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The map label for this gene is nagA [H]

Identifier: 15899396

GI number: 15899396

Start: 2430019

End: 2431206

Strand: Direct

Name: nagA [H]

Synonym: SSO2673

Alternate gene names: 15899396

Gene position: 2430019-2431206 (Clockwise)

Preceding gene: 15899395

Following gene: 15899398

Centisome position: 81.21

GC content: 33.92

Gene sequence:

>1188_bases
TTGCAATGGATATATGCAAAAATGAAGAGCCCAAATTATTTAAATACTCGCATGAAGTTGCGTGTTTCTTATACGGTAAG
GTGGGTGAAAGTGAGTAAGTGTATCAGAGGACTAGAGATAATAACCCCATTAGAAAGTTTTAGGGATGACATAGTAATAT
CTGATGGTGAAATAAGGAAAATTGGAAGTGGAATCTGCAATGAGGAAATAAAAGTAGATAGAGGTAAATATGTAATACCT
GGAATGATTGATATTCATACTCACGGTATAGGGGGAATTCTTGTAAATGACATTAGAAGTATTAATGACTATGAGAAAAT
GGTATCCTATTATTATTCACATGGTGTAACCACTTTCATTCCATCAACAATTTCTGAAAATGTTGAAAAATTAGTGAGTA
TAGCAAGGGTTTTAAATGAAGTTAAAAGTATTGGGATACACCTTGAGGGACCGTTAATAAATCCGAATAGAGCTGGTGCA
CATAAATTCTTTACTAGATTCGACGAACGAATTTTAGAAATTTCTAAACTCTTTAAAATAAAGAGAATTACTATAGCACC
AGAGATTTTGAGTGATAAAGAATTAGAGAATTTAGCGGATAACTTTCAAGTTTCTTTAGGTCATACGGACGCTAATTCAG
ATGATACCAGAAGAGCTATAGGTTTTGGAGCATCATCAGTTACACATTTGTTCAATGCTATGAGGCCATTCCATCATAGA
GATCCCGGAATAATTGGTGTTTCGTTAACTTCTCCGATATACGCTGAAGTAATATCAGATTTGGTACACATTAATGAGAT
TACACTAAGTATTGTAAGTAAGTTAAAGGGGGATAAGACAATTCTAGTGACTGATTCCTTACAAGCTGCGGGATTAGGCG
AAGGAGAATTTTTACTATATGGAGAAAAAATTACTTGCGATAAGGCTTGTTTCGAGGCTAATAAAAGGCTTGTAGGTAGT
AACATAACTTTGGATGAAGGCGTGAGACGTGTTAGTAAAATAATTGGATTAAGAGAAGCGATAAAATATGTAACGTATTC
TCCAGCATCTCTACTTAACTTAGAAAAAATAGGACAGATATCTAGGGGTTATGTTGCAGATTTAGTTATATTGGATGAAA
ACCTCAATGTGCTCACAACGTTAAAAAGTGGTAGTATAGTCTTCTCCATCTTTAAAAATTCATCATAA

Upstream 100 bases:

>100_bases
AAGCTCACACCATCTATTGATAATCTATATAAAGAGATTAACGTTAAGATAAATTACGAGAGAGTAGAAAAGGGATGCCC
ATATAGGCTAAGATGTCCTT

Downstream 100 bases:

>100_bases
AAACAAGGATAATTCATTACTCATATACAAATTCATAATAATATTCATGATATTCTTATTAAATAATTTTTAACGTATTT
TGTCTAACGCTAATTTCAAT

Product: N-acetylglucosamine-6-phosphate deacetylase (nagA)

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MQWIYAKMKSPNYLNTRMKLRVSYTVRWVKVSKCIRGLEIITPLESFRDDIVISDGEIRKIGSGICNEEIKVDRGKYVIP
GMIDIHTHGIGGILVNDIRSINDYEKMVSYYYSHGVTTFIPSTISENVEKLVSIARVLNEVKSIGIHLEGPLINPNRAGA
HKFFTRFDERILEISKLFKIKRITIAPEILSDKELENLADNFQVSLGHTDANSDDTRRAIGFGASSVTHLFNAMRPFHHR
DPGIIGVSLTSPIYAEVISDLVHINEITLSIVSKLKGDKTILVTDSLQAAGLGEGEFLLYGEKITCDKACFEANKRLVGS
NITLDEGVRRVSKIIGLREAIKYVTYSPASLLNLEKIGQISRGYVADLVILDENLNVLTTLKSGSIVFSIFKNSS

Sequences:

>Translated_395_residues
MQWIYAKMKSPNYLNTRMKLRVSYTVRWVKVSKCIRGLEIITPLESFRDDIVISDGEIRKIGSGICNEEIKVDRGKYVIP
GMIDIHTHGIGGILVNDIRSINDYEKMVSYYYSHGVTTFIPSTISENVEKLVSIARVLNEVKSIGIHLEGPLINPNRAGA
HKFFTRFDERILEISKLFKIKRITIAPEILSDKELENLADNFQVSLGHTDANSDDTRRAIGFGASSVTHLFNAMRPFHHR
DPGIIGVSLTSPIYAEVISDLVHINEITLSIVSKLKGDKTILVTDSLQAAGLGEGEFLLYGEKITCDKACFEANKRLVGS
NITLDEGVRRVSKIIGLREAIKYVTYSPASLLNLEKIGQISRGYVADLVILDENLNVLTTLKSGSIVFSIFKNSS
>Mature_395_residues
MQWIYAKMKSPNYLNTRMKLRVSYTVRWVKVSKCIRGLEIITPLESFRDDIVISDGEIRKIGSGICNEEIKVDRGKYVIP
GMIDIHTHGIGGILVNDIRSINDYEKMVSYYYSHGVTTFIPSTISENVEKLVSIARVLNEVKSIGIHLEGPLINPNRAGA
HKFFTRFDERILEISKLFKIKRITIAPEILSDKELENLADNFQVSLGHTDANSDDTRRAIGFGASSVTHLFNAMRPFHHR
DPGIIGVSLTSPIYAEVISDLVHINEITLSIVSKLKGDKTILVTDSLQAAGLGEGEFLLYGEKITCDKACFEANKRLVGS
NITLDEGVRRVSKIIGLREAIKYVTYSPASLLNLEKIGQISRGYVADLVILDENLNVLTTLKSGSIVFSIFKNSS

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=418, Percent_Identity=30.1435406698565, Blast_Score=146, Evalue=4e-35,
Organism=Homo sapiens, GI224922791, Length=416, Percent_Identity=30.0480769230769, Blast_Score=145, Evalue=5e-35,
Organism=Escherichia coli, GI1786892, Length=368, Percent_Identity=29.6195652173913, Blast_Score=149, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI17553768, Length=357, Percent_Identity=29.6918767507003, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI19920392, Length=377, Percent_Identity=33.9522546419098, Blast_Score=159, Evalue=2e-39,
Organism=Drosophila melanogaster, GI281361140, Length=390, Percent_Identity=33.3333333333333, Blast_Score=154, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 44034; Mature: 44034

Theoretical pI: Translated: 8.55; Mature: 8.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQWIYAKMKSPNYLNTRMKLRVSYTVRWVKVSKCIRGLEIITPLESFRDDIVISDGEIRK
CCEEEEECCCCCEECCEEEEEEEEEEEHEEHHHHHCCHHHHCCHHHHCCCEEECCCCHHH
IGSGICNEEIKVDRGKYVIPGMIDIHTHGIGGILVNDIRSINDYEKMVSYYYSHGVTTFI
HHCCCCCCCEEECCCCEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHCC
PSTISENVEKLVSIARVLNEVKSIGIHLEGPLINPNRAGAHKFFTRFDERILEISKLFKI
CHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
KRITIAPEILSDKELENLADNFQVSLGHTDANSDDTRRAIGFGASSVTHLFNAMRPFHHR
HEEEECHHHHCHHHHHHHHCCEEEEECCCCCCCCCHHHHHHCCHHHHHHHHHHHCCCCCC
DPGIIGVSLTSPIYAEVISDLVHINEITLSIVSKLKGDKTILVTDSLQAAGLGEGEFLLY
CCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCEEEE
GEKITCDKACFEANKRLVGSNITLDEGVRRVSKIIGLREAIKYVTYSPASLLNLEKIGQI
CCEECHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCHHHHCCC
SRGYVADLVILDENLNVLTTLKSGSIVFSIFKNSS
CCCCEEEEEEEECCCCEEEEECCCCEEEEEECCCC
>Mature Secondary Structure
MQWIYAKMKSPNYLNTRMKLRVSYTVRWVKVSKCIRGLEIITPLESFRDDIVISDGEIRK
CCEEEEECCCCCEECCEEEEEEEEEEEHEEHHHHHCCHHHHCCHHHHCCCEEECCCCHHH
IGSGICNEEIKVDRGKYVIPGMIDIHTHGIGGILVNDIRSINDYEKMVSYYYSHGVTTFI
HHCCCCCCCEEECCCCEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHCC
PSTISENVEKLVSIARVLNEVKSIGIHLEGPLINPNRAGAHKFFTRFDERILEISKLFKI
CHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
KRITIAPEILSDKELENLADNFQVSLGHTDANSDDTRRAIGFGASSVTHLFNAMRPFHHR
HEEEECHHHHCHHHHHHHHCCEEEEECCCCCCCCCHHHHHHCCHHHHHHHHHHHCCCCCC
DPGIIGVSLTSPIYAEVISDLVHINEITLSIVSKLKGDKTILVTDSLQAAGLGEGEFLLY
CCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCEEEE
GEKITCDKACFEANKRLVGSNITLDEGVRRVSKIIGLREAIKYVTYSPASLLNLEKIGQI
CCEECHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCHHHHCCC
SRGYVADLVILDENLNVLTTLKSGSIVFSIFKNSS
CCCCEEEEEEEECCCCEEEEECCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA