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The map label for this gene is trxB [H]

Identifier: 21673671

GI number: 21673671

Start: 806577

End: 807512

Strand: Direct

Name: trxB [H]

Synonym: CT0842

Alternate gene names: 21673671

Gene position: 806577-807512 (Clockwise)

Preceding gene: 21673670

Following gene: 21673672

Centisome position: 37.43

GC content: 57.69

Gene sequence:

>936_bases
ATGGACAAAGATATCAGGGACGTCGTCATCATCGGAACCGGCCCTGCCGGATATACTTCTGCCATTTACACCGGACGGGC
CAATCTCAAGCCGCTGGTCATCGAGGGGCCCCAGCCCGGCGGGCAGCTCATGATTACCACCGATATCGAGAACTTTCCCG
GTTTTCCCGAAGGCATTCCCGGCCCGGAGCTGATGGGCAGAATGCGTGAACAGGCAGCACGTTTTGGCGTCGAGTTCCAG
TTTGGCAGCATCACTGAAGTCGATGTGTCGCGCAGTCCCTTCTCTCTGATGCTCGACAATGGCCAGGAGATTCTCGCCAG
AACGCTCATTATTGCCACCGGGGCGAACGCCAAATGGCTTGGCATCGAATCGGAGGAGAAGTACCGCGGGCGCGGCGTAT
CGGCGTGTGCAACCTGCGACGGATTCTTTTTTCGCAACTGCCGCGTGTTCGTGGTTGGCGGTGGCGATACGGCGATGGAG
GAGGCGCTTTACCTCACCAAGTTCGCTTCGGAGGTTGTGCTGGTGCATCGCCGCGAGGAGTTCCGCGCTTCCAAGATCAT
GAGCCTGCGGGCGAGCAAGAACGAGAAGATCACCACGATGCTCAACCAGGTGGTCGATGAGATTCTCGGTGACGATATGA
AGGTGACCGGCATCAGGCTCAAAAACGTCAAGACCGGCGAGCTGACCGAACATGCCTGTGATGGCGTTTTCATAGCGATC
GGCCATGAGCCGAACGCCAAACTTTTCAAAGGCCAGCTCGACATGGACGATTACGGCTACATTCTCACCAAAGATCACTC
CACAGAGACCAGTGTCAAAGGCGTTTTCGCCTGCGGCGACGTGCAGGACTTCACATACCGCCAGGCTGTTACTGCCGTCG
GCACCGGCTGCATGGCCGCCATCGAAGCCGAACGGTTCCTCGAATCGATACGTTGA

Upstream 100 bases:

>100_bases
GCATATCGGCTGATCTTCCATCCGTTTCTATTCTTTGCTATCCCGGTTCAAGCCGGGATAGTTTTGTTATAATCCCAACC
CTACCTCCCGGAGACAAACG

Downstream 100 bases:

>100_bases
CCGTTATCCCTTGTCCGGCAAAACCGGGGTTTTGAAGCTCCCGGTTTTGCCTTGCTTTTGCTTTGCCTGAAGCGGTCTCG
GTTCAGCCTCCCAACGTAAA

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MDKDIRDVVIIGTGPAGYTSAIYTGRANLKPLVIEGPQPGGQLMITTDIENFPGFPEGIPGPELMGRMREQAARFGVEFQ
FGSITEVDVSRSPFSLMLDNGQEILARTLIIATGANAKWLGIESEEKYRGRGVSACATCDGFFFRNCRVFVVGGGDTAME
EALYLTKFASEVVLVHRREEFRASKIMSLRASKNEKITTMLNQVVDEILGDDMKVTGIRLKNVKTGELTEHACDGVFIAI
GHEPNAKLFKGQLDMDDYGYILTKDHSTETSVKGVFACGDVQDFTYRQAVTAVGTGCMAAIEAERFLESIR

Sequences:

