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The map label for this gene is arnC [H]

Identifier: 21673201

GI number: 21673201

Start: 375156

End: 376091

Strand: Reverse

Name: arnC [H]

Synonym: CT0362

Alternate gene names: 21673201

Gene position: 376091-375156 (Counterclockwise)

Preceding gene: 21673202

Following gene: 21673200

Centisome position: 17.45

GC content: 57.91

Gene sequence:

>936_bases
ATGAAACTCTCTGTCGTCATACCGCTCATGAACGAGGCCGAAAGCATTGGCCCGCTCTTCGATGCGCTCGCCTCGGCGCT
TCAGGGCATCGATCACGAAATCATTCTGGTCGATGACGGCTCGACCGACTCGACAGTTGCCGAAATCAAGCGCCTCGCTC
CGGCGAACGCGCGACTGGTGGTGCTCAACAAGAACTACGGCCAGACGGCAGCCATGTCGGCAGGCATCGACGAGGCCCAG
GGCGAGCTGATCGCCACGATGGACGGCGATTTGCAGAACGATCCTGCCGATATTCCAATGATGATCGCCCACCTCGAATC
GAAGGGTCTCGACGTGGTAGCGGGACGGCGCGCAGGGCGGAAGGACGGCATGGTGCTGCGCAAGATTCCGAGCAAGATCG
CCAACGCGATGATCCGGAACCTGACCAACGTGCACATCCGCGATTATGGCTGCACGCTGAAGGTGTTCAAGCGCGACGTG
GCCAAAAACCTCGGTCTGTACGGCGAACTGCACCGCTTCATTCCGGTGCTCGTGCAACTTTACGGCGCGAGGATGGAAGA
GGTCGATGTGCGCCACCACGCGAGGAAATACGGCAAGTCGAAGTACGGCATCGGCAGAACTTTGAGGGTGCTGAGTGACC
TTTTCTTCATGGTTTTTTACCAGAAGTACGCCCACCGACCGATGCACCTGTTCGGCTCGCTCGGCTTCGTCACGCTCTTC
CTCGGCCTCGGCATCAACCTCTACCTGCTCGTACTTAAAATCCTCGGCAACGACATCGGTGGTCGCCCGCTCCTCAGCCT
CGGCGTCATCATGACCTTCATCGGCATCCAGCTGATCACCACCGGCTTCATCGCCGAATTCATCATGCGCACCTACTACG
AGTCGCAGAACAAGAAACCCTACATCATCAGAGAGATCATTGACAAAAGCAAGTAG

Upstream 100 bases:

>100_bases
TGACCACCATCGACCGTCTCGAAAAGCTCGGACCTGTCGAGCGCCTGTATGGCAGGAATGGAATCATGCTCGTCAGAATG
CCGACTCAACCGACTTCCCG

Downstream 100 bases:

>100_bases
CTCCATCAGAAGCAAGGTGCTCAAAACAGTGATCCAGCTCCTGCTCACCGTGGCGGCGCTGGCCATCGTGCTGAACAAGA
CCGATATTGGCCGACTGACT

Product: glycosyl transferase

Products: NA

Alternate protein names: Undecaprenyl-phosphate Ara4FN transferase; Ara4FN transferase [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MKLSVVIPLMNEAESIGPLFDALASALQGIDHEIILVDDGSTDSTVAEIKRLAPANARLVVLNKNYGQTAAMSAGIDEAQ
GELIATMDGDLQNDPADIPMMIAHLESKGLDVVAGRRAGRKDGMVLRKIPSKIANAMIRNLTNVHIRDYGCTLKVFKRDV
AKNLGLYGELHRFIPVLVQLYGARMEEVDVRHHARKYGKSKYGIGRTLRVLSDLFFMVFYQKYAHRPMHLFGSLGFVTLF
LGLGINLYLLVLKILGNDIGGRPLLSLGVIMTFIGIQLITTGFIAEFIMRTYYESQNKKPYIIREIIDKSK

Sequences:

>Translated_311_residues
MKLSVVIPLMNEAESIGPLFDALASALQGIDHEIILVDDGSTDSTVAEIKRLAPANARLVVLNKNYGQTAAMSAGIDEAQ
GELIATMDGDLQNDPADIPMMIAHLESKGLDVVAGRRAGRKDGMVLRKIPSKIANAMIRNLTNVHIRDYGCTLKVFKRDV
AKNLGLYGELHRFIPVLVQLYGARMEEVDVRHHARKYGKSKYGIGRTLRVLSDLFFMVFYQKYAHRPMHLFGSLGFVTLF
LGLGINLYLLVLKILGNDIGGRPLLSLGVIMTFIGIQLITTGFIAEFIMRTYYESQNKKPYIIREIIDKSK
>Mature_311_residues
MKLSVVIPLMNEAESIGPLFDALASALQGIDHEIILVDDGSTDSTVAEIKRLAPANARLVVLNKNYGQTAAMSAGIDEAQ
GELIATMDGDLQNDPADIPMMIAHLESKGLDVVAGRRAGRKDGMVLRKIPSKIANAMIRNLTNVHIRDYGCTLKVFKRDV
AKNLGLYGELHRFIPVLVQLYGARMEEVDVRHHARKYGKSKYGIGRTLRVLSDLFFMVFYQKYAHRPMHLFGSLGFVTLF
LGLGINLYLLVLKILGNDIGGRPLLSLGVIMTFIGIQLITTGFIAEFIMRTYYESQNKKPYIIREIIDKSK

Specific function: Catalyzes the transfer of 4-deoxy-4-formamido-L- arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides [H]

COG id: COG0463

COG function: function code M; Glycosyltransferases involved in cell wall biogenesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family [H]

Homologues:

Organism=Homo sapiens, GI4503363, Length=218, Percent_Identity=29.8165137614679, Blast_Score=68, Evalue=8e-12,
Organism=Escherichia coli, GI1788588, Length=317, Percent_Identity=33.7539432176656, Blast_Score=177, Evalue=6e-46,
Organism=Escherichia coli, GI1788692, Length=313, Percent_Identity=28.4345047923323, Blast_Score=119, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI71999402, Length=215, Percent_Identity=30.2325581395349, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI25146207, Length=218, Percent_Identity=26.605504587156, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6325441, Length=150, Percent_Identity=30.6666666666667, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24585265, Length=233, Percent_Identity=24.0343347639485, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022857
- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: =2.7.8.30 [H]

Molecular weight: Translated: 34566; Mature: 34566

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLSVVIPLMNEAESIGPLFDALASALQGIDHEIILVDDGSTDSTVAEIKRLAPANARLV
CCEEEEEECHHCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCCCEEE
VLNKNYGQTAAMSAGIDEAQGELIATMDGDLQNDPADIPMMIAHLESKGLDVVAGRRAGR
EEECCCCCHHHHHCCCCHHCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCEEEECCCCCC
KDGMVLRKIPSKIANAMIRNLTNVHIRDYGCTLKVFKRDVAKNLGLYGELHRFIPVLVQL
CCCHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
YGARMEEVDVRHHARKYGKSKYGIGRTLRVLSDLFFMVFYQKYAHRPMHLFGSLGFVTLF
HCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
LGLGINLYLLVLKILGNDIGGRPLLSLGVIMTFIGIQLITTGFIAEFIMRTYYESQNKKP
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
YIIREIIDKSK
HHHHHHHCCCC
>Mature Secondary Structure
MKLSVVIPLMNEAESIGPLFDALASALQGIDHEIILVDDGSTDSTVAEIKRLAPANARLV
CCEEEEEECHHCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCCCEEE
VLNKNYGQTAAMSAGIDEAQGELIATMDGDLQNDPADIPMMIAHLESKGLDVVAGRRAGR
EEECCCCCHHHHHCCCCHHCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCEEEECCCCCC
KDGMVLRKIPSKIANAMIRNLTNVHIRDYGCTLKVFKRDVAKNLGLYGELHRFIPVLVQL
CCCHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
YGARMEEVDVRHHARKYGKSKYGIGRTLRVLSDLFFMVFYQKYAHRPMHLFGSLGFVTLF
HCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
LGLGINLYLLVLKILGNDIGGRPLLSLGVIMTFIGIQLITTGFIAEFIMRTYYESQNKKP
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
YIIREIIDKSK
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA