_Identity=38.5074626865672, Blast_Score=432, Evalue=1e-122,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447
- InterPro:   IPR020992 [H]

Pfam domain/function: PF11818 DUF3340; PF00595 PDZ; PF03572 Peptidase_S41 [H]

EC number: =3.4.21.102 [H]

Molecular weight: Translated: 75484; Mature: 75353

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAVGQAAQPALLKPTPNQEEAARYIAQYLLQNHYRKVPVNDSLSQQIFKRYLDNLDNNR
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEECCCCCHHHHHHHHHHHHCCCCCC
SYFTAPEVEKLRQEFGAHLADDFVSGNPADGFAIYNQFLKRAREKMAYMKNALEKTTFNF
CEECCHHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SSPETLELERSKTAPWPANEAELHDLWRKELKYQYLSAKYSGEKGKNIKSEVMKTLDNRL
CCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
KIFNQQKPEDAFQAYMYAVTTSFDPHTDYFSPDEYENFQIDMSRSLEGIGAKLQMENEYT
HHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEHHHCCCCCCCEEEECCCEE
VVNEIIPGGPAFKSKLLKKGDKIVGVGQGDKGEIIDVIGWRINDVVKKIRGPKGTVVRLK
EHHHHCCCCHHHHHHHHHCCCCEEEECCCCCCCEEHHHCCHHHHHHHHHCCCCCCEEEEE
VLPASQAGKGPAKIIRLVRAKVDLQEQAAQKKIIYDNGHKIGVIVLPSFYLDFEGERQQK
EECCCCCCCCHHHHHHHHHHHCCHHHHHHCCCEEEECCCEEEEEEECCEEECCCCCHHHH
HNYASTTKDVARIINELKQENVEGIIVDLRENGGGSLEEAVNVTGLFTGRGPVVQVSNAL
HHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHCCEEEEEECCCCEEEECCCC
GGKMVLNDENYPMLYRGPLVVLVNRYSASASEIFAAAIQDYGRGLIVGDRTFGKGTVQSI
CCEEEECCCCCCEEEECCEEEEEECCCCCHHHHHHHHHHHHCCEEEEECCCCCCHHHHHH
VTIQRPFSMFMKQADLGQLKLTIAKFYRISGGSTQHIGVLPDIVLPSLIDPEVVGEDTYT
HHHHHHHHHHHHHCCCCHHHHHHHHHHEECCCCCCCCCCCHHHHCCCCCCCCCCCCCCCC
SSLPWTTISRAAYTPLGFVTKEDIVLLKKEFAEQSAKDKLYQSYLADLATLNRIRQKKSV
CCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SLQEKGFQVENKTLKEIQDRWGDQNADTGKKKKTDFILQEAARILDDLVALKSRPAVPAA
CHHHCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
APLARPAVRRAVPVK
CHHHHHHHHHCCCCC
>Mature Secondary Structure 
AAVGQAAQPALLKPTPNQEEAARYIAQYLLQNHYRKVPVNDSLSQQIFKRYLDNLDNNR
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEECCCCCHHHHHHHHHHHHCCCCCC
SYFTAPEVEKLRQEFGAHLADDFVSGNPADGFAIYNQFLKRAREKMAYMKNALEKTTFNF
CEECCHHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SSPETLELERSKTAPWPANEAELHDLWRKELKYQYLSAKYSGEKGKNIKSEVMKTLDNRL
CCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
KIFNQQKPEDAFQAYMYAVTTSFDPHTDYFSPDEYENFQIDMSRSLEGIGAKLQMENEYT
HHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEHHHCCCCCCCEEEECCCEE
VVNEIIPGGPAFKSKLLKKGDKIVGVGQGDKGEIIDVIGWRINDVVKKIRGPKGTVVRLK
EHHHHCCCCHHHHHHHHHCCCCEEEECCCCCCCEEHHHCCHHHHHHHHHCCCCCCEEEEE
VLPASQAGKGPAKIIRLVRAKVDLQEQAAQKKIIYDNGHKIGVIVLPSFYLDFEGERQQK
EECCCCCCCCHHHHHHHHHHHCCHHHHHHCCCEEEECCCEEEEEEECCEEECCCCCHHHH
HNYASTTKDVARIINELKQENVEGIIVDLRENGGGSLEEAVNVTGLFTGRGPVVQVSNAL
HHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHCCEEEEEECCCCEEEECCCC
GGKMVLNDENYPMLYRGPLVVLVNRYSASASEIFAAAIQDYGRGLIVGDRTFGKGTVQSI
CCEEEECCCCCCEEEECCEEEEEECCCCCHHHHHHHHHHHHCCEEEEECCCCCCHHHHHH
VTIQRPFSMFMKQADLGQLKLTIAKFYRISGGSTQHIGVLPDIVLPSLIDPEVVGEDTYT
HHHHHHHHHHHHHCCCCHHHHHHHHHHEECCCCCCCCCCCHHHHCCCCCCCCCCCCCCCC
SSLPWTTISRAAYTPLGFVTKEDIVLLKKEFAEQSAKDKLYQSYLADLATLNRIRQKKSV
CCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SLQEKGFQVENKTLKEIQDRWGDQNADTGKKKKTDFILQEAARILDDLVALKSRPAVPAA
CHHHCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
APLARPAVRRAVPVK
CHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1856173; 1729701; 9097040; 9278503; 1447154; 10049386; 7499412; 8576225 [H]