BacMap

Definition	Staphylococcus aureus subsp. aureus Mu50, complete genome.
Accession	NC_002758
Length	2,878,529

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The map label for this gene is yvfR [H]

Identifier: 15924308

GI number: 15924308

Start: 1394023

End: 1394520

Strand: Direct

Name: yvfR [H]

Synonym: SAV1318

Alternate gene names: 15924308

Gene position: 1394023-1394520 (Clockwise)

Preceding gene: 15924307

Following gene: 57634629

Centisome position: 48.43

GC content: 27.51

Gene sequence:

>498_bases
TTGATTCAAATATCTAATATCAACAAGTCATTTAATAAAAGATGTGTTCTAAAAAATATTTCGTTCGATATTGAACAAGG
TAAATGTATCGCTTTAATTGGAAAAAATGGTGCTGGAAAGTCAACGTTAATTGATATATTAATTGGTAATGTTAATGCTA
ATTCTGGTGAGATATTTGATAAAGACAAGTTATTACAAAGTGAAAATCGCAGTATAATGTTCCAAAAAACGATGTTTCCA
GATCAATTAAAAGTTATTGAGATTATCAACTTATATCAATCATTTTACGAAAATCCATTACCATTGGAAGAAATAATAGA
ACTGACGAAATTTGATTCTAGTCAACTGAACCAATTTGTAAATAAACTTTCTGGTGGTCAACAACGATTACTCGATTTTG
TATTATCTTTAATCGGACAACCACAATTGATCTTATTAGATGAACCAACATCGACTATGGATATAGAAATTAGAGAATAT
TTTTGGTCAATTATTTAA

Upstream 100 bases:

>100_bases
AATAATGACATTTGTCATTTCAAATCTATGACAAAGTGTTCTATTTTAAATCTAATAAATTTACTAATATTAAATTAAGA
AAAAAATAGAGGTGATTAAA

Downstream 100 bases:

>100_bases
AATTTAAAAGAAGATAATCGAACGATACTCTATACATCGCACTATATTGAAGAAGTCGAACGTATGTCAGACAAAATTAT
TCTCATTGAAAATGGAGAAA

Product: ABC transporter

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MIQISNINKSFNKRCVLKNISFDIEQGKCIALIGKNGAGKSTLIDILIGNVNANSGEIFDKDKLLQSENRSIMFQKTMFP
DQLKVIEIINLYQSFYENPLPLEEIIELTKFDSSQLNQFVNKLSGGQQRLLDFVLSLIGQPQLILLDEPTSTMDIEIREY
FWSII

Sequences:

>Translated_165_residues
MIQISNINKSFNKRCVLKNISFDIEQGKCIALIGKNGAGKSTLIDILIGNVNANSGEIFDKDKLLQSENRSIMFQKTMFP
DQLKVIEIINLYQSFYENPLPLEEIIELTKFDSSQLNQFVNKLSGGQQRLLDFVLSLIGQPQLILLDEPTSTMDIEIREY
FWSII
>Mature_165_residues
MIQISNINKSFNKRCVLKNISFDIEQGKCIALIGKNGAGKSTLIDILIGNVNANSGEIFDKDKLLQSENRSIMFQKTMFP
DQLKVIEIINLYQSFYENPLPLEEIIELTKFDSSQLNQFVNKLSGGQQRLLDFVLSLIGQPQLILLDEPTSTMDIEIREY
FWSII

Specific function: Involved In The High-Affinity Zinc Uptake Transport System. [C]

COG id: COG1131

COG function: function code V; ABC-type multidrug transport system, ATPase component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI27262624, Length=186, Percent_Identity=29.0322580645161, Blast_Score=87, Evalue=7e-18,
Organism=Homo sapiens, GI27262626, Length=186, Percent_Identity=29.0322580645161, Blast_Score=87, Evalue=7e-18,
Organism=Homo sapiens, GI153792144, Length=167, Percent_Identity=31.1377245508982, Blast_Score=82, Evalue=2e-16,
Organism=Homo sapiens, GI45446740, Length=181, Percent_Identity=29.2817679558011, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI47078218, Length=181, Percent_Identity=29.2817679558011, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI27477115, Length=184, Percent_Identity=31.5217391304348, Blast_Score=78, Evalue=4e-15,
Organism=Homo sapiens, GI27881501, Length=180, Percent_Identity=29.4444444444444, Blast_Score=77, Evalue=5e-15,
Organism=Homo sapiens, GI30795238, Length=180, Percent_Identity=29.4444444444444, Blast_Score=77, Evalue=6e-15,
Organism=Homo sapiens, GI6005701, Length=168, Percent_Identity=30.952380952381, Blast_Score=75, Evalue=2e-14,
Organism=Homo sapiens, GI105990541, Length=153, Percent_Identity=32.0261437908497, Blast_Score=72, Evalue=2e-13,
Organism=Homo sapiens, GI21536376, Length=176, Percent_Identity=26.1363636363636, Blast_Score=71, Evalue=5e-13,
Organism=Homo sapiens, GI27436953, Length=158, Percent_Identity=30.379746835443, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI31657092, Length=181, Percent_Identity=27.0718232044199, Blast_Score=66, Evalue=1e-11,
Organism=Escherichia coli, GI1788165, Length=167, Percent_Identity=31.1377245508982, Blast_Score=82, Evalue=1e-17,
Organism=Escherichia coli, GI1786319, Length=160, Percent_Identity=31.25, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1787029, Length=183, Percent_Identity=26.775956284153, Blast_Score=74, Evalue=4e-15,
Organism=Escherichia coli, GI87082268, Length=161, Percent_Identity=29.1925465838509, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI87081709, Length=169, Percent_Identity=26.0355029585799, Blast_Score=71, Evalue=3e-14,
Organism=Escherichia coli, GI1788897, Length=165, Percent_Identity=28.4848484848485, Blast_Score=71, Evalue=3e-14,
Organism=Escherichia coli, GI87081791, Length=175, Percent_Identity=29.7142857142857, Blast_Score=70, Evalue=5e-14,
Organism=Escherichia coli, GI1787041, Length=159, Percent_Identity=25.7861635220126, Blast_Score=70, Evalue=9e-14,
Organism=Escherichia coli, GI1790467, Length=170, Percent_Identity=25.8823529411765, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1788225, Length=183, Percent_Identity=26.775956284153, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1787547, Length=182, Percent_Identity=25.8241758241758, Blast_Score=68, Evalue=3e-13,
Organism=Escherichia coli, GI2367384, Length=160, Percent_Identity=29.375, Blast_Score=67, Evalue=5e-13,
Organism=Escherichia coli, GI1789751, Length=171, Percent_Identity=26.3157894736842, Blast_Score=67, Evalue=5e-13,
Organism=Escherichia coli, GI1787370, Length=171, Percent_Identity=28.6549707602339, Blast_Score=67, Evalue=6e-13,
Organism=Escherichia coli, GI1789672, Length=173, Percent_Identity=30.0578034682081, Blast_Score=67, Evalue=6e-13,
Organism=Escherichia coli, GI1786563, Length=179, Percent_Identity=24.0223463687151, Blast_Score=65, Evalue=2e-12,
Organism=Escherichia coli, GI48994943, Length=181, Percent_Identity=25.9668508287293, Blast_Score=65, Evalue=2e-12,
Organism=Escherichia coli, GI1790739, Length=174, Percent_Identity=28.1609195402299, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1788506, Length=169, Percent_Identity=28.4023668639053, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1789891, Length=166, Percent_Identity=25.9036144578313, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1786703, Length=174, Percent_Identity=25.2873563218391, Blast_Score=63, Evalue=7e-12,
Organism=Escherichia coli, GI1786975, Length=165, Percent_Identity=28.4848484848485, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1786654, Length=172, Percent_Identity=29.0697674418605, Blast_Score=62, Evalue=1e-11,
Organism=Escherichia coli, GI87081834, Length=190, Percent_Identity=27.3684210526316, Blast_Score=62, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115533608, Length=183, Percent_Identity=28.9617486338798, Blast_Score=77, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17565586, Length=166, Percent_Identity=31.3253012048193, Blast_Score=77, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71983510, Length=166, Percent_Identity=29.5180722891566, Blast_Score=70, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71983516, Length=166, Percent_Identity=29.5180722891566, Blast_Score=70, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71983523, Length=166, Percent_Identity=29.5180722891566, Blast_Score=70, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17510237, Length=167, Percent_Identity=26.9461077844311, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71992285, Length=169, Percent_Identity=29.585798816568, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI116007184, Length=171, Percent_Identity=29.2397660818713, Blast_Score=80, Evalue=9e-16,
Organism=Drosophila melanogaster, GI221500365, Length=171, Percent_Identity=29.2397660818713, Blast_Score=79, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24666092, Length=174, Percent_Identity=31.0344827586207, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24582014, Length=166, Percent_Identity=28.9156626506024, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24582012, Length=166, Percent_Identity=28.9156626506024, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI281362751, Length=177, Percent_Identity=25.9887005649718, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24650853, Length=167, Percent_Identity=27.5449101796407, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI221512771, Length=175, Percent_Identity=26.8571428571429, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24650855, Length=167, Percent_Identity=27.5449101796407, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28571209, Length=169, Percent_Identity=27.2189349112426, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI85725262, Length=163, Percent_Identity=27.6073619631902, Blast_Score=66, Evalue=8e-12,
Organism=Drosophila melanogaster, GI28573571, Length=176, Percent_Identity=25, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 18835; Mature: 18835

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQISNINKSFNKRCVLKNISFDIEQGKCIALIGKNGAGKSTLIDILIGNVNANSGEIFD
CEEECCCCCCCCCEEEEECCCEEECCCCEEEEEECCCCCHHEEEEEEEECCCCCCCCCCC
KDKLLQSENRSIMFQKTMFPDQLKVIEIINLYQSFYENPLPLEEIIELTKFDSSQLNQFV
HHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHH
NKLSGGQQRLLDFVLSLIGQPQLILLDEPTSTMDIEIREYFWSII
HHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEHHHHHHHHCC
>Mature Secondary Structure
MIQISNINKSFNKRCVLKNISFDIEQGKCIALIGKNGAGKSTLIDILIGNVNANSGEIFD
CEEECCCCCCCCCEEEEECCCEEECCCCEEEEEECCCCCHHEEEEEEEECCCCCCCCCCC
KDKLLQSENRSIMFQKTMFPDQLKVIEIINLYQSFYENPLPLEEIIELTKFDSSQLNQFV
HHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHH
NKLSGGQQRLLDFVLSLIGQPQLILLDEPTSTMDIEIREYFWSII
HHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]