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The map label for this gene is glmU [H]

Identifier: 21673090

GI number: 21673090

Start: 261019

End: 261762

Strand: Reverse

Name: glmU [H]

Synonym: CT0251

Alternate gene names: 21673090

Gene position: 261762-261019 (Counterclockwise)

Preceding gene: 21673091

Following gene: 21673077

Centisome position: 12.15

GC content: 56.05

Gene sequence:

>744_bases
ATGAGCCTGGCAATCGTCATCATGGCCGCCGGTAAAGGCACGCGAATGAAATCGGCTCTCCCGAAGGTACTGCACGAGGC
CAATGGCAAACCGCTCGTGGCGTATGTCATCGAAAAATCGCAGGCGCTCGATCCCGACAAGATCGTGCTCATCATCGGCC
ATCAGGCCGAGCTGGTTCGGGCTGCAACCGCCGGTTTTCCGTTCGATTATGCCTTGCAGGAGCCTCAACTCGGCACCGGC
CACGCCATCATGCAGGCTGAACCGTTCCTGAAAGATTTCAGCGGAGAGATTATCATCCTCTCGGGAGACGCGCCGCTCTT
CACCGGGCGCACACTCAGAGAGCTGATCGACTTCCATCGTTCGCGGCAAGCTGTCGCCACGGTACTGACCGCCGAGATGG
ACGACCCAACAGGATACGGGCGGATCATCAGAAGTGATGCGGGCGAAGAGGTGCTCAGAATCGTCGAGCAGAAAGATGCC
ACGGAAGAAGAAAAAGCGGTAACTGAAATCAACTCCGGCGTTTACGTCTTCAACGCCAACGAGCTGTTTTCCGCCCTGCA
CGGCATCACCAACAAAAACGCCCAAGGGGAGTACTATCTCACCGATGTGTTCGGTATCTGCTTTGGAAAAGGCAAAAAAG
TGTGCGCCTTCAAGGTAGCCGATGCCAACGAAATCCGCGGCATCAACACCCCCGAACAACTCAGGGAAGCAGAACTGCTC
CTGCAAGGCGAAAAGTATTGCTGA

Upstream 100 bases:

>100_bases
TCATCGTTGACCGGATGAACAATCCGAAGCGACGCCACCGGGTAGGTTCCGAAGACGAATATCTTGGCTGAAGCCATCTC
AACCCCTCAGCAAGAACTTT

Downstream 100 bases:

>100_bases
AAAAATCGGTGGGATTGGTCATATCCGACTGATCTGGCCAATCCGGGCACAGCCCCACCACCCAATCTCCAGTGTTCCAA
GCCATATCGGTAATCCGCTA

Product: UDP-N-acetylglucosamine pyrophosphorylase, putative

Products: NA

Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MSLAIVIMAAGKGTRMKSALPKVLHEANGKPLVAYVIEKSQALDPDKIVLIIGHQAELVRAATAGFPFDYALQEPQLGTG
HAIMQAEPFLKDFSGEIIILSGDAPLFTGRTLRELIDFHRSRQAVATVLTAEMDDPTGYGRIIRSDAGEEVLRIVEQKDA
TEEEKAVTEINSGVYVFNANELFSALHGITNKNAQGEYYLTDVFGICFGKGKKVCAFKVADANEIRGINTPEQLREAELL
LQGEKYC

Sequences:

>Translated_247_residues
MSLAIVIMAAGKGTRMKSALPKVLHEANGKPLVAYVIEKSQALDPDKIVLIIGHQAELVRAATAGFPFDYALQEPQLGTG
HAIMQAEPFLKDFSGEIIILSGDAPLFTGRTLRELIDFHRSRQAVATVLTAEMDDPTGYGRIIRSDAGEEVLRIVEQKDA
TEEEKAVTEINSGVYVFNANELFSALHGITNKNAQGEYYLTDVFGICFGKGKKVCAFKVADANEIRGINTPEQLREAELL
LQGEKYC
>Mature_246_residues
SLAIVIMAAGKGTRMKSALPKVLHEANGKPLVAYVIEKSQALDPDKIVLIIGHQAELVRAATAGFPFDYALQEPQLGTGH
AIMQAEPFLKDFSGEIIILSGDAPLFTGRTLRELIDFHRSRQAVATVLTAEMDDPTGYGRIIRSDAGEEVLRIVEQKDAT
EEEKAVTEINSGVYVFNANELFSALHGITNKNAQGEYYLTDVFGICFGKGKKVCAFKVADANEIRGINTPEQLREAELLL
QGEKYC

Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-GlcNAc. Responsible for the acetylation of Glc-N-1-P to give GlcNAc-1-P and for the uridyl transfer from UTP to GlcNAc-1-P which produces UDP-GlcNAc [H]

COG id: COG1207

COG function: function code M; N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1790168, Length=244, Percent_Identity=41.3934426229508, Blast_Score=191, Evalue=3e-50,
Organism=Saccharomyces cerevisiae, GI6320148, Length=184, Percent_Identity=26.6304347826087, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005882
- InterPro:   IPR018357
- InterPro:   IPR005835
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.23; =2.3.1.157 [H]

Molecular weight: Translated: 26986; Mature: 26855

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLAIVIMAAGKGTRMKSALPKVLHEANGKPLVAYVIEKSQALDPDKIVLIIGHQAELVR
CCEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCEEEEECCCHHHHH
AATAGFPFDYALQEPQLGTGHAIMQAEPFLKDFSGEIIILSGDAPLFTGRTLRELIDFHR
HHHCCCCCCCCCCCCCCCCCCEEEECCHHHHHCCCCEEEEECCCCEECCHHHHHHHHHHH
SRQAVATVLTAEMDDPTGYGRIIRSDAGEEVLRIVEQKDATEEEKAVTEINSGVYVFNAN
HHHHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEHH
ELFSALHGITNKNAQGEYYLTDVFGICFGKGKKVCAFKVADANEIRGINTPEQLREAELL
HHHHHHHCCCCCCCCCCEEEHHHHHHHHCCCCEEEEEEECCHHHCCCCCCHHHHHHHHHH
LQGEKYC
HCCCCCC
>Mature Secondary Structure 
SLAIVIMAAGKGTRMKSALPKVLHEANGKPLVAYVIEKSQALDPDKIVLIIGHQAELVR
CEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCEEEEECCCHHHHH
AATAGFPFDYALQEPQLGTGHAIMQAEPFLKDFSGEIIILSGDAPLFTGRTLRELIDFHR
HHHCCCCCCCCCCCCCCCCCCEEEECCHHHHHCCCCEEEEECCCCEECCHHHHHHHHHHH
SRQAVATVLTAEMDDPTGYGRIIRSDAGEEVLRIVEQKDATEEEKAVTEINSGVYVFNAN
HHHHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEHH
ELFSALHGITNKNAQGEYYLTDVFGICFGKGKKVCAFKVADANEIRGINTPEQLREAELL
HHHHHHHCCCCCCCCCCEEEHHHHHHHHCCCCEEEEEEECCHHHCCCCCCHHHHHHHHHH
LQGEKYC
HCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA