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The map label for this gene is lysN [H]

Identifier: 21672951

GI number: 21672951

Start: 105168

End: 106361

Strand: Reverse

Name: lysN [H]

Synonym: CT0110

Alternate gene names: 21672951

Gene position: 106361-105168 (Counterclockwise)

Preceding gene: 21672952

Following gene: 21672948

Centisome position: 4.94

GC content: 60.8

Gene sequence:

>1194_bases
ATGCCACGATTTTCGAAATCCGTTTCTGCATTGCGCTCCTCAGCGATCAGGGAGCTAATGAGCCTCGCTTCTCGCCCTGA
TATTCTCTCGTTTGCGGGAGGAATGCCGGGTAACGAGCTGTTTCCGATCGATGAGGTCGAGGAGCTGTTCCGGAACCTCG
ACACCAAAACCAAACAGGCCGCGTTCCAGTACGGCCCGACACCCGGCCTGCCCTCACTGCTCGAATCGCTTGGCGGTTTT
CTGGAACGCAAAGGCCTGCCAGTCAAGAAGAACCGCCTCATGATCACCACCGGATCACAGCAGGCTCTGAGTATTTTTGC
CCGCGCTTTCGTCGATCCGGGCGACCGGGTGCTGACCGAGTACCCCTGCTTCATCGGAGCCATCGCGGCGTTCCGCGCCT
GCGGAGCCGAGATCGTCTCGCTGCCGGTCGATGAAGCGGGCATCGACATCGCCATGCTCCGTCAGGAGGTGGAGAATCCC
GACCCGGCGAAGTTTCTCTACATCACACCGTACTTCCACAACCCGGCGGGAATGCTCTACAGCACCAACCGCAAGAGGAA
GCTGATCAAAGCGTTACAGGGGCGCGACATTCCGCTGCTCGAAGACGACGCTTACGGCGACCTCTGGTTCAGCGACGAAC
ACCGCGAAGCCCTGCAACCCATCAAGGCGATCGATCCGGAGGACATCGACGTCTGCTACATGGGCTCCTTCTCCAAGATT
CTCGGCCCGGGCCTGCGCCTTGGCTGGATGCTGGCGCCAGAGGCAATCTACGAAAAGTGCGAGCTGATCAAGCAGTCCGC
CGACGCCTGTTCGTCAAGCTTCACCCAGGTCATCGCCGACGCATTCATCCGCTCGGGCAGGATCGATACATACGTCGCTT
CGGTGCGCGAAGAGTACAAGCGCCGCGCCGCCTCCATGGTCAAAGCCCTGCGAAGCAACCTGCCCGCCTACGTCCGCTGG
AACGAACCGAAAGGCGGGTTCTACATCTGGCTGACCCTGCCGGAGGGAGCCGACGCCACTGAAATACTCAAGCGCGCCAT
CGAAGGCGGCGCGGTCTTCGTCACCGGCAGCACCTTCGACCCGCAAGGAACACGCAACAACACCATGCGCCTCTCCTACT
GCAACAACACCCCGGAAGAGATCGAACGCGGCATTCCCATCATCACCCGCGCCATCCGCGAGGTGTGCGGGTAA

Upstream 100 bases:

>100_bases
GCCACAGAAGGCCATCGAGGTGCTGCAACTGCACAAGATGGAGCTGCTCAAGACGGGCGATGTGTACCAGCTCTGAGAAA
AGGCCAATCATTGAAACCCA

Downstream 100 bases:

>100_bases
AAACATCACACCAAAAAGCCTCGGCACACTCGCCAGGATTGCGAACGGCCAAAAAATGCGAAACCCCCGACGTTGCGGGG
GTTTCGTGGCAATTATGTCA

Product: aminotransferase, class I

Products: NA

Alternate protein names: 2-aminoadipate aminotransferase; Alpha-aminoadipate aminotransferase; AAA-AT; AadAT [H]

Number of amino acids: Translated: 397; Mature: 396

Protein sequence:

>397_residues
MPRFSKSVSALRSSAIRELMSLASRPDILSFAGGMPGNELFPIDEVEELFRNLDTKTKQAAFQYGPTPGLPSLLESLGGF
LERKGLPVKKNRLMITTGSQQALSIFARAFVDPGDRVLTEYPCFIGAIAAFRACGAEIVSLPVDEAGIDIAMLRQEVENP
DPAKFLYITPYFHNPAGMLYSTNRKRKLIKALQGRDIPLLEDDAYGDLWFSDEHREALQPIKAIDPEDIDVCYMGSFSKI
LGPGLRLGWMLAPEAIYEKCELIKQSADACSSSFTQVIADAFIRSGRIDTYVASVREEYKRRAASMVKALRSNLPAYVRW
NEPKGGFYIWLTLPEGADATEILKRAIEGGAVFVTGSTFDPQGTRNNTMRLSYCNNTPEEIERGIPIITRAIREVCG

Sequences:

>Translated_397_residues
MPRFSKSVSALRSSAIRELMSLASRPDILSFAGGMPGNELFPIDEVEELFRNLDTKTKQAAFQYGPTPGLPSLLESLGGF
LERKGLPVKKNRLMITTGSQQALSIFARAFVDPGDRVLTEYPCFIGAIAAFRACGAEIVSLPVDEAGIDIAMLRQEVENP
DPAKFLYITPYFHNPAGMLYSTNRKRKLIKALQGRDIPLLEDDAYGDLWFSDEHREALQPIKAIDPEDIDVCYMGSFSKI
LGPGLRLGWMLAPEAIYEKCELIKQSADACSSSFTQVIADAFIRSGRIDTYVASVREEYKRRAASMVKALRSNLPAYVRW
NEPKGGFYIWLTLPEGADATEILKRAIEGGAVFVTGSTFDPQGTRNNTMRLSYCNNTPEEIERGIPIITRAIREVCG
>Mature_396_residues
PRFSKSVSALRSSAIRELMSLASRPDILSFAGGMPGNELFPIDEVEELFRNLDTKTKQAAFQYGPTPGLPSLLESLGGFL
ERKGLPVKKNRLMITTGSQQALSIFARAFVDPGDRVLTEYPCFIGAIAAFRACGAEIVSLPVDEAGIDIAMLRQEVENPD
PAKFLYITPYFHNPAGMLYSTNRKRKLIKALQGRDIPLLEDDAYGDLWFSDEHREALQPIKAIDPEDIDVCYMGSFSKIL
GPGLRLGWMLAPEAIYEKCELIKQSADACSSSFTQVIADAFIRSGRIDTYVASVREEYKRRAASMVKALRSNLPAYVRWN
EPKGGFYIWLTLPEGADATEILKRAIEGGAVFVTGSTFDPQGTRNNTMRLSYCNNTPEEIERGIPIITRAIREVCG

Specific function: Catalyzes the transfer of an amino group between 2- oxoadipate (2-OA) and glutamate (Glu) to yield alpha-aminodipate (AAA). It can also transaminate glutamate, leucine, and aromatic amino acids. It also conbtributes in the biosynthesis of other amino acid

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=431, Percent_Identity=25.9860788863109, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI33469970, Length=431, Percent_Identity=25.9860788863109, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI4507369, Length=368, Percent_Identity=22.8260869565217, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1790797, Length=330, Percent_Identity=29.6969696969697, Blast_Score=151, Evalue=8e-38,
Organism=Escherichia coli, GI1787710, Length=384, Percent_Identity=27.0833333333333, Blast_Score=151, Evalue=9e-38,
Organism=Escherichia coli, GI1788722, Length=372, Percent_Identity=23.1182795698925, Blast_Score=69, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6321236, Length=439, Percent_Identity=25.5125284738041, Blast_Score=106, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6321000, Length=242, Percent_Identity=28.9256198347107, Blast_Score=87, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6321929, Length=356, Percent_Identity=23.314606741573, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21356535, Length=383, Percent_Identity=26.1096605744125, Blast_Score=128, Evalue=7e-30,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.39 [H]

Molecular weight: Translated: 44013; Mature: 43882

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRFSKSVSALRSSAIRELMSLASRPDILSFAGGMPGNELFPIDEVEELFRNLDTKTKQA
CCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCHHHHHHHHHHCCCHHHHH
AFQYGPTPGLPSLLESLGGFLERKGLPVKKNRLMITTGSQQALSIFARAFVDPGDRVLTE
HHHCCCCCCHHHHHHHHHHHHHHCCCCEECCEEEEEECCHHHHHHHHHHHCCCCHHHHHH
YPCFIGAIAAFRACGAEIVSLPVDEAGIDIAMLRQEVENPDPAKFLYITPYFHNPAGMLY
HHHHHHHHHHHHHCCHHHEECCCCCCCCHHHHHHHHHCCCCCCEEEEEECEEECCCCCEE
STNRKRKLIKALQGRDIPLLEDDAYGDLWFSDEHREALQPIKAIDPEDIDVCYMGSFSKI
ECCHHHHHHHHHCCCCCCEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEECCCHHHH
LGPGLRLGWMLAPEAIYEKCELIKQSADACSSSFTQVIADAFIRSGRIDTYVASVREEYK
HCCCCCCHHEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
RRAASMVKALRSNLPAYVRWNEPKGGFYIWLTLPEGADATEILKRAIEGGAVFVTGSTFD
HHHHHHHHHHHHCCCEEEEECCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCC
PQGTRNNTMRLSYCNNTPEEIERGIPIITRAIREVCG
CCCCCCCCEEEEECCCCHHHHHCCCHHHHHHHHHHCC
>Mature Secondary Structure 
PRFSKSVSALRSSAIRELMSLASRPDILSFAGGMPGNELFPIDEVEELFRNLDTKTKQA
CCHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCHHHHHHHHHHCCCHHHHH
AFQYGPTPGLPSLLESLGGFLERKGLPVKKNRLMITTGSQQALSIFARAFVDPGDRVLTE
HHHCCCCCCHHHHHHHHHHHHHHCCCCEECCEEEEEECCHHHHHHHHHHHCCCCHHHHHH
YPCFIGAIAAFRACGAEIVSLPVDEAGIDIAMLRQEVENPDPAKFLYITPYFHNPAGMLY
HHHHHHHHHHHHHCCHHHEECCCCCCCCHHHHHHHHHCCCCCCEEEEEECEEECCCCCEE
STNRKRKLIKALQGRDIPLLEDDAYGDLWFSDEHREALQPIKAIDPEDIDVCYMGSFSKI
ECCHHHHHHHHHCCCCCCEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEECCCHHHH
LGPGLRLGWMLAPEAIYEKCELIKQSADACSSSFTQVIADAFIRSGRIDTYVASVREEYK
HCCCCCCHHEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
RRAASMVKALRSNLPAYVRWNEPKGGFYIWLTLPEGADATEILKRAIEGGAVFVTGSTFD
HHHHHHHHHHHHCCCEEEEECCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCC
PQGTRNNTMRLSYCNNTPEEIERGIPIITRAIREVCG
CCCCCCCCEEEEECCCCHHHHHCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA