Click here to switch to the map view.

The map label for this gene is yeaE [H]

Identifier: 15899494

GI number: 15899494

Start: 2535490

End: 2536368

Strand: Reverse

Name: yeaE [H]

Synonym: SSO2779

Alternate gene names: 15899494

Gene position: 2536368-2535490 (Counterclockwise)

Preceding gene: 15899495

Following gene: 15899493

Centisome position: 84.76

GC content: 38.79

Gene sequence:

>879_bases
ATGGAAGACGTTAAGAAATTTAAATACTTTACAGTATCACCTCTAGCTTTTGGAACCTGGAGGATTGGGGGAGGTTATTG
GTACTCCTCTCATGACAGAGACAATGAATGGGTAGGTGCGATTCGTAGGGCAATAGAACTAGGACTAAGAGTTATCGACA
CTGCTGAAATGTACGGTAATGGTCACGCTGAGGAATTGGTAGGTGAAGCGATCAAGGAATTTAGCAGAGAAGAATTGTTT
ATAGTGTCTAAGGTTTGGCCTAGTCATGCTGACTATGATAATGTAATAAAGTCAGCTAAAAATAGTTCAAGAAGACTAGG
CACATACATAGATCTTTATTTACTTCACGCTCCATCAAGAGTACCGATTTGCAAGACTATAAGGGCATTTGAGAAACTGG
TAGATGATGGTGTAATAAGGTTTTTTGGGCTCAGTAACTTCGATGTGGACCAAATAGAGAGCGCCAGAGAGTGTGTCAGT
AAGTATGAAATTGTCGCAATTCAAAATCACTATAGTTTGCTAAGTAGAAGTGATGAGAGGAGGGCTTTAGCTTACGCGGA
GAAAAATGGACTGATGTATATGGCGTATACACCATTGGAAAATGGAATATTAGCTAGGAATGAGTTCTTAGCTAATATAG
GTAAGAAGTACAATAAGACTGCAACTCAAGTAGCCTTAAATTGGTATATTACTGGTAAAAACAGTTTGATACCAATAGTG
AAAGCCTCTAAAATACCCCATATAGAGGAAAATGCTGGTGCAATGGGTTGGAGATTGTCAGAAGAGGATTGGAGGGCAAT
AGATGAGCATTTTAGAGAGAAGAGTTATTTTCTAGATAAGTTTGTATCGTCTTTGAAATCGATGAGACCTTGGTCTTAG

Upstream 100 bases:

>100_bases
GTATATTAGGAAGAGAGTTTGTCCTTTAAAGTCTCAGAAAGTATAGACAAGATATGCATTAGAAGACAATTTTTAAAAGG
AACGAATTTAAGGTATATTT

Downstream 100 bases:

>100_bases
TTAATTTTAAAATTATATAATCAAATAAGTATCTATGAAGAGAATCTTAGTAGGTTATGATGGTTCGGAAAACGCAGAAA
GGGCTTTAGATTTTGCGATA

Product: dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MEDVKKFKYFTVSPLAFGTWRIGGGYWYSSHDRDNEWVGAIRRAIELGLRVIDTAEMYGNGHAEELVGEAIKEFSREELF
IVSKVWPSHADYDNVIKSAKNSSRRLGTYIDLYLLHAPSRVPICKTIRAFEKLVDDGVIRFFGLSNFDVDQIESARECVS
KYEIVAIQNHYSLLSRSDERRALAYAEKNGLMYMAYTPLENGILARNEFLANIGKKYNKTATQVALNWYITGKNSLIPIV
KASKIPHIEENAGAMGWRLSEEDWRAIDEHFREKSYFLDKFVSSLKSMRPWS

Sequences:

>Translated_292_residues
MEDVKKFKYFTVSPLAFGTWRIGGGYWYSSHDRDNEWVGAIRRAIELGLRVIDTAEMYGNGHAEELVGEAIKEFSREELF
IVSKVWPSHADYDNVIKSAKNSSRRLGTYIDLYLLHAPSRVPICKTIRAFEKLVDDGVIRFFGLSNFDVDQIESARECVS
KYEIVAIQNHYSLLSRSDERRALAYAEKNGLMYMAYTPLENGILARNEFLANIGKKYNKTATQVALNWYITGKNSLIPIV
KASKIPHIEENAGAMGWRLSEEDWRAIDEHFREKSYFLDKFVSSLKSMRPWS
>Mature_292_residues
MEDVKKFKYFTVSPLAFGTWRIGGGYWYSSHDRDNEWVGAIRRAIELGLRVIDTAEMYGNGHAEELVGEAIKEFSREELF
IVSKVWPSHADYDNVIKSAKNSSRRLGTYIDLYLLHAPSRVPICKTIRAFEKLVDDGVIRFFGLSNFDVDQIESARECVS
KYEIVAIQNHYSLLSRSDERRALAYAEKNGLMYMAYTPLENGILARNEFLANIGKKYNKTATQVALNWYITGKNSLIPIV
KASKIPHIEENAGAMGWRLSEEDWRAIDEHFREKSYFLDKFVSSLKSMRPWS

Specific function: Unknown

COG id: COG0656

COG function: function code R; Aldo/keto reductases, related to diketogulonate reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI223468663, Length=284, Percent_Identity=29.5774647887324, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI291291012, Length=288, Percent_Identity=29.8611111111111, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI24497577, Length=286, Percent_Identity=27.2727272727273, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI5174391, Length=286, Percent_Identity=27.2727272727273, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI24497583, Length=303, Percent_Identity=26.4026402640264, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI310109922, Length=280, Percent_Identity=26.4285714285714, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI5174695, Length=267, Percent_Identity=26.5917602996255, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI5453543, Length=300, Percent_Identity=26, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI310109920, Length=300, Percent_Identity=25.6666666666667, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI45446745, Length=300, Percent_Identity=25.3333333333333, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI4503285, Length=300, Percent_Identity=25.3333333333333, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI4502049, Length=287, Percent_Identity=29.616724738676, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI24497585, Length=300, Percent_Identity=25, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI300116273, Length=250, Percent_Identity=26.8, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI27436962, Length=211, Percent_Identity=28.9099526066351, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI27436964, Length=209, Percent_Identity=29.1866028708134, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI27436966, Length=211, Percent_Identity=28.9099526066351, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1788081, Length=259, Percent_Identity=37.4517374517375, Blast_Score=151, Evalue=5e-38,
Organism=Escherichia coli, GI1786400, Length=264, Percent_Identity=31.8181818181818, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1788070, Length=308, Percent_Identity=29.8701298701299, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI87081735, Length=273, Percent_Identity=26.3736263736264, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1787674, Length=281, Percent_Identity=26.3345195729537, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI87082198, Length=252, Percent_Identity=29.7619047619048, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1789375, Length=284, Percent_Identity=24.2957746478873, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI48994888, Length=294, Percent_Identity=25.1700680272109, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789199, Length=273, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI71998625, Length=277, Percent_Identity=28.8808664259928, Blast_Score=103, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17564128, Length=310, Percent_Identity=26.7741935483871, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17537075, Length=303, Percent_Identity=28.0528052805281, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17537077, Length=321, Percent_Identity=28.3489096573209, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17550248, Length=301, Percent_Identity=26.578073089701, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17538386, Length=293, Percent_Identity=26.6211604095563, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17566692, Length=314, Percent_Identity=27.0700636942675, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17561300, Length=282, Percent_Identity=25.531914893617, Blast_Score=77, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6325169, Length=229, Percent_Identity=25.764192139738, Blast_Score=87, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6322556, Length=277, Percent_Identity=27.0758122743682, Blast_Score=86, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6320576, Length=255, Percent_Identity=26.6666666666667, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6320079, Length=270, Percent_Identity=25.1851851851852, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI20129731, Length=287, Percent_Identity=29.9651567944251, Blast_Score=108, Evalue=6e-24,
Organism=Drosophila melanogaster, GI24663317, Length=292, Percent_Identity=30.4794520547945, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24657054, Length=267, Percent_Identity=29.2134831460674, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24662789, Length=289, Percent_Identity=29.0657439446367, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI45553081, Length=261, Percent_Identity=27.2030651340996, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI21356425, Length=295, Percent_Identity=26.1016949152542, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI281366140, Length=253, Percent_Identity=26.8774703557312, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24646159, Length=206, Percent_Identity=30.0970873786408, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24646155, Length=154, Percent_Identity=29.2207792207792, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 33604; Mature: 33604

Theoretical pI: Translated: 8.18; Mature: 8.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDVKKFKYFTVSPLAFGTWRIGGGYWYSSHDRDNEWVGAIRRAIELGLRVIDTAEMYGN
CCCHHHCCEEEECCCEEEEEEECCEEEECCCCCCHHHHHHHHHHHHHHHHHEEHHHHHCC
GHAEELVGEAIKEFSREELFIVSKVWPSHADYDNVIKSAKNSSRRLGTYIDLYLLHAPSR
CCHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHCCCCHHHHHHEEEEEEECCCC
VPICKTIRAFEKLVDDGVIRFFGLSNFDVDQIESARECVSKYEIVAIQNHYSLLSRSDER
CCHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHEEEEEECHHHHHHCCCCH
RALAYAEKNGLMYMAYTPLENGILARNEFLANIGKKYNKTATQVALNWYITGKNSLIPIV
HHHHEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCHHHEEEEEEEEECCCCEEEEE
KASKIPHIEENAGAMGWRLSEEDWRAIDEHFREKSYFLDKFVSSLKSMRPWS
ECCCCCCCCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MEDVKKFKYFTVSPLAFGTWRIGGGYWYSSHDRDNEWVGAIRRAIELGLRVIDTAEMYGN
CCCHHHCCEEEECCCEEEEEEECCEEEECCCCCCHHHHHHHHHHHHHHHHHEEHHHHHCC
GHAEELVGEAIKEFSREELFIVSKVWPSHADYDNVIKSAKNSSRRLGTYIDLYLLHAPSR
CCHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHCCCCHHHHHHEEEEEEECCCC
VPICKTIRAFEKLVDDGVIRFFGLSNFDVDQIESARECVSKYEIVAIQNHYSLLSRSDER
CCHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHEEEEEECHHHHHHCCCCH
RALAYAEKNGLMYMAYTPLENGILARNEFLANIGKKYNKTATQVALNWYITGKNSLIPIV
HHHHEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCHHHEEEEEEEEECCCCEEEEE
KASKIPHIEENAGAMGWRLSEEDWRAIDEHFREKSYFLDKFVSSLKSMRPWS
ECCCCCCCCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]