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The map label for this gene is 21673187

Identifier: 21673187

GI number: 21673187

Start: 363640

End: 364950

Strand: Direct

Name: 21673187

Synonym: CT0348

Alternate gene names: NA

Gene position: 363640-364950 (Clockwise)

Preceding gene: 21673186

Following gene: 21673188

Centisome position: 16.87

GC content: 55.68

Gene sequence:

>1311_bases
GTGTGCCGCATGTCGTCGAGAGATTTATCTGAAAAACAGTCTCCGCCAAGGATTATCATCTATTCCGGCAAAGGGGGAAC
GGGCAAGACCACCATTTCGTCCTCTACGGCAGTCGCCCTTGCACGACAAGGCAAACGGGTGCTCATCATGTCCTCCGATC
CGGCTCACTCGCTCTCTGATGTGTTCGGCGTGCAGATTGGCCGCAACGAGCCGCTCAAGATCGAAAAGAACCTGTACGGT
CTCGAAGTCGATACCATCTACGAGCTGAAGAAAAACATGTCGGGCTTCCAGAAGTTCGTCTCTTCGTCGTACAAGAATCA
GGGCATTGACAGCGGCATGGCTTCGGAGCTGACCACGCAGCCAGGTCTTGACGAAATCTTCGCGCTTTCCCGTCTGCTCG
ACGAATCGCAGTCCGGCAAGTGGGACACTATCGTGCTCGATACCTCGCCGACCGGCAACACGCTTCGACTGCTCGCCTAC
CCGGAGATCATCATCGGCGGCAACATGGGCAAGCAGTTCTTCAAGCTCTACAAGAGCATGTCTTCGCTGGCGCGTCCTCT
CTCGGGCAACAATATTCCCGACGACGACTTCTTCAACGAGGTCAACGTGCTGCTCAAGCAGATGGAGGACATCAACGAGT
TCATTCTCAGCCCGGAGGTCACCTTCCGGCTGGTGCTGAACCCGGAGAAACTCTCGATTCTCGAAACCAAGCGCGCCTAT
ACTTTCGTGCACCTCTACGGTATCAATATCGACGGCATCGTCATCAACAAGATTCTGCCGACCTCGCGAACCGTGGGCGA
GTACTTCGAGTTCTGGGCCGATCTGCACAGCAAGTACCTGATGGAGATCGACAACTCCTTCTATCCGACGCCGGTCTTCC
GCTGCCACCTGCAACGCACCGAGCCGATCGGCCCCGACGCTCTCTACGACATCAGCCAGATCGTCTTCGGCGAAGAGGCT
CCCGACAAGACCTTCTATTCGGGCAAGAACTTCTGGATCGAGAGCAAAAAGAATCAGGCGACCTCTGACAACCGCGAGGT
GCTCTGCATCCGGATTCCGTTCCTCAAGGACGCCGCAGATGTCTCGGTCGAGCGTATGGGTACCGACATCATCGTCACGG
TTGACCGCGCCCAGCGCAATATCACCTTGCCAAGGGCGCTCTACAGCCTCGACATGGATCGCTTCGTCCGTGAAGACAAC
ATACTGAGGGTGATCTTCAAGGAGGTTAAGGTTGACAAGGAGGAGATGGAGCTGAACGTCAACAAGAACGTTCTTGACAA
GTTGCGCTCCATGCGCCGCCTGAAAATCTGA

Upstream 100 bases:

>100_bases
TATTCCAAAATGATTTAGCGATCTTTTGAAAATGTTGCTGTAAAAGTGCTAACTTCACAGTTCGTTTTATCGGGATCATT
TTTCAGGCTGTATCAAAGGA

Downstream 100 bases:

>100_bases
CAGCTGTGCCACCGGATTCCGCGCTTCTTGCCATTCCCGATGGCGCGGCCCTGACTGGTGGCAGGTTGATTTCCGTACCA
CAGTTTGTGTTGTATCGCCT

Product: ArsA ATPase family protein

Products: NA

Alternate protein names: Arsenical resistance ATPase; Arsenite-translocating ATPase; Arsenite-transporting ATPase [H]

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MCRMSSRDLSEKQSPPRIIIYSGKGGTGKTTISSSTAVALARQGKRVLIMSSDPAHSLSDVFGVQIGRNEPLKIEKNLYG
LEVDTIYELKKNMSGFQKFVSSSYKNQGIDSGMASELTTQPGLDEIFALSRLLDESQSGKWDTIVLDTSPTGNTLRLLAY
PEIIIGGNMGKQFFKLYKSMSSLARPLSGNNIPDDDFFNEVNVLLKQMEDINEFILSPEVTFRLVLNPEKLSILETKRAY
TFVHLYGINIDGIVINKILPTSRTVGEYFEFWADLHSKYLMEIDNSFYPTPVFRCHLQRTEPIGPDALYDISQIVFGEEA
PDKTFYSGKNFWIESKKNQATSDNREVLCIRIPFLKDAADVSVERMGTDIIVTVDRAQRNITLPRALYSLDMDRFVREDN
ILRVIFKEVKVDKEEMELNVNKNVLDKLRSMRRLKI

Sequences:

>Translated_436_residues
MCRMSSRDLSEKQSPPRIIIYSGKGGTGKTTISSSTAVALARQGKRVLIMSSDPAHSLSDVFGVQIGRNEPLKIEKNLYG
LEVDTIYELKKNMSGFQKFVSSSYKNQGIDSGMASELTTQPGLDEIFALSRLLDESQSGKWDTIVLDTSPTGNTLRLLAY
PEIIIGGNMGKQFFKLYKSMSSLARPLSGNNIPDDDFFNEVNVLLKQMEDINEFILSPEVTFRLVLNPEKLSILETKRAY
TFVHLYGINIDGIVINKILPTSRTVGEYFEFWADLHSKYLMEIDNSFYPTPVFRCHLQRTEPIGPDALYDISQIVFGEEA
PDKTFYSGKNFWIESKKNQATSDNREVLCIRIPFLKDAADVSVERMGTDIIVTVDRAQRNITLPRALYSLDMDRFVREDN
ILRVIFKEVKVDKEEMELNVNKNVLDKLRSMRRLKI
>Mature_436_residues
MCRMSSRDLSEKQSPPRIIIYSGKGGTGKTTISSSTAVALARQGKRVLIMSSDPAHSLSDVFGVQIGRNEPLKIEKNLYG
LEVDTIYELKKNMSGFQKFVSSSYKNQGIDSGMASELTTQPGLDEIFALSRLLDESQSGKWDTIVLDTSPTGNTLRLLAY
PEIIIGGNMGKQFFKLYKSMSSLARPLSGNNIPDDDFFNEVNVLLKQMEDINEFILSPEVTFRLVLNPEKLSILETKRAY
TFVHLYGINIDGIVINKILPTSRTVGEYFEFWADLHSKYLMEIDNSFYPTPVFRCHLQRTEPIGPDALYDISQIVFGEEA
PDKTFYSGKNFWIESKKNQATSDNREVLCIRIPFLKDAADVSVERMGTDIIVTVDRAQRNITLPRALYSLDMDRFVREDN
ILRVIFKEVKVDKEEMELNVNKNVLDKLRSMRRLKI

Specific function: Anion-transporting ATPase. Catalyzes the extrusion of arsenite [H]

COG id: COG0003

COG function: function code P; Oxyanion-translocating ATPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arsA ATPase family [H]

Homologues:

Organism=Homo sapiens, GI50428938, Length=300, Percent_Identity=25.3333333333333, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17557003, Length=313, Percent_Identity=25.8785942492013, Blast_Score=92, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6320103, Length=313, Percent_Identity=26.1980830670927, Blast_Score=90, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24586297, Length=293, Percent_Identity=26.6211604095563, Blast_Score=96, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003348 [H]

Pfam domain/function: NA

EC number: =3.6.3.16 [H]

Molecular weight: Translated: 49524; Mature: 49524

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCRMSSRDLSEKQSPPRIIIYSGKGGTGKTTISSSTAVALARQGKRVLIMSSDPAHSLSD
CCCCCCCCCHHCCCCCEEEEEECCCCCCCEEECCCHHHHHHHCCCEEEEEECCCCHHHHH
VFGVQIGRNEPLKIEKNLYGLEVDTIYELKKNMSGFQKFVSSSYKNQGIDSGMASELTTQ
HHHEEECCCCCEEEECCEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCC
PGLDEIFALSRLLDESQSGKWDTIVLDTSPTGNTLRLLAYPEIIIGGNMGKQFFKLYKSM
CCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEEEEECCEEEEECCCCHHHHHHHHHH
SSLARPLSGNNIPDDDFFNEVNVLLKQMEDINEFILSPEVTFRLVLNPEKLSILETKRAY
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHEECCCEE
TFVHLYGINIDGIVINKILPTSRTVGEYFEFWADLHSKYLMEIDNSFYPTPVFRCHLQRT
EEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCC
EPIGPDALYDISQIVFGEEAPDKTFYSGKNFWIESKKNQATSDNREVLCIRIPFLKDAAD
CCCCCHHHHHHHHHHCCCCCCCCCEECCCCEEEECCCCCCCCCCCEEEEEECCCCCCCHH
VSVERMGTDIIVTVDRAQRNITLPRALYSLDMDRFVREDNILRVIFKEVKVDKEEMELNV
CHHHHCCCEEEEEEECCCCCCCHHHHHHHHCHHHHHHHCCHHHHHHHHHHCCHHHHEECC
NKNVLDKLRSMRRLKI
CHHHHHHHHHHHHCCC
>Mature Secondary Structure
MCRMSSRDLSEKQSPPRIIIYSGKGGTGKTTISSSTAVALARQGKRVLIMSSDPAHSLSD
CCCCCCCCCHHCCCCCEEEEEECCCCCCCEEECCCHHHHHHHCCCEEEEEECCCCHHHHH
VFGVQIGRNEPLKIEKNLYGLEVDTIYELKKNMSGFQKFVSSSYKNQGIDSGMASELTTQ
HHHEEECCCCCEEEECCEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCC
PGLDEIFALSRLLDESQSGKWDTIVLDTSPTGNTLRLLAYPEIIIGGNMGKQFFKLYKSM
CCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEEEEECCEEEEECCCCHHHHHHHHHH
SSLARPLSGNNIPDDDFFNEVNVLLKQMEDINEFILSPEVTFRLVLNPEKLSILETKRAY
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHEECCCEE
TFVHLYGINIDGIVINKILPTSRTVGEYFEFWADLHSKYLMEIDNSFYPTPVFRCHLQRT
EEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCC
EPIGPDALYDISQIVFGEEAPDKTFYSGKNFWIESKKNQATSDNREVLCIRIPFLKDAAD
CCCCCHHHHHHHHHHCCCCCCCCCEECCCCEEEECCCCCCCCCCCEEEEEECCCCCCCHH
VSVERMGTDIIVTVDRAQRNITLPRALYSLDMDRFVREDNILRVIFKEVKVDKEEMELNV
CHHHHCCCEEEEEEECCCCCCCHHHHHHHHCHHHHHHHCCHHHHHHHHHHCCHHHHEECC
NKNVLDKLRSMRRLKI
CHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]