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The map label for this gene is paaK [H]

Identifier: 21672953

GI number: 21672953

Start: 106811

End: 108130

Strand: Reverse

Name: paaK [H]

Synonym: CT0112

Alternate gene names: 21672953

Gene position: 108130-106811 (Counterclockwise)

Preceding gene: 21672954

Following gene: 21672952

Centisome position: 5.02

GC content: 60.68

Gene sequence:

>1320_bases
ATGATCTGGAACGAGCATCACGAATGCATGGGGCGCGACCAGCTGGCATCGCTGCAGGGCGAACGCCTTCGCCAAATGGT
CGAACGGATCTACTACAACGTGCCATTCTACCGCAACAAGCTGCAGGAGATGGGCATCGAGCCGGGAGACATCCGCTCGA
TCGACGACCTGAAAAAGCTGCCCTTCACCACCAAGCAGGACCTGCGCGACAACTACCCGTTCGGGCTGTTTGCTGTGCCT
CAGCAGGATATCGTGCGATTCCATGCCTCAAGCGGCACCACCGGCAAGTCGACCGTGGTCGGGTACACCCATAACGATAT
CATGATGTGGTCCGAGGTGGTCGCCCGTTCGCTCACGATGGCCGGGGTCACGAAACACGACATCATCCAGGTCGCCTACG
GCTACGGACTCTTCACCGGCGGTCTTGGCCTGCACTACGGCGCCGAGAAAATCGGCGCGTCGGTCATCCCGATCTCCGGC
GGCAACACCAAAAAGCAGCTCCAGCTGCTGGAGGATTTCGGTTCGACCGCCATCGCCTGCACCCCCTCCTACGCGGCATA
CCTCGGCGAGGCCATCATGGAGGAGAAGCTCGACCGCTCGAAGATCAAGCTGAAAGCGGGTATCTTCGGCGCGGAGCCGT
GGACGGAGGAGATGCGCTCGCAGATCCAGCAGCTCCTCGGAATCAAGGCGTACGACATCTACGGCCTCTCCGAAGTGATC
GGACCGGGCGTCTCGATGGAGTGCAGCATCCAGCACGGGATGCACGTCTTCGAGGATCACTTCATTCCAGAAATCATCAA
TCCTGAAACCGGCGAGGTGCTGCCGTACGGCGAGCTGGGCGAACTGGTCTTCACCGCGGTCACCAAGGAGGCCTTGCCGC
TCCTGCGCTACCGCACGCGCGACCTCACCCGCCTGCACGTCGAGCGCTGCGACTGCGGTCGCACGCTGGTGCGCATGGAG
AAGTGCGTCGGGCGTTCGGACGACATGCTCATCATTCGCGGCGTGAACGTCTTCCCGTCGCAGGTCGAATCGGTGCTGCT
CGAAATGAGCGAAACCAAACCGCACTACCTGCTCGTGGTCGATCGCCAGAACAACCTCGACACCCTCGAAATCCAGGTCG
AAGTCGAAGACCAGTTCTTCTCCGACGAAGTCAAAGAGCTCGAAGGTCTCCGCAAACGCATCAGCGGCAACCTGACCAGC
ATCCTCGGCCTGCATGCAAATGTCAGGCTGGTCGAACCTGGCACCATCGAACGCAGCCAGGGCAAGGCACAGCGCGTCGT
GGACAAACGCAAACTCAACGAACACAAGGAGACGCCATGA

Upstream 100 bases:

>100_bases
TCGAGGCGCTTTTCAGCACCAAGGGGCAGGAGGTCGTCGACATCAATATCAGGGCGTTCCGCAAGGGACTGCAGCTTTCC
AACACCGAACTTCACCATCC

Downstream 100 bases:

>100_bases
TCATCAAACAACTCTCGGTGTTTCTCGAAAACCGCGCCGGAAGACTGACCGAGCTGACCGGCATCCTGGCCGACAACGAC
ATCAACATCTCGGCATTCAG

Product: phenylacetyl-coenzyme A ligase

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MIWNEHHECMGRDQLASLQGERLRQMVERIYYNVPFYRNKLQEMGIEPGDIRSIDDLKKLPFTTKQDLRDNYPFGLFAVP
QQDIVRFHASSGTTGKSTVVGYTHNDIMMWSEVVARSLTMAGVTKHDIIQVAYGYGLFTGGLGLHYGAEKIGASVIPISG
GNTKKQLQLLEDFGSTAIACTPSYAAYLGEAIMEEKLDRSKIKLKAGIFGAEPWTEEMRSQIQQLLGIKAYDIYGLSEVI
GPGVSMECSIQHGMHVFEDHFIPEIINPETGEVLPYGELGELVFTAVTKEALPLLRYRTRDLTRLHVERCDCGRTLVRME
KCVGRSDDMLIIRGVNVFPSQVESVLLEMSETKPHYLLVVDRQNNLDTLEIQVEVEDQFFSDEVKELEGLRKRISGNLTS
ILGLHANVRLVEPGTIERSQGKAQRVVDKRKLNEHKETP

Sequences:

>Translated_439_residues
MIWNEHHECMGRDQLASLQGERLRQMVERIYYNVPFYRNKLQEMGIEPGDIRSIDDLKKLPFTTKQDLRDNYPFGLFAVP
QQDIVRFHASSGTTGKSTVVGYTHNDIMMWSEVVARSLTMAGVTKHDIIQVAYGYGLFTGGLGLHYGAEKIGASVIPISG
GNTKKQLQLLEDFGSTAIACTPSYAAYLGEAIMEEKLDRSKIKLKAGIFGAEPWTEEMRSQIQQLLGIKAYDIYGLSEVI
GPGVSMECSIQHGMHVFEDHFIPEIINPETGEVLPYGELGELVFTAVTKEALPLLRYRTRDLTRLHVERCDCGRTLVRME
KCVGRSDDMLIIRGVNVFPSQVESVLLEMSETKPHYLLVVDRQNNLDTLEIQVEVEDQFFSDEVKELEGLRKRISGNLTS
ILGLHANVRLVEPGTIERSQGKAQRVVDKRKLNEHKETP
>Mature_439_residues
MIWNEHHECMGRDQLASLQGERLRQMVERIYYNVPFYRNKLQEMGIEPGDIRSIDDLKKLPFTTKQDLRDNYPFGLFAVP
QQDIVRFHASSGTTGKSTVVGYTHNDIMMWSEVVARSLTMAGVTKHDIIQVAYGYGLFTGGLGLHYGAEKIGASVIPISG
GNTKKQLQLLEDFGSTAIACTPSYAAYLGEAIMEEKLDRSKIKLKAGIFGAEPWTEEMRSQIQQLLGIKAYDIYGLSEVI
GPGVSMECSIQHGMHVFEDHFIPEIINPETGEVLPYGELGELVFTAVTKEALPLLRYRTRDLTRLHVERCDCGRTLVRME
KCVGRSDDMLIIRGVNVFPSQVESVLLEMSETKPHYLLVVDRQNNLDTLEIQVEVEDQFFSDEVKELEGLRKRISGNLTS
ILGLHANVRLVEPGTIERSQGKAQRVVDKRKLNEHKETP

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=428, Percent_Identity=53.0373831775701, Blast_Score=445, Evalue=1e-126,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 49505; Mature: 49505

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIWNEHHECMGRDQLASLQGERLRQMVERIYYNVPFYRNKLQEMGIEPGDIRSIDDLKKL
CCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCHHHHHHC
PFTTKQDLRDNYPFGLFAVPQQDIVRFHASSGTTGKSTVVGYTHNDIMMWSEVVARSLTM
CCCCHHHHHCCCCEEEEECCHHHHHEEECCCCCCCCCEEEEEECCCHHHHHHHHHHHHHH
AGVTKHDIIQVAYGYGLFTGGLGLHYGAEKIGASVIPISGGNTKKQLQLLEDFGSTAIAC
HCCCHHHHHHHHHHCHHHCCCCCCCCCHHHHCCEEEEECCCCHHHHHHHHHHCCCCEEEE
TPSYAAYLGEAIMEEKLDRSKIKLKAGIFGAEPWTEEMRSQIQQLLGIKAYDIYGLSEVI
CCHHHHHHHHHHHHHHHCHHHEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEECCHHHHH
GPGVSMECSIQHGMHVFEDHFIPEIINPETGEVLPYGELGELVFTAVTKEALPLLRYRTR
CCCCCEEEEHHHCHHHHHHCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
DLTRLHVERCDCGRTLVRMEKCVGRSDDMLIIRGVNVFPSQVESVLLEMSETKPHYLLVV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEE
DRQNNLDTLEIQVEVEDQFFSDEVKELEGLRKRISGNLTSILGLHANVRLVEPGTIERSQ
ECCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCEEEECCCCCCCCC
GKAQRVVDKRKLNEHKETP
CHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIWNEHHECMGRDQLASLQGERLRQMVERIYYNVPFYRNKLQEMGIEPGDIRSIDDLKKL
CCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCHHHHHHC
PFTTKQDLRDNYPFGLFAVPQQDIVRFHASSGTTGKSTVVGYTHNDIMMWSEVVARSLTM
CCCCHHHHHCCCCEEEEECCHHHHHEEECCCCCCCCCEEEEEECCCHHHHHHHHHHHHHH
AGVTKHDIIQVAYGYGLFTGGLGLHYGAEKIGASVIPISGGNTKKQLQLLEDFGSTAIAC
HCCCHHHHHHHHHHCHHHCCCCCCCCCHHHHCCEEEEECCCCHHHHHHHHHHCCCCEEEE
TPSYAAYLGEAIMEEKLDRSKIKLKAGIFGAEPWTEEMRSQIQQLLGIKAYDIYGLSEVI
CCHHHHHHHHHHHHHHHCHHHEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEECCHHHHH
GPGVSMECSIQHGMHVFEDHFIPEIINPETGEVLPYGELGELVFTAVTKEALPLLRYRTR
CCCCCEEEEHHHCHHHHHHCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
DLTRLHVERCDCGRTLVRMEKCVGRSDDMLIIRGVNVFPSQVESVLLEMSETKPHYLLVV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEE
DRQNNLDTLEIQVEVEDQFFSDEVKELEGLRKRISGNLTSILGLHANVRLVEPGTIERSQ
ECCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCEEEECCCCCCCCC
GKAQRVVDKRKLNEHKETP
CHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]