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The map label for this gene is thsC [H]

Identifier: 15899709

GI number: 15899709

Start: 2740216

End: 2741835

Strand: Reverse

Name: thsC [H]

Synonym: SSO3000

Alternate gene names: 15899709

Gene position: 2741835-2740216 (Counterclockwise)

Preceding gene: 15899710

Following gene: 15899708

Centisome position: 91.63

GC content: 36.98

Gene sequence:

>1620_bases
GTGAAAGAAAACATGGCCTATTTATTAAGAGAAGGAACACAAAGATCTACTGGAAATGAGGTAATACTAAACAACATAGC
AGTAGCGAAAATATTACTAGAAATGCTAAAGTCAAGTCTAGGTCCTAAGGGCTTGGACAAAATGTTGGTTGAAGGGCAAG
ACGTTACAATAACTAATGACGGTGCTACAATAGTGAAAAACATGGAAGTACAGCATCCTACTGCTAAATTACTTATTGAA
ACCGCAAAAACTGTTGACACCGAGGTAGGGGATGGAACAACCTCAGTAGTTGTCCTCGCTGGATTACTGTTAGAAAAGGC
TGAAGACTTATTAAATCAAAAGATTCATCCAACGGTAATAATTGAAGGTTATAGGAAAGCACTAAATTCATCATTAGAAT
TGCTAAAAAATATAGCTGATAAGATTAGTCCAGAGGATAGGAAGATAGTTCACGATTTAGTATATACTACTCTTTCTAGT
AAGTTCTTCTCCACAGAGCACACTCTCGAGAAGATAATAAACTTGGTTATTGACGCTTCGTTAGCGGTATTGGATAAAAG
GGATGGAAGTTATGATCTAGATATTAAGAACATTAAGATTGTAAAGGTCAATGGCGGGGAATTCGATGATAGTGAGCTAA
TAAACGGAATCGTTGTAGATAAAGAGCCAACCAATGAGAATATGCCGAAAAGAGTGGAAAACGTTAAAGTGATGTTAGCT
GACTTTCCACTAAAACTTGAAAAAACAGAAATCAGTATGAAGTTGGGAATAAGCGATCCCACTCAGATAAAGGGATACTT
AGATGAACAAACGGCTTATGTTAAGCAAATGGTGGATAAGATAAAGGCAATGGGCGTCAAATTATTTATTACCCAAAAGG
ATATTGATGAAATTGCTTCATATTTAATGGGCAAAAATGGAATAATGGCATTAAAGAACGTAAAGAGAAGCGACATAGAA
TTATTGAGTAGGGCTACTGGTGCCAAAATTGCAAGTAGTATGAAAGATGCTAACGAAAGTGACTTAGGGGAAGCTAAATT
AGTAGAGGTTAGAAATTTAGGAAAGAACAAGTATCTCTTCATCCAATCCGATAAAGCTAAAGCAGTGACTGTAATAATAA
AGGGCTCAAATAACATGATAACTGATGAAGCAGAGAGAAGTTTAAATGACGCCTTCAACTCCATAAGAAACTTACTATTG
GAACCATATATAGTAGCGGGTGGTGGAGCAGTAGAAGAAGAGTTAGCTAAGAGATTAAGAGATGACGCAAGAAAGGTTAT
AGGAAAGGAGCAATTGGCATTTAATGCATTTGCAGATGCATTAGAAGAGTACGTTTCAATACTATCAGAAACTGCTGGTA
TGGATCCGATAAGCGCGTTAACCGAAATAAGACACAAACACGCAACTGGGTTAAAGAATGCTGGAATAGACGTTACTAAG
GCAAGGATTTACGATAATATGCTTGAACTTAGAGTGATTGACTCTCTAAAGGTTAAGGAACAAGTTTTGAAGAGTGCTAC
AGAAGCAGCTACTGCAATTTTAAAGATTGATGATATGATAGCTGCAGCTCCTGCAAAGCAACAACCTCAGCCACAACAGC
CAAACCCATACTTAGGTTAA

Upstream 100 bases:

>100_bases
GACGTAACTGAAATTCAAACTCTCCACTATTTTTATTTCACCATCCAGATACTCCGATAAAACACAAACTTTATACTTTT
CTAAACATAGTAGAGTCGGA

Downstream 100 bases:

>100_bases
AAGGTTAAGATATGATTATTTTATTTAGGTTTTCTTTATTACTTTATGGAACTAAAAATTACTGATTTCAAAGTTTTCGT
AGCTCAGGCCAATTTCGAAT

Product: thermosome subunit gamma

Products: NA

Alternate protein names: Chaperonin subunit gamma; HSP60 gamma subunit; Thermophilic factor 55 gamma; TF55-gamma; Thermosome subunit 3 [H]

Number of amino acids: Translated: 539; Mature: 539

Protein sequence:

>539_residues
MKENMAYLLREGTQRSTGNEVILNNIAVAKILLEMLKSSLGPKGLDKMLVEGQDVTITNDGATIVKNMEVQHPTAKLLIE
TAKTVDTEVGDGTTSVVVLAGLLLEKAEDLLNQKIHPTVIIEGYRKALNSSLELLKNIADKISPEDRKIVHDLVYTTLSS
KFFSTEHTLEKIINLVIDASLAVLDKRDGSYDLDIKNIKIVKVNGGEFDDSELINGIVVDKEPTNENMPKRVENVKVMLA
DFPLKLEKTEISMKLGISDPTQIKGYLDEQTAYVKQMVDKIKAMGVKLFITQKDIDEIASYLMGKNGIMALKNVKRSDIE
LLSRATGAKIASSMKDANESDLGEAKLVEVRNLGKNKYLFIQSDKAKAVTVIIKGSNNMITDEAERSLNDAFNSIRNLLL
EPYIVAGGGAVEEELAKRLRDDARKVIGKEQLAFNAFADALEEYVSILSETAGMDPISALTEIRHKHATGLKNAGIDVTK
ARIYDNMLELRVIDSLKVKEQVLKSATEAATAILKIDDMIAAAPAKQQPQPQQPNPYLG

Sequences:

>Translated_539_residues
MKENMAYLLREGTQRSTGNEVILNNIAVAKILLEMLKSSLGPKGLDKMLVEGQDVTITNDGATIVKNMEVQHPTAKLLIE
TAKTVDTEVGDGTTSVVVLAGLLLEKAEDLLNQKIHPTVIIEGYRKALNSSLELLKNIADKISPEDRKIVHDLVYTTLSS
KFFSTEHTLEKIINLVIDASLAVLDKRDGSYDLDIKNIKIVKVNGGEFDDSELINGIVVDKEPTNENMPKRVENVKVMLA
DFPLKLEKTEISMKLGISDPTQIKGYLDEQTAYVKQMVDKIKAMGVKLFITQKDIDEIASYLMGKNGIMALKNVKRSDIE
LLSRATGAKIASSMKDANESDLGEAKLVEVRNLGKNKYLFIQSDKAKAVTVIIKGSNNMITDEAERSLNDAFNSIRNLLL
EPYIVAGGGAVEEELAKRLRDDARKVIGKEQLAFNAFADALEEYVSILSETAGMDPISALTEIRHKHATGLKNAGIDVTK
ARIYDNMLELRVIDSLKVKEQVLKSATEAATAILKIDDMIAAAPAKQQPQPQQPNPYLG
>Mature_539_residues
MKENMAYLLREGTQRSTGNEVILNNIAVAKILLEMLKSSLGPKGLDKMLVEGQDVTITNDGATIVKNMEVQHPTAKLLIE
TAKTVDTEVGDGTTSVVVLAGLLLEKAEDLLNQKIHPTVIIEGYRKALNSSLELLKNIADKISPEDRKIVHDLVYTTLSS
KFFSTEHTLEKIINLVIDASLAVLDKRDGSYDLDIKNIKIVKVNGGEFDDSELINGIVVDKEPTNENMPKRVENVKVMLA
DFPLKLEKTEISMKLGISDPTQIKGYLDEQTAYVKQMVDKIKAMGVKLFITQKDIDEIASYLMGKNGIMALKNVKRSDIE
LLSRATGAKIASSMKDANESDLGEAKLVEVRNLGKNKYLFIQSDKAKAVTVIIKGSNNMITDEAERSLNDAFNSIRNLLL
EPYIVAGGGAVEEELAKRLRDDARKVIGKEQLAFNAFADALEEYVSILSETAGMDPISALTEIRHKHATGLKNAGIDVTK
ARIYDNMLELRVIDSLKVKEQVLKSATEAATAILKIDDMIAAAPAKQQPQPQQPNPYLG

Specific function: Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity [H]

COG id: COG0459

COG function: function code O; Chaperonin GroEL (HSP60 family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TCP-1 chaperonin family [H]

Homologues:

Organism=Homo sapiens, GI38455427, Length=510, Percent_Identity=40.1960784313725, Blast_Score=351, Evalue=8e-97,
Organism=Homo sapiens, GI24307939, Length=512, Percent_Identity=38.671875, Blast_Score=311, Evalue=1e-84,
Organism=Homo sapiens, GI63162572, Length=538, Percent_Identity=33.271375464684, Blast_Score=305, Evalue=9e-83,
Organism=Homo sapiens, GI5453607, Length=524, Percent_Identity=33.206106870229, Blast_Score=278, Evalue=9e-75,
Organism=Homo sapiens, GI57863257, Length=529, Percent_Identity=34.7826086956522, Blast_Score=274, Evalue=2e-73,
Organism=Homo sapiens, GI5453603, Length=504, Percent_Identity=36.1111111111111, Blast_Score=270, Evalue=2e-72,
Organism=Homo sapiens, GI58761484, Length=470, Percent_Identity=33.4042553191489, Blast_Score=266, Evalue=3e-71,
Organism=Homo sapiens, GI261399877, Length=487, Percent_Identity=32.8542094455852, Blast_Score=244, Evalue=1e-64,
Organism=Homo sapiens, GI58331173, Length=513, Percent_Identity=32.1637426900585, Blast_Score=238, Evalue=1e-62,
Organism=Homo sapiens, GI4502643, Length=513, Percent_Identity=31.9688109161793, Blast_Score=233, Evalue=4e-61,
Organism=Homo sapiens, GI302058290, Length=506, Percent_Identity=30.6324110671937, Blast_Score=203, Evalue=3e-52,
Organism=Homo sapiens, GI261399875, Length=442, Percent_Identity=30.9954751131222, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI48762932, Length=534, Percent_Identity=28.6516853932584, Blast_Score=190, Evalue=3e-48,
Organism=Homo sapiens, GI302058292, Length=513, Percent_Identity=28.4600389863548, Blast_Score=181, Evalue=2e-45,
Organism=Homo sapiens, GI58331171, Length=513, Percent_Identity=28.2651072124756, Blast_Score=176, Evalue=4e-44,
Organism=Homo sapiens, GI57863259, Length=368, Percent_Identity=30.1630434782609, Blast_Score=155, Evalue=8e-38,
Organism=Homo sapiens, GI58331185, Length=315, Percent_Identity=29.8412698412698, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI7657253, Length=516, Percent_Identity=25.3875968992248, Blast_Score=143, Evalue=5e-34,
Organism=Homo sapiens, GI25914754, Length=465, Percent_Identity=22.3655913978495, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI9055272, Length=465, Percent_Identity=22.3655913978495, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI25144674, Length=515, Percent_Identity=40, Blast_Score=328, Evalue=4e-90,
Organism=Caenorhabditis elegans, GI17532603, Length=508, Percent_Identity=36.8110236220472, Blast_Score=315, Evalue=3e-86,
Organism=Caenorhabditis elegans, GI25148561, Length=536, Percent_Identity=32.8358208955224, Blast_Score=301, Evalue=7e-82,
Organism=Caenorhabditis elegans, GI17532601, Length=533, Percent_Identity=34.7091932457786, Blast_Score=286, Evalue=2e-77,
Organism=Caenorhabditis elegans, GI25147750, Length=534, Percent_Identity=35.2059925093633, Blast_Score=283, Evalue=2e-76,
Organism=Caenorhabditis elegans, GI17564182, Length=520, Percent_Identity=31.3461538461538, Blast_Score=267, Evalue=8e-72,
Organism=Caenorhabditis elegans, GI25144678, Length=526, Percent_Identity=30.6083650190114, Blast_Score=224, Evalue=8e-59,
Organism=Caenorhabditis elegans, GI32566944, Length=442, Percent_Identity=30.7692307692308, Blast_Score=219, Evalue=4e-57,
Organism=Caenorhabditis elegans, GI71998178, Length=566, Percent_Identity=28.9752650176678, Blast_Score=213, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI25144680, Length=413, Percent_Identity=30.7506053268765, Blast_Score=196, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI71981457, Length=319, Percent_Identity=37.6175548589342, Blast_Score=186, Evalue=2e-47,
Organism=Saccharomyces cerevisiae, GI6322446, Length=520, Percent_Identity=32.8846153846154, Blast_Score=296, Evalue=7e-81,
Organism=Saccharomyces cerevisiae, GI6320058, Length=511, Percent_Identity=36.0078277886497, Blast_Score=288, Evalue=1e-78,
Organism=Saccharomyces cerevisiae, GI6322524, Length=522, Percent_Identity=34.2911877394636, Blast_Score=280, Evalue=3e-76,
Organism=Saccharomyces cerevisiae, GI6322350, Length=521, Percent_Identity=33.5892514395393, Blast_Score=263, Evalue=4e-71,
Organism=Saccharomyces cerevisiae, GI6322049, Length=507, Percent_Identity=34.7140039447732, Blast_Score=263, Evalue=7e-71,
Organism=Saccharomyces cerevisiae, GI6320418, Length=550, Percent_Identity=32, Blast_Score=258, Evalue=2e-69,
Organism=Saccharomyces cerevisiae, GI6320393, Length=532, Percent_Identity=28.1954887218045, Blast_Score=193, Evalue=6e-50,
Organism=Saccharomyces cerevisiae, GI6322452, Length=556, Percent_Identity=26.6187050359712, Blast_Score=186, Evalue=6e-48,
Organism=Saccharomyces cerevisiae, GI6321131, Length=172, Percent_Identity=26.1627906976744, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24583944, Length=514, Percent_Identity=37.9377431906615, Blast_Score=332, Evalue=5e-91,
Organism=Drosophila melanogaster, GI17647245, Length=519, Percent_Identity=36.6088631984586, Blast_Score=291, Evalue=7e-79,
Organism=Drosophila melanogaster, GI24647512, Length=536, Percent_Identity=33.7686567164179, Blast_Score=290, Evalue=2e-78,
Organism=Drosophila melanogaster, GI24647510, Length=536, Percent_Identity=33.7686567164179, Blast_Score=290, Evalue=2e-78,
Organism=Drosophila melanogaster, GI24652903, Length=508, Percent_Identity=36.8110236220472, Blast_Score=285, Evalue=4e-77,
Organism=Drosophila melanogaster, GI18858175, Length=538, Percent_Identity=34.3866171003717, Blast_Score=280, Evalue=2e-75,
Organism=Drosophila melanogaster, GI28571140, Length=538, Percent_Identity=34.2007434944238, Blast_Score=280, Evalue=3e-75,
Organism=Drosophila melanogaster, GI24649027, Length=532, Percent_Identity=35.7142857142857, Blast_Score=279, Evalue=4e-75,
Organism=Drosophila melanogaster, GI24649029, Length=532, Percent_Identity=35.7142857142857, Blast_Score=279, Evalue=4e-75,
Organism=Drosophila melanogaster, GI24645179, Length=527, Percent_Identity=33.0170777988615, Blast_Score=259, Evalue=4e-69,
Organism=Drosophila melanogaster, GI19921848, Length=528, Percent_Identity=29.5454545454545, Blast_Score=207, Evalue=2e-53,
Organism=Drosophila melanogaster, GI18859933, Length=510, Percent_Identity=29.2156862745098, Blast_Score=202, Evalue=4e-52,

Paralogues:

None

Copy number: 2180 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 480 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 15012 Molecules/Cell In: Growth Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017998
- InterPro:   IPR002194
- InterPro:   IPR002423
- InterPro:   IPR012714 [H]

Pfam domain/function: PF00118 Cpn60_TCP1 [H]

EC number: NA

Molecular weight: Translated: 59273; Mature: 59273

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS00750 TCP1_1 ; PS00751 TCP1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKENMAYLLREGTQRSTGNEVILNNIAVAKILLEMLKSSLGPKGLDKMLVEGQDVTITND
CCCCHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCEEEECC
GATIVKNMEVQHPTAKLLIETAKTVDTEVGDGTTSVVVLAGLLLEKAEDLLNQKIHPTVI
CCEEEECCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEE
IEGYRKALNSSLELLKNIADKISPEDRKIVHDLVYTTLSSKFFSTEHTLEKIINLVIDAS
EHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAVLDKRDGSYDLDIKNIKIVKVNGGEFDDSELINGIVVDKEPTNENMPKRVENVKVMLA
HHEEECCCCCEEEEECEEEEEEECCCCCCHHHHHCCEEECCCCCCCCCHHHHHHHEEEEE
DFPLKLEKTEISMKLGISDPTQIKGYLDEQTAYVKQMVDKIKAMGVKLFITQKDIDEIAS
CCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHH
YLMGKNGIMALKNVKRSDIELLSRATGAKIASSMKDANESDLGEAKLVEVRNLGKNKYLF
HHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCEEEE
IQSDKAKAVTVIIKGSNNMITDEAERSLNDAFNSIRNLLLEPYIVAGGGAVEEELAKRLR
EECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHH
DDARKVIGKEQLAFNAFADALEEYVSILSETAGMDPISALTEIRHKHATGLKNAGIDVTK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCHHH
ARIYDNMLELRVIDSLKVKEQVLKSATEAATAILKIDDMIAAAPAKQQPQPQQPNPYLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKENMAYLLREGTQRSTGNEVILNNIAVAKILLEMLKSSLGPKGLDKMLVEGQDVTITND
CCCCHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCEEEECC
GATIVKNMEVQHPTAKLLIETAKTVDTEVGDGTTSVVVLAGLLLEKAEDLLNQKIHPTVI
CCEEEECCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEE
IEGYRKALNSSLELLKNIADKISPEDRKIVHDLVYTTLSSKFFSTEHTLEKIINLVIDAS
EHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAVLDKRDGSYDLDIKNIKIVKVNGGEFDDSELINGIVVDKEPTNENMPKRVENVKVMLA
HHEEECCCCCEEEEECEEEEEEECCCCCCHHHHHCCEEECCCCCCCCCHHHHHHHEEEEE
DFPLKLEKTEISMKLGISDPTQIKGYLDEQTAYVKQMVDKIKAMGVKLFITQKDIDEIAS
CCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHH
YLMGKNGIMALKNVKRSDIELLSRATGAKIASSMKDANESDLGEAKLVEVRNLGKNKYLF
HHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCEEEE
IQSDKAKAVTVIIKGSNNMITDEAERSLNDAFNSIRNLLLEPYIVAGGGAVEEELAKRLR
EECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHH
DDARKVIGKEQLAFNAFADALEEYVSILSETAGMDPISALTEIRHKHATGLKNAGIDVTK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCHHH
ARIYDNMLELRVIDSLKVKEQVLKSATEAATAILKIDDMIAAAPAKQQPQPQQPNPYLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10508614 [H]