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The map label for this gene is 21673259

Identifier: 21673259

GI number: 21673259

Start: 436969

End: 438918

Strand: Direct

Name: 21673259

Synonym: CT0420

Alternate gene names: NA

Gene position: 436969-438918 (Clockwise)

Preceding gene: 21673258

Following gene: 21673260

Centisome position: 20.28

GC content: 62.82

Gene sequence:

>1950_bases
ATGAAAAGAAAATATTTCCCGTTTTCGGCCATTCTCGGCCAGGAGGATCTCAAAAAAGCGTTGCTGCTCAATGCCGTCAA
TCCCCGCATTGGCGGTGTGCTGGTGCGCGGCGAGAAGGGCACGGCCAAATCGACCGCCGTCCGGGCGCTCGGCGCACTGC
TTGCCGCAGCGAGGAACGGCAGCGGTGGTGAAGGCGAGGTGGTCGTGACGCTGCCGCTCAACGCCACCGAGGAGATGGTG
GCCGGAGGCATCGATTTCCAGCAGACCATGAAGGAGGGGCGGCGCGTATTCCAGCCGGGCCTGCTCGCCAAAGCCCACAA
GGGGATTCTGTATGTCGATGAAGTGAACCTGCTTGATGACCATCTGGTCGATATCGTCCTCGATGCGGCTTCCTCCGGCG
AGAACCGCGTCGAGCGCGAAGGGATCACCCTCAGCCATCCCTCCCTTTTCGTGCTGGCCGGTACGATGAATCCCGAGGAG
GGCGAGCTGCGCCCGCAGTTGCTCGACCGTTTCGGACTCTGCGTGGAGGTGCGCGGCGAGGCCGATCCAGCGCTTCGCGT
CGATCTGATGTTGCGCAGGGAGGCGTTCGACCGTGAGCCTGAAGAGTTTTCGGAGAGGTATCGTGCCGAGGAGGAGCGGC
TTGGGCGAACTATTGCCGATGCGCAGTCGCTTCTGCCGTCAGTCAGGATTCCGTCGCATTTGCGCGGCTTCATTTCGGAG
CTGTGCCGGAACAGCAATGTCGCCGGGCACCGGGCAGACCTGGTGATCGAGCAGGCGGCGCGGGCCAACGCCGCTCTGCG
CGGGTCGCGCGAGGTGTCGGTGGAGGATGTCACGAAGGTCGCGGGCTTTGCGCTCGTGCATCGCCGCCGCGATCCGGTTC
CGCCGCCCGAACAGAAGCCGCAGGAGCCGGAGCGCCAGGAGGAGCAGTCGCGTGACGAGCAGTCCCGGCAGGAGAAGCCG
GAAGAGCGTGGCGATGAGCCGCAGCAGCCACAGGAGGGCGACGACAGGCGGGACGGCAACGACGATTCCGGCAATGAAGA
GAGGTCGCAGCCAGAAAACAGGGATGCCGCCGAACAGCAGGAGCGGCCCGATAACGAAGGTCAGGACGAGCTGTTCAGCA
TCGGCCAGTCCTTTCGTGTTCGCAGCATCGCCACTCCGAAAGATCGCAAGATGCGGCGCGGCTCCGGAAAGCGTTCGCGG
TCGCGGGTTTCGCAGAAGCAGGGGCGCTATACCAAGAGCACCATGCCGCGCGGCAACAACGACATAGCGCTCGACGCCAC
GCTCAGGGCCGCCGCGCCGTTCCAGCGCCATCGTGAAAACCCCAACGGCATGGCGGTGGTGTTGCAGAACGAGGATATCC
GCGAAAAGATCAGGGAGAAGCGCCTCGGCAACCTGCTGATTTTCGTGGTCGATGCGAGCGGTTCGATGGGCGCGCGGGGC
CGCATGGCCGCCTCGAAAGGGGCGGTCATGTCGCTCTTGCTCGACGCTTACCAGAAGCGCGACAAGCTGGCGATGGTCTC
GTTCCGCAAGAATGAGGCGTTCGTCAATCTGCCGGTCACCTCCTCCATCGAGCTTGCCGCCCGGATGCTCAAGGAGATGC
CGGTGGGCGGGCGCACCCCCTTTTCCGCCGGTCTGCTCAAGGGGTACGAAATCGCTCAAAACTATCTCCGCAAAGAGCCG
GGCGGACGACCGCTTATCATCCTTGTCACCGACGGCAAAGCGAATCGGGCCATCGGGCAGGGCAAGCCGCTCGACGAAGT
GTTCACCATCTCCGAAAAGATTTCCCGCGAGGAGCGAATCCGCTTTCTCGTCGTCGATACCGAAGAGCCTGGTCTGGTCA
CTTTTGGTCTCGCCAAAAAAATCGCCGGTCTGCTCGATGCCTGGTACTACCGCATCGACGACTTGCGTGCAGACACCCTT
GTTTCCATCGTAAAAACCATGATGCCATGA

Upstream 100 bases:

>100_bases
AACCTGCTCGACCGCGAGTATCTCTATGTCGATGGCTATGACGCGCCGCCCCGTGAGTGGAAGATTGGCATGAACTACAC
TTTCTGTCTGAACTGAAATC

Downstream 100 bases:

>100_bases
AAAAGAACTACACCTATCCCTTTACGGCCATTGTCGGTCAGGAAGAGATGAAGCTCGCGCTGATTCTCAACATCATCAAT
CCGGCCATCTCCGGCGTGCT

Product: magnesium-chelatase subunit D/I family protein

Products: ADP; phosphate; Mg-protoporphyrin IX; H+

Alternate protein names: NA

Number of amino acids: Translated: 649; Mature: 649

Protein sequence:

>649_residues
MKRKYFPFSAILGQEDLKKALLLNAVNPRIGGVLVRGEKGTAKSTAVRALGALLAAARNGSGGEGEVVVTLPLNATEEMV
AGGIDFQQTMKEGRRVFQPGLLAKAHKGILYVDEVNLLDDHLVDIVLDAASSGENRVEREGITLSHPSLFVLAGTMNPEE
GELRPQLLDRFGLCVEVRGEADPALRVDLMLRREAFDREPEEFSERYRAEEERLGRTIADAQSLLPSVRIPSHLRGFISE
LCRNSNVAGHRADLVIEQAARANAALRGSREVSVEDVTKVAGFALVHRRRDPVPPPEQKPQEPERQEEQSRDEQSRQEKP
EERGDEPQQPQEGDDRRDGNDDSGNEERSQPENRDAAEQQERPDNEGQDELFSIGQSFRVRSIATPKDRKMRRGSGKRSR
SRVSQKQGRYTKSTMPRGNNDIALDATLRAAAPFQRHRENPNGMAVVLQNEDIREKIREKRLGNLLIFVVDASGSMGARG
RMAASKGAVMSLLLDAYQKRDKLAMVSFRKNEAFVNLPVTSSIELAARMLKEMPVGGRTPFSAGLLKGYEIAQNYLRKEP
GGRPLIILVTDGKANRAIGQGKPLDEVFTISEKISREERIRFLVVDTEEPGLVTFGLAKKIAGLLDAWYYRIDDLRADTL
VSIVKTMMP

Sequences:

>Translated_649_residues
MKRKYFPFSAILGQEDLKKALLLNAVNPRIGGVLVRGEKGTAKSTAVRALGALLAAARNGSGGEGEVVVTLPLNATEEMV
AGGIDFQQTMKEGRRVFQPGLLAKAHKGILYVDEVNLLDDHLVDIVLDAASSGENRVEREGITLSHPSLFVLAGTMNPEE
GELRPQLLDRFGLCVEVRGEADPALRVDLMLRREAFDREPEEFSERYRAEEERLGRTIADAQSLLPSVRIPSHLRGFISE
LCRNSNVAGHRADLVIEQAARANAALRGSREVSVEDVTKVAGFALVHRRRDPVPPPEQKPQEPERQEEQSRDEQSRQEKP
EERGDEPQQPQEGDDRRDGNDDSGNEERSQPENRDAAEQQERPDNEGQDELFSIGQSFRVRSIATPKDRKMRRGSGKRSR
SRVSQKQGRYTKSTMPRGNNDIALDATLRAAAPFQRHRENPNGMAVVLQNEDIREKIREKRLGNLLIFVVDASGSMGARG
RMAASKGAVMSLLLDAYQKRDKLAMVSFRKNEAFVNLPVTSSIELAARMLKEMPVGGRTPFSAGLLKGYEIAQNYLRKEP
GGRPLIILVTDGKANRAIGQGKPLDEVFTISEKISREERIRFLVVDTEEPGLVTFGLAKKIAGLLDAWYYRIDDLRADTL
VSIVKTMMP
>Mature_649_residues
MKRKYFPFSAILGQEDLKKALLLNAVNPRIGGVLVRGEKGTAKSTAVRALGALLAAARNGSGGEGEVVVTLPLNATEEMV
AGGIDFQQTMKEGRRVFQPGLLAKAHKGILYVDEVNLLDDHLVDIVLDAASSGENRVEREGITLSHPSLFVLAGTMNPEE
GELRPQLLDRFGLCVEVRGEADPALRVDLMLRREAFDREPEEFSERYRAEEERLGRTIADAQSLLPSVRIPSHLRGFISE
LCRNSNVAGHRADLVIEQAARANAALRGSREVSVEDVTKVAGFALVHRRRDPVPPPEQKPQEPERQEEQSRDEQSRQEKP
EERGDEPQQPQEGDDRRDGNDDSGNEERSQPENRDAAEQQERPDNEGQDELFSIGQSFRVRSIATPKDRKMRRGSGKRSR
SRVSQKQGRYTKSTMPRGNNDIALDATLRAAAPFQRHRENPNGMAVVLQNEDIREKIREKRLGNLLIFVVDASGSMGARG
RMAASKGAVMSLLLDAYQKRDKLAMVSFRKNEAFVNLPVTSSIELAARMLKEMPVGGRTPFSAGLLKGYEIAQNYLRKEP
GGRPLIILVTDGKANRAIGQGKPLDEVFTISEKISREERIRFLVVDTEEPGLVTFGLAKKIAGLLDAWYYRIDDLRADTL
VSIVKTMMP

Specific function: Unknown

COG id: COG1239

COG function: function code H; Mg-chelatase subunit ChlI

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 VWFA domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011704
- InterPro:   IPR012804
- InterPro:   IPR002035 [H]

Pfam domain/function: PF07728 AAA_5; PF00092 VWA [H]

EC number: 6.6.1.1

Molecular weight: Translated: 72106; Mature: 72106

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: PS50234 VWFA ; PS00676 SIGMA54_INTERACT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRKYFPFSAILGQEDLKKALLLNAVNPRIGGVLVRGEKGTAKSTAVRALGALLAAARNG
CCCCCCCHHHHHCHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCC
SGGEGEVVVTLPLNATEEMVAGGIDFQQTMKEGRRVFQPGLLAKAHKGILYVDEVNLLDD
CCCCCEEEEEECCCCHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHCCCEEEEECCCHHHH
HLVDIVLDAASSGENRVEREGITLSHPSLFVLAGTMNPEEGELRPQLLDRFGLCVEVRGE
HHHHHHHHCCCCCCCHHHHCCEEEECCCEEEEEECCCCCCCCCCHHHHHHCCCEEEECCC
ADPALRVDLMLRREAFDREPEEFSERYRAEEERLGRTIADAQSLLPSVRIPSHLRGFISE
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
LCRNSNVAGHRADLVIEQAARANAALRGSREVSVEDVTKVAGFALVHRRRDPVPPPEQKP
HHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
QEPERQEEQSRDEQSRQEKPEERGDEPQQPQEGDDRRDGNDDSGNEERSQPENRDAAEQQ
CCCHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCHHHHH
ERPDNEGQDELFSIGQSFRVRSIATPKDRKMRRGSGKRSRSRVSQKQGRYTKSTMPRGNN
HCCCCCCHHHHHHHCHHHEEEECCCCHHHHHHCCCCHHHHHHHHHHHCCCCHHCCCCCCC
DIALDATLRAAAPFQRHRENPNGMAVVLQNEDIREKIREKRLGNLLIFVVDASGSMGARG
CEEEEEHHHHHCCHHHHCCCCCCEEEEEECCHHHHHHHHHHCCCEEEEEEECCCCCCCCC
RMAASKGAVMSLLLDAYQKRDKLAMVSFRKNEAFVNLPVTSSIELAARMLKEMPVGGRTP
CCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEEECCCCCHHHHHHHHHHHCCCCCCCC
FSAGLLKGYEIAQNYLRKEPGGRPLIILVTDGKANRAIGQGKPLDEVFTISEKISREERI
CHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCHHHCE
RFLVVDTEEPGLVTFGLAKKIAGLLDAWYYRIDDLRADTLVSIVKTMMP
EEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKRKYFPFSAILGQEDLKKALLLNAVNPRIGGVLVRGEKGTAKSTAVRALGALLAAARNG
CCCCCCCHHHHHCHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCC
SGGEGEVVVTLPLNATEEMVAGGIDFQQTMKEGRRVFQPGLLAKAHKGILYVDEVNLLDD
CCCCCEEEEEECCCCHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHCCCEEEEECCCHHHH
HLVDIVLDAASSGENRVEREGITLSHPSLFVLAGTMNPEEGELRPQLLDRFGLCVEVRGE
HHHHHHHHCCCCCCCHHHHCCEEEECCCEEEEEECCCCCCCCCCHHHHHHCCCEEEECCC
ADPALRVDLMLRREAFDREPEEFSERYRAEEERLGRTIADAQSLLPSVRIPSHLRGFISE
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
LCRNSNVAGHRADLVIEQAARANAALRGSREVSVEDVTKVAGFALVHRRRDPVPPPEQKP
HHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
QEPERQEEQSRDEQSRQEKPEERGDEPQQPQEGDDRRDGNDDSGNEERSQPENRDAAEQQ
CCCHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCHHHHH
ERPDNEGQDELFSIGQSFRVRSIATPKDRKMRRGSGKRSRSRVSQKQGRYTKSTMPRGNN
HCCCCCCHHHHHHHCHHHEEEECCCCHHHHHHCCCCHHHHHHHHHHHCCCCHHCCCCCCC
DIALDATLRAAAPFQRHRENPNGMAVVLQNEDIREKIREKRLGNLLIFVVDASGSMGARG
CEEEEEHHHHHCCHHHHCCCCCCEEEEEECCHHHHHHHHHHCCCEEEEEEECCCCCCCCC
RMAASKGAVMSLLLDAYQKRDKLAMVSFRKNEAFVNLPVTSSIELAARMLKEMPVGGRTP
CCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEEECCCCCHHHHHHHHHHHCCCCCCCC
FSAGLLKGYEIAQNYLRKEPGGRPLIILVTDGKANRAIGQGKPLDEVFTISEKISREERI
CHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCHHHCE
RFLVVDTEEPGLVTFGLAKKIAGLLDAWYYRIDDLRADTLVSIVKTMMP
EEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; protoporphyrin IX; Mg2+; H2O

Specific reaction: ATP + protoporphyrin IX + Mg2+ + H2O = ADP + phosphate + Mg-protoporphyrin IX + 2 H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]