BacMap

Definition	Sulfolobus solfataricus P2 chromosome, complete genome.
Accession	NC_002754
Length	2,992,245

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The map label for this gene is yhdN [H]

Identifier: 15899596

GI number: 15899596

Start: 2638613

End: 2639527

Strand: Reverse

Name: yhdN [H]

Synonym: SSO2885

Alternate gene names: 15899596

Gene position: 2639527-2638613 (Counterclockwise)

Preceding gene: 15899598

Following gene: 15899595

Centisome position: 88.21

GC content: 37.38

Gene sequence:

>915_bases
ATGGAAAAGAAGCCATTAGGATGGACGAATGAGAAAATATCCCCCTTAATCTTAGGTTCTTGGGAATTTGGTACACCTTC
AATAATCGACGAGAATAATGCAATAAAAGCTATTCAAAGGGCAATAGAGCTTGGAATAAACGCAATAGACACTGCCGAAT
CCTATGGAAATGGTCTTTCAGAAACAATTATTGGAAGAGCCATAAGTAAATTCAAGAGAGAAGATTTGTTCATAATAACT
AAAGTATCAATTGACCACTTAAGATATGATGACGTTTTGAAGGCTTCTGAGGGAAGTTTAAAAAGACTTAACACATCATA
TATAGACTTATACCTAGTTCACTGGCCTAATCACTATGTGCCCATAAGGGAAACTGCTAAGGCGATGGAGAGGTTATTCA
ACGAGGGAAAAATTAGATATGTTGGCCTAAGTAACTTTTCCCTTCCCTTGATGAGGGAATTTAGAGAACATTTATCTAAG
ACTGACGTTGCGGCTAATGAATTGCATTATAACGTTCTATTTAGAGACGTAGAGAAGGAGGTTCTTCCTTATATGTTAAG
GGAAAATATCCCCTTGCTAGCATACGATGCTTTAGGATTAGGTTATCTAATAGGGAGAAAGGAGGTCAGAAACGAGTACA
GATGGTATGTCCTTGCTAGGGAGACTTACATTAAAAACTTAGAACCGCTCATAGAGGAAATATCTTCAATTGCTAAGGAA
CTAGGTAAAACTCCAGCACAAGTAGTTCTAAATTGGTTGGTCAGTAAGGATAATGTATTTGCTATCTTCAACACTACTAA
AGAGGATCACCTCAAGGAGAATTTAGGAAGTCTAGGATGGTCGCTTAGGGATAGCGACTTAAGGAGATTAGATGAAGCAG
TAAAAAAAGTCACGATAGATTATTTCGCAAGGTAA

Upstream 100 bases:

>100_bases
CTCCATAAGAATTAGTATGTTAGTCAAAATTAAAAGAAAATTGGTCTAGGCTAAACTCAATTAATAAACATTTAAATACT
TAACAATATCTTACTTATTC

Downstream 100 bases:

>100_bases
TCCGAGTCCCTCTTCTTTACCAGATCGCTTTTTTATCTTAATATTAATCAAATATTATATGGGTAGTCTGTTCGACAAAG
ACCCGGAATTAAAGAAGCTC

Product: oxidoreductase

Products: NA

Alternate protein names: GSP69; AKR11B [H]

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MEKKPLGWTNEKISPLILGSWEFGTPSIIDENNAIKAIQRAIELGINAIDTAESYGNGLSETIIGRAISKFKREDLFIIT
KVSIDHLRYDDVLKASEGSLKRLNTSYIDLYLVHWPNHYVPIRETAKAMERLFNEGKIRYVGLSNFSLPLMREFREHLSK
TDVAANELHYNVLFRDVEKEVLPYMLRENIPLLAYDALGLGYLIGRKEVRNEYRWYVLARETYIKNLEPLIEEISSIAKE
LGKTPAQVVLNWLVSKDNVFAIFNTTKEDHLKENLGSLGWSLRDSDLRRLDEAVKKVTIDYFAR

Sequences:

>Translated_304_residues
MEKKPLGWTNEKISPLILGSWEFGTPSIIDENNAIKAIQRAIELGINAIDTAESYGNGLSETIIGRAISKFKREDLFIIT
KVSIDHLRYDDVLKASEGSLKRLNTSYIDLYLVHWPNHYVPIRETAKAMERLFNEGKIRYVGLSNFSLPLMREFREHLSK
TDVAANELHYNVLFRDVEKEVLPYMLRENIPLLAYDALGLGYLIGRKEVRNEYRWYVLARETYIKNLEPLIEEISSIAKE
LGKTPAQVVLNWLVSKDNVFAIFNTTKEDHLKENLGSLGWSLRDSDLRRLDEAVKKVTIDYFAR
>Mature_304_residues
MEKKPLGWTNEKISPLILGSWEFGTPSIIDENNAIKAIQRAIELGINAIDTAESYGNGLSETIIGRAISKFKREDLFIIT
KVSIDHLRYDDVLKASEGSLKRLNTSYIDLYLVHWPNHYVPIRETAKAMERLFNEGKIRYVGLSNFSLPLMREFREHLSK
TDVAANELHYNVLFRDVEKEVLPYMLRENIPLLAYDALGLGYLIGRKEVRNEYRWYVLARETYIKNLEPLIEEISSIAKE
LGKTPAQVVLNWLVSKDNVFAIFNTTKEDHLKENLGSLGWSLRDSDLRRLDEAVKKVTIDYFAR

Specific function: Unknown

COG id: COG0656

COG function: function code R; Aldo/keto reductases, related to diketogulonate reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=299, Percent_Identity=25.4180602006689, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI4504825, Length=299, Percent_Identity=25.4180602006689, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI27436966, Length=303, Percent_Identity=25.0825082508251, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI27436964, Length=303, Percent_Identity=25.0825082508251, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI27436962, Length=303, Percent_Identity=25.0825082508251, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI310109922, Length=296, Percent_Identity=27.3648648648649, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI45446745, Length=315, Percent_Identity=26.3492063492064, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI4503285, Length=315, Percent_Identity=26.3492063492064, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI310109920, Length=315, Percent_Identity=26.3492063492064, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI5453543, Length=318, Percent_Identity=26.1006289308176, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI223718702, Length=199, Percent_Identity=31.6582914572864, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI24497577, Length=313, Percent_Identity=24.6006389776358, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI5174391, Length=313, Percent_Identity=24.6006389776358, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI41327764, Length=199, Percent_Identity=32.6633165829146, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI41152114, Length=203, Percent_Identity=30.5418719211823, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI24497585, Length=305, Percent_Identity=26.2295081967213, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI24497583, Length=303, Percent_Identity=25.7425742574257, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI223468663, Length=305, Percent_Identity=25.2459016393443, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI223718708, Length=136, Percent_Identity=35.2941176470588, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI291291012, Length=278, Percent_Identity=26.2589928057554, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI27436971, Length=305, Percent_Identity=22.9508196721311, Blast_Score=73, Evalue=3e-13,
Organism=Escherichia coli, GI87081735, Length=330, Percent_Identity=30.9090909090909, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1788081, Length=294, Percent_Identity=30.952380952381, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1788070, Length=332, Percent_Identity=29.2168674698795, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1786400, Length=260, Percent_Identity=30, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1789199, Length=338, Percent_Identity=31.0650887573964, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789375, Length=310, Percent_Identity=27.4193548387097, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI87082198, Length=244, Percent_Identity=30.327868852459, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI48994888, Length=263, Percent_Identity=24.3346007604563, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17564128, Length=301, Percent_Identity=28.2392026578073, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI212645785, Length=162, Percent_Identity=33.9506172839506, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17552492, Length=294, Percent_Identity=27.2108843537415, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17550248, Length=298, Percent_Identity=27.1812080536913, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17566692, Length=300, Percent_Identity=27.3333333333333, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17537077, Length=279, Percent_Identity=29.3906810035842, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17537075, Length=279, Percent_Identity=29.0322580645161, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17561300, Length=193, Percent_Identity=30.0518134715026, Blast_Score=68, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6325169, Length=333, Percent_Identity=25.2252252252252, Blast_Score=102, Evalue=8e-23,
Organism=Saccharomyces cerevisiae, GI6323998, Length=316, Percent_Identity=26.5822784810127, Blast_Score=95, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6319958, Length=292, Percent_Identity=25, Blast_Score=85, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6319951, Length=319, Percent_Identity=26.6457680250784, Blast_Score=83, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6324694, Length=298, Percent_Identity=27.8523489932886, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6321896, Length=297, Percent_Identity=24.9158249158249, Blast_Score=72, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6320079, Length=269, Percent_Identity=22.6765799256506, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322615, Length=251, Percent_Identity=24.3027888446215, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319625, Length=202, Percent_Identity=30.6930693069307, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24646155, Length=216, Percent_Identity=30.5555555555556, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI45553081, Length=280, Percent_Identity=27.1428571428571, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24662789, Length=315, Percent_Identity=24.7619047619048, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24646159, Length=188, Percent_Identity=30.3191489361702, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI281366140, Length=273, Percent_Identity=26.7399267399267, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24657054, Length=292, Percent_Identity=24.3150684931507, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI20129731, Length=305, Percent_Identity=23.9344262295082, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR018170
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35081; Mature: 35081

Theoretical pI: Translated: 6.82; Mature: 6.82

Prosite motif: PS00062 ALDOKETO_REDUCTASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKKPLGWTNEKISPLILGSWEFGTPSIIDENNAIKAIQRAIELGINAIDTAESYGNGLS
CCCCCCCCCCCCCCEEEEECCCCCCCCEECCCHHHHHHHHHHHHCCCHHHHHHHHCCCHH
ETIIGRAISKFKREDLFIITKVSIDHLRYDDVLKASEGSLKRLNTSYIDLYLVHWPNHYV
HHHHHHHHHHHCCCCEEEEEEEEHHHHHHHHHHHCCCCCHHHCCCCEEEEEEEECCCCCC
PIRETAKAMERLFNEGKIRYVGLSNFSLPLMREFREHLSKTDVAANELHYNVLFRDVEKE
CHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
VLPYMLRENIPLLAYDALGLGYLIGRKEVRNEYRWYVLARETYIKNLEPLIEEISSIAKE
HHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHH
LGKTPAQVVLNWLVSKDNVFAIFNTTKEDHLKENLGSLGWSLRDSDLRRLDEAVKKVTID
HCCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
YFAR
HHCC
>Mature Secondary Structure
MEKKPLGWTNEKISPLILGSWEFGTPSIIDENNAIKAIQRAIELGINAIDTAESYGNGLS
CCCCCCCCCCCCCCEEEEECCCCCCCCEECCCHHHHHHHHHHHHCCCHHHHHHHHCCCHH
ETIIGRAISKFKREDLFIITKVSIDHLRYDDVLKASEGSLKRLNTSYIDLYLVHWPNHYV
HHHHHHHHHHHCCCCEEEEEEEEHHHHHHHHHHHCCCCCHHHCCCCEEEEEEEECCCCCC
PIRETAKAMERLFNEGKIRYVGLSNFSLPLMREFREHLSKTDVAANELHYNVLFRDVEKE
CHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
VLPYMLRENIPLLAYDALGLGYLIGRKEVRNEYRWYVLARETYIKNLEPLIEEISSIAKE
HHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHH
LGKTPAQVVLNWLVSKDNVFAIFNTTKEDHLKENLGSLGWSLRDSDLRRLDEAVKKVTID
HCCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
YFAR
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 9298659 [H]