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The map label for this gene is gabT-1 [H]

Identifier: 15899443

GI number: 15899443

Start: 2481492

End: 2482814

Strand: Direct

Name: gabT-1 [H]

Synonym: SSO2727

Alternate gene names: 15899443

Gene position: 2481492-2482814 (Clockwise)

Preceding gene: 15899440

Following gene: 15899444

Centisome position: 82.93

GC content: 38.17

Gene sequence:

>1323_bases
ATGGAAGAAAATTTAGACAGTAGTGTATTGGAAGCTCCAATAATTAACGTAACTCCACCAGGTTCTAAATCACTTAAGTT
GTTAAAAGACCAAGAAGAGTATGAAACTTCAGCTATAAACTACCCTAAGTACTTTAAGATAGCAATAGATAAGGCTCAAG
GTTCAACAGTAACTGATGTTGATGGTAATGTGTATATAGATCTGGTTACCGGTATATCTGTTGTCAATCTAGGTCATAAT
AATCCCTTTGTGAGGAAGAGAGTTCAAGAACAGTTAGAAAAGGTTTGGCACACATTAGAGGTACCTACGGAAATTAGGGT
TAACTTTAGTAAAAAATTATTATCAACTCTAGGAATGAGAGCTAAATTATTATTTACTACAACTGGGGCAGATGCGGTGG
AAGCTGCAGTAAAGATAGCTAGATTCATAACTGGAAAGAAGACTATAATTGCATTTGAGGGGTCTTATCATGGAATAACT
GCCGGTACTTTGGGTCTCACCGGTGCTAATAGATTTAAGGAATTTCAGCCATTTTTTGATGATAGAGTAGTAAAGTTTCC
ATATCCATATCCTTATAGGTGCCCATTCAAAGACTGTCTGAACGAGACATTAAGCTTACTAGACTATGCAATGTCAAATC
CGGGTTATTTAGGAGGAGATGTAGCTGGTATATTAGTGGAGCCAATACAAGGAGAAGGTGGCTATGTAGTTCCACCTAAG
GGTTTCCTTAAAGGCCTAAAAGAACTAGCTGAAAAGTATTCAGTACCACTAATAGTAGATGAAGTACAGACTGGTGTGGG
AAGGACTGGAAAAATGTGGGCTTATCAGTGGGAAAATATTGAACCGGATATAGTGACAATTTCCAAAGCAATAGGTGAGG
GAATACCAGTTTCAATGGTAGCATATAGGGAAGACTTTGATAAACTACCAACTGGGTTTCACCTCGGTACCTACAGAGGA
AATCCCTTAGGACTTGCAGCCGGGTTAGCTTCTTTAGAATTCATAGAGAGTCATAACATCCTTTCCAGAGTTGAGAGATT
GGGTAGGAAAGCCTTAGAATTATTGAAAGAAGTTCAAAATCCACATGTAGGCGATATAAGGGGTTTGGGCTTTATGATAG
GAATAGAGTTAGTTAAGGACAGTAAGGAACCATGGAGCGAAGGAACAAAGGTAGTTATAGAACGAGCGTTAAAGAGAGGG
TTGTTGGTTTATAAGGCAGGTAGATGGGACAACGTAATAAGGTTAATGCCACCATTAACTATCCCAGAGTCATTACTTGA
TAGGGCAATAGAAATTTTAAAGATAATACTTAACACACTTTAG

Upstream 100 bases:

>100_bases
CGGAATTAGAAGTGGTTAAAAGTAAGCAGAAGTTACGCCACGGGTAAACACTAAATATCGGTAGCTGATCATTTTTAAAC
AGTGCTAGATAAGTTAGTAT

Downstream 100 bases:

>100_bases
CATTTTTTTAAAAAATGTATAATTGTTTGTGTGTTAAAGCTTATTATTCTTATTTAACTCTAGATACATGGATGCTTGAT
GGAGAAGTCTAAAAAGGGAG

Product: 4-aminobutyrate aminotransferase (gabT-1)

Products: NA

Alternate protein names: Diaminobutyrate transaminase; L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase; DABA aminotransferase; DABA-AT; L-diaminobutyric acid transaminase [H]

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MEENLDSSVLEAPIINVTPPGSKSLKLLKDQEEYETSAINYPKYFKIAIDKAQGSTVTDVDGNVYIDLVTGISVVNLGHN
NPFVRKRVQEQLEKVWHTLEVPTEIRVNFSKKLLSTLGMRAKLLFTTTGADAVEAAVKIARFITGKKTIIAFEGSYHGIT
AGTLGLTGANRFKEFQPFFDDRVVKFPYPYPYRCPFKDCLNETLSLLDYAMSNPGYLGGDVAGILVEPIQGEGGYVVPPK
GFLKGLKELAEKYSVPLIVDEVQTGVGRTGKMWAYQWENIEPDIVTISKAIGEGIPVSMVAYREDFDKLPTGFHLGTYRG
NPLGLAAGLASLEFIESHNILSRVERLGRKALELLKEVQNPHVGDIRGLGFMIGIELVKDSKEPWSEGTKVVIERALKRG
LLVYKAGRWDNVIRLMPPLTIPESLLDRAIEILKIILNTL

Sequences:

>Translated_440_residues
MEENLDSSVLEAPIINVTPPGSKSLKLLKDQEEYETSAINYPKYFKIAIDKAQGSTVTDVDGNVYIDLVTGISVVNLGHN
NPFVRKRVQEQLEKVWHTLEVPTEIRVNFSKKLLSTLGMRAKLLFTTTGADAVEAAVKIARFITGKKTIIAFEGSYHGIT
AGTLGLTGANRFKEFQPFFDDRVVKFPYPYPYRCPFKDCLNETLSLLDYAMSNPGYLGGDVAGILVEPIQGEGGYVVPPK
GFLKGLKELAEKYSVPLIVDEVQTGVGRTGKMWAYQWENIEPDIVTISKAIGEGIPVSMVAYREDFDKLPTGFHLGTYRG
NPLGLAAGLASLEFIESHNILSRVERLGRKALELLKEVQNPHVGDIRGLGFMIGIELVKDSKEPWSEGTKVVIERALKRG
LLVYKAGRWDNVIRLMPPLTIPESLLDRAIEILKIILNTL
>Mature_440_residues
MEENLDSSVLEAPIINVTPPGSKSLKLLKDQEEYETSAINYPKYFKIAIDKAQGSTVTDVDGNVYIDLVTGISVVNLGHN
NPFVRKRVQEQLEKVWHTLEVPTEIRVNFSKKLLSTLGMRAKLLFTTTGADAVEAAVKIARFITGKKTIIAFEGSYHGIT
AGTLGLTGANRFKEFQPFFDDRVVKFPYPYPYRCPFKDCLNETLSLLDYAMSNPGYLGGDVAGILVEPIQGEGGYVVPPK
GFLKGLKELAEKYSVPLIVDEVQTGVGRTGKMWAYQWENIEPDIVTISKAIGEGIPVSMVAYREDFDKLPTGFHLGTYRG
NPLGLAAGLASLEFIESHNILSRVERLGRKALELLKEVQNPHVGDIRGLGFMIGIELVKDSKEPWSEGTKVVIERALKRG
LLVYKAGRWDNVIRLMPPLTIPESLLDRAIEILKIILNTL

Specific function: Unknown

COG id: COG0160

COG function: function code E; 4-aminobutyrate aminotransferase and related aminotransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI13994255, Length=460, Percent_Identity=30.6521739130435, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI37574042, Length=417, Percent_Identity=29.4964028776978, Blast_Score=176, Evalue=5e-44,
Organism=Homo sapiens, GI4557809, Length=423, Percent_Identity=32.6241134751773, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI226442705, Length=417, Percent_Identity=29.0167865707434, Blast_Score=165, Evalue=7e-41,
Organism=Homo sapiens, GI226442709, Length=387, Percent_Identity=29.4573643410853, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI24119277, Length=402, Percent_Identity=27.8606965174129, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI284507298, Length=327, Percent_Identity=34.8623853211009, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI188536080, Length=479, Percent_Identity=25.8872651356994, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI38679950, Length=479, Percent_Identity=25.8872651356994, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI38679946, Length=479, Percent_Identity=25.8872651356994, Blast_Score=109, Evalue=6e-24,
Organism=Escherichia coli, GI1787560, Length=399, Percent_Identity=37.34335839599, Blast_Score=230, Evalue=1e-61,
Organism=Escherichia coli, GI1789016, Length=399, Percent_Identity=35.8395989974937, Blast_Score=230, Evalue=1e-61,
Organism=Escherichia coli, GI145693181, Length=402, Percent_Identity=32.8358208955224, Blast_Score=198, Evalue=5e-52,
Organism=Escherichia coli, GI1788044, Length=383, Percent_Identity=34.4647519582245, Blast_Score=195, Evalue=4e-51,
Organism=Escherichia coli, GI1789759, Length=392, Percent_Identity=30.6122448979592, Blast_Score=179, Evalue=4e-46,
Organism=Escherichia coli, GI1786349, Length=369, Percent_Identity=31.7073170731707, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1786991, Length=400, Percent_Identity=25.5, Blast_Score=86, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI32564660, Length=421, Percent_Identity=31.5914489311164, Blast_Score=197, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI25144271, Length=428, Percent_Identity=31.3084112149533, Blast_Score=170, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI71992977, Length=425, Percent_Identity=28.2352941176471, Blast_Score=165, Evalue=6e-41,
Organism=Caenorhabditis elegans, GI25144274, Length=216, Percent_Identity=36.1111111111111, Blast_Score=129, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17541228, Length=484, Percent_Identity=27.2727272727273, Blast_Score=125, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6324432, Length=427, Percent_Identity=30.6791569086651, Blast_Score=173, Evalue=5e-44,
Organism=Saccharomyces cerevisiae, GI6323470, Length=434, Percent_Identity=31.7972350230415, Blast_Score=173, Evalue=5e-44,
Organism=Saccharomyces cerevisiae, GI6321456, Length=484, Percent_Identity=27.4793388429752, Blast_Score=112, Evalue=1e-25,
Organism=Drosophila melanogaster, GI28574759, Length=461, Percent_Identity=29.9349240780911, Blast_Score=198, Evalue=6e-51,
Organism=Drosophila melanogaster, GI161085790, Length=458, Percent_Identity=30.1310043668122, Blast_Score=196, Evalue=3e-50,
Organism=Drosophila melanogaster, GI21357415, Length=425, Percent_Identity=29.4117647058824, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI21356575, Length=399, Percent_Identity=28.0701754385965, Blast_Score=142, Evalue=7e-34,
Organism=Drosophila melanogaster, GI281366494, Length=413, Percent_Identity=28.3292978208232, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24667139, Length=413, Percent_Identity=28.3292978208232, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24667143, Length=413, Percent_Identity=28.3292978208232, Blast_Score=114, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR004637
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.76 [H]

Molecular weight: Translated: 48782; Mature: 48782

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEENLDSSVLEAPIINVTPPGSKSLKLLKDQEEYETSAINYPKYFKIAIDKAQGSTVTDV
CCCCCCCHHHHCCEEEECCCCCCCHHHHCCHHHHHHHHCCCCCEEEEEEECCCCCEEEEC
DGNVYIDLVTGISVVNLGHNNPFVRKRVQEQLEKVWHTLEVPTEIRVNFSKKLLSTLGMR
CCCEEEEEECCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHEEECHHHHHHHHHCCC
AKLLFTTTGADAVEAAVKIARFITGKKTIIAFEGSYHGITAGTLGLTGANRFKEFQPFFD
EEEEEEECCHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEECCCCCCCCHHHHHHCCCCC
DRVVKFPYPYPYRCPFKDCLNETLSLLDYAMSNPGYLGGDVAGILVEPIQGEGGYVVPPK
CCEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEECCCCEEECCH
GFLKGLKELAEKYSVPLIVDEVQTGVGRTGKMWAYQWENIEPDIVTISKAIGEGIPVSMV
HHHHHHHHHHHHCCCCEEEEHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCCEEHH
AYREDFDKLPTGFHLGTYRGNPLGLAAGLASLEFIESHNILSRVERLGRKALELLKEVQN
HHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PHVGDIRGLGFMIGIELVKDSKEPWSEGTKVVIERALKRGLLVYKAGRWDNVIRLMPPLT
CCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCCEECCCCC
IPESLLDRAIEILKIILNTL
CCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEENLDSSVLEAPIINVTPPGSKSLKLLKDQEEYETSAINYPKYFKIAIDKAQGSTVTDV
CCCCCCCHHHHCCEEEECCCCCCCHHHHCCHHHHHHHHCCCCCEEEEEEECCCCCEEEEC
DGNVYIDLVTGISVVNLGHNNPFVRKRVQEQLEKVWHTLEVPTEIRVNFSKKLLSTLGMR
CCCEEEEEECCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHEEECHHHHHHHHHCCC
AKLLFTTTGADAVEAAVKIARFITGKKTIIAFEGSYHGITAGTLGLTGANRFKEFQPFFD
EEEEEEECCHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEECCCCCCCCHHHHHHCCCCC
DRVVKFPYPYPYRCPFKDCLNETLSLLDYAMSNPGYLGGDVAGILVEPIQGEGGYVVPPK
CCEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEECCCCEEECCH
GFLKGLKELAEKYSVPLIVDEVQTGVGRTGKMWAYQWENIEPDIVTISKAIGEGIPVSMV
HHHHHHHHHHHHCCCCEEEEHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCCEEHH
AYREDFDKLPTGFHLGTYRGNPLGLAAGLASLEFIESHNILSRVERLGRKALELLKEVQN
HHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PHVGDIRGLGFMIGIELVKDSKEPWSEGTKVVIERALKRGLLVYKAGRWDNVIRLMPPLT
CCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCCEECCCCC
IPESLLDRAIEILKIILNTL
CCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11274118; 11481432 [H]