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The map label for this gene is adh-9 [H]

Identifier: 15899240

GI number: 15899240

Start: 2269483

End: 2270529

Strand: Reverse

Name: adh-9 [H]

Synonym: SSO2501

Alternate gene names: 15899240

Gene position: 2270529-2269483 (Counterclockwise)

Preceding gene: 15899241

Following gene: 15899239

Centisome position: 75.88

GC content: 38.59

Gene sequence:

>1047_bases
ATGAAAGCAGCCGTATATAAAGGGTATGGATTACCATTAGAAATAGAAGAAGTTCCCAATCCAGCTCCAAAAGAAGGAGA
AGTCTTAGTGAAAGTAGCATCGACCGGAATATGCCATAGCGATTTACATCTATTAAGTGGTGAATTGGTAGGGCCACTTC
CTAACGGGTTTATAATTGGTCACGAAATAGCTGGGTGGGTAGAGAAGATAGGTGAGAACGTTAAGAATCCATATGGACTA
AAGGAGGGAGATCCAGTTCTAGTATCTTGGATAGTTCCATGTGGTATATGTAGATATTGCGCAAATGGTAAