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The map label for this gene is yaeL [C]

Identifier: 21672965

GI number: 21672965

Start: 117911

End: 119272

Strand: Reverse

Name: yaeL [C]

Synonym: CT0124

Alternate gene names: 21672965

Gene position: 119272-117911 (Counterclockwise)

Preceding gene: 21672966

Following gene: 21672964

Centisome position: 5.53

GC content: 56.98

Gene sequence:

>1362_bases
ATGGAGCTACTGAACACGATATTCTTCTTCGTCATCGCCATCTTCATCCTCGTCACGGCCCACGAATTCGGCCACTTTAT
CACGGCGAGGATGTTCGGCATGCGGGTCGACCGGTTTTTCATCGGTTTCGATTTCTGGGGCATCAAGCTGTGGCAGAAAA
AGATCGGAGAAACCGAATACGGTATCGGCGCCTTCCCGATTGGCGGCTACGTCAAGATCGCCGGCATGATCGACGAAAGC
ATGGACACCGACCATGTATCACAAGAGGTCCAACCGTGGGAGTTCAGGGCCAAACCGGTCTGGCAGCGCCTCATCGTGCT
GGCTGGCGGCGTGGCGATGAACATGGTGCTGGCCGCCGTTATCTTCATCGGTATCACCAGCATTTTCGGAGAATCACGTA
CTCCCATAACCACGCCAGCCTTTATCGAACCGAAGTCCGTATTCTCTTCGATGGGCATGCAAAGCGGCGACCATCTGGTA
GCGATCAACGGCCAGAAACTGCACTACTGGGAAGAGGCCCTCGATCCCGAGCGCCTGGCATCGGGAAAACTGCAATACAC
CATTGAGCGGAACGGAGAGGAGTTGACACTCACGGCGCCGAAAGACATTATCTCCCGGATCAACGGAAACCAGTCGATCG
GCATCAGGCCAACCGTGCCTCCAGTCATAGACCAGGTGCTGCCCGGCGATCCGGCGGCTAAAGCCGGTATCATGCCGGGC
GGCCTCATCACTGCCATCAATGGCTCGCCAGTGGCCGACTGGAGCGAGGTGGTCAATATCATCTCCGCGAACGCAGGCAA
AAAGCTCACCGTCACCTGGATGCATCTGAAAAACTCGACTGGCGAACCGCTGACCGCCGCTCTCATCCGCAAAAAGGGGC
AAACCATTACCACCGAGGTGACGCCGAACAACTCAGGCAAAATCGGCATTTCGCTCAAGCAGACCATCGAGACCGAACGC
ATCAAGCTTTCGCTTCCGCAGGCCATCGCCAGCGGCCTGAACCAGACCTGGAAAACCACCGTGCTGACCGTCCAGGGATT
CGGTAAAATTTTCAGCGGCAAGGAGGATTTCCGCAAGTCGGTCGGCGGCCCGATCAAGATCGCCCGCATCGCCAACCAGA
GCGCCGAGCAGGGACCAATCAGCTTCATGTACTTTGTGGCCGTGCTCTCAATCTCGCTGGCGATCATCAATATTCTGCCC
ATCCCTGCGCTCGACGGCGGGCAGTTCGTGCTCAACGCCATCGAGGGCATCATGGGCAGGGAGATTCCGTTCGAGGTCAA
AATGCGTATCCAGCAGGTCGGCATGACTCTTCTGCTGATGCTCTTCGCCTACTTCATGATAAACGACCTCCTGAACCCCT
GA

Upstream 100 bases:

>100_bases
GTACCTTCAGGCAGACAAATGGGCCCGCGAAACCGCACGGCAGCTTATCGGATAATTCCGGGCTAAACATCACGAAACAA
CCGAACGACCTGCATTTGAC

Downstream 100 bases:

>100_bases
TTCCGGCAGCGGCGAGCAACCATGTTTGACAAGCTTCAGTCCATCAAGGATAAATTCCAGACCATCGAGCAGCAGCTTTC
CGATCCGGAGGTGGTCGCCG

Product: membrane-associated zinc metalloprotease, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MELLNTIFFFVIAIFILVTAHEFGHFITARMFGMRVDRFFIGFDFWGIKLWQKKIGETEYGIGAFPIGGYVKIAGMIDES
MDTDHVSQEVQPWEFRAKPVWQRLIVLAGGVAMNMVLAAVIFIGITSIFGESRTPITTPAFIEPKSVFSSMGMQSGDHLV
AINGQKLHYWEEALDPERLASGKLQYTIERNGEELTLTAPKDIISRINGNQSIGIRPTVPPVIDQVLPGDPAAKAGIMPG
GLITAINGSPVADWSEVVNIISANAGKKLTVTWMHLKNSTGEPLTAALIRKKGQTITTEVTPNNSGKIGISLKQTIETER
IKLSLPQAIASGLNQTWKTTVLTVQGFGKIFSGKEDFRKSVGGPIKIARIANQSAEQGPISFMYFVAVLSISLAIINILP
IPALDGGQFVLNAIEGIMGREIPFEVKMRIQQVGMTLLLMLFAYFMINDLLNP

Sequences:

>Translated_453_residues
MELLNTIFFFVIAIFILVTAHEFGHFITARMFGMRVDRFFIGFDFWGIKLWQKKIGETEYGIGAFPIGGYVKIAGMIDES
MDTDHVSQEVQPWEFRAKPVWQRLIVLAGGVAMNMVLAAVIFIGITSIFGESRTPITTPAFIEPKSVFSSMGMQSGDHLV
AINGQKLHYWEEALDPERLASGKLQYTIERNGEELTLTAPKDIISRINGNQSIGIRPTVPPVIDQVLPGDPAAKAGIMPG
GLITAINGSPVADWSEVVNIISANAGKKLTVTWMHLKNSTGEPLTAALIRKKGQTITTEVTPNNSGKIGISLKQTIETER
IKLSLPQAIASGLNQTWKTTVLTVQGFGKIFSGKEDFRKSVGGPIKIARIANQSAEQGPISFMYFVAVLSISLAIINILP
IPALDGGQFVLNAIEGIMGREIPFEVKMRIQQVGMTLLLMLFAYFMINDLLNP
>Mature_453_residues
MELLNTIFFFVIAIFILVTAHEFGHFITARMFGMRVDRFFIGFDFWGIKLWQKKIGETEYGIGAFPIGGYVKIAGMIDES
MDTDHVSQEVQPWEFRAKPVWQRLIVLAGGVAMNMVLAAVIFIGITSIFGESRTPITTPAFIEPKSVFSSMGMQSGDHLV
AINGQKLHYWEEALDPERLASGKLQYTIERNGEELTLTAPKDIISRINGNQSIGIRPTVPPVIDQVLPGDPAAKAGIMPG
GLITAINGSPVADWSEVVNIISANAGKKLTVTWMHLKNSTGEPLTAALIRKKGQTITTEVTPNNSGKIGISLKQTIETER
IKLSLPQAIASGLNQTWKTTVLTVQGFGKIFSGKEDFRKSVGGPIKIARIANQSAEQGPISFMYFVAVLSISLAIINILP
IPALDGGQFVLNAIEGIMGREIPFEVKMRIQQVGMTLLLMLFAYFMINDLLNP

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=478, Percent_Identity=31.1715481171548, Blast_Score=174, Evalue=1e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915 [H]

Pfam domain/function: PF00595 PDZ; PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 49639; Mature: 49639

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELLNTIFFFVIAIFILVTAHEFGHFITARMFGMRVDRFFIGFDFWGIKLWQKKIGETEY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEHHHHHHHHHHCCCCCC
GIGAFPIGGYVKIAGMIDESMDTDHVSQEVQPWEFRAKPVWQRLIVLAGGVAMNMVLAAV
CCCEECCCCEEEEEEHHCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHH
IFIGITSIFGESRTPITTPAFIEPKSVFSSMGMQSGDHLVAINGQKLHYWEEALDPERLA
HHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEEECCCEEEHHHHHCCHHHHC
SGKLQYTIERNGEELTLTAPKDIISRINGNQSIGIRPTVPPVIDQVLPGDPAAKAGIMPG
CCCEEEEEECCCCEEEEECCHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCC
GLITAINGSPVADWSEVVNIISANAGKKLTVTWMHLKNSTGEPLTAALIRKKGQTITTEV
CEEEEECCCCCCCHHHHHHHHHCCCCCEEEEEEEEECCCCCCHHHHHHHHHCCCEEEEEE
TPNNSGKIGISLKQTIETERIKLSLPQAIASGLNQTWKTTVLTVQGFGKIFSGKEDFRKS
CCCCCCEEEEEEHHHHCHHHEEEECHHHHHHCCCCCCEEEEEEEECCHHHHCCHHHHHHH
VGGPIKIARIANQSAEQGPISFMYFVAVLSISLAIINILPIPALDGGQFVLNAIEGIMGR
CCCCEEEEEHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCC
EIPFEVKMRIQQVGMTLLLMLFAYFMINDLLNP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MELLNTIFFFVIAIFILVTAHEFGHFITARMFGMRVDRFFIGFDFWGIKLWQKKIGETEY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEHHHHHHHHHHCCCCCC
GIGAFPIGGYVKIAGMIDESMDTDHVSQEVQPWEFRAKPVWQRLIVLAGGVAMNMVLAAV
CCCEECCCCEEEEEEHHCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHH
IFIGITSIFGESRTPITTPAFIEPKSVFSSMGMQSGDHLVAINGQKLHYWEEALDPERLA
HHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEEECCCEEEHHHHHCCHHHHC
SGKLQYTIERNGEELTLTAPKDIISRINGNQSIGIRPTVPPVIDQVLPGDPAAKAGIMPG
CCCEEEEEECCCCEEEEECCHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCC
GLITAINGSPVADWSEVVNIISANAGKKLTVTWMHLKNSTGEPLTAALIRKKGQTITTEV
CEEEEECCCCCCCHHHHHHHHHCCCCCEEEEEEEEECCCCCCHHHHHHHHHCCCEEEEEE
TPNNSGKIGISLKQTIETERIKLSLPQAIASGLNQTWKTTVLTVQGFGKIFSGKEDFRKS
CCCCCCEEEEEEHHHHCHHHEEEECHHHHHHCCCCCCEEEEEEEECCHHHHCCHHHHHHH
VGGPIKIARIANQSAEQGPISFMYFVAVLSISLAIINILPIPALDGGQFVLNAIEGIMGR
CCCCEEEEEHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCC
EIPFEVKMRIQQVGMTLLLMLFAYFMINDLLNP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]