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The map label for this gene is agrB

Identifier: 15925026

GI number: 15925026

Start: 2155876

End: 2156439

Strand: Direct

Name: agrB

Synonym: SAV2036

Alternate gene names: 15925026

Gene position: 2155876-2156439 (Clockwise)

Preceding gene: 15925024

Following gene: 15925027

Centisome position: 74.9

GC content: 25.71

Gene sequence:

>564_bases
TTGAATTATTTTGATAACAAAATTGACCAGTTTGCCACGTATCTTCAAAAGAGAAATAACTTAGATCATATTCAATTTTT
GCAAGTACGTTTAGGGATGCAAATTATAGTTGGTAATTTTTTTAAAATACTTGTAACATATAGTATTTCTATATTCTTAA
GTGTATTTTTGTTTACCTTAGTTACACACTTATCCTATATGTTAATACGCTATAATGCACATGGTGCTCATGCAAAGTCT
TCGATACTTTGTTACATACAAAGTATTTTAACATTTGTATTTGTACCTTATTTTCTAATTAATATAGACATTAATTTTAC
TTATTTACTGGCCTTATCTATTATAGGATTGATTTCCGTTGTTATTTATGCACCTGCAGCAACGAAAAAGCAACCTATAC
CAATAAAATTAGTAAAACGTAAAAAGTATTTATCTATAATTATGTATTTATTAGTTTTGATTCTATCCTTAATAATACAT
CCATTTTATGCTCAATTTATGTTATTAGGAATTTTAGTGGAATCTATTACATTATTACCTATTTTTTTCCCTAAGGAGGA
TTAA

Upstream 100 bases:

>100_bases
TTACATTTAACAGTTAAGTATTTATTTCCTACAGTTAGGCAATATAATGATAAAAGATTGTACTAAATCGTATAATAACA
GTGAGGAGAGTGGTGTAAAA

Downstream 100 bases:

>100_bases
TCATGAATACACTTGTTAATATGTTTTTTGATTTTATAATTAAATTAGCTAAAGCAATCGGAATTGTCGGTGGCGTAAAC
GCTTGCAGCAGTTTATTTGA

Product: accessory gene regulator B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MNYFDNKIDQFATYLQKRNNLDHIQFLQVRLGMQIIVGNFFKILVTYSISIFLSVFLFTLVTHLSYMLIRYNAHGAHAKS
SILCYIQSILTFVFVPYFLINIDINFTYLLALSIIGLISVVIYAPAATKKQPIPIKLVKRKKYLSIIMYLLVLILSLIIH
PFYAQFMLLGILVESITLLPIFFPKED

Sequences:

>Translated_187_residues
MNYFDNKIDQFATYLQKRNNLDHIQFLQVRLGMQIIVGNFFKILVTYSISIFLSVFLFTLVTHLSYMLIRYNAHGAHAKS
SILCYIQSILTFVFVPYFLINIDINFTYLLALSIIGLISVVIYAPAATKKQPIPIKLVKRKKYLSIIMYLLVLILSLIIH
PFYAQFMLLGILVESITLLPIFFPKED
>Mature_187_residues
MNYFDNKIDQFATYLQKRNNLDHIQFLQVRLGMQIIVGNFFKILVTYSISIFLSVFLFTLVTHLSYMLIRYNAHGAHAKS
SILCYIQSILTFVFVPYFLINIDINFTYLLALSIIGLISVVIYAPAATKKQPIPIKLVKRKKYLSIIMYLLVLILSLIIH
PFYAQFMLLGILVESITLLPIFFPKED

Specific function: Essential for the production of a quorum sensing system signal molecule, the autoinducing peptide (AIP). This quorum sensing system is responsible for the regulation of the expression of virulence factor genes. Involved in the proteolytic processing of Ag

COG id: COG4512

COG function: function code OTK; Membrane protein putatively involved in post-translational modification of the autoinducing quorum-sensing peptide

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AgrB family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AGRB_STAA1 (A7X4K2)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001442611.1
- STRING:   A7X4K2
- MEROPS:   C75.001
- EnsemblBacteria:   EBSTAT00000005080
- GeneID:   5559015
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_2021
- eggNOG:   COG4512
- GeneTree:   EBGT00050000024407
- HOGENOM:   HBG692974
- OMA:   KSDEAEN
- ProtClustDB:   CLSK885730
- BioCyc:   SAUR418127:SAHV_2021-MONOMER
- GO:   GO:0009405
- HAMAP:   MF_00784
- InterPro:   IPR006741
- SMART:   SM00793

Pfam domain/function: PF04647 AgrB

EC number: NA

Molecular weight: Translated: 21681; Mature: 21681

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xfa914ec)-; HASH(0xfe5ede8)-; HASH(0xc7a459c)-; HASH(0xfa8ed84)-; HASH(0xfe8b020)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYFDNKIDQFATYLQKRNNLDHIQFLQVRLGMQIIVGNFFKILVTYSISIFLSVFLFTL
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTHLSYMLIRYNAHGAHAKSSILCYIQSILTFVFVPYFLINIDINFTYLLALSIIGLISV
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
VIYAPAATKKQPIPIKLVKRKKYLSIIMYLLVLILSLIIHPFYAQFMLLGILVESITLLP
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFFPKED
EECCCCH
>Mature Secondary Structure
MNYFDNKIDQFATYLQKRNNLDHIQFLQVRLGMQIIVGNFFKILVTYSISIFLSVFLFTL
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTHLSYMLIRYNAHGAHAKSSILCYIQSILTFVFVPYFLINIDINFTYLLALSIIGLISV
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
VIYAPAATKKQPIPIKLVKRKKYLSIIMYLLVLILSLIIHPFYAQFMLLGILVESITLLP
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFFPKED
EECCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA