Click here to switch to the map view.

The map label for this gene is dgoD [H]

Identifier: 15899708

GI number: 15899708

Start: 2738911

End: 2740170

Strand: Reverse

Name: dgoD [H]

Synonym: SSO2998

Alternate gene names: 15899708

Gene position: 2740170-2738911 (Counterclockwise)

Preceding gene: 15899709

Following gene: 15899706

Centisome position: 91.58

GC content: 39.37

Gene sequence:

>1260_bases
ATGGAACTAAAAATTACTGATTTCAAAGTTTTCGTAGCTCAGGCCAATTTCGAATGGGCTTTTGTGAGAATCTACTCCAA
AGACTTATATGGTACTGGTGAGGCAGGTCCTGCGCCAGGTTTAAAGGGAATGGAAAGCGAGTTTATACAATTACTAATTG
GAGAAGACGCATTCAAAGTTAATAGGATAGCTGAGAAACTCAGGTACGCTACACTATACTCTGGAACTACTGTATATCAC
TTGATCTCAGCCATTAATATTGCACTGTACGATCTTATTGGGAAATACCTAAATGTACCAATATACAAATTACTAGGTGG
GGATAAGACGGAAATACCAGTCTATGTCGACGCTCATGGAGGGAAAGGGTTAGAAGCAATTAATGCTTTACACTTACCAG
TTAATTTACCTTGGATCAAGGAGGCTGAGGTGGAGACAAATAGGTTGATCACAACCAATAATCCAGTTCATGGTAGGTTA
TCAATGGAAAAGTGGAATGAAGATTATTCACCTGAGGCATACGCTAAGAGAGCTCTAAAGATGAAGAACGAGGGTTATAA
AGCCATGAAATTTGATCTAGACGTACCTACACCTTATATAGATTTAAGGAGAGTAAGAAATGGAGATTTATCTCTTAAAG
ATATCGACTACATGGTAGATATAGTAAAGGCAGTTAGAGAGTCCGTTGGCGATGAGGTCGAAATAATGTTCGATTTGCAT
TGGAGATATAATTTAAATACTGCAATTAGGATTTGTAAGGCACTAGAACCATATAGACTAAGATGGCTAGAGGATCCAAT
GCCGGCAATAATGGCTGTTTCCAATTACGACGAGTTAAAGTTGTTGACCTCTCAGTGTTCAGTTCCGATAGAGACTGGCG
AGAACCTCTATACAGTATATCAGTTCAAGGATTTGCTCAATACTGGAGTTAGAGTGTGGGCTCCGGATATAGTTAAAGCT
GGTGGAATAACCGAGGGAAGGAGAATAGCTGAATTAGCTGCCATGTATGATATAGAATACTCTCCTCATAATATAGCATC
ACCAATAGGTACTATGGCTCATGCCCATGTAGGGTCAATTGCAAACACATTCGGTTTTGTGGAATTTCATGGTCACGATG
TACCATTTTGGAATGAGATCGTTAAGCCGAAGAGAAAGATTATAGAAGATGGTGTGATTAAGCTTACCGATGACCCTGGA
TTGGGCATAGATCTAGACGATGAGGTAATGAGAAAATATTGGCCAACTTATGAGTTATGA

Upstream 100 bases:

>100_bases
AGCTCCTGCAAAGCAACAACCTCAGCCACAACAGCCAAACCCATACTTAGGTTAAAAGGTTAAGATATGATTATTTTATT
TAGGTTTTCTTTATTACTTT

Downstream 100 bases:

>100_bases
ACATACCAAAGAAATGAGATTTTCTCCTCCTTTAACTCACTGGAAGTTATGATAGGAAAAAACTCACATATAGAAACCTT
TACTTGTATTTATTAACTCC

Product: hypothetical protein

Products: NA

Alternate protein names: GalD [H]

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MELKITDFKVFVAQANFEWAFVRIYSKDLYGTGEAGPAPGLKGMESEFIQLLIGEDAFKVNRIAEKLRYATLYSGTTVYH
LISAINIALYDLIGKYLNVPIYKLLGGDKTEIPVYVDAHGGKGLEAINALHLPVNLPWIKEAEVETNRLITTNNPVHGRL
SMEKWNEDYSPEAYAKRALKMKNEGYKAMKFDLDVPTPYIDLRRVRNGDLSLKDIDYMVDIVKAVRESVGDEVEIMFDLH
WRYNLNTAIRICKALEPYRLRWLEDPMPAIMAVSNYDELKLLTSQCSVPIETGENLYTVYQFKDLLNTGVRVWAPDIVKA
GGITEGRRIAELAAMYDIEYSPHNIASPIGTMAHAHVGSIANTFGFVEFHGHDVPFWNEIVKPKRKIIEDGVIKLTDDPG
LGIDLDDEVMRKYWPTYEL

Sequences:

>Translated_419_residues
MELKITDFKVFVAQANFEWAFVRIYSKDLYGTGEAGPAPGLKGMESEFIQLLIGEDAFKVNRIAEKLRYATLYSGTTVYH
LISAINIALYDLIGKYLNVPIYKLLGGDKTEIPVYVDAHGGKGLEAINALHLPVNLPWIKEAEVETNRLITTNNPVHGRL
SMEKWNEDYSPEAYAKRALKMKNEGYKAMKFDLDVPTPYIDLRRVRNGDLSLKDIDYMVDIVKAVRESVGDEVEIMFDLH
WRYNLNTAIRICKALEPYRLRWLEDPMPAIMAVSNYDELKLLTSQCSVPIETGENLYTVYQFKDLLNTGVRVWAPDIVKA
GGITEGRRIAELAAMYDIEYSPHNIASPIGTMAHAHVGSIANTFGFVEFHGHDVPFWNEIVKPKRKIIEDGVIKLTDDPG
LGIDLDDEVMRKYWPTYEL
>Mature_419_residues
MELKITDFKVFVAQANFEWAFVRIYSKDLYGTGEAGPAPGLKGMESEFIQLLIGEDAFKVNRIAEKLRYATLYSGTTVYH
LISAINIALYDLIGKYLNVPIYKLLGGDKTEIPVYVDAHGGKGLEAINALHLPVNLPWIKEAEVETNRLITTNNPVHGRL
SMEKWNEDYSPEAYAKRALKMKNEGYKAMKFDLDVPTPYIDLRRVRNGDLSLKDIDYMVDIVKAVRESVGDEVEIMFDLH
WRYNLNTAIRICKALEPYRLRWLEDPMPAIMAVSNYDELKLLTSQCSVPIETGENLYTVYQFKDLLNTGVRVWAPDIVKA
GGITEGRRIAELAAMYDIEYSPHNIASPIGTMAHAHVGSIANTFGFVEFHGHDVPFWNEIVKPKRKIIEDGVIKLTDDPG
LGIDLDDEVMRKYWPTYEL

Specific function: Catalyzes the dehydration of D-galactonate to 2-keto-3- deoxy-D-galactonate [H]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787864, Length=428, Percent_Identity=26.6355140186916, Blast_Score=118, Evalue=6e-28,
Organism=Escherichia coli, GI48994953, Length=201, Percent_Identity=30.3482587064677, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI226510960, Length=204, Percent_Identity=27.9411764705882, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018110
- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =4.2.1.6 [H]

Molecular weight: Translated: 47589; Mature: 47589

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS00909 MR_MLE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELKITDFKVFVAQANFEWAFVRIYSKDLYGTGEAGPAPGLKGMESEFIQLLIGEDAFKV
CCEEEEEEEEEEEECCCCEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHH
NRIAEKLRYATLYSGTTVYHLISAINIALYDLIGKYLNVPIYKLLGGDKTEIPVYVDAHG
HHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCEEEECCC
GKGLEAINALHLPVNLPWIKEAEVETNRLITTNNPVHGRLSMEKWNEDYSPEAYAKRALK
CCCCHHHEEEECCCCCCCCCCCCCCCCEEEECCCCCCEEEEHHHCCCCCCHHHHHHHHHH
MKNEGYKAMKFDLDVPTPYIDLRRVRNGDLSLKDIDYMVDIVKAVRESVGDEVEIMFDLH
HCCCCCEEEEEECCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEE
WRYNLNTAIRICKALEPYRLRWLEDPMPAIMAVSNYDELKLLTSQCSVPIETGENLYTVY
EEECCHHHHHHHHHCCCHHHHCCCCCCCCEEEECCCHHHHHHHHHCCCEECCCCCEEEHH
QFKDLLNTGVRVWAPDIVKAGGITEGRRIAELAAMYDIEYSPHNIASPIGTMAHAHVGSI
HHHHHHHCCCEEECCHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHCHHHHHHHHHHHHH
ANTFGFVEFHGHDVPFWNEIVKPKRKIIEDGVIKLTDDPGLGIDLDDEVMRKYWPTYEL
HHHCEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHCCCCCC
>Mature Secondary Structure
MELKITDFKVFVAQANFEWAFVRIYSKDLYGTGEAGPAPGLKGMESEFIQLLIGEDAFKV
CCEEEEEEEEEEEECCCCEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHH
NRIAEKLRYATLYSGTTVYHLISAINIALYDLIGKYLNVPIYKLLGGDKTEIPVYVDAHG
HHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCEEEECCC
GKGLEAINALHLPVNLPWIKEAEVETNRLITTNNPVHGRLSMEKWNEDYSPEAYAKRALK
CCCCHHHEEEECCCCCCCCCCCCCCCCEEEECCCCCCEEEEHHHCCCCCCHHHHHHHHHH
MKNEGYKAMKFDLDVPTPYIDLRRVRNGDLSLKDIDYMVDIVKAVRESVGDEVEIMFDLH
HCCCCCEEEEEECCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEE
WRYNLNTAIRICKALEPYRLRWLEDPMPAIMAVSNYDELKLLTSQCSVPIETGENLYTVY
EEECCHHHHHHHHHCCCHHHHCCCCCCCCEEEECCCHHHHHHHHHCCCEECCCCCEEEHH
QFKDLLNTGVRVWAPDIVKAGGITEGRRIAELAAMYDIEYSPHNIASPIGTMAHAHVGSI
HHHHHHHCCCEEECCHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHCHHHHHHHHHHHHH
ANTFGFVEFHGHDVPFWNEIVKPKRKIIEDGVIKLTDDPGLGIDLDDEVMRKYWPTYEL
HHHCEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA