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The map label for this gene is cdd [H]

Identifier: 21673423

GI number: 21673423

Start: 591492

End: 591938

Strand: Direct

Name: cdd [H]

Synonym: CT0588

Alternate gene names: 21673423

Gene position: 591492-591938 (Clockwise)

Preceding gene: 21673422

Following gene: 21673424

Centisome position: 27.45

GC content: 63.53

Gene sequence:

>447_bases
ATGAACAGAGACCACGAATTCATGGCGCTGGCCCTCGAACAGGCCCGGAAGAGCTACGATGAGGGCGGCGTACCCGTCGG
GGCGGTGATGGTCGAAAATGGTAAGGTGCTTGCCGCCGGGCACAACCAGCGCGTGCAGCAGGGCGACCCGATTGCCCACG
GCGAGATGGACTGTATCCGCAAGGCGGGCCGCTGTGCCCGGTACGACACCGTGACGCTCTACACGACGCTCTCTCCTTGC
ATGATGTGCGCAGGCGCAATCGTCCAGTTCGGCATCGGGCGGGTCGTCGTGGGCGAAGACCGGAATTTCAAGGGCAACGC
TGGATTTCTGCGCGAGCACGGTGTCGAAGTCTCGCTTCTCGACGACGAAGGGTGCCGAAGCCTCATGGACGCCTTCATCG
CCGAACGCCCCGACCTGTGGGACGAAGACATCGCAGGGAACGGGTGA

Upstream 100 bases:

>100_bases
GTTTTCAACTATTCGCTTGAAGGCAAGAAGATGAACTCGATTTTCCGCAAGTCCCCGGTTCACGGCTGGTACTTCTTCAT
TGCCCAGCAGTGCAAGTAAG

Downstream 100 bases:

>100_bases
GAACGCCTCCAGCATTTGGTTAAAGACAGCAATCATTTTATGAATTCAACGAACATGAATTTTGTTATCCGCCTGAAAGA
TGTGGTCGATGCGATAGACC

Product: cytosine deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MNRDHEFMALALEQARKSYDEGGVPVGAVMVENGKVLAAGHNQRVQQGDPIAHGEMDCIRKAGRCARYDTVTLYTTLSPC
MMCAGAIVQFGIGRVVVGEDRNFKGNAGFLREHGVEVSLLDDEGCRSLMDAFIAERPDLWDEDIAGNG

Sequences:

>Translated_148_residues
MNRDHEFMALALEQARKSYDEGGVPVGAVMVENGKVLAAGHNQRVQQGDPIAHGEMDCIRKAGRCARYDTVTLYTTLSPC
MMCAGAIVQFGIGRVVVGEDRNFKGNAGFLREHGVEVSLLDDEGCRSLMDAFIAERPDLWDEDIAGNG
>Mature_148_residues
MNRDHEFMALALEQARKSYDEGGVPVGAVMVENGKVLAAGHNQRVQQGDPIAHGEMDCIRKAGRCARYDTVTLYTTLSPC
MMCAGAIVQFGIGRVVVGEDRNFKGNAGFLREHGVEVSLLDDEGCRSLMDAFIAERPDLWDEDIAGNG

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Escherichia coli, GI145693172, Length=150, Percent_Identity=39.3333333333333, Blast_Score=92, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17554608, Length=110, Percent_Identity=39.0909090909091, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17541138, Length=109, Percent_Identity=37.6146788990826, Blast_Score=70, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6325319, Length=147, Percent_Identity=47.6190476190476, Blast_Score=133, Evalue=9e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 16103; Mature: 16103

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
8.1 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
8.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRDHEFMALALEQARKSYDEGGVPVGAVMVENGKVLAAGHNQRVQQGDPIAHGEMDCIR
CCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCEEEEECCCCCCCCCCCCCCCCHHHHH
KAGRCARYDTVTLYTTLSPCMMCAGAIVQFGIGRVVVGEDRNFKGNAGFLREHGVEVSLL
HCCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCHHHCCCEEEEE
DDEGCRSLMDAFIAERPDLWDEDIAGNG
CCHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MNRDHEFMALALEQARKSYDEGGVPVGAVMVENGKVLAAGHNQRVQQGDPIAHGEMDCIR
CCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCEEEEECCCCCCCCCCCCCCCCHHHHH
KAGRCARYDTVTLYTTLSPCMMCAGAIVQFGIGRVVVGEDRNFKGNAGFLREHGVEVSLL
HCCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCHHHCCCEEEEE
DDEGCRSLMDAFIAERPDLWDEDIAGNG
CCHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]