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The map label for this gene is acaB-6

Identifier: 15899246

GI number: 15899246

Start: 2276632

End: 2277774

Strand: Direct

Name: acaB-6

Synonym: SSO2508

Alternate gene names: NA

Gene position: 2276632-2277774 (Clockwise)

Preceding gene: 15899244

Following gene: 15899247

Centisome position: 76.08

GC content: 38.15

Gene sequence:

>1143_bases
ATGATTGTAGGATTTGCCGGAAAACTATATAAAAACTATGAGAAAGATGGTATAGAGTTATTGAAAGAGGTCACTGATGA
GGCACTAGATATTGCTGGATTGAATTACGCTGACGTCGATGGGATAATGGCTAACATCGGAAGAGGCTCATTTCACGGTA
ATAGGACATATCTTAATCCTCCTGCCCAAATAAGTGAATATTTTGGAATAAAGCCGAAAATTATAGAACATGTCCAATAC
GGAGGACCTTCAGTATTGTCAATGATATATAGGGCTTACAAGGCAATCAAGGCGGGGGATGCGGAGACAATACTTTGCAT
ACAAGGAGGGAAAATATCTCATTTAAGAGACAATCATTTCCAAAAAACAGATATAATTGATAGTCCCTTTGATGAGTACA
TTAAGATTTATGACCAGATGTCTCCAATATCTGATTACGCAATGGTTGCTTATAGACATTCTAAACTCTTCGGTACAACT
GACGAACAAAGGGCACGTATTGCAGTGATCCAGAGATATAATGCAAGTTATAATCCTAAAGCTCTGTTCAGAAATCCTAT
TACAGTCGAAGATGTTTTGAAATCTAGGATAGTTTCTTATCCTTTACATCTTCTTGAAATAGTTTACCCTATAGACGGTT
TTCACGTTTTTGTGGTAAGTAAAAGGAGTAGTAAGTCAGCCCTTAGAAATATTGACATTTTAGCGTATGGAGAGGCCCAT
TGGCCAAATCCACCAGCTGAATGGGATGATATAATTTATACTCCAACAACTGAAAGCGCAAAAAGGGCTTCATTTGACCT
AAACCGGGTAGATGCCTTTCAACTCTACGACTCATTCACCATAACTGTGATGCTACAAATGGAGGACATAGGGTTAGTTG
AGAAAGGTAAGGTTGGACAGTTCGTAGAATCTCATGATTTATCATTTAAGGGCGATGTTCCAATTAATACTGGGGGAGGT
AGTTTAAATACTGGTCAGCCCGCATACATGAGTGGTGGTGTTATTTTAGAGGAGGCATTACTTCAATTAAACGATATGGC
TAATGGTCATCAAGTTAAAGGTGCAAATGTTATATTTTTAAATGGAATTGGGTGGTGGAGTAGAAGGCACAGTGTAACTT
TAGTATTGGGTGAGCGAAAATGA

Upstream 100 bases:

>100_bases
GATATCCGAATCGCCCTCTTAATTCTTTGTAAAATTCAACTACCTTACAAAACAGAAATTTGAACAAGGTTTTTTAATAG
GTAGTAAATTATGATTAACG

Downstream 100 bases:

>100_bases
GGGAAGAAGAAATAAGAGAATTATATTTTAAGTATTTCGATGAGAATAAGTTACCGTTTATTCAGTGCAATAAATGTGGC
CATAAGTTTTACTATCCAAG

Product: Acetyl-CoA c-acetyltransferase (acetoacetyl-CoA thiolase) (acaB-6)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MIVGFAGKLYKNYEKDGIELLKEVTDEALDIAGLNYADVDGIMANIGRGSFHGNRTYLNPPAQISEYFGIKPKIIEHVQY
GGPSVLSMIYRAYKAIKAGDAETILCIQGGKISHLRDNHFQKTDIIDSPFDEYIKIYDQMSPISDYAMVAYRHSKLFGTT
DEQRARIAVIQRYNASYNPKALFRNPITVEDVLKSRIVSYPLHLLEIVYPIDGFHVFVVSKRSSKSALRNIDILAYGEAH
WPNPPAEWDDIIYTPTTESAKRASFDLNRVDAFQLYDSFTITVMLQMEDIGLVEKGKVGQFVESHDLSFKGDVPINTGGG
SLNTGQPAYMSGGVILEEALLQLNDMANGHQVKGANVIFLNGIGWWSRRHSVTLVLGERK

Sequences:

>Translated_380_residues
MIVGFAGKLYKNYEKDGIELLKEVTDEALDIAGLNYADVDGIMANIGRGSFHGNRTYLNPPAQISEYFGIKPKIIEHVQY
GGPSVLSMIYRAYKAIKAGDAETILCIQGGKISHLRDNHFQKTDIIDSPFDEYIKIYDQMSPISDYAMVAYRHSKLFGTT
DEQRARIAVIQRYNASYNPKALFRNPITVEDVLKSRIVSYPLHLLEIVYPIDGFHVFVVSKRSSKSALRNIDILAYGEAH
WPNPPAEWDDIIYTPTTESAKRASFDLNRVDAFQLYDSFTITVMLQMEDIGLVEKGKVGQFVESHDLSFKGDVPINTGGG
SLNTGQPAYMSGGVILEEALLQLNDMANGHQVKGANVIFLNGIGWWSRRHSVTLVLGERK
>Mature_380_residues
MIVGFAGKLYKNYEKDGIELLKEVTDEALDIAGLNYADVDGIMANIGRGSFHGNRTYLNPPAQISEYFGIKPKIIEHVQY
GGPSVLSMIYRAYKAIKAGDAETILCIQGGKISHLRDNHFQKTDIIDSPFDEYIKIYDQMSPISDYAMVAYRHSKLFGTT
DEQRARIAVIQRYNASYNPKALFRNPITVEDVLKSRIVSYPLHLLEIVYPIDGFHVFVVSKRSSKSALRNIDILAYGEAH
WPNPPAEWDDIIYTPTTESAKRASFDLNRVDAFQLYDSFTITVMLQMEDIGLVEKGKVGQFVESHDLSFKGDVPINTGGG
SLNTGQPAYMSGGVILEEALLQLNDMANGHQVKGANVIFLNGIGWWSRRHSVTLVLGERK

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI19923233, Length=368, Percent_Identity=22.2826086956522, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI302344760, Length=295, Percent_Identity=22.3728813559322, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI302344767, Length=295, Percent_Identity=22.3728813559322, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI19921506, Length=369, Percent_Identity=22.7642276422764, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24585051, Length=369, Percent_Identity=22.4932249322493, Blast_Score=82, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: NA

Molecular weight: Translated: 42507; Mature: 42507

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVGFAGKLYKNYEKDGIELLKEVTDEALDIAGLNYADVDGIMANIGRGSFHGNRTYLNP
CEECCCHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCEEECC
PAQISEYFGIKPKIIEHVQYGGPSVLSMIYRAYKAIKAGDAETILCIQGGKISHLRDNHF
CHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCC
QKTDIIDSPFDEYIKIYDQMSPISDYAMVAYRHSKLFGTTDEQRARIAVIQRYNASYNPK
CCCCCCCCCHHHHHHHHHHCCCHHHHHHHEEEHHHHCCCCCHHHHHEEEEEECCCCCCCH
ALFRNPITVEDVLKSRIVSYPLHLLEIVYPIDGFHVFVVSKRSSKSALRNIDILAYGEAH
HEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHCCEEEEECCCC
WPNPPAEWDDIIYTPTTESAKRASFDLNRVDAFQLYDSFTITVMLQMEDIGLVEKGKVGQ
CCCCCCCCCCEEECCCCCCHHHCCCCCCCCHHHHEECCEEEEEEEEECCCCCCCCCCCCC
FVESHDLSFKGDVPINTGGGSLNTGQPAYMSGGVILEEALLQLNDMANGHQVKGANVIFL
HHHHCCCCEECCCCEECCCCCCCCCCCCEEECCHHHHHHHHHHHCCCCCCEECCCCEEEE
NGIGWWSRRHSVTLVLGERK
ECCCCCCCCCEEEEEEECCC
>Mature Secondary Structure
MIVGFAGKLYKNYEKDGIELLKEVTDEALDIAGLNYADVDGIMANIGRGSFHGNRTYLNP
CEECCCHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCEEECC
PAQISEYFGIKPKIIEHVQYGGPSVLSMIYRAYKAIKAGDAETILCIQGGKISHLRDNHF
CHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCC
QKTDIIDSPFDEYIKIYDQMSPISDYAMVAYRHSKLFGTTDEQRARIAVIQRYNASYNPK
CCCCCCCCCHHHHHHHHHHCCCHHHHHHHEEEHHHHCCCCCHHHHHEEEEEECCCCCCCH
ALFRNPITVEDVLKSRIVSYPLHLLEIVYPIDGFHVFVVSKRSSKSALRNIDILAYGEAH
HEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHCCEEEEECCCC
WPNPPAEWDDIIYTPTTESAKRASFDLNRVDAFQLYDSFTITVMLQMEDIGLVEKGKVGQ
CCCCCCCCCCEEECCCCCCHHHCCCCCCCCHHHHEECCEEEEEEEEECCCCCCCCCCCCC
FVESHDLSFKGDVPINTGGGSLNTGQPAYMSGGVILEEALLQLNDMANGHQVKGANVIFL
HHHHCCCCEECCCCEECCCCCCCCCCCCEEECCHHHHHHHHHHHCCCCCCEECCCCEEEE
NGIGWWSRRHSVTLVLGERK
ECCCCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]