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The map label for this gene is yqjP [H]

Identifier: 15899251

GI number: 15899251

Start: 2283385

End: 2284317

Strand: Reverse

Name: yqjP [H]

Synonym: SSO2515

Alternate gene names: 15899251

Gene position: 2284317-2283385 (Counterclockwise)

Preceding gene: 15899255

Following gene: 15899250

Centisome position: 76.34

GC content: 35.05

Gene sequence:

>933_bases
GTGACGATATTTACTTTAAAGTTACCAATGCAAGGCCCCTTGAAGTACATAAACTCATATTTAGTAAAAGGCAATGAAGA
GAGCGTACTGATTGATACTGGACTACCTACTCAAGAAGATGTGACTACTTTATCAAATTATTTGAAAGCTTATGGTTATC
CGAACTTCGTAGTAATCACTCATTACCATCCAGATCATATGGGCTTAGTTAGATTGTTTAAGGATAAGAGTATTATATTG
ATATCTGATAGGGAGTTAGAATATGTAACCTATCTACTAAGTGAGGAGTATGAAAAGGAAATGAGGAAATATCTTCTCGC
TAATGGTTTTCCAGAAGAGTTTATTCAGAGAATGTTTAGAAATAGAAGTAGATTTAGTGAAATCATTGACGGCGTAAATT
TCAATACCGTTAAGGATGGAGATGTGATAAAATTAGGCCAAGAACAAATGAGGGTATTATTGACTCCAGGCCATACTATG
GGACACATTTGCCTAGTTTACGAAAAGGTAGTATTCTGTGGAGATCATATATTGCAAGATATAACGCCAAATATATCGTT
ACTTAGATTAGAGGATAATCCGTTAAAGGCTTATTTAGAAAGCCTTGATAAGGTACAAAAACTGGATATTGAACTGCTTT
ATCCCGCACATGGAGAAGTACTCAAAGATGTGAGTAAAAGGGTAGAGGAAATAAAGGAGCACCATAAAAGACGGCTAGAG
GAAATAATGAACATTATAAGGACTTTAGGAAAAACTAGTGGATTTAATATTGCGTCCAGAATTTCTTGGTACAAGAAGTG
GGATGAACTTTCCGCTTTTGATAAACAATTAGCAATGGGGGAAACATTGGCACATATTAAATATCTAGTCGAGGAGGGCT
TTATAAGAGAGGTAAACGCTAGTGGTAGTATTTATTATACTATGAGTAGTTGA

Upstream 100 bases:

>100_bases
TTAGTTAGCTATTTATTTAATTTTTAATAGTAAAAAGAGTAAAATGAGTTTATTGGATTAAGGAGATAAATTTTAAAGCT
AGTCAAGAGAGAATGAGTTT

Downstream 100 bases:

>100_bases
TATAAAATGAGTAAATATTTAAAATTGTAGGAAGATTGAATTGAGATTACTTTTTAACCTTATTTTGCTTATCTTTATCC
GATGAAAGTAGAAGATATTA

Product: hypothetical protein

Products: Reduced glutathione; H+; D-Lactate [C]

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MTIFTLKLPMQGPLKYINSYLVKGNEESVLIDTGLPTQEDVTTLSNYLKAYGYPNFVVITHYHPDHMGLVRLFKDKSIIL
ISDRELEYVTYLLSEEYEKEMRKYLLANGFPEEFIQRMFRNRSRFSEIIDGVNFNTVKDGDVIKLGQEQMRVLLTPGHTM
GHICLVYEKVVFCGDHILQDITPNISLLRLEDNPLKAYLESLDKVQKLDIELLYPAHGEVLKDVSKRVEEIKEHHKRRLE
EIMNIIRTLGKTSGFNIASRISWYKKWDELSAFDKQLAMGETLAHIKYLVEEGFIREVNASGSIYYTMSS

Sequences:

>Translated_310_residues
MTIFTLKLPMQGPLKYINSYLVKGNEESVLIDTGLPTQEDVTTLSNYLKAYGYPNFVVITHYHPDHMGLVRLFKDKSIIL
ISDRELEYVTYLLSEEYEKEMRKYLLANGFPEEFIQRMFRNRSRFSEIIDGVNFNTVKDGDVIKLGQEQMRVLLTPGHTM
GHICLVYEKVVFCGDHILQDITPNISLLRLEDNPLKAYLESLDKVQKLDIELLYPAHGEVLKDVSKRVEEIKEHHKRRLE
EIMNIIRTLGKTSGFNIASRISWYKKWDELSAFDKQLAMGETLAHIKYLVEEGFIREVNASGSIYYTMSS
>Mature_309_residues
TIFTLKLPMQGPLKYINSYLVKGNEESVLIDTGLPTQEDVTTLSNYLKAYGYPNFVVITHYHPDHMGLVRLFKDKSIILI
SDRELEYVTYLLSEEYEKEMRKYLLANGFPEEFIQRMFRNRSRFSEIIDGVNFNTVKDGDVIKLGQEQMRVLLTPGHTMG
HICLVYEKVVFCGDHILQDITPNISLLRLEDNPLKAYLESLDKVQKLDIELLYPAHGEVLKDVSKRVEEIKEHHKRRLEE
IMNIIRTLGKTSGFNIASRISWYKKWDELSAFDKQLAMGETLAHIKYLVEEGFIREVNASGSIYYTMSS

Specific function: Thiolesterase That Catalyzes The Hydrolysis Of S-D- Lactoyl-Glutathione To Form Glutathione And D-Lactic Acid. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI7705793, Length=242, Percent_Identity=28.9256198347107, Blast_Score=85, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI193205216, Length=262, Percent_Identity=27.0992366412214, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17537503, Length=262, Percent_Identity=27.0992366412214, Blast_Score=83, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: 3.1.2.6 [C]

Molecular weight: Translated: 35985; Mature: 35854

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIFTLKLPMQGPLKYINSYLVKGNEESVLIDTGLPTQEDVTTLSNYLKAYGYPNFVVIT
CEEEEEECCCCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEE
HYHPDHMGLVRLFKDKSIILISDRELEYVTYLLSEEYEKEMRKYLLANGFPEEFIQRMFR
EECCCHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
NRSRFSEIIDGVNFNTVKDGDVIKLGQEQMRVLLTPGHTMGHICLVYEKVVFCGDHILQD
HHHHHHHHHCCCCCCEECCCCEEEECHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
ITPNISLLRLEDNPLKAYLESLDKVQKLDIELLYPAHGEVLKDVSKRVEEIKEHHKRRLE
CCCCCEEEEECCCHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
EIMNIIRTLGKTSGFNIASRISWYKKWDELSAFDKQLAMGETLAHIKYLVEEGFIREVNA
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECC
SGSIYYTMSS
CCEEEEEECC
>Mature Secondary Structure 
TIFTLKLPMQGPLKYINSYLVKGNEESVLIDTGLPTQEDVTTLSNYLKAYGYPNFVVIT
EEEEEECCCCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEE
HYHPDHMGLVRLFKDKSIILISDRELEYVTYLLSEEYEKEMRKYLLANGFPEEFIQRMFR
EECCCHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
NRSRFSEIIDGVNFNTVKDGDVIKLGQEQMRVLLTPGHTMGHICLVYEKVVFCGDHILQD
HHHHHHHHHCCCCCCEECCCCEEEECHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
ITPNISLLRLEDNPLKAYLESLDKVQKLDIELLYPAHGEVLKDVSKRVEEIKEHHKRRLE
CCCCCEEEEECCCHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
EIMNIIRTLGKTSGFNIASRISWYKKWDELSAFDKQLAMGETLAHIKYLVEEGFIREVNA
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECC
SGSIYYTMSS
CCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: H2O; (R)-S-Lactoylglutathione [C]

Specific reaction: H2O + (R)-S-Lactoylglutathione --> Reduced glutathione + H+ + D-Lactate [C]

General reaction: Thioester hydrolysis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]