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The map label for this gene is hpcE-2 [C]

Identifier: 15899487

GI number: 15899487

Start: 2529509

End: 2530423

Strand: Reverse

Name: hpcE-2 [C]

Synonym: SSO2773

Alternate gene names: 15899487

Gene position: 2530423-2529509 (Counterclockwise)

Preceding gene: 15899488

Following gene: 15899483

Centisome position: 84.57

GC content: 37.6

Gene sequence:

>915_bases
ATGGTTAAAATCCTATTATTCTCTCCAAATCCTAACGAATTTAAGAGAGTTGGTGTTTATGAGAACGGTAGGGTCATTGA
CCTAGTAAAGGCTTATGAACTATTATATGACGCTAAGCCCCCAAATTGGTTTTACGATACTAAGGATTTAATTGAAGGTG
GAAATGGCTCAATCTTACTGATAAAGAGTGTTTTGGATAGTTTAAGGGGTAAGGAGGACAAAGTGTCTTATGATCCAGAG
AAGATTTTCTATTATCCACCTATTACTAATCCAGAGAAGATTTTCCTCTTGGCTGTTAATTACAAGGCTCACGGCAAGGA
GACTAATAATGAACCTCCAAAGGAACCTTACATTTTTACTAAGTTCTCAAACGCGTTAATCGGTCATAATCAACCTATAC
TGTATCCGAAAGCATCAAATAAGGTTGATTACGAAATTGAGCTAGGAGTTATAATTGGGAAACAAGGGAAGTATGTAAAG
AGAGAAAGAGCGTTTGATTACGTATTTGGTTATACAGTGTTCAACGATATTAGTTATAGGGATAGACAATTTCCATCAGA
AATGCCCTATGGTATGAGGTGGGTTCACGGTAAGGGTATGGACACTGGAGCACCAATGGGACCGTGGATAGTTACCAAGG
ATGAAATTCCAAACCCTTATGAATTGAGGTTGACTTTAAGAGTTAACGGGGAAGTTAGGCAAGACGCTTACGCTGAGGAC
ATGATATTTAAGATTGATGAGATAATCGAGTATTTGTCAAATGGTATAACATTAAAACCTGGAGATATAATATCTACTGG
AACTCCGCCTGGAGTTGGATTAGCTACTGGAAAATTCTTGAAACCGGGCGATACAATTGAGGCGGAGATAAGCAAGATAG
GAGTGTTAAGGAATTATTTAGTAAAAGAAGAATAA

Upstream 100 bases:

>100_bases
AGTCCAACAGTTCTAAGAGTTCACGTTAGCCCTAATAGTATACCTTCTAGATTGTTAATGAAAAGATAGTTATTTATATT
AAAAATAAGGAGTTTTACCT

Downstream 100 bases:

>100_bases
AATTATTAAATCTTTATTATAACGTAATTTATTCCCAAATAGGCTAGGAAGAATAATGGTAGTATAAGATCTGGTATGTC
AAAGACAACTTCACTTATCC

Product: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (hpcE-2)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MVKILLFSPNPNEFKRVGVYENGRVIDLVKAYELLYDAKPPNWFYDTKDLIEGGNGSILLIKSVLDSLRGKEDKVSYDPE
KIFYYPPITNPEKIFLLAVNYKAHGKETNNEPPKEPYIFTKFSNALIGHNQPILYPKASNKVDYEIELGVIIGKQGKYVK
RERAFDYVFGYTVFNDISYRDRQFPSEMPYGMRWVHGKGMDTGAPMGPWIVTKDEIPNPYELRLTLRVNGEVRQDAYAED
MIFKIDEIIEYLSNGITLKPGDIISTGTPPGVGLATGKFLKPGDTIEAEISKIGVLRNYLVKEE

Sequences:

>Translated_304_residues
MVKILLFSPNPNEFKRVGVYENGRVIDLVKAYELLYDAKPPNWFYDTKDLIEGGNGSILLIKSVLDSLRGKEDKVSYDPE
KIFYYPPITNPEKIFLLAVNYKAHGKETNNEPPKEPYIFTKFSNALIGHNQPILYPKASNKVDYEIELGVIIGKQGKYVK
RERAFDYVFGYTVFNDISYRDRQFPSEMPYGMRWVHGKGMDTGAPMGPWIVTKDEIPNPYELRLTLRVNGEVRQDAYAED
MIFKIDEIIEYLSNGITLKPGDIISTGTPPGVGLATGKFLKPGDTIEAEISKIGVLRNYLVKEE
>Mature_304_residues
MVKILLFSPNPNEFKRVGVYENGRVIDLVKAYELLYDAKPPNWFYDTKDLIEGGNGSILLIKSVLDSLRGKEDKVSYDPE
KIFYYPPITNPEKIFLLAVNYKAHGKETNNEPPKEPYIFTKFSNALIGHNQPILYPKASNKVDYEIELGVIIGKQGKYVK
RERAFDYVFGYTVFNDISYRDRQFPSEMPYGMRWVHGKGMDTGAPMGPWIVTKDEIPNPYELRLTLRVNGEVRQDAYAED
MIFKIDEIIEYLSNGITLKPGDIISTGTPPGVGLATGKFLKPGDTIEAEISKIGVLRNYLVKEE

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=224, Percent_Identity=41.9642857142857, Blast_Score=197, Evalue=8e-51,
Organism=Homo sapiens, GI40786394, Length=224, Percent_Identity=41.5178571428571, Blast_Score=193, Evalue=2e-49,
Organism=Homo sapiens, GI66348062, Length=197, Percent_Identity=40.1015228426396, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI13654274, Length=197, Percent_Identity=40.1015228426396, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI215422413, Length=197, Percent_Identity=40.1015228426396, Blast_Score=133, Evalue=2e-31,
Organism=Escherichia coli, GI1787428, Length=182, Percent_Identity=36.2637362637363, Blast_Score=117, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17557057, Length=195, Percent_Identity=36.4102564102564, Blast_Score=130, Evalue=9e-31,
Organism=Saccharomyces cerevisiae, GI6324161, Length=233, Percent_Identity=32.1888412017167, Blast_Score=106, Evalue=4e-24,
Organism=Drosophila melanogaster, GI28572127, Length=224, Percent_Identity=44.1964285714286, Blast_Score=192, Evalue=2e-49,
Organism=Drosophila melanogaster, GI24663695, Length=243, Percent_Identity=37.4485596707819, Blast_Score=149, Evalue=2e-36,
Organism=Drosophila melanogaster, GI28571789, Length=209, Percent_Identity=36.8421052631579, Blast_Score=134, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 34593; Mature: 34593

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKILLFSPNPNEFKRVGVYENGRVIDLVKAYELLYDAKPPNWFYDTKDLIEGGNGSILL
CEEEEEECCCCCHHEEECCCCCCCEEHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCEEE
IKSVLDSLRGKEDKVSYDPEKIFYYPPITNPEKIFLLAVNYKAHGKETNNEPPKEPYIFT
HHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCEEEEEEEECEECCCCCCCCCCCCCEEEE
KFSNALIGHNQPILYPKASNKVDYEIELGVIIGKQGKYVKRERAFDYVFGYTVFNDISYR
EECCCEECCCCCEEEECCCCCEEEEEEEEEEECCCCCCHHHHHHHEEEEEEEEECCCCCH
DRQFPSEMPYGMRWVHGKGMDTGAPMGPWIVTKDEIPNPYELRLTLRVNGEVRQDAYAED
HHCCCCCCCCCEEEEECCCCCCCCCCCCEEEECCCCCCCEEEEEEEEECCCCCCHHHHHH
MIFKIDEIIEYLSNGITLKPGDIISTGTPPGVGLATGKFLKPGDTIEAEISKIGVLRNYL
HHHHHHHHHHHHHCCCEECCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
VKEE
HCCC
>Mature Secondary Structure
MVKILLFSPNPNEFKRVGVYENGRVIDLVKAYELLYDAKPPNWFYDTKDLIEGGNGSILL
CEEEEEECCCCCHHEEECCCCCCCEEHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCEEE
IKSVLDSLRGKEDKVSYDPEKIFYYPPITNPEKIFLLAVNYKAHGKETNNEPPKEPYIFT
HHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCEEEEEEEECEECCCCCCCCCCCCCEEEE
KFSNALIGHNQPILYPKASNKVDYEIELGVIIGKQGKYVKRERAFDYVFGYTVFNDISYR
EECCCEECCCCCEEEECCCCCEEEEEEEEEEECCCCCCHHHHHHHEEEEEEEEECCCCCH
DRQFPSEMPYGMRWVHGKGMDTGAPMGPWIVTKDEIPNPYELRLTLRVNGEVRQDAYAED
HHCCCCCCCCCEEEEECCCCCCCCCCCCEEEECCCCCCCEEEEEEEEECCCCCCHHHHHH
MIFKIDEIIEYLSNGITLKPGDIISTGTPPGVGLATGKFLKPGDTIEAEISKIGVLRNYL
HHHHHHHHHHHHHCCCEECCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
VKEE
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]