Click here to switch to the map view.

The map label for this gene is atpD-1

Identifier: 21673859

GI number: 21673859

Start: 969421

End: 970863

Strand: Reverse

Name: atpD-1

Synonym: CT1033

Alternate gene names: 21673859

Gene position: 970863-969421 (Counterclockwise)

Preceding gene: 21673860

Following gene: 21673858

Centisome position: 45.05

GC content: 62.86

Gene sequence:

>1443_bases
GTGGGAAAAACAGAGCCGGAACAGACAGGTATTGTCACCTCGATTCGCGGAAGCGTGGTCGATATGCGCTTCGACGAGCT
TCTGCCGTCGATCTACTCGGTTGTCAAAACCGGGCGCGAGATGGAGGTGACGGTCGAAATTCTCATGCAGCTCGACCGGC
GGCACGTCCGAGGCATCGCGCTCACGCCGACCGAGGGGCTGTGCCGTGGAATGAAAGCCCGCAACACCGGCTCGCCGCTC
AAAGCGCCCGTCGGCAAAGGCACACTGTCGCGCATGTTCGATGTGTTCGGCAACGCCATTGACCGGCGCGGCCCCGTAAC
CAACGTCACCTGGCGCTCGGTGCATGGCGCTCCTCCCCAACTCTCCCGCCGCTCGACAAAGTCCGAGGTGTTCGAGACGG
GCATCAAGATCATCGACCTGCTCGTACCGCTCGAACGCGGCGGCAAGGCGGGGCTGTTCGGCGGGGCGGGCGTCGGCAAG
ACCGTGCTCCTGACCGAGATGATCCACAACATGGTGAGCAAGGAGAGCGGCGTCAGCATCTTCTGCGGCATCGGCGAACG
GTGCCGCGAGGGCGAGGAGCTCTACCGCGACATGAGCGAGGCGGGCGTGCTCGACAACATGGTGATGGTGTTCGGCCAGA
TGAACGAACCGCCCGGCAGCCGCTTCCGCGTTGGCCTCACGGCGCTGACGATGGCCGAATACTTCCGTGACGACCTGCAT
CAGGAGGTGCTCTTGCTCATCGACAACATCTTCCGCTTCATCCAGGCCGGATCGGAGATTTCCGGCATGATAGGCCAGAT
GCCCTCCCGCCTCGGCTACCAGCCCACCATCGGCACCGAACTCTCCGCCCTTGAAGAGCGCATCGCCAACACCGGCACGG
GCGCGATCACCTCGATTCAGGCGGTGTACGTTCCGGCGGACGACTTCACTGACCCTGCGGCCGTGCACACCTTTTCGCAC
CTCTCGGCCTCTTTGGTGCTTTCGCGCAAACGCGCAGGAGAGGGGTTCTACCCGGCGGTTGATCCGCTCTCGTCAGGCTC
GAAGATGGCTGGCGAAAGCATCGTTGGCCGACGCCACTACGATCTGGCGCGCGAAGTGCGGCGGGTGCTCGCGCAGTACG
CCGAGCTGAAGGACATCATCGCCATGCTCGGCCTCGAACAGCTCTCGGCGGAGGATCGCCGCCTCGTCGGACGGGCGCGG
CGGCTCGAACGCTTCTTCACCCAACCCTTCTTCACGACCGAACAGTTCTCCGGCCTCGCGGGCAAAAGTGTCCCGATTGC
CAACACCATCGACGGTTGCGAACGCATCCTGCGCGACGAGTTCGAGAACTATCCTGAACGCGCACTCTATATGATCGGAA
GCATCGCCGAAGCGCAGGAAAAAACGGTGATCGAAACGACGATGAGTGAGTCCGTAGCCGCTAAACCGGAAGGAGGAAAT
TGA

Upstream 100 bases:

>100_bases
GGAATCGCTACTATTATTCTGATGCCTGACCGAGCTGGAGAGGCATCCGCACCACTGATTGATCGAGCGCCCCCCCCAAA
AAAACGGGAAGATCGTTACC

Downstream 100 bases:

>100_bases
GATGCTTGCCGACTCGATGCGCCTGAAAATTCTCCTGCCCTACAGAGTGTTCGCCATCAAAGAGCGGGTGCTGAACATCG
TCGCCGAAACGGAGCTGGGC

Product: F0F1 ATP synthase subunit beta

Products: NA

Alternate protein names: ATP synthase F1 sector subunit beta 1; F-ATPase subunit beta 1

Number of amino acids: Translated: 480; Mature: 479

Protein sequence:

>480_residues
MGKTEPEQTGIVTSIRGSVVDMRFDELLPSIYSVVKTGREMEVTVEILMQLDRRHVRGIALTPTEGLCRGMKARNTGSPL
KAPVGKGTLSRMFDVFGNAIDRRGPVTNVTWRSVHGAPPQLSRRSTKSEVFETGIKIIDLLVPLERGGKAGLFGGAGVGK
TVLLTEMIHNMVSKESGVSIFCGIGERCREGEELYRDMSEAGVLDNMVMVFGQMNEPPGSRFRVGLTALTMAEYFRDDLH
QEVLLLIDNIFRFIQAGSEISGMIGQMPSRLGYQPTIGTELSALEERIANTGTGAITSIQAVYVPADDFTDPAAVHTFSH
LSASLVLSRKRAGEGFYPAVDPLSSGSKMAGESIVGRRHYDLAREVRRVLAQYAELKDIIAMLGLEQLSAEDRRLVGRAR
RLERFFTQPFFTTEQFSGLAGKSVPIANTIDGCERILRDEFENYPERALYMIGSIAEAQEKTVIETTMSESVAAKPEGGN

Sequences:

>Translated_480_residues
MGKTEPEQTGIVTSIRGSVVDMRFDELLPSIYSVVKTGREMEVTVEILMQLDRRHVRGIALTPTEGLCRGMKARNTGSPL
KAPVGKGTLSRMFDVFGNAIDRRGPVTNVTWRSVHGAPPQLSRRSTKSEVFETGIKIIDLLVPLERGGKAGLFGGAGVGK
TVLLTEMIHNMVSKESGVSIFCGIGERCREGEELYRDMSEAGVLDNMVMVFGQMNEPPGSRFRVGLTALTMAEYFRDDLH
QEVLLLIDNIFRFIQAGSEISGMIGQMPSRLGYQPTIGTELSALEERIANTGTGAITSIQAVYVPADDFTDPAAVHTFSH
LSASLVLSRKRAGEGFYPAVDPLSSGSKMAGESIVGRRHYDLAREVRRVLAQYAELKDIIAMLGLEQLSAEDRRLVGRAR
RLERFFTQPFFTTEQFSGLAGKSVPIANTIDGCERILRDEFENYPERALYMIGSIAEAQEKTVIETTMSESVAAKPEGGN
>Mature_479_residues
GKTEPEQTGIVTSIRGSVVDMRFDELLPSIYSVVKTGREMEVTVEILMQLDRRHVRGIALTPTEGLCRGMKARNTGSPLK
APVGKGTLSRMFDVFGNAIDRRGPVTNVTWRSVHGAPPQLSRRSTKSEVFETGIKIIDLLVPLERGGKAGLFGGAGVGKT
VLLTEMIHNMVSKESGVSIFCGIGERCREGEELYRDMSEAGVLDNMVMVFGQMNEPPGSRFRVGLTALTMAEYFRDDLHQ
EVLLLIDNIFRFIQAGSEISGMIGQMPSRLGYQPTIGTELSALEERIANTGTGAITSIQAVYVPADDFTDPAAVHTFSHL
SASLVLSRKRAGEGFYPAVDPLSSGSKMAGESIVGRRHYDLAREVRRVLAQYAELKDIIAMLGLEQLSAEDRRLVGRARR
LERFFTQPFFTTEQFSGLAGKSVPIANTIDGCERILRDEFENYPERALYMIGSIAEAQEKTVIETTMSESVAAKPEGGN

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits

COG id: COG0055

COG function: function code C; F0F1-type ATP synthase, beta subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI32189394, Length=460, Percent_Identity=50.6521739130435, Blast_Score=487, Evalue=1e-137,
Organism=Homo sapiens, GI19913428, Length=348, Percent_Identity=24.7126436781609, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI19913426, Length=374, Percent_Identity=24.0641711229947, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI19913424, Length=315, Percent_Identity=27.9365079365079, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI50345984, Length=359, Percent_Identity=26.1838440111421, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI4757810, Length=359, Percent_Identity=26.1838440111421, Blast_Score=104, Evalue=2e-22,
Organism=Escherichia coli, GI1790170, Length=456, Percent_Identity=48.9035087719298, Blast_Score=459, Evalue=1e-130,
Organism=Escherichia coli, GI1790172, Length=346, Percent_Identity=26.878612716763, Blast_Score=124, Evalue=9e-30,
Organism=Escherichia coli, GI1788251, Length=318, Percent_Identity=31.1320754716981, Blast_Score=121, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI25144756, Length=465, Percent_Identity=49.0322580645161, Blast_Score=466, Evalue=1e-132,
Organism=Caenorhabditis elegans, GI17510931, Length=347, Percent_Identity=24.7838616714697, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17570191, Length=360, Percent_Identity=24.4444444444444, Blast_Score=114, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71988080, Length=371, Percent_Identity=25.0673854447439, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71988063, Length=371, Percent_Identity=25.0673854447439, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17565854, Length=331, Percent_Identity=26.2839879154079, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI71988074, Length=325, Percent_Identity=24.6153846153846, Blast_Score=89, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6322581, Length=456, Percent_Identity=49.1228070175439, Blast_Score=472, Evalue=1e-134,
Organism=Saccharomyces cerevisiae, GI6319603, Length=356, Percent_Identity=27.8089887640449, Blast_Score=114, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6319370, Length=407, Percent_Identity=25.3071253071253, Blast_Score=100, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6320016, Length=274, Percent_Identity=26.6423357664234, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24638766, Length=460, Percent_Identity=49.3478260869565, Blast_Score=474, Evalue=1e-134,
Organism=Drosophila melanogaster, GI28574560, Length=471, Percent_Identity=47.9830148619958, Blast_Score=455, Evalue=1e-128,
Organism=Drosophila melanogaster, GI281361666, Length=360, Percent_Identity=24.4444444444444, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24646341, Length=360, Percent_Identity=24.4444444444444, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI17136796, Length=360, Percent_Identity=24.4444444444444, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI20129479, Length=317, Percent_Identity=29.3375394321767, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24583992, Length=315, Percent_Identity=28.2539682539683, Blast_Score=109, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24583988, Length=315, Percent_Identity=28.2539682539683, Blast_Score=108, Evalue=7e-24,
Organism=Drosophila melanogaster, GI24583986, Length=315, Percent_Identity=28.2539682539683, Blast_Score=108, Evalue=7e-24,
Organism=Drosophila melanogaster, GI24583984, Length=315, Percent_Identity=28.2539682539683, Blast_Score=108, Evalue=7e-24,
Organism=Drosophila melanogaster, GI24658560, Length=346, Percent_Identity=25.1445086705202, Blast_Score=95, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24638768, Length=90, Percent_Identity=38.8888888888889, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPB1_CHLTE (Q8KDL4)

Other databases:

- EMBL:   AE006470
- RefSeq:   NP_661924.1
- ProteinModelPortal:   Q8KDL4
- SMR:   Q8KDL4
- GeneID:   1006982
- GenomeReviews:   AE006470_GR
- KEGG:   cte:CT1033
- NMPDR:   fig|194439.1.peg.1018
- TIGR:   CT1033
- HOGENOM:   HBG565875
- OMA:   AVHTFSH
- ProtClustDB:   PRK09280
- BioCyc:   CTEP194439:CT_1033-MONOMER
- HAMAP:   MF_01347
- InterPro:   IPR017691
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005722
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF8
- SMART:   SM00382
- TIGRFAMs:   TIGR03305
- TIGRFAMs:   TIGR01039

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 52609; Mature: 52478

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKTEPEQTGIVTSIRGSVVDMRFDELLPSIYSVVKTGREMEVTVEILMQLDRRHVRGIA
CCCCCCCCCCCEEHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCEE
LTPTEGLCRGMKARNTGSPLKAPVGKGTLSRMFDVFGNAIDRRGPVTNVTWRSVHGAPPQ
ECCCHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCC
LSRRSTKSEVFETGIKIIDLLVPLERGGKAGLFGGAGVGKTVLLTEMIHNMVSKESGVSI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEE
FCGIGERCREGEELYRDMSEAGVLDNMVMVFGQMNEPPGSRFRVGLTALTMAEYFRDDLH
EECCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHH
QEVLLLIDNIFRFIQAGSEISGMIGQMPSRLGYQPTIGTELSALEERIANTGTGAITSIQ
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCEEEE
AVYVPADDFTDPAAVHTFSHLSASLVLSRKRAGEGFYPAVDPLSSGSKMAGESIVGRRHY
EEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
DLAREVRRVLAQYAELKDIIAMLGLEQLSAEDRRLVGRARRLERFFTQPFFTTEQFSGLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCC
GKSVPIANTIDGCERILRDEFENYPERALYMIGSIAEAQEKTVIETTMSESVAAKPEGGN
CCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
GKTEPEQTGIVTSIRGSVVDMRFDELLPSIYSVVKTGREMEVTVEILMQLDRRHVRGIA
CCCCCCCCCCEEHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCEE
LTPTEGLCRGMKARNTGSPLKAPVGKGTLSRMFDVFGNAIDRRGPVTNVTWRSVHGAPPQ
ECCCHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCC
LSRRSTKSEVFETGIKIIDLLVPLERGGKAGLFGGAGVGKTVLLTEMIHNMVSKESGVSI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEE
FCGIGERCREGEELYRDMSEAGVLDNMVMVFGQMNEPPGSRFRVGLTALTMAEYFRDDLH
EECCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHH
QEVLLLIDNIFRFIQAGSEISGMIGQMPSRLGYQPTIGTELSALEERIANTGTGAITSIQ
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCEEEE
AVYVPADDFTDPAAVHTFSHLSASLVLSRKRAGEGFYPAVDPLSSGSKMAGESIVGRRHY
EEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
DLAREVRRVLAQYAELKDIIAMLGLEQLSAEDRRLVGRARRLERFFTQPFFTTEQFSGLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCC
GKSVPIANTIDGCERILRDEFENYPERALYMIGSIAEAQEKTVIETTMSESVAAKPEGGN
CCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12093901