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The map label for this gene is alkK-3 [H]

Identifier: 15899525

GI number: 15899525

Start: 2568807

End: 2570330

Strand: Direct

Name: alkK-3 [H]

Synonym: SSO2808

Alternate gene names: 15899525

Gene position: 2568807-2570330 (Clockwise)

Preceding gene: 15899523

Following gene: 15899526

Centisome position: 85.85

GC content: 39.11

Gene sequence:

>1524_bases
ATGGATTCAACAATAATGGACTACAATCTCAATATAAGGTCTATATTTTGGAGAATAGAAAAACTATATAAAGATAGGGA
GATTATATCTAGAACGTATGAGGGGATAGTTCATTACACATATTCTGATTTCGCATTAAGGGTTAGGAAGCTAGCGACTT
TCTTGAAGACTAATGGTATAGCGGGAGAAGCAGTTGCCTCAATAGCGTGGAATACTCATAGACACTTGGAGTTATACTTT
GCAGTTCCTTTATTAGGTGGAGTCTTGCATACAGTTAATGTAAGGTTTCATGAGTCTGAAATGGATTACGTAATTAAATC
AATGGGAGACAAAGCGATATTCATGGACAAGGATATAAATTACAAGAATTCCACCTTACCCACTTTCATTTTTGATGAAA
GGTATGATGAAGATGTAAATTCACAAGAATCGACTAGTGATTTTCCTGATGTAGATGAAAGGCAAGGTGCCATAGCTTGC
TTTACCTCAGGTACAACTGGAAAGCCTAAGGGAGTCATATATAGCCATAGGAGTGTATTTATCCACTCACTATCACTATT
AGCTGCTGACGCACTAGGTATTTCCTCTTCTGATACAGTAATGCCTATAGTCCCAATGTTTCACATATCAGCATGGGACT
TGCCATTTTCCTCCCTAATGACTGGAGCAAAATTAGTTTTACCCGGTCCTAGGCCTAAGGCAGAGGATATAGTGAAATTG
ATAAAAGAATTTAAGGTCACGGTGGGAGTAGGAGCACCTACTGTCTGGATTGATGTAGTAAATTATGTGGAAAGAGAGAA
TGTGGACCTACCACTAAAGGTCGTAGTGACTGGGGGTGCTGAGCCACCATTAGGATTGATCAAGAAACTGAAGGAACTGG
GAGTTAAGACTTATCACGCGTGGGGAATGACTGAAACTGAGGCAATAGCTACAGTAAACAAGAGCGATAATATAGAGAGA
ATGTCGGAACAAGGCTATCCAATTCCAGCATTTGAGATTGCATTAATGGGGCCAGAGGGAAACGAGTTACCTTGGGATGG
AAAATCGACAGGTGAGTTAGTGGCAAGAGGTGCATTCGTAACCAAAAAATATCTTAACGATAAATCCGATGCACAAACTA
AGTGGTTTAGGACTGGAGATGTGGCAAGGATAAACCCTGATGGAAGTGTGAAAGTTATAGACAGATTAAAGGATTTAATC
AAAAGTGGTGGGGAGTGGATAAGTAGTGTTGACCTAGAAAACGCCATTATGTCATATGAAAAAGTATTGGAGGCTGTTGT
GGTTGGAGTTAAGGATGAGAGGTGGGGGGAGAGACCAATTGCTCTTGTTGTAAAGAAGCCTGGAATGGACGTTAATGAAT
ATGAAATTATAGAGTATTTAAAGTCTTTAAATAGATTTCCAAAGTGGTGGTTGCCAGATAAGATAATATTCGTGGATTCC
ATACCTAAAACTAGTACTGGAAAACTAGATAAGAAACTAGTGAGGGAGCAGTTAAGATCAATGTTAGAAGAGAAGAAGTA
TTAA

Upstream 100 bases:

>100_bases
AGCTAACTAAGGATACGAGTAAGGTCTGCCACTTATTGCTAGTAGTATCATGAACTCAATAAATTAAAAGACTTATTAGA
ATAAAATGCGATAAATATTT

Downstream 100 bases:

>100_bases
ATGGACGCTTAATACTTATAAGTAGAGAAGGAGAACTAATACTATGCAATATACTATTCACGCTAAAACTCACAACAAAT
GGGATAATTCTTTACCTCCA

Product: medium-chain-fatty-acid--CoA ligase (alkK-3)

Products: NA

Alternate protein names: Medium-chain acyl-CoA synthetase [H]

Number of amino acids: Translated: 507; Mature: 507

Protein sequence:

>507_residues
MDSTIMDYNLNIRSIFWRIEKLYKDREIISRTYEGIVHYTYSDFALRVRKLATFLKTNGIAGEAVASIAWNTHRHLELYF
AVPLLGGVLHTVNVRFHESEMDYVIKSMGDKAIFMDKDINYKNSTLPTFIFDERYDEDVNSQESTSDFPDVDERQGAIAC
FTSGTTGKPKGVIYSHRSVFIHSLSLLAADALGISSSDTVMPIVPMFHISAWDLPFSSLMTGAKLVLPGPRPKAEDIVKL
IKEFKVTVGVGAPTVWIDVVNYVERENVDLPLKVVVTGGAEPPLGLIKKLKELGVKTYHAWGMTETEAIATVNKSDNIER
MSEQGYPIPAFEIALMGPEGNELPWDGKSTGELVARGAFVTKKYLNDKSDAQTKWFRTGDVARINPDGSVKVIDRLKDLI
KSGGEWISSVDLENAIMSYEKVLEAVVVGVKDERWGERPIALVVKKPGMDVNEYEIIEYLKSLNRFPKWWLPDKIIFVDS
IPKTSTGKLDKKLVREQLRSMLEEKKY

Sequences:

>Translated_507_residues
MDSTIMDYNLNIRSIFWRIEKLYKDREIISRTYEGIVHYTYSDFALRVRKLATFLKTNGIAGEAVASIAWNTHRHLELYF
AVPLLGGVLHTVNVRFHESEMDYVIKSMGDKAIFMDKDINYKNSTLPTFIFDERYDEDVNSQESTSDFPDVDERQGAIAC
FTSGTTGKPKGVIYSHRSVFIHSLSLLAADALGISSSDTVMPIVPMFHISAWDLPFSSLMTGAKLVLPGPRPKAEDIVKL
IKEFKVTVGVGAPTVWIDVVNYVERENVDLPLKVVVTGGAEPPLGLIKKLKELGVKTYHAWGMTETEAIATVNKSDNIER
MSEQGYPIPAFEIALMGPEGNELPWDGKSTGELVARGAFVTKKYLNDKSDAQTKWFRTGDVARINPDGSVKVIDRLKDLI
KSGGEWISSVDLENAIMSYEKVLEAVVVGVKDERWGERPIALVVKKPGMDVNEYEIIEYLKSLNRFPKWWLPDKIIFVDS
IPKTSTGKLDKKLVREQLRSMLEEKKY
>Mature_507_residues
MDSTIMDYNLNIRSIFWRIEKLYKDREIISRTYEGIVHYTYSDFALRVRKLATFLKTNGIAGEAVASIAWNTHRHLELYF
AVPLLGGVLHTVNVRFHESEMDYVIKSMGDKAIFMDKDINYKNSTLPTFIFDERYDEDVNSQESTSDFPDVDERQGAIAC
FTSGTTGKPKGVIYSHRSVFIHSLSLLAADALGISSSDTVMPIVPMFHISAWDLPFSSLMTGAKLVLPGPRPKAEDIVKL
IKEFKVTVGVGAPTVWIDVVNYVERENVDLPLKVVVTGGAEPPLGLIKKLKELGVKTYHAWGMTETEAIATVNKSDNIER
MSEQGYPIPAFEIALMGPEGNELPWDGKSTGELVARGAFVTKKYLNDKSDAQTKWFRTGDVARINPDGSVKVIDRLKDLI
KSGGEWISSVDLENAIMSYEKVLEAVVVGVKDERWGERPIALVVKKPGMDVNEYEIIEYLKSLNRFPKWWLPDKIIFVDS
IPKTSTGKLDKKLVREQLRSMLEEKKY

Specific function: Unknown

COG id: COG0318

COG function: function code IQ; Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]

Homologues:

Organism=Homo sapiens, GI156151445, Length=554, Percent_Identity=27.2563176895307, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI187761345, Length=512, Percent_Identity=22.65625, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI187761343, Length=512, Percent_Identity=22.65625, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI38505220, Length=355, Percent_Identity=28.7323943661972, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI42544132, Length=357, Percent_Identity=28.2913165266106, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI122937307, Length=355, Percent_Identity=28.4507042253521, Blast_Score=83, Evalue=7e-16,
Organism=Homo sapiens, GI57165412, Length=332, Percent_Identity=25.3012048192771, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI57165410, Length=332, Percent_Identity=25, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI58082049, Length=381, Percent_Identity=24.6719160104987, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI157311624, Length=386, Percent_Identity=24.0932642487047, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI157311622, Length=386, Percent_Identity=24.0932642487047, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI28416953, Length=374, Percent_Identity=23.2620320855615, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI145693145, Length=357, Percent_Identity=29.9719887955182, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1786810, Length=354, Percent_Identity=28.2485875706215, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1788107, Length=371, Percent_Identity=26.6846361185984, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI221142682, Length=500, Percent_Identity=21.4, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1788595, Length=473, Percent_Identity=22.8329809725159, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1789201, Length=357, Percent_Identity=25.2100840336134, Blast_Score=78, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71994694, Length=536, Percent_Identity=26.3059701492537, Blast_Score=139, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI71994703, Length=536, Percent_Identity=26.3059701492537, Blast_Score=139, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI71994690, Length=536, Percent_Identity=26.3059701492537, Blast_Score=139, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI17560308, Length=459, Percent_Identity=27.0152505446623, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17557194, Length=497, Percent_Identity=26.9617706237425, Blast_Score=129, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17538037, Length=501, Percent_Identity=26.9461077844311, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17558820, Length=483, Percent_Identity=26.2939958592132, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71996755, Length=490, Percent_Identity=25.7142857142857, Blast_Score=118, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI17531443, Length=508, Percent_Identity=25.7874015748031, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17559526, Length=361, Percent_Identity=25.4847645429363, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI32563687, Length=480, Percent_Identity=23.75, Blast_Score=106, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17560140, Length=346, Percent_Identity=23.4104046242775, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17507435, Length=392, Percent_Identity=23.469387755102, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71985884, Length=372, Percent_Identity=24.1935483870968, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17556552, Length=364, Percent_Identity=25.5494505494505, Blast_Score=80, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6319699, Length=471, Percent_Identity=26.3269639065817, Blast_Score=120, Evalue=5e-28,
Organism=Saccharomyces cerevisiae, GI6319264, Length=417, Percent_Identity=23.021582733813, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24581924, Length=395, Percent_Identity=30.126582278481, Blast_Score=141, Evalue=9e-34,
Organism=Drosophila melanogaster, GI21355181, Length=512, Percent_Identity=25.78125, Blast_Score=141, Evalue=1e-33,
Organism=Drosophila melanogaster, GI18859661, Length=361, Percent_Identity=29.6398891966759, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI20130357, Length=525, Percent_Identity=24.7619047619048, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24653035, Length=475, Percent_Identity=25.4736842105263, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI161076582, Length=488, Percent_Identity=24.7950819672131, Blast_Score=103, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24648253, Length=493, Percent_Identity=21.7038539553753, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24648255, Length=492, Percent_Identity=21.9512195121951, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24648260, Length=479, Percent_Identity=23.7995824634656, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI21356947, Length=477, Percent_Identity=23.0607966457023, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21356441, Length=484, Percent_Identity=23.7603305785124, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI281365686, Length=486, Percent_Identity=21.1934156378601, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24656500, Length=520, Percent_Identity=24.0384615384615, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI21358303, Length=499, Percent_Identity=21.8436873747495, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020845
- InterPro:   IPR000873 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: NA

Molecular weight: Translated: 57130; Mature: 57130

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSTIMDYNLNIRSIFWRIEKLYKDREIISRTYEGIVHYTYSDFALRVRKLATFLKTNGI
CCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEEHHHHHHHHHHHHHHHHCCCC
AGEAVASIAWNTHRHLELYFAVPLLGGVLHTVNVRFHESEMDYVIKSMGDKAIFMDKDIN
CHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHEEEEEECHHHHHHHHHCCCCEEEEECCCC
YKNSTLPTFIFDERYDEDVNSQESTSDFPDVDERQGAIACFTSGTTGKPKGVIYSHRSVF
CCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEECHHHH
IHSLSLLAADALGISSSDTVMPIVPMFHISAWDLPFSSLMTGAKLVLPGPRPKAEDIVKL
HHHHHHHHHHHCCCCCCCCEEEEEHEEECEECCCCHHHHHCCCEEEECCCCCCHHHHHHH
IKEFKVTVGVGAPTVWIDVVNYVERENVDLPLKVVVTGGAEPPLGLIKKLKELGVKTYHA
HHHHEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEE
WGMTETEAIATVNKSDNIERMSEQGYPIPAFEIALMGPEGNELPWDGKSTGELVARGAFV
CCCCCCHHEEEECCCCCHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHH
TKKYLNDKSDAQTKWFRTGDVARINPDGSVKVIDRLKDLIKSGGEWISSVDLENAIMSYE
HHHHHCCCCCCCHHEEECCCEEEECCCCCCHHHHHHHHHHHCCCHHHHHCCHHHHHHHHH
KVLEAVVVGVKDERWGERPIALVVKKPGMDVNEYEIIEYLKSLNRFPKWWLPDKIIFVDS
HHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEC
IPKTSTGKLDKKLVREQLRSMLEEKKY
CCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDSTIMDYNLNIRSIFWRIEKLYKDREIISRTYEGIVHYTYSDFALRVRKLATFLKTNGI
CCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEEHHHHHHHHHHHHHHHHCCCC
AGEAVASIAWNTHRHLELYFAVPLLGGVLHTVNVRFHESEMDYVIKSMGDKAIFMDKDIN
CHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHEEEEEECHHHHHHHHHCCCCEEEEECCCC
YKNSTLPTFIFDERYDEDVNSQESTSDFPDVDERQGAIACFTSGTTGKPKGVIYSHRSVF
CCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEECHHHH
IHSLSLLAADALGISSSDTVMPIVPMFHISAWDLPFSSLMTGAKLVLPGPRPKAEDIVKL
HHHHHHHHHHHCCCCCCCCEEEEEHEEECEECCCCHHHHHCCCEEEECCCCCCHHHHHHH
IKEFKVTVGVGAPTVWIDVVNYVERENVDLPLKVVVTGGAEPPLGLIKKLKELGVKTYHA
HHHHEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEE
WGMTETEAIATVNKSDNIERMSEQGYPIPAFEIALMGPEGNELPWDGKSTGELVARGAFV
CCCCCCHHEEEECCCCCHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHH
TKKYLNDKSDAQTKWFRTGDVARINPDGSVKVIDRLKDLIKSGGEWISSVDLENAIMSYE
HHHHHCCCCCCCHHEEECCCEEEECCCCCCHHHHHHHHHHHCCCHHHHHCCHHHHHHHHH
KVLEAVVVGVKDERWGERPIALVVKKPGMDVNEYEIIEYLKSLNRFPKWWLPDKIIFVDS
HHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEC
IPKTSTGKLDKKLVREQLRSMLEEKKY
CCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1453953 [H]