Click here to switch to the map view.

The map label for this gene is glpT [H]

Identifier: 15923327

GI number: 15923327

Start: 382733

End: 383797

Strand: Reverse

Name: glpT [H]

Synonym: SAV0337

Alternate gene names: 15923327

Gene position: 383797-382733 (Counterclockwise)

Preceding gene: 15923331

Following gene: 15923326

Centisome position: 13.33

GC content: 37.28

Gene sequence:

>1065_bases
ATGAATTTTCTTAAACCTGCAAAGCATATTAAGCCTTTGCCAGAAAATCAGATAGATGATACCTATAAACGATTACGTCT
CCAAGTATTTCTTGGTATTTTCATCGGTTACGCTGGGTACTATTTATTACGTAAAAACTTTTCATTAGCGATGCCAGCAT
TGCAAGAGCAAGGTTTTACAAAAGCGGAACTAGGTTTTGCACTTTCTGCTGTTTCCATCGCATATGGATTTAGTAAGTTC
TTTATGGGTACTGTAAGTGATCGGAGCAATGCTCGGATATTCTTAGTTCTTGGATTAGCACTCACTGCTATCGTCAATTT
GTTAATGGGATTTGTACCGTTCTTTACATCAGGTATCGGTATTATGTTTGTCCTATTATTCTTAAATGGATGGTTTCAAG
GTATGGGCTGGCCACCTTCAGGCCGTGTTCTCGTTCACTGGTTTAGTGTAAGTGAACGCGGAAGTAAGACTGCCCTTTGG
AACGTTGCGCATAATGTTGGTGGAGGTATTATGGCACCTATTGCTGCTTGGGGTATTACAACAACAGCATTTATCAACTT
TGGTTATTTAAAAGGTTTCGAAGGTGTATTCATTTACCCTGCACTCTTAGCACTTATCATTGCCGCAATTTCATACGTAT
TGATTAGAGACACACCTCAATCTCAAGGTTTACCTCCAATCGAAATTTATAAAAACGACTTTGCTACAAGCGATAAGAAA
ACATTAGAAACAGAATTAACTACAAAAGAAATTTTATTTAAATATGTACTGAACAATAAATGGGTATGGGCAATTGCCTT
TGCAAATATATTTGTTTATTTCGTGCGTTATGGTGTACTTGATTGGGCGCCAGTCTACTTAAGTGAAGAAAAACATTTCG
ACTTAAAAGCATCAGGTTGGGCATACTTCTTATACGAATGGGCTGGAATTCCTGGTACATTATTATGTGGTTACATTTCT
GATAAATTATTCAAAGGTCGTCGTGGACCTGCAGGTTTCTTCTTTATGTTAGGTGTCACAGTATTTGTATTAATTTATTG
GTTAAATCCTCCAGGCAATGCTTAG

Upstream 100 bases:

>100_bases
TATGCAAGATTTCACAAAAGTATATTGACAACGCTTTCATACATGTCTAATATAAGTTTATCGCACAAAATGCATATAAA
TACATATTAAGGAGGATTTT

Downstream 100 bases:

>100_bases
TTAGACAATGTCTCATTAATTGCCATTGGTTTCTTAATATATGGACCAGTTATGTTAATTGGTTTACAAGCATTAGATTA
TGTACCTAAAAAAGCAGCTG

Product: glycerol-3-phosphate transporter

Products: Proton [Cytoplasm]; glycerol-3-phosphate [Cytoplasm] [C]

Alternate protein names: G-3-P transporter; G-3-P permease [H]

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MNFLKPAKHIKPLPENQIDDTYKRLRLQVFLGIFIGYAGYYLLRKNFSLAMPALQEQGFTKAELGFALSAVSIAYGFSKF
FMGTVSDRSNARIFLVLGLALTAIVNLLMGFVPFFTSGIGIMFVLLFLNGWFQGMGWPPSGRVLVHWFSVSERGSKTALW
NVAHNVGGGIMAPIAAWGITTTAFINFGYLKGFEGVFIYPALLALIIAAISYVLIRDTPQSQGLPPIEIYKNDFATSDKK
TLETELTTKEILFKYVLNNKWVWAIAFANIFVYFVRYGVLDWAPVYLSEEKHFDLKASGWAYFLYEWAGIPGTLLCGYIS
DKLFKGRRGPAGFFFMLGVTVFVLIYWLNPPGNA

Sequences:

>Translated_354_residues
MNFLKPAKHIKPLPENQIDDTYKRLRLQVFLGIFIGYAGYYLLRKNFSLAMPALQEQGFTKAELGFALSAVSIAYGFSKF
FMGTVSDRSNARIFLVLGLALTAIVNLLMGFVPFFTSGIGIMFVLLFLNGWFQGMGWPPSGRVLVHWFSVSERGSKTALW
NVAHNVGGGIMAPIAAWGITTTAFINFGYLKGFEGVFIYPALLALIIAAISYVLIRDTPQSQGLPPIEIYKNDFATSDKK
TLETELTTKEILFKYVLNNKWVWAIAFANIFVYFVRYGVLDWAPVYLSEEKHFDLKASGWAYFLYEWAGIPGTLLCGYIS
DKLFKGRRGPAGFFFMLGVTVFVLIYWLNPPGNA
>Mature_354_residues
MNFLKPAKHIKPLPENQIDDTYKRLRLQVFLGIFIGYAGYYLLRKNFSLAMPALQEQGFTKAELGFALSAVSIAYGFSKF
FMGTVSDRSNARIFLVLGLALTAIVNLLMGFVPFFTSGIGIMFVLLFLNGWFQGMGWPPSGRVLVHWFSVSERGSKTALW
NVAHNVGGGIMAPIAAWGITTTAFINFGYLKGFEGVFIYPALLALIIAAISYVLIRDTPQSQGLPPIEIYKNDFATSDKK
TLETELTTKEILFKYVLNNKWVWAIAFANIFVYFVRYGVLDWAPVYLSEEKHFDLKASGWAYFLYEWAGIPGTLLCGYIS
DKLFKGRRGPAGFFFMLGVTVFVLIYWLNPPGNA

Specific function: Responsible for glycerol-3-phosphate uptake [H]

COG id: COG2271

COG function: function code G; Sugar phosphate permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family [H]

Homologues:

Organism=Homo sapiens, GI256219543, Length=303, Percent_Identity=30.6930693069307, Blast_Score=128, Evalue=7e-30,
Organism=Homo sapiens, GI256219598, Length=303, Percent_Identity=30.6930693069307, Blast_Score=128, Evalue=8e-30,
Organism=Homo sapiens, GI4503847, Length=303, Percent_Identity=30.6930693069307, Blast_Score=128, Evalue=8e-30,
Organism=Homo sapiens, GI256219483, Length=303, Percent_Identity=30.6930693069307, Blast_Score=128, Evalue=8e-30,
Organism=Homo sapiens, GI256219564, Length=234, Percent_Identity=27.3504273504274, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI49619231, Length=297, Percent_Identity=23.5690235690236, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI38093649, Length=384, Percent_Identity=22.3958333333333, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI223717983, Length=384, Percent_Identity=22.1354166666667, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1788573, Length=353, Percent_Identity=58.0736543909348, Blast_Score=426, Evalue=1e-121,
Organism=Escherichia coli, GI87082310, Length=350, Percent_Identity=37.4285714285714, Blast_Score=218, Evalue=5e-58,
Organism=Escherichia coli, GI2367259, Length=308, Percent_Identity=33.1168831168831, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI2367379, Length=324, Percent_Identity=25.9259259259259, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1789515, Length=350, Percent_Identity=24.2857142857143, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI87082320, Length=312, Percent_Identity=25.3205128205128, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1789152, Length=310, Percent_Identity=24.1935483870968, Blast_Score=72, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17564202, Length=330, Percent_Identity=24.5454545454545, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17564204, Length=262, Percent_Identity=25.5725190839695, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17542316, Length=353, Percent_Identity=24.929178470255, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI133930953, Length=370, Percent_Identity=22.972972972973, Blast_Score=68, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI133901856, Length=362, Percent_Identity=23.4806629834254, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI133901854, Length=362, Percent_Identity=23.4806629834254, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24656866, Length=355, Percent_Identity=23.0985915492958, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI45550478, Length=355, Percent_Identity=23.0985915492958, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24656861, Length=355, Percent_Identity=23.0985915492958, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005267
- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR021159 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 39714; Mature: 39714

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: PS50850 MFS ; PS00942 GLPT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFLKPAKHIKPLPENQIDDTYKRLRLQVFLGIFIGYAGYYLLRKNFSLAMPALQEQGFT
CCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCHHHHCCCC
KAELGFALSAVSIAYGFSKFFMGTVSDRSNARIFLVLGLALTAIVNLLMGFVPFFTSGIG
HHHHHHHHHHHHHHHHHHHHHHEECCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
IMFVLLFLNGWFQGMGWPPSGRVLVHWFSVSERGSKTALWNVAHNVGGGIMAPIAAWGIT
HHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHCCH
TTAFINFGYLKGFEGVFIYPALLALIIAAISYVLIRDTPQSQGLPPIEIYKNDFATSDKK
HHHHEEHHHHCCCCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCEEECCCCCCCCHH
TLETELTTKEILFKYVLNNKWVWAIAFANIFVYFVRYGVLDWAPVYLSEEKHFDLKASGW
HHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHCCCCEEECCCCCCCEECCCE
AYFLYEWAGIPGTLLCGYISDKLFKGRRGPAGFFFMLGVTVFVLIYWLNPPGNA
EEEEEEECCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHEECCCCCC
>Mature Secondary Structure
MNFLKPAKHIKPLPENQIDDTYKRLRLQVFLGIFIGYAGYYLLRKNFSLAMPALQEQGFT
CCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCHHHHCCCC
KAELGFALSAVSIAYGFSKFFMGTVSDRSNARIFLVLGLALTAIVNLLMGFVPFFTSGIG
HHHHHHHHHHHHHHHHHHHHHHEECCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
IMFVLLFLNGWFQGMGWPPSGRVLVHWFSVSERGSKTALWNVAHNVGGGIMAPIAAWGIT
HHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHCCH
TTAFINFGYLKGFEGVFIYPALLALIIAAISYVLIRDTPQSQGLPPIEIYKNDFATSDKK
HHHHEEHHHHCCCCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCEEECCCCCCCCHH
TLETELTTKEILFKYVLNNKWVWAIAFANIFVYFVRYGVLDWAPVYLSEEKHFDLKASGW
HHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHCCCCEEECCCCCCCEECCCE
AYFLYEWAGIPGTLLCGYISDKLFKGRRGPAGFFFMLGVTVFVLIYWLNPPGNA
EEEEEEECCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; glycerol-3-phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + glycerol-3-phosphate [Periplasm] = Proton [Cytoplasm] + glycerol-3-phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8012593; 9384377 [H]