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The map label for this gene is cbiK [H]

Identifier: 21673228

GI number: 21673228

Start: 403987

End: 404928

Strand: Reverse

Name: cbiK [H]

Synonym: CT0389

Alternate gene names: 21673228

Gene position: 404928-403987 (Counterclockwise)

Preceding gene: 21673229

Following gene: 21673227

Centisome position: 18.79

GC content: 60.19

Gene sequence:

>942_bases
ATGAGTAAGCACAAGAAACGGTCACAGATCAACAAGAAGGCGATTCTGCTTGCCCATTTCGGCACCACCTATCCCTCGGC
ACTGCCGTCGCTGGAGAACATCCGGAGGCAGGTGCGGGCGCGGATTCCCGGCATTGAGGTGCGGCACTGCTTTACCTCGA
ACATGGTGCGCAACATCTGGTCGGCGCGGCGGCGCGATCCGCAACGCTGGCTCGCCGAGGGCGTTGCCGACGAGTTCCTG
AACGTGCAGGGGTTTCTCGGCGCGATCGGTAATTTACAGGACGGCAACTACCGGACGATCATCGTGCAGCCGACCCACAT
GTACCACGGCGAGCAGTTTGAGGATCTGAAATCCTACGTCTCGGCGCTCCAGTCGATCCGCACCATCAAGCGGGTCTGGT
CGCCCTTCGAGAAGGTGGTGCTGTCGCGTCCGGCGCTTGGCACCTGCGGCGTGGAGCACGACTACACCGAGGACATCAAA
GAGGTGGCGGCGCTGTTTGATGATGATGTCGAACGCGCCCGCCAGCTCGACGCGGCGCTGGTTTATGTGGCACACGGCAA
CGACTTCTTCTCGTCGGGTGTGTTCCGCGAAACCGGTGACGTGATGCGCAGTCGCTATCCGGGCGCACAGATTCACATCG
GTATGATCGAGGGGCGGCCCGGCGTGGAGGAGATCGTCGCCGAGGTGACGGGCAAAGGGTGCACGACGGTGCTGTTGCGC
CCCTTCATGATAACGGCGGGTGACCACGCGCACAACGACATTGCCGATGACGATACCGGTTCGTGGAAAGGAGCGTTCGA
GGCGGCGGGATGTCGTGTCGAAATCCGCATGGAGGGACTTGGCTCGGATGATCGTTTCGCCTCGATCTTCGCCAAGCGGA
TTCTTGAAACCGCTGAAGATCATGGTATCGATCTGTTTTCAGCATCCGACAAAATCGATTAA

Upstream 100 bases:

>100_bases
CGGTGGTGTTCATCATCGGCGAACACGCCGTTCCCGAGGGGGCGTGCCCAGATCAGTCCGATGCGTCCGATCCGTCTGAT
CAAAATCACAATGAACAGCA

Downstream 100 bases:

>100_bases
CGCTTTGAACAACCGTTTGCAACCAATGAACAATCAAGGCTCGATCATCAGCGTTTCGCTTGGACCGGGTGATCCCGGGC
TGATTACCGTCAAGGCGCTT

Product: cobalt chelatase CbiK, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MSKHKKRSQINKKAILLAHFGTTYPSALPSLENIRRQVRARIPGIEVRHCFTSNMVRNIWSARRRDPQRWLAEGVADEFL
NVQGFLGAIGNLQDGNYRTIIVQPTHMYHGEQFEDLKSYVSALQSIRTIKRVWSPFEKVVLSRPALGTCGVEHDYTEDIK
EVAALFDDDVERARQLDAALVYVAHGNDFFSSGVFRETGDVMRSRYPGAQIHIGMIEGRPGVEEIVAEVTGKGCTTVLLR
PFMITAGDHAHNDIADDDTGSWKGAFEAAGCRVEIRMEGLGSDDRFASIFAKRILETAEDHGIDLFSASDKID

Sequences:

>Translated_313_residues
MSKHKKRSQINKKAILLAHFGTTYPSALPSLENIRRQVRARIPGIEVRHCFTSNMVRNIWSARRRDPQRWLAEGVADEFL
NVQGFLGAIGNLQDGNYRTIIVQPTHMYHGEQFEDLKSYVSALQSIRTIKRVWSPFEKVVLSRPALGTCGVEHDYTEDIK
EVAALFDDDVERARQLDAALVYVAHGNDFFSSGVFRETGDVMRSRYPGAQIHIGMIEGRPGVEEIVAEVTGKGCTTVLLR
PFMITAGDHAHNDIADDDTGSWKGAFEAAGCRVEIRMEGLGSDDRFASIFAKRILETAEDHGIDLFSASDKID
>Mature_312_residues
SKHKKRSQINKKAILLAHFGTTYPSALPSLENIRRQVRARIPGIEVRHCFTSNMVRNIWSARRRDPQRWLAEGVADEFLN
VQGFLGAIGNLQDGNYRTIIVQPTHMYHGEQFEDLKSYVSALQSIRTIKRVWSPFEKVVLSRPALGTCGVEHDYTEDIKE
VAALFDDDVERARQLDAALVYVAHGNDFFSSGVFRETGDVMRSRYPGAQIHIGMIEGRPGVEEIVAEVTGKGCTTVLLRP
FMITAGDHAHNDIADDDTGSWKGAFEAAGCRVEIRMEGLGSDDRFASIFAKRILETAEDHGIDLFSASDKID

Specific function: Chelates cobalt to the cobalamin precursor as part of the anaerobic pathway to cobalamin biosynthesis [H]

COG id: COG4822

COG function: function code H; Cobalamin biosynthesis protein CbiK, Co2+ chelatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CbiK family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010388 [H]

Pfam domain/function: PF06180 CbiK [H]

EC number: =4.99.1.3 [H]

Molecular weight: Translated: 35009; Mature: 34878

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKHKKRSQINKKAILLAHFGTTYPSALPSLENIRRQVRARIPGIEVRHCFTSNMVRNIW
CCCCHHHHHHCHHEEEEEECCCCCCHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
SARRRDPQRWLAEGVADEFLNVQGFLGAIGNLQDGNYRTIIVQPTHMYHGEQFEDLKSYV
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCHHHCCCHHHHHHHHH
SALQSIRTIKRVWSPFEKVVLSRPALGTCGVEHDYTEDIKEVAALFDDDVERARQLDAAL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEE
VYVAHGNDFFSSGVFRETGDVMRSRYPGAQIHIGMIEGRPGVEEIVAEVTGKGCTTVLLR
EEEECCCHHHHCCCHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHCCCCHHHHHHH
PFMITAGDHAHNDIADDDTGSWKGAFEAAGCRVEIRMEGLGSDDRFASIFAKRILETAED
HHHEECCCCCCCCCCCCCCCCCCCCHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHH
HGIDLFSASDKID
CCCEEECCCCCCC
>Mature Secondary Structure 
SKHKKRSQINKKAILLAHFGTTYPSALPSLENIRRQVRARIPGIEVRHCFTSNMVRNIW
CCCHHHHHHCHHEEEEEECCCCCCHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
SARRRDPQRWLAEGVADEFLNVQGFLGAIGNLQDGNYRTIIVQPTHMYHGEQFEDLKSYV
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCHHHCCCHHHHHHHHH
SALQSIRTIKRVWSPFEKVVLSRPALGTCGVEHDYTEDIKEVAALFDDDVERARQLDAAL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEE
VYVAHGNDFFSSGVFRETGDVMRSRYPGAQIHIGMIEGRPGVEEIVAEVTGKGCTTVLLR
EEEECCCHHHHCCCHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHCCCCHHHHHHH
PFMITAGDHAHNDIADDDTGSWKGAFEAAGCRVEIRMEGLGSDDRFASIFAKRILETAED
HHHEECCCCCCCCCCCCCCCCCCCCHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHH
HGIDLFSASDKID
CCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8501034; 11677609; 9150215; 10451360 [H]