>Translated_311_residues
MDKDIRDVVIIGTGPAGYTSAIYTGRANLKPLVIEGPQPGGQLMITTDIENFPGFPEGIPGPELMGRMREQAARFGVEFQ
FGSITEVDVSRSPFSLMLDNGQEILARTLIIATGANAKWLGIESEEKYRGRGVSACATCDGFFFRNCRVFVVGGGDTAME
EALYLTKFASEVVLVHRREEFRASKIMSLRASKNEKITTMLNQVVDEILGDDMKVTGIRLKNVKTGELTEHACDGVFIAI
GHEPNAKLFKGQLDMDDYGYILTKDHSTETSVKGVFACGDVQDFTYRQAVTAVGTGCMAAIEAERFLESIR
>Mature_311_residues
MDKDIRDVVIIGTGPAGYTSAIYTGRANLKPLVIEGPQPGGQLMITTDIENFPGFPEGIPGPELMGRMREQAARFGVEFQ
FGSITEVDVSRSPFSLMLDNGQEILARTLIIATGANAKWLGIESEEKYRGRGVSACATCDGFFFRNCRVFVVGGGDTAME
EALYLTKFASEVVLVHRREEFRASKIMSLRASKNEKITTMLNQVVDEILGDDMKVTGIRLKNVKTGELTEHACDGVFIAI
GHEPNAKLFKGQLDMDDYGYILTKDHSTETSVKGVFACGDVQDFTYRQAVTAVGTGCMAAIEAERFLESIR

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=311, Percent_Identity=51.4469453376206, Blast_Score=323, Evalue=7e-90,
Organism=Escherichia coli, GI87081763, Length=311, Percent_Identity=32.1543408360129, Blast_Score=149, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6320560, Length=313, Percent_Identity=48.5623003194888, Blast_Score=299, Evalue=3e-82,
Organism=Saccharomyces cerevisiae, GI6321898, Length=312, Percent_Identity=47.4358974358974, Blast_Score=284, Evalue=1e-77,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34049; Mature: 34049

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKDIRDVVIIGTGPAGYTSAIYTGRANLKPLVIEGPQPGGQLMITTDIENFPGFPEGIP
CCCCCCEEEEEECCCCCCCEEEEECCCCCCEEEEECCCCCCEEEEEEECCCCCCCCCCCC
GPELMGRMREQAARFGVEFQFGSITEVDVSRSPFSLMLDNGQEILARTLIIATGANAKWL
CHHHHHHHHHHHHHCCEEEECCCEEEEECCCCCEEEEECCCHHHHEEEEEEEECCCEEEE
GIESEEKYRGRGVSACATCDGFFFRNCRVFVVGGGDTAMEEALYLTKFASEVVLVHRREE
ECCCCHHHCCCCCCEEECCCCEEECCEEEEEEECCCHHHHHHHHHHHHHHHHEEEECHHH
FRASKIMSLRASKNEKITTMLNQVVDEILGDDMKVTGIRLKNVKTGELTEHACDGVFIAI
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCHHHCCCEEEEEE
GHEPNAKLFKGQLDMDDYGYILTKDHSTETSVKGVFACGDVQDFTYRQAVTAVGTGCMAA
CCCCCCCEEEECCCCCCCCEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHCCHHHHH
IEAERFLESIR
HHHHHHHHHCC
>Mature Secondary Structure
MDKDIRDVVIIGTGPAGYTSAIYTGRANLKPLVIEGPQPGGQLMITTDIENFPGFPEGIP
CCCCCCEEEEEECCCCCCCEEEEECCCCCCEEEEECCCCCCEEEEEEECCCCCCCCCCCC
GPELMGRMREQAARFGVEFQFGSITEVDVSRSPFSLMLDNGQEILARTLIIATGANAKWL
CHHHHHHHHHHHHHCCEEEECCCEEEEECCCCCEEEEECCCHHHHEEEEEEEECCCEEEE
GIESEEKYRGRGVSACATCDGFFFRNCRVFVVGGGDTAMEEALYLTKFASEVVLVHRREE
ECCCCHHHCCCCCCEEECCCCEEECCEEEEEEECCCHHHHHHHHHHHHHHHHEEEECHHH
FRASKIMSLRASKNEKITTMLNQVVDEILGDDMKVTGIRLKNVKTGELTEHACDGVFIAI
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCHHHCCCEEEEEE
GHEPNAKLFKGQLDMDDYGYILTKDHSTETSVKGVFACGDVQDFTYRQAVTAVGTGCMAA
CCCCCCCEEEECCCCCCCCEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHCCHHHHH
IEAERFLESIR
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]