Click here to switch to the map view.

The map label for this gene is tolB

Identifier: 21673468

GI number: 21673468

Start: 636070

End: 637374

Strand: Direct

Name: tolB

Synonym: CT0636

Alternate gene names: 21673468

Gene position: 636070-637374 (Clockwise)

Preceding gene: 21673467

Following gene: 21673469

Centisome position: 29.52

GC content: 51.88

Gene sequence:

>1305_bases
ATGAGAAGCACCAGAAATTCATTCGCCTGTCTCTGCATCATGCTGTTCGGTATGCTCTTCGTGCCATTCACGCTCAGAGC
TGAAGAGGTTGGTGAATACATTGCTATCCGTAAAGAGGGTGCCAGCAGGATTGCGGTCGTCCTTGACAAAACATCTGCCG
ACGGTGGCAAGCAGAGGGAGTGGGCCAGAAGTCTTGATGTTACTATCAATAAGGGACTCGATTTCACCGGTCTGTTCAAT
CTGCTGCCGGCCCCTCTGAATATCAGGAATGGTCAGAATGGCGGGCTGAATTTTGCCTCCATTGCATCTGTTGGCGGCGA
TATTTACGCGGGCGGTTCTGTGACAAAGAGGTCGGGACGACCTGTTCTCGAAATGCATGTTTATGATTCATCCGGCAAGT
CGCTGCTCGCTCGTACCTATACTGGGGAAGAGTCCCAGCTCCGGGCGATCGGCTTGCGTTTCTGTGCCGATCTTGTCGAG
TTGCTTACTGGCAAACGCTCCGTTTTCGGCACCAGAATCGTTTTTGTCGCCAACCGCACCGGGAACAAAGAGATTTACAT
GTGTGATTTCGACGGAGAGAATGTCGTGCAGCTCACCAATTCGAGGTCAATCTCTCTTACGCCCGCAGTTTCGCCAGATG
GTACTTACATCGCATGGACGGATTATACGAGCGGTAAGCCTAATCTCTATATCAAGAATATCGCCACTGGCGCGAAAGTT
TCGGTCAACAAGCACGGGGTGTGCATCAGCCCGGCATGGCGTCCAGGCACGAACACGCTTGTGACAACACTCTCCTACGA
GGGCGATCAGGACCTTTACCTCATCAGGGCCGATGGCACGGTCGAGCGCCGGTTGACCAAAGGCGGCGGCATCGATGTGT
CTCCAACCTTTTCGCCAGACGGCTCGAAAATGGCGTTTGTCTCGACCCGGCAAGGTGGTCCACAGATTTTCATTCAGGAT
ATGAATAGTGGCCAGGTTCGGCGACTGACCTACAGTGGCATCTACAATACCCAGCCCTCATGGTCACCAAACGGCGACAA
AATCTTGTACTCTTCAATGCAAAAGAGTGGTGAAATCAATATATTTTCGATAAATGTCGACGGATCAGGTCTGCTTCAGC
TGACCAGTGGTTCAGGCAATAATGAGCATCCGTCGTGGTCTCCTGATGGAAGCATGATTGTTTTTTCATCGACCCGGGAT
GGCAGAAGACGGCTCTACGTCATGAATGCTGACGGTTCGAATCAGCGCCCTTTGCTGAATATGCAAGGTGAGCAGCAGCA
GCCATCATGGTCTGTAAGCAAGTAG

Upstream 100 bases:

>100_bases
TTGAGGTGTTTTTTACCGGTTTGCATGATTAAGGCCATGACTGTGTCCCGCCCGAACTGTTTTTACCTGTTACGAAAACA
TAAATTCATTTCCGACTGAT

Downstream 100 bases:

>100_bases
TGGCTCATTTTGTCAGCCTTTACTAAAGAGAGGGATTTATGACCGTTCCAGAATTACGCTAGAAGGTGATGCGCAGCTCA
GGAAAAATGCCGAGTAGATG

Product: TolB protein, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MRSTRNSFACLCIMLFGMLFVPFTLRAEEVGEYIAIRKEGASRIAVVLDKTSADGGKQREWARSLDVTINKGLDFTGLFN
LLPAPLNIRNGQNGGLNFASIASVGGDIYAGGSVTKRSGRPVLEMHVYDSSGKSLLARTYTGEESQLRAIGLRFCADLVE
LLTGKRSVFGTRIVFVANRTGNKEIYMCDFDGENVVQLTNSRSISLTPAVSPDGTYIAWTDYTSGKPNLYIKNIATGAKV
SVNKHGVCISPAWRPGTNTLVTTLSYEGDQDLYLIRADGTVERRLTKGGGIDVSPTFSPDGSKMAFVSTRQGGPQIFIQD
MNSGQVRRLTYSGIYNTQPSWSPNGDKILYSSMQKSGEINIFSINVDGSGLLQLTSGSGNNEHPSWSPDGSMIVFSSTRD
GRRRLYVMNADGSNQRPLLNMQGEQQQPSWSVSK

Sequences:

>Translated_434_residues
MRSTRNSFACLCIMLFGMLFVPFTLRAEEVGEYIAIRKEGASRIAVVLDKTSADGGKQREWARSLDVTINKGLDFTGLFN
LLPAPLNIRNGQNGGLNFASIASVGGDIYAGGSVTKRSGRPVLEMHVYDSSGKSLLARTYTGEESQLRAIGLRFCADLVE
LLTGKRSVFGTRIVFVANRTGNKEIYMCDFDGENVVQLTNSRSISLTPAVSPDGTYIAWTDYTSGKPNLYIKNIATGAKV
SVNKHGVCISPAWRPGTNTLVTTLSYEGDQDLYLIRADGTVERRLTKGGGIDVSPTFSPDGSKMAFVSTRQGGPQIFIQD
MNSGQVRRLTYSGIYNTQPSWSPNGDKILYSSMQKSGEINIFSINVDGSGLLQLTSGSGNNEHPSWSPDGSMIVFSSTRD
GRRRLYVMNADGSNQRPLLNMQGEQQQPSWSVSK
>Mature_434_residues
MRSTRNSFACLCIMLFGMLFVPFTLRAEEVGEYIAIRKEGASRIAVVLDKTSADGGKQREWARSLDVTINKGLDFTGLFN
LLPAPLNIRNGQNGGLNFASIASVGGDIYAGGSVTKRSGRPVLEMHVYDSSGKSLLARTYTGEESQLRAIGLRFCADLVE
LLTGKRSVFGTRIVFVANRTGNKEIYMCDFDGENVVQLTNSRSISLTPAVSPDGTYIAWTDYTSGKPNLYIKNIATGAKV
SVNKHGVCISPAWRPGTNTLVTTLSYEGDQDLYLIRADGTVERRLTKGGGIDVSPTFSPDGSKMAFVSTRQGGPQIFIQD
MNSGQVRRLTYSGIYNTQPSWSPNGDKILYSSMQKSGEINIFSINVDGSGLLQLTSGSGNNEHPSWSPDGSMIVFSSTRD
GRRRLYVMNADGSNQRPLLNMQGEQQQPSWSVSK

Specific function: Involved in the tonB-independent uptake of proteins

COG id: COG0823

COG function: function code U; Periplasmic component of the Tol biopolymer transport system

Gene ontology:

Cell location: Periplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tolB family

Homologues:

Organism=Escherichia coli, GI1786961, Length=308, Percent_Identity=29.2207792207792, Blast_Score=127, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI32564215, Length=193, Percent_Identity=24.8704663212435, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI32564217, Length=213, Percent_Identity=24.4131455399061, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TOLB_CHLTE (Q8KEQ0)

Other databases:

- EMBL:   AE006470
- RefSeq:   NP_661533.1
- ProteinModelPortal:   Q8KEQ0
- SMR:   Q8KEQ0
- GeneID:   1006270
- GenomeReviews:   AE006470_GR
- KEGG:   cte:CT0636
- NMPDR:   fig|194439.1.peg.627
- TIGR:   CT0636
- HOGENOM:   HBG644919
- OMA:   SFAPDSY
- ProtClustDB:   CLSK637407
- BioCyc:   CTEP194439:CT_0636-MONOMER
- HAMAP:   MF_00671
- InterPro:   IPR011659
- InterPro:   IPR014167
- InterPro:   IPR007195
- InterPro:   IPR015943
- Gene3D:   G3DSA:3.40.50.10070
- Gene3D:   G3DSA:2.130.10.10
- TIGRFAMs:   TIGR02800

Pfam domain/function: PF07676 PD40; PF04052 TolB_N; SSF52964 TolB_N

EC number: NA

Molecular weight: Translated: 47276; Mature: 47276

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSTRNSFACLCIMLFGMLFVPFTLRAEEVGEYIAIRKEGASRIAVVLDKTSADGGKQRE
CCCCCCHHHHHHHHHHHHHHCCEEEEHHHHCCEEEEEECCCCEEEEEEEECCCCCCCHHH
WARSLDVTINKGLDFTGLFNLLPAPLNIRNGQNGGLNFASIASVGGDIYAGGSVTKRSGR
HHHEECEEEECCCCCEEHHHHCCCCEEECCCCCCCCCHHHHHHCCCCEEECCCEEECCCC
PVLEMHVYDSSGKSLLARTYTGEESQLRAIGLRFCADLVELLTGKRSVFGTRIVFVANRT
CEEEEEEECCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECC
GNKEIYMCDFDGENVVQLTNSRSISLTPAVSPDGTYIAWTDYTSGKPNLYIKNIATGAKV
CCCEEEEEECCCCCEEEEECCCEEEEEECCCCCCCEEEEECCCCCCCCEEEEEECCCCEE
SVNKHGVCISPAWRPGTNTLVTTLSYEGDQDLYLIRADGTVERRLTKGGGIDVSPTFSPD
EECCCCEEECCCCCCCCCEEEEEEEECCCCCEEEEECCCCEEEHHHCCCCEECCCCCCCC
GSKMAFVSTRQGGPQIFIQDMNSGQVRRLTYSGIYNTQPSWSPNGDKILYSSMQKSGEIN
CCEEEEEEECCCCCEEEEEECCCCEEEEEEECCEECCCCCCCCCCCEEEEEHHHCCCCEE
IFSINVDGSGLLQLTSGSGNNEHPSWSPDGSMIVFSSTRDGRRRLYVMNADGSNQRPLLN
EEEEEECCCCEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCEEE
MQGEQQQPSWSVSK
CCCCCCCCCCCCCC
>Mature Secondary Structure
MRSTRNSFACLCIMLFGMLFVPFTLRAEEVGEYIAIRKEGASRIAVVLDKTSADGGKQRE
CCCCCCHHHHHHHHHHHHHHCCEEEEHHHHCCEEEEEECCCCEEEEEEEECCCCCCCHHH
WARSLDVTINKGLDFTGLFNLLPAPLNIRNGQNGGLNFASIASVGGDIYAGGSVTKRSGR
HHHEECEEEECCCCCEEHHHHCCCCEEECCCCCCCCCHHHHHHCCCCEEECCCEEECCCC
PVLEMHVYDSSGKSLLARTYTGEESQLRAIGLRFCADLVELLTGKRSVFGTRIVFVANRT
CEEEEEEECCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECC
GNKEIYMCDFDGENVVQLTNSRSISLTPAVSPDGTYIAWTDYTSGKPNLYIKNIATGAKV
CCCEEEEEECCCCCEEEEECCCEEEEEECCCCCCCEEEEECCCCCCCCEEEEEECCCCEE
SVNKHGVCISPAWRPGTNTLVTTLSYEGDQDLYLIRADGTVERRLTKGGGIDVSPTFSPD
EECCCCEEECCCCCCCCCEEEEEEEECCCCCEEEEECCCCEEEHHHCCCCEECCCCCCCC
GSKMAFVSTRQGGPQIFIQDMNSGQVRRLTYSGIYNTQPSWSPNGDKILYSSMQKSGEIN
CCEEEEEEECCCCCEEEEEECCCCEEEEEEECCEECCCCCCCCCCCEEEEEHHHCCCCEE
IFSINVDGSGLLQLTSGSGNNEHPSWSPDGSMIVFSSTRDGRRRLYVMNADGSNQRPLLN
EEEEEECCCCEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCEEE
MQGEQQQPSWSVSK
CCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12093901