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The map label for this gene is arcR

Identifier: 15925621

GI number: 15925621

Start: 2784992

End: 2785696

Strand: Reverse

Name: arcR

Synonym: SAV2631

Alternate gene names: 15925621

Gene position: 2785696-2784992 (Counterclockwise)

Preceding gene: 161375860

Following gene: 15925620

Centisome position: 96.77

GC content: 29.22

Gene sequence:

>705_bases
ATGACAGAAAACTTTATTTTGGGTAGAAATAATAAATTAGAACATGAACTAAAGGCATTAGCAGATTACATTAATATCCC
ATATAGTATATTACAACCATATCAAAGTGAATGTTTTGTCAGACATTATACGAAAGGCCAAGTTATTTATTTTTCGCCAC
AAGAAAGTAGCAATATTTACTTTTTAATTGAAGGTAATATTATTAGAGAACATTACAATCAAAATGGAGATGTATATCGT
TATTTTAATAAAGAGCAAGTATTATTTCCAATCAGTAACTTATTTCATCCGAAAGAGGTTAACGAATTGTGTACAGCATT
AACCGATTGTACAGTTCTTGGATTGCCTAGAGAATTGATGGCTTTTTTGTGCAAAGCTAATGATGATATATTTTTGACAC
TTTTTGCATTAATAAATGATAATGAGCAGCAACACATGAACTATAACATGGCATTAACAAGTAAATTTGCTAAAGATCGA
ATTATTAAATTGTTATGTCATCTATGTCAGACAGTAGGGTACGATCAAGATGAATTTTATGAAATCAAACAGTTTTTAAC
TATTCAACTCATGAGTGATATGGCTGGGATTTCCCGGGAAACAGCTGGTCATATTATTCATGAACTTAAAGATGAAAAAC
TTGTTGTTAAAGATCATAAAAATTGGTTAGTAAGCAAACATTTATTCAATGATGTATGTGTTTAA

Upstream 100 bases:

>100_bases
AGCACTTTATCACGCGACAAAACATTAAATATGTTTCTCCGTTGATTCAAATGAAAAAGTTGTCTGCTGACACTTTGCAA
GGTTTGAAGGAGTTTAACTT

Downstream 100 bases:

>100_bases
TATACAATGTAAAATGAATAAGTTGAACATGAGGTCTAACGTACATTTATACGTTAGGCCTTTTTTGCTAGCATGATGAA
TAATTTAAAATGTTAGTTAA

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MTENFILGRNNKLEHELKALADYINIPYSILQPYQSECFVRHYTKGQVIYFSPQESSNIYFLIEGNIIREHYNQNGDVYR
YFNKEQVLFPISNLFHPKEVNELCTALTDCTVLGLPRELMAFLCKANDDIFLTLFALINDNEQQHMNYNMALTSKFAKDR
IIKLLCHLCQTVGYDQDEFYEIKQFLTIQLMSDMAGISRETAGHIIHELKDEKLVVKDHKNWLVSKHLFNDVCV

Sequences:

>Translated_234_residues
MTENFILGRNNKLEHELKALADYINIPYSILQPYQSECFVRHYTKGQVIYFSPQESSNIYFLIEGNIIREHYNQNGDVYR
YFNKEQVLFPISNLFHPKEVNELCTALTDCTVLGLPRELMAFLCKANDDIFLTLFALINDNEQQHMNYNMALTSKFAKDR
IIKLLCHLCQTVGYDQDEFYEIKQFLTIQLMSDMAGISRETAGHIIHELKDEKLVVKDHKNWLVSKHLFNDVCV
>Mature_233_residues
TENFILGRNNKLEHELKALADYINIPYSILQPYQSECFVRHYTKGQVIYFSPQESSNIYFLIEGNIIREHYNQNGDVYRY
FNKEQVLFPISNLFHPKEVNELCTALTDCTVLGLPRELMAFLCKANDDIFLTLFALINDNEQQHMNYNMALTSKFAKDRI
IKLLCHLCQTVGYDQDEFYEIKQFLTIQLMSDMAGISRETAGHIIHELKDEKLVVKDHKNWLVSKHLFNDVCV

Specific function: Positively regulates the expression of the arcABDCR operon under anaerobic conditions, thus playing an essential role in arginine catabolism. May also control the expression of genes encoding proteins which are involved in anaerobic metabolism. Can bind c

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARCR_STAA1 (A7X715)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001443205.1
- ProteinModelPortal:   A7X715
- SMR:   A7X715
- STRING:   A7X715
- EnsemblBacteria:   EBSTAT00000003697
- GeneID:   5560087
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_2615
- eggNOG:   COG0664
- GeneTree:   EBGT00050000024252
- HOGENOM:   HBG694023
- OMA:   GISRETT
- ProtClustDB:   CLSK886120
- BioCyc:   SAUR418127:SAHV_2615-MONOMER
- GO:   GO:0005737
- GO:   GO:0006350
- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR011991
- Gene3D:   G3DSA:2.60.120.10
- Gene3D:   G3DSA:1.10.10.10

Pfam domain/function: PF00027 cNMP_binding; SSF51206 cNMP_binding

EC number: NA

Molecular weight: Translated: 27429; Mature: 27298

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS00888 CNMP_BINDING_1; PS00889 CNMP_BINDING_2; PS50042 CNMP_BINDING_3; PS00042 HTH_CRP_1; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTENFILGRNNKLEHELKALADYINIPYSILQPYQSECFVRHYTKGQVIYFSPQESSNIY
CCCCEEECCCCCHHHHHHHHHHHHCCCHHHHCCHHHHHHHEECCCCEEEEECCCCCCCEE
FLIEGNIIREHYNQNGDVYRYFNKEQVLFPISNLFHPKEVNELCTALTDCTVLGLPRELM
EEEECCEEEHHHCCCCCEEEEECCCEEEEEHHHCCCHHHHHHHHHHHHHHHHCCCCHHHH
AFLCKANDDIFLTLFALINDNEQQHMNYNMALTSKFAKDRIIKLLCHLCQTVGYDQDEFY
HHHHCCCCCCEEEEEEHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
EIKQFLTIQLMSDMAGISRETAGHIIHELKDEKLVVKDHKNWLVSKHLFNDVCV
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
TENFILGRNNKLEHELKALADYINIPYSILQPYQSECFVRHYTKGQVIYFSPQESSNIY
CCCEEECCCCCHHHHHHHHHHHHCCCHHHHCCHHHHHHHEECCCCEEEEECCCCCCCEE
FLIEGNIIREHYNQNGDVYRYFNKEQVLFPISNLFHPKEVNELCTALTDCTVLGLPRELM
EEEECCEEEHHHCCCCCEEEEECCCEEEEEHHHCCCHHHHHHHHHHHHHHHHCCCCHHHH
AFLCKANDDIFLTLFALINDNEQQHMNYNMALTSKFAKDRIIKLLCHLCQTVGYDQDEFY
HHHHCCCCCCEEEEEEHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
EIKQFLTIQLMSDMAGISRETAGHIIHELKDEKLVVKDHKNWLVSKHLFNDVCV
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA