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The map label for this gene is mvk [H]

Identifier: 15899698

GI number: 15899698

Start: 2730848

End: 2731819

Strand: Direct

Name: mvk [H]

Synonym: SSO2988

Alternate gene names: 15899698

Gene position: 2730848-2731819 (Clockwise)

Preceding gene: 15899694

Following gene: 15899701

Centisome position: 91.26

GC content: 36.52

Gene sequence:

>972_bases
GTGATAAAGGTTAGCGCACCTGGCAAAATACTTTGGATAGGAAGTTACAGCGTAGTTTTTGGAGGCATATCACATGTAAT
AGCAGTTAATAAGAGAGTGAGTTGTAGTTTGAGAGAAATTAAAGAGAAGGATAGTTTAATTTTCCATACTAGTTATGGGC
ACTTCAAAAATTCTGGTAATGAGTTAATTAATTCAGTCCTAGATACTTTTAGAGAAAGGCTTTCACAACTTCCTCAAGGT
TATGAAATAGATCTATATAACGATAAGGAGTTTATAATAGATGGTAAAAAAACGGGACTAGGTAGTTCTTCGGCTGCTAC
AGTTTCCCTTACCGCTTGTCTGTATTACGCTATCCACGGCAAACTGGATTTGTTTGAGATACATAAATTGGCACAAATTG
CCAACTATAAGAGACAAAAGGGAATTGGTAGTGGGTTTGACATAGCTTCAGCTGTTTTTGGTAGCATAGTTTACAAGAGA
TTTACTGATTTAGATAAGATGGACTTCTATTTCGAAAAACTCAATTTGGGAAATTACGATATGATGCTTGGATTTACGGG
AAAGAGTTCTGAAACCGTGGGTTTGGTTAGGAAATTTGTAGAGAAGAGTAATTTGGATGATTTTAAGGAAATAATGAGGC
TTATAGATGAGGAGAATTATATGGCAATCAAACTCATAAAATTGAATAAGCTTGACGAGGCTGTGGAGCACATAAAGTTA
GGAAGGAAGTATTTGAATTATATAGCTGAGCGTATTGTTGGTGTTAAACTGGTAAGTAAAATGGAGGAGGAGTTGATAAA
AATAGCAGAAGAGGAAGGTGCGTTAGTAGCCTTATCTCCTGGGGCAGGTGGGGGAGATTCAATTTTTGCATTAGGCAATG
ATTTAAATAGGGTAAGGGAGGCGTGGAGTAAAAGAGGTATTTTCATAATTGATGTGAAAGAAGACGAGGGATTAAGGCTC
GAATCTAACTAA

Upstream 100 bases:

>100_bases
GGGCTATTGCAACTAATACTAACCTTTCCCTCTTGCTTAGAAATTCCATTTGGAAATGAATAGTAGTTAAAGATTAAAAA
GCTAATAAGGAATATGGAAT

Downstream 100 bases:

>100_bases
ATTTTCATTCTCTACTTAATACTTTTGGTCCATCTCCTACTTTAGATACTATTATTCTCTTTATTTCTAGAGATTTTAAG
AATTCTAAAATATCTCCTAT

Product: (phospho) mevalonate kinase, putative

Products: NA

Alternate protein names: MK [H]

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MIKVSAPGKILWIGSYSVVFGGISHVIAVNKRVSCSLREIKEKDSLIFHTSYGHFKNSGNELINSVLDTFRERLSQLPQG
YEIDLYNDKEFIIDGKKTGLGSSSAATVSLTACLYYAIHGKLDLFEIHKLAQIANYKRQKGIGSGFDIASAVFGSIVYKR
FTDLDKMDFYFEKLNLGNYDMMLGFTGKSSETVGLVRKFVEKSNLDDFKEIMRLIDEENYMAIKLIKLNKLDEAVEHIKL
GRKYLNYIAERIVGVKLVSKMEEELIKIAEEEGALVALSPGAGGGDSIFALGNDLNRVREAWSKRGIFIIDVKEDEGLRL
ESN

Sequences:

>Translated_323_residues
MIKVSAPGKILWIGSYSVVFGGISHVIAVNKRVSCSLREIKEKDSLIFHTSYGHFKNSGNELINSVLDTFRERLSQLPQG
YEIDLYNDKEFIIDGKKTGLGSSSAATVSLTACLYYAIHGKLDLFEIHKLAQIANYKRQKGIGSGFDIASAVFGSIVYKR
FTDLDKMDFYFEKLNLGNYDMMLGFTGKSSETVGLVRKFVEKSNLDDFKEIMRLIDEENYMAIKLIKLNKLDEAVEHIKL
GRKYLNYIAERIVGVKLVSKMEEELIKIAEEEGALVALSPGAGGGDSIFALGNDLNRVREAWSKRGIFIIDVKEDEGLRL
ESN
>Mature_323_residues
MIKVSAPGKILWIGSYSVVFGGISHVIAVNKRVSCSLREIKEKDSLIFHTSYGHFKNSGNELINSVLDTFRERLSQLPQG
YEIDLYNDKEFIIDGKKTGLGSSSAATVSLTACLYYAIHGKLDLFEIHKLAQIANYKRQKGIGSGFDIASAVFGSIVYKR
FTDLDKMDFYFEKLNLGNYDMMLGFTGKSSETVGLVRKFVEKSNLDDFKEIMRLIDEENYMAIKLIKLNKLDEAVEHIKL
GRKYLNYIAERIVGVKLVSKMEEELIKIAEEEGALVALSPGAGGGDSIFALGNDLNRVREAWSKRGIFIIDVKEDEGLRL
ESN

Specific function: Unknown

COG id: COG3890

COG function: function code I; Phosphomevalonate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GHMP kinase family. Mevalonate kinase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006204
- InterPro:   IPR013750
- InterPro:   IPR006203
- InterPro:   IPR006205
- InterPro:   IPR006206
- InterPro:   IPR022937
- InterPro:   IPR020568
- InterPro:   IPR014721 [H]

Pfam domain/function: PF08544 GHMP_kinases_C; PF00288 GHMP_kinases_N [H]

EC number: =2.7.1.36 [H]

Molecular weight: Translated: 36208; Mature: 36208

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKVSAPGKILWIGSYSVVFGGISHVIAVNKRVSCSLREIKEKDSLIFHTSYGHFKNSGN
CEEECCCCCEEEEECHHHHHHHHHHHHEECCCCCHHHHHHHCCCCEEEEECCCCCCCCHH
ELINSVLDTFRERLSQLPQGYEIDLYNDKEFIIDGKKTGLGSSSAATVSLTACLYYAIHG
HHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCC
KLDLFEIHKLAQIANYKRQKGIGSGFDIASAVFGSIVYKRFTDLDKMDFYFEKLNLGNYD
CCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEE
MMLGFTGKSSETVGLVRKFVEKSNLDDFKEIMRLIDEENYMAIKLIKLNKLDEAVEHIKL
EEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEEEHHHHHHHHHHHHH
GRKYLNYIAERIVGVKLVSKMEEELIKIAEEEGALVALSPGAGGGDSIFALGNDLNRVRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEECCHHHHHHH
AWSKRGIFIIDVKEDEGLRLESN
HHHHCCEEEEEECCCCCCEECCC
>Mature Secondary Structure
MIKVSAPGKILWIGSYSVVFGGISHVIAVNKRVSCSLREIKEKDSLIFHTSYGHFKNSGN
CEEECCCCCEEEEECHHHHHHHHHHHHEECCCCCHHHHHHHCCCCEEEEECCCCCCCCHH
ELINSVLDTFRERLSQLPQGYEIDLYNDKEFIIDGKKTGLGSSSAATVSLTACLYYAIHG
HHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCC
KLDLFEIHKLAQIANYKRQKGIGSGFDIASAVFGSIVYKRFTDLDKMDFYFEKLNLGNYD
CCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEE
MMLGFTGKSSETVGLVRKFVEKSNLDDFKEIMRLIDEENYMAIKLIKLNKLDEAVEHIKL
EEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEEEHHHHHHHHHHHHH
GRKYLNYIAERIVGVKLVSKMEEELIKIAEEEGALVALSPGAGGGDSIFALGNDLNRVRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEECCHHHHHHH
AWSKRGIFIIDVKEDEGLRLESN
HHHHCCEEEEEECCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]