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The map label for this gene is serA-2 [H]

Identifier: 15899892

GI number: 15899892

Start: 2933794

End: 2934696

Strand: Reverse

Name: serA-2 [H]

Synonym: SSO3187

Alternate gene names: 15899892

Gene position: 2934696-2933794 (Counterclockwise)

Preceding gene: 15899893

Following gene: 15899891

Centisome position: 98.08

GC content: 36.77

Gene sequence:

>903_bases
ATGAAGATAATATCTACAGAAAAAGTTCCGGATGAGTGTAAAAATATAATCAGTGTTAAAGATGAGAATATAACGGAAGA
GGATTATAAAAATGCAGAGATCTTGCTAACGTGGCCTGGTAGAGTAAATAACGATCTGATAGGTAAGATGCCTAATCTTA
AGGTAATACAAACGTTTTCGGCGGGAGTTGATGATTTAGACTTCTCTATAATTCCTTCTCATGTTAAAGTATTCTCAAAT
GCGGGTGCTTACTCTTTGTCTGTAGCTGAACACGCTTGGGCTCTAATTTTAGCATCAGCCAAAGGTGTAGGAACAAAAAA
GAGGACTATAGTTTATGATGTTTCTGAAAAAACGTTGTTGATTTTAGGTGGTGGGGGGATAGGATCTGAAGTAGCAAGGA
TAGGTAAAACAGCATTTAGGAATTACGTAATAGGTATTTCCAGATCTTTCAAGAAACCTGAATGGTTTGACGAAAGGCAT
GGAATGACTATGCTAAGGGAGAAAATTGGAGAGGCTGATATAATTGTAGATACGCTACCTCTAAACAAACAAACTAGGGG
TCTTTTAAGTTATGATCTACTTAAAGATATAAGGCGTAATGCCATAATTGTTAATGTTGGGAGAGGTGAGACTGTGGATG
AAGAAGGTATTTATAAGTTACTTAAGGAGAGGCAAGACGTAAGGTTTGGGACTGATGTGTTTTGGAGAAAAAACGGTAAG
GAGGATTTCTATAATACGAAGCTTTGGGAATTAGATAACTTTACTGGAACTCTACACACCGCTGGGGCTTATGGCAATGA
GAGTATAATGAAGAGGGCAATGCTCATAGCTTGTTTAAATGTGAAAAAATATATAGATAGGGGAATTGCAGATAATGAAG
TAAGAAGGGAAGATTATGTTTGA

Upstream 100 bases:

>100_bases
GAAGAGGGAAGAAAACTAATAGAGAGTCTGAAACTTAACGGTTTCTGAAAAGTGTTCTGTTATATTAAAAGATTAAAACC
TATGAAGTAAAGTAGGGTTT

Downstream 100 bases:

>100_bases
TAAATCGGTAGATAAACAAATAGAGGACTGGTTAAGGGAATTAGGACTAGTTGCGAGTAGGCCACCCCAAGCTAAAGAAT
TCTTTCATGTCGTTGCTACT

Product: D-3-phosphoglycerate dehydrogenase, putative (serA-2)

Products: NA

Alternate protein names: PGDH [H]

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MKIISTEKVPDECKNIISVKDENITEEDYKNAEILLTWPGRVNNDLIGKMPNLKVIQTFSAGVDDLDFSIIPSHVKVFSN
AGAYSLSVAEHAWALILASAKGVGTKKRTIVYDVSEKTLLILGGGGIGSEVARIGKTAFRNYVIGISRSFKKPEWFDERH
GMTMLREKIGEADIIVDTLPLNKQTRGLLSYDLLKDIRRNAIIVNVGRGETVDEEGIYKLLKERQDVRFGTDVFWRKNGK
EDFYNTKLWELDNFTGTLHTAGAYGNESIMKRAMLIACLNVKKYIDRGIADNEVRREDYV

Sequences:

>Translated_300_residues
MKIISTEKVPDECKNIISVKDENITEEDYKNAEILLTWPGRVNNDLIGKMPNLKVIQTFSAGVDDLDFSIIPSHVKVFSN
AGAYSLSVAEHAWALILASAKGVGTKKRTIVYDVSEKTLLILGGGGIGSEVARIGKTAFRNYVIGISRSFKKPEWFDERH
GMTMLREKIGEADIIVDTLPLNKQTRGLLSYDLLKDIRRNAIIVNVGRGETVDEEGIYKLLKERQDVRFGTDVFWRKNGK
EDFYNTKLWELDNFTGTLHTAGAYGNESIMKRAMLIACLNVKKYIDRGIADNEVRREDYV
>Mature_300_residues
MKIISTEKVPDECKNIISVKDENITEEDYKNAEILLTWPGRVNNDLIGKMPNLKVIQTFSAGVDDLDFSIIPSHVKVFSN
AGAYSLSVAEHAWALILASAKGVGTKKRTIVYDVSEKTLLILGGGGIGSEVARIGKTAFRNYVIGISRSFKKPEWFDERH
GMTMLREKIGEADIIVDTLPLNKQTRGLLSYDLLKDIRRNAIIVNVGRGETVDEEGIYKLLKERQDVRFGTDVFWRKNGK
EDFYNTKLWELDNFTGTLHTAGAYGNESIMKRAMLIACLNVKKYIDRGIADNEVRREDYV

Specific function: Unknown

COG id: COG1052

COG function: function code CHR; Lactate dehydrogenase and related dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

Organism=Escherichia coli, GI87082289, Length=252, Percent_Identity=26.5873015873016, Blast_Score=76, Evalue=3e-15,
Organism=Drosophila melanogaster, GI28574286, Length=313, Percent_Identity=26.1980830670927, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR006236
- InterPro:   IPR006139
- InterPro:   IPR006140
- InterPro:   IPR015508
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00389 2-Hacid_dh; PF02826 2-Hacid_dh_C; PF01842 ACT [H]

EC number: =1.1.1.95 [H]

Molecular weight: Translated: 33812; Mature: 33812

Theoretical pI: Translated: 8.17; Mature: 8.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIISTEKVPDECKNIISVKDENITEEDYKNAEILLTWPGRVNNDLIGKMPNLKVIQTFS
CCCCCCCCCCHHHHHHHCCCCCCCCHHHCCCCEEEEECCCCCCCCHHCCCCCCEEEEEEC
AGVDDLDFSIIPSHVKVFSNAGAYSLSVAEHAWALILASAKGVGTKKRTIVYDVSEKTLL
CCCCCCCCEECHHHHHHHHCCCCEEEEHHHHHEEEEEECCCCCCCCCEEEEEEECCCEEE
ILGGGGIGSEVARIGKTAFRNYVIGISRSFKKPEWFDERHGMTMLREKIGEADIIVDTLP
EEECCCCHHHHHHHHHHHHHHHEEECCCCCCCCCCHHHHCCHHHHHHHCCCCCEEEEECC
LNKQTRGLLSYDLLKDIRRNAIIVNVGRGETVDEEGIYKLLKERQDVRFGTDVFWRKNGK
CCHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCC
EDFYNTKLWELDNFTGTLHTAGAYGNESIMKRAMLIACLNVKKYIDRGIADNEVRREDYV
CCCCCCEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCC
>Mature Secondary Structure
MKIISTEKVPDECKNIISVKDENITEEDYKNAEILLTWPGRVNNDLIGKMPNLKVIQTFS
CCCCCCCCCCHHHHHHHCCCCCCCCHHHCCCCEEEEECCCCCCCCHHCCCCCCEEEEEEC
AGVDDLDFSIIPSHVKVFSNAGAYSLSVAEHAWALILASAKGVGTKKRTIVYDVSEKTLL
CCCCCCCCEECHHHHHHHHCCCCEEEEHHHHHEEEEEECCCCCCCCCEEEEEEECCCEEE
ILGGGGIGSEVARIGKTAFRNYVIGISRSFKKPEWFDERHGMTMLREKIGEADIIVDTLP
EEECCCCHHHHHHHHHHHHHHHEEECCCCCCCCCCHHHHCCHHHHHHHCCCCCEEEEECC
LNKQTRGLLSYDLLKDIRRNAIIVNVGRGETVDEEGIYKLLKERQDVRFGTDVFWRKNGK
CCHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCC
EDFYNTKLWELDNFTGTLHTAGAYGNESIMKRAMLIACLNVKKYIDRGIADNEVRREDYV
CCCCCCEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]