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The map label for this gene is oadA [H]

Identifier: 21673663

GI number: 21673663

Start: 794867

End: 796750

Strand: Direct

Name: oadA [H]

Synonym: CT0834

Alternate gene names: 21673663

Gene position: 794867-796750 (Clockwise)

Preceding gene: 21673662

Following gene: 21673664

Centisome position: 36.89

GC content: 61.41

Gene sequence:

>1884_bases
ATGAAAAAAATACGGTTCATGGATGTCTCATTCCGCGACGGGTTCCAGTCCTGTTACGGAGCAAGGGTCAAAACCGAGGA
TTTCCTGCCGGTGCTTGAAGCTGCCGTCGAGGCGGGCACCGATAACTTCGAGATCGGCGGAGGCGCGCGTTTCCAGAGCC
TCTACTTCTACTGTCAGGAAGACGCCTTCGAGATGATGGATGCCTGCCGCCGCGTGGTCGGCCCCGACATCAATCTCCAG
ACTTTGTCGCGAGGCGCAAACGTGGTCGGCCTCGTTTCGCAGTCGCGCGACATCATCGACCTGCACGCCAAAATGTTCAA
GAAGCATGGCGTCAGCACCATCCGCAACTTCGACGCGCTCATGGATGTGCGCAATCTCGCCTGGTCGGGCCAGTGCATCG
TCAACGCCGGGCTGAAGCACCAGGTGGTGATCGCCCTGATGGGCCTGCCGCCGGGGCTGAACGAGCCCTACTGCCACACG
CCGCAGTTCTACCTCGACAAGCTCAAGGAGATTCTCGACGCGGGCATTCCGTTCGACAGCGTCGCCTTCAAGGACGCCTC
CGGCACCACCACTCCCGCCGTGATCTACGAAACGATCAAGGGCGCTCGCAAGATGCTGCCCGAAGGCACCGTGCTCCAGT
TCCACACGCACGACACCGCCGGAATGGGCGTGGCCTGCAACTTTGCGGCCATCGAGGCGGGCATTGACATCATCGATCTG
GCGATGGCTCCGGTCAGCGGCGGCACCGCCGAGGTGGACATCCTTACCATGTGGCACCGCCTGCGCGGCACCGATTACAC
CCTCGACATCGATCAGGAGAAGTACCTCGAAGTCGAGCGGATGTTTATCGAGCACATGGACAAGTACTACATGCCGCCGG
AAGCCAAAGAGGTCAACCCGGTCATTCCGTTCTCGCCCATGCCGGGCGGCGCGCTGACGGCCAACACCCAGATGATGCGC
GACCACGGCACGTTGCACTTCTTCCCGGAGGTGATCCGCAACATGCGGGAAGTTGTCGCCAAGGGCGGCTTCGGCTCGTC
GGTGACGCCGGTTTCGCAGTTCTACTTCCAGCAGGCCTTCGCCAACACCGTGCAGGGGCCGTGGAAAAAGATCGTGGACG
GCTACGGCAAGATGGTGCTCGGCTACTTCGGCAAGACCCCGGCAGCCCCCGATCCGGAGGTGGTGGCGCTCGCCTCGGAA
CAGCTCGGCCTTGAGCCGACCGTTCAGGACGTGCACGACATCAACGACCGCAATCCCGATCTTGGCATCGAGCACAACCG
CAAGCTCCTCGAAGAGGCCGGATTGCCGGTGACCGACGAAAATATCTTTATCGCGGCCACCTGCGGCGCGAAGGGCATTA
GCTTCCTCAAGGGCGACAAGCCGATGGGCATCCGCTACAAAGCGGACGTCGAGGCGGAGGAGAAGGCCAAGCATAGCGAG
GAGGAGCTGAAGGTCACTTCGCATGGCAACTCGTTGCAGGATCGCCTCTCCGACCTCATCAAACCGGCTGGACGCAGCAA
CCTGTCAGGCAACTACATGGTGATGGTGGATGGCAAGTCGTTCAACGTGGTGATCGCCGATGGTATGGTCATGGCTCAGT
CGATCGCGTCCGGCGCGCAGCCTTTCGTGATGCCTGTGCCGACGGCGGTCTCCGCACCCCAGCAGCATCGGGGCACGCCG
GTCATGCCTTCCATGCCGGGCAACGTCTTCAAGATGGAGGTCGAAGCCGGTCAGAAGGTAGAGGAAGGGCAGGAGGTTGC
CGTCATGGAGGCTATGAAGATGGAGTCCCCGGTCAAAGCGCCAAAGTCCGGTATCGTTACGGTAGTCCTCGCTAAGCCCG
GAGACGCAGTTTCCGCCGCCCAGGCGCTGATGTATATCGAGTGA

Upstream 100 bases:

>100_bases
AACCGGAAAACAGTTTACTTTCTATGCCGCGCCGCGTCAGCCGCAACAGCCTGCCGCGGCGCGGCCATAATGGATCAGTT
AAAACCAGCGAGAGCGTTAT

Downstream 100 bases:

>100_bases
TTGGGCGCGGGATGGATTTCCGACACAGCACAATTTGAAAGGGCAGGCTCAACAGGTCTGCCTTTTGTTTGTCTCTGATT
AAGTGCTAAGTTTGGTGTAA

Product: oxaloacetate decarboxylase, alpha subunit

Products: NA

Alternate protein names: 2-oxoglutarate carboxylase alpha subunit [H]

Number of amino acids: Translated: 627; Mature: 627

Protein sequence:

>627_residues
MKKIRFMDVSFRDGFQSCYGARVKTEDFLPVLEAAVEAGTDNFEIGGGARFQSLYFYCQEDAFEMMDACRRVVGPDINLQ
TLSRGANVVGLVSQSRDIIDLHAKMFKKHGVSTIRNFDALMDVRNLAWSGQCIVNAGLKHQVVIALMGLPPGLNEPYCHT
PQFYLDKLKEILDAGIPFDSVAFKDASGTTTPAVIYETIKGARKMLPEGTVLQFHTHDTAGMGVACNFAAIEAGIDIIDL
AMAPVSGGTAEVDILTMWHRLRGTDYTLDIDQEKYLEVERMFIEHMDKYYMPPEAKEVNPVIPFSPMPGGALTANTQMMR
DHGTLHFFPEVIRNMREVVAKGGFGSSVTPVSQFYFQQAFANTVQGPWKKIVDGYGKMVLGYFGKTPAAPDPEVVALASE
QLGLEPTVQDVHDINDRNPDLGIEHNRKLLEEAGLPVTDENIFIAATCGAKGISFLKGDKPMGIRYKADVEAEEKAKHSE
EELKVTSHGNSLQDRLSDLIKPAGRSNLSGNYMVMVDGKSFNVVIADGMVMAQSIASGAQPFVMPVPTAVSAPQQHRGTP
VMPSMPGNVFKMEVEAGQKVEEGQEVAVMEAMKMESPVKAPKSGIVTVVLAKPGDAVSAAQALMYIE

Sequences:

>Translated_627_residues
MKKIRFMDVSFRDGFQSCYGARVKTEDFLPVLEAAVEAGTDNFEIGGGARFQSLYFYCQEDAFEMMDACRRVVGPDINLQ
TLSRGANVVGLVSQSRDIIDLHAKMFKKHGVSTIRNFDALMDVRNLAWSGQCIVNAGLKHQVVIALMGLPPGLNEPYCHT
PQFYLDKLKEILDAGIPFDSVAFKDASGTTTPAVIYETIKGARKMLPEGTVLQFHTHDTAGMGVACNFAAIEAGIDIIDL
AMAPVSGGTAEVDILTMWHRLRGTDYTLDIDQEKYLEVERMFIEHMDKYYMPPEAKEVNPVIPFSPMPGGALTANTQMMR
DHGTLHFFPEVIRNMREVVAKGGFGSSVTPVSQFYFQQAFANTVQGPWKKIVDGYGKMVLGYFGKTPAAPDPEVVALASE
QLGLEPTVQDVHDINDRNPDLGIEHNRKLLEEAGLPVTDENIFIAATCGAKGISFLKGDKPMGIRYKADVEAEEKAKHSE
EELKVTSHGNSLQDRLSDLIKPAGRSNLSGNYMVMVDGKSFNVVIADGMVMAQSIASGAQPFVMPVPTAVSAPQQHRGTP
VMPSMPGNVFKMEVEAGQKVEEGQEVAVMEAMKMESPVKAPKSGIVTVVLAKPGDAVSAAQALMYIE
>Mature_627_residues
MKKIRFMDVSFRDGFQSCYGARVKTEDFLPVLEAAVEAGTDNFEIGGGARFQSLYFYCQEDAFEMMDACRRVVGPDINLQ
TLSRGANVVGLVSQSRDIIDLHAKMFKKHGVSTIRNFDALMDVRNLAWSGQCIVNAGLKHQVVIALMGLPPGLNEPYCHT
PQFYLDKLKEILDAGIPFDSVAFKDASGTTTPAVIYETIKGARKMLPEGTVLQFHTHDTAGMGVACNFAAIEAGIDIIDL
AMAPVSGGTAEVDILTMWHRLRGTDYTLDIDQEKYLEVERMFIEHMDKYYMPPEAKEVNPVIPFSPMPGGALTANTQMMR
DHGTLHFFPEVIRNMREVVAKGGFGSSVTPVSQFYFQQAFANTVQGPWKKIVDGYGKMVLGYFGKTPAAPDPEVVALASE
QLGLEPTVQDVHDINDRNPDLGIEHNRKLLEEAGLPVTDENIFIAATCGAKGISFLKGDKPMGIRYKADVEAEEKAKHSE
EELKVTSHGNSLQDRLSDLIKPAGRSNLSGNYMVMVDGKSFNVVIADGMVMAQSIASGAQPFVMPVPTAVSAPQQHRGTP
VMPSMPGNVFKMEVEAGQKVEEGQEVAVMEAMKMESPVKAPKSGIVTVVLAKPGDAVSAAQALMYIE

Specific function: Unknown

COG id: COG5016

COG function: function code C; Pyruvate/oxaloacetate carboxyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=634, Percent_Identity=25.3943217665615, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI106049295, Length=634, Percent_Identity=25.3943217665615, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI106049292, Length=634, Percent_Identity=25.3943217665615, Blast_Score=119, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI17562816, Length=650, Percent_Identity=26, Blast_Score=122, Evalue=7e-28,
Organism=Saccharomyces cerevisiae, GI6319695, Length=649, Percent_Identity=26.6563944530046, Blast_Score=143, Evalue=7e-35,
Organism=Saccharomyces cerevisiae, GI6321376, Length=649, Percent_Identity=25.57781201849, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI281363050, Length=649, Percent_Identity=25.8859784283513, Blast_Score=138, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24652224, Length=649, Percent_Identity=25.8859784283513, Blast_Score=138, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24652222, Length=649, Percent_Identity=25.8859784283513, Blast_Score=138, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24652220, Length=649, Percent_Identity=25.8859784283513, Blast_Score=138, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24652218, Length=649, Percent_Identity=25.8859784283513, Blast_Score=138, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24652212, Length=649, Percent_Identity=25.8859784283513, Blast_Score=138, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24652210, Length=649, Percent_Identity=25.8859784283513, Blast_Score=138, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24652214, Length=649, Percent_Identity=25.8859784283513, Blast_Score=138, Evalue=1e-32,
Organism=Drosophila melanogaster, GI19921944, Length=649, Percent_Identity=25.8859784283513, Blast_Score=138, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24652216, Length=649, Percent_Identity=25.8859784283513, Blast_Score=138, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001882
- InterPro:   IPR000089
- InterPro:   IPR003379
- InterPro:   IPR000891
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00364 Biotin_lipoyl; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =6.4.1.7 [H]

Molecular weight: Translated: 68430; Mature: 68430

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS50991 PYR_CT ; PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIRFMDVSFRDGFQSCYGARVKTEDFLPVLEAAVEAGTDNFEIGGGARFQSLYFYCQE
CCCEEEEECHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEECCCCCEEEHEEEEEHH
DAFEMMDACRRVVGPDINLQTLSRGANVVGLVSQSRDIIDLHAKMFKKHGVSTIRNFDAL
HHHHHHHHHHHHHCCCCCHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCHHHHHHHHHH
MDVRNLAWSGQCIVNAGLKHQVVIALMGLPPGLNEPYCHTPQFYLDKLKEILDAGIPFDS
HHHHHHCCCCCEEEECCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
VAFKDASGTTTPAVIYETIKGARKMLPEGTVLQFHTHDTAGMGVACNFAAIEAGIDIIDL
EEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEHHHHHCCCCEEEH
AMAPVSGGTAEVDILTMWHRLRGTDYTLDIDQEKYLEVERMFIEHMDKYYMPPEAKEVNP
EECCCCCCCCEEHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
VIPFSPMPGGALTANTQMMRDHGTLHFFPEVIRNMREVVAKGGFGSSVTPVSQFYFQQAF
CCCCCCCCCCCEECCCHHHHHCCCEEHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
ANTVQGPWKKIVDGYGKMVLGYFGKTPAAPDPEVVALASEQLGLEPTVQDVHDINDRNPD
HHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEHHHCCCCCCHHHHHHCCCCCCC
LGIEHNRKLLEEAGLPVTDENIFIAATCGAKGISFLKGDKPMGIRYKADVEAEEKAKHSE
CCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHCCCCCCCEEEECCCCHHHHHCCCH
EELKVTSHGNSLQDRLSDLIKPAGRSNLSGNYMVMVDGKSFNVVIADGMVMAQSIASGAQ
HHEEEECCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCEEEEEECCHHHHHHHHCCCC
PFVMPVPTAVSAPQQHRGTPVMPSMPGNVFKMEVEAGQKVEEGQEVAVMEAMKMESPVKA
CEEEECCCCCCCCHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCC
PKSGIVTVVLAKPGDAVSAAQALMYIE
CCCCEEEEEEECCCCHHHHHHHHHCCC
>Mature Secondary Structure
MKKIRFMDVSFRDGFQSCYGARVKTEDFLPVLEAAVEAGTDNFEIGGGARFQSLYFYCQE
CCCEEEEECHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEECCCCCEEEHEEEEEHH
DAFEMMDACRRVVGPDINLQTLSRGANVVGLVSQSRDIIDLHAKMFKKHGVSTIRNFDAL
HHHHHHHHHHHHHCCCCCHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCHHHHHHHHHH
MDVRNLAWSGQCIVNAGLKHQVVIALMGLPPGLNEPYCHTPQFYLDKLKEILDAGIPFDS
HHHHHHCCCCCEEEECCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
VAFKDASGTTTPAVIYETIKGARKMLPEGTVLQFHTHDTAGMGVACNFAAIEAGIDIIDL
EEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEHHHHHCCCCEEEH
AMAPVSGGTAEVDILTMWHRLRGTDYTLDIDQEKYLEVERMFIEHMDKYYMPPEAKEVNP
EECCCCCCCCEEHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
VIPFSPMPGGALTANTQMMRDHGTLHFFPEVIRNMREVVAKGGFGSSVTPVSQFYFQQAF
CCCCCCCCCCCEECCCHHHHHCCCEEHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
ANTVQGPWKKIVDGYGKMVLGYFGKTPAAPDPEVVALASEQLGLEPTVQDVHDINDRNPD
HHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEHHHCCCCCCHHHHHHCCCCCCC
LGIEHNRKLLEEAGLPVTDENIFIAATCGAKGISFLKGDKPMGIRYKADVEAEEKAKHSE
CCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHCCCCCCCEEEECCCCHHHHHCCCH
EELKVTSHGNSLQDRLSDLIKPAGRSNLSGNYMVMVDGKSFNVVIADGMVMAQSIASGAQ
HHEEEECCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCEEEEEECCHHHHHHHHCCCC
PFVMPVPTAVSAPQQHRGTPVMPSMPGNVFKMEVEAGQKVEEGQEVAVMEAMKMESPVKA
CEEEECCCCCCCCHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCC
PKSGIVTVVLAKPGDAVSAAQALMYIE
CCCCEEEEEEECCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA