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The map label for this gene is dmsB [H]

Identifier: 15899475

GI number: 15899475

Start: 2514624

End: 2515853

Strand: Reverse

Name: dmsB [H]

Synonym: SSO2759

Alternate gene names: 15899475

Gene position: 2515853-2514624 (Counterclockwise)

Preceding gene: 15899476

Following gene: 15899474

Centisome position: 84.08

GC content: 34.55

Gene sequence:

>1230_bases
ATGTTATTAACCTATCTTACGAGATATTATCATATGGAAAGGAAACTGGGATTTATATTTGATCACAATAAGTGCATAAT
TTGTAACGCTTGTGTAGATGCTTGTAATAAAGCTTACGGGGACCTTAACTGGAGAAGTCTAATAGTAATGACCCATGGTG
AGAGTAAAACAGCACTTTCTATTGCTTGCAATCATTGCGATAATCCGACATGTATGCAAGTATGCCCCGCCAATGCGATT
GAGAAGAACGAAATGGGGATAGTCAGAATAAGGGATGATAAATGTATAGGGTGTGGATTTTGTACATGGGCGTGCCCATA
TGAAGCGTTAAAATTCAATAATGAGGGAGTCATGAGCAAATGTCACTTTTGTTATGACCGTTTAGCGGAGGGAAAGGGAA
TACCATACTGTGTTGAGGCATGTCCTACTGGTGCGTTAGCATTCGGTTGGATAGAAAAAGGAGAAGCAGAAGTAAATTAT
CTTCCACCCTCGGAAATAACTAAACCTAGAATTGTTATAAAACAACCAGAATCAAAGGAAACTCTCAATGCAAGTGTGTT
GCATACTAAGAAAGAGGAGAATTATTTAGGACTATTAGCCTTTACGATTGGAAGTGAATTCGCGTTAGGTTATTCCCTTT
TTAAATTACCTCTCTGGAGTATTGTGAGTGTTATCTTACTAGTAGCCTCATTGCTTTTATCTGTAAATCACGCTAGGAAA
ACTGATAGGTTTTATAGAGTTATTTATAACTTGAAAACCTCTTGGTTAAGCAGAGAGGTATTATTTTCATCGATAGCAAT
ATTATTCTATATTTTGAGTATTGCCGAACCTCTATTTTATTACCCTGCCATATTATTTCTGACTGTTGGAGTAATTTCCA
GTATTATGATCTATATGTTGAAAAGTAGACCATCATGGTATAATGTTGATACTCCAGTTTCGTTCATAGGGAGTATCTTT
ACGATGTCTCTCCCAATTGTGTACTTTTTCAGTCACAATTTAACAACTATTATTCCATTAATAATAACTCTTGTAATAGA
AATAATTTCTAATAATAGAAGGTCAAACGTTAGAATGAGCCTTAATGTCGCTTCAATAGTTATATCACTAATTTCTATTG
TTTTCCCCGAAATTATCATCATAACTGAAATTATAAATATTGTTTCTGAAGTAACGCATAGGAGAGAGTTTTATGAAAAA
GTTGTATATTACGGCTTACCTAAAGTTTAA

Upstream 100 bases:

>100_bases
GTTCGTGTTCAATTGCCTCTCTTATGAAATTCCTCATTAGTGCGTATTTGTAAAATGGTGTTTCCATAAAATTTGATCAA
TTTATATCGATATAAAGCTA

Downstream 100 bases:

>100_bases
ACATTTTTTATAGTAAGTTTTTTAAATGATGAAGAGTATACAGTTCTAATAGGTGGTCATTTATTGCTCGAAATAAGATT
CCACGGTAGGGGTGGACAAG

Product: molybdopterin oxidoreductase, iron-sulfur binding subunit

Products: Reduced form of N-Oxide compounds [C]

Alternate protein names: DMSO reductase iron-sulfur subunit [H]

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MLLTYLTRYYHMERKLGFIFDHNKCIICNACVDACNKAYGDLNWRSLIVMTHGESKTALSIACNHCDNPTCMQVCPANAI
EKNEMGIVRIRDDKCIGCGFCTWACPYEALKFNNEGVMSKCHFCYDRLAEGKGIPYCVEACPTGALAFGWIEKGEAEVNY
LPPSEITKPRIVIKQPESKETLNASVLHTKKEENYLGLLAFTIGSEFALGYSLFKLPLWSIVSVILLVASLLLSVNHARK
TDRFYRVIYNLKTSWLSREVLFSSIAILFYILSIAEPLFYYPAILFLTVGVISSIMIYMLKSRPSWYNVDTPVSFIGSIF
TMSLPIVYFFSHNLTTIIPLIITLVIEIISNNRRSNVRMSLNVASIVISLISIVFPEIIIITEIINIVSEVTHRREFYEK
VVYYGLPKV

Sequences:

>Translated_409_residues
MLLTYLTRYYHMERKLGFIFDHNKCIICNACVDACNKAYGDLNWRSLIVMTHGESKTALSIACNHCDNPTCMQVCPANAI
EKNEMGIVRIRDDKCIGCGFCTWACPYEALKFNNEGVMSKCHFCYDRLAEGKGIPYCVEACPTGALAFGWIEKGEAEVNY
LPPSEITKPRIVIKQPESKETLNASVLHTKKEENYLGLLAFTIGSEFALGYSLFKLPLWSIVSVILLVASLLLSVNHARK
TDRFYRVIYNLKTSWLSREVLFSSIAILFYILSIAEPLFYYPAILFLTVGVISSIMIYMLKSRPSWYNVDTPVSFIGSIF
TMSLPIVYFFSHNLTTIIPLIITLVIEIISNNRRSNVRMSLNVASIVISLISIVFPEIIIITEIINIVSEVTHRREFYEK
VVYYGLPKV
>Mature_409_residues
MLLTYLTRYYHMERKLGFIFDHNKCIICNACVDACNKAYGDLNWRSLIVMTHGESKTALSIACNHCDNPTCMQVCPANAI
EKNEMGIVRIRDDKCIGCGFCTWACPYEALKFNNEGVMSKCHFCYDRLAEGKGIPYCVEACPTGALAFGWIEKGEAEVNY
LPPSEITKPRIVIKQPESKETLNASVLHTKKEENYLGLLAFTIGSEFALGYSLFKLPLWSIVSVILLVASLLLSVNHARK
TDRFYRVIYNLKTSWLSREVLFSSIAILFYILSIAEPLFYYPAILFLTVGVISSIMIYMLKSRPSWYNVDTPVSFIGSIF
TMSLPIVYFFSHNLTTIIPLIITLVIEIISNNRRSNVRMSLNVASIVISLISIVFPEIIIITEIINIVSEVTHRREFYEK
VVYYGLPKV

Specific function: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds [H]

COG id: COG0437

COG function: function code C; Fe-S-cluster-containing hydrogenase components 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Escherichia coli, GI1787122, Length=186, Percent_Identity=42.4731182795699, Blast_Score=129, Evalue=5e-31,
Organism=Escherichia coli, GI1787872, Length=186, Percent_Identity=42.4731182795699, Blast_Score=128, Evalue=8e-31,
Organism=Escherichia coli, GI226510944, Length=156, Percent_Identity=37.1794871794872, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI2367345, Length=158, Percent_Identity=32.9113924050633, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1789370, Length=202, Percent_Identity=33.6633663366337, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI1787749, Length=167, Percent_Identity=33.5329341317365, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1790326, Length=175, Percent_Identity=32, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI87082180, Length=130, Percent_Identity=35.3846153846154, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1787740, Length=107, Percent_Identity=37.3831775700935, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787478, Length=81, Percent_Identity=44.4444444444444, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788811, Length=142, Percent_Identity=28.8732394366197, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI2367245, Length=150, Percent_Identity=32.6666666666667, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1789067, Length=153, Percent_Identity=31.3725490196078, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI87082179, Length=141, Percent_Identity=31.2056737588652, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR014297 [H]

Pfam domain/function: PF00037 Fer4 [H]

EC number: NA

Molecular weight: Translated: 46418; Mature: 46418

Theoretical pI: Translated: 8.00; Mature: 8.00

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLTYLTRYYHMERKLGFIFDHNKCIICNACVDACNKAYGDLNWRSLIVMTHGESKTALS
CHHHHHHHHHHHHHHCCEEEECCCEEEEHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEE
IACNHCDNPTCMQVCPANAIEKNEMGIVRIRDDKCIGCGFCTWACPYEALKFNNEGVMSK
EEECCCCCCCHHHCCCCCCCCCCCCCEEEECCCCEEECCCHHHHCCHHHHEECCCCHHHH
CHFCYDRLAEGKGIPYCVEACPTGALAFGWIEKGEAEVNYLPPSEITKPRIVIKQPESKE
HHHHHHHHHCCCCCCHHHHCCCCCCEEECCCCCCCCEEECCCCCCCCCCEEEEECCCCCH
TLNASVLHTKKEENYLGLLAFTIGSEFALGYSLFKLPLWSIVSVILLVASLLLSVNHARK
HCCHHHEECCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TDRFYRVIYNLKTSWLSREVLFSSIAILFYILSIAEPLFYYPAILFLTVGVISSIMIYML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KSRPSWYNVDTPVSFIGSIFTMSLPIVYFFSHNLTTIIPLIITLVIEIISNNRRSNVRMS
HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEE
LNVASIVISLISIVFPEIIIITEIINIVSEVTHRREFYEKVVYYGLPKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLLTYLTRYYHMERKLGFIFDHNKCIICNACVDACNKAYGDLNWRSLIVMTHGESKTALS
CHHHHHHHHHHHHHHCCEEEECCCEEEEHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEE
IACNHCDNPTCMQVCPANAIEKNEMGIVRIRDDKCIGCGFCTWACPYEALKFNNEGVMSK
EEECCCCCCCHHHCCCCCCCCCCCCCEEEECCCCEEECCCHHHHCCHHHHEECCCCHHHH
CHFCYDRLAEGKGIPYCVEACPTGALAFGWIEKGEAEVNYLPPSEITKPRIVIKQPESKE
HHHHHHHHHCCCCCCHHHHCCCCCCEEECCCCCCCCEEECCCCCCCCCCEEEEECCCCCH
TLNASVLHTKKEENYLGLLAFTIGSEFALGYSLFKLPLWSIVSVILLVASLLLSVNHARK
HCCHHHEECCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TDRFYRVIYNLKTSWLSREVLFSSIAILFYILSIAEPLFYYPAILFLTVGVISSIMIYML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KSRPSWYNVDTPVSFIGSIFTMSLPIVYFFSHNLTTIIPLIITLVIEIISNNRRSNVRMS
HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEE
LNVASIVISLISIVFPEIIIITEIINIVSEVTHRREFYEKVVYYGLPKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Iron-Sulfur Cluster. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-Oxide; Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

Specific reaction: Reduces Various N-Oxide And Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3062312; 8905232; 9278503; 2174699; 1653010 [H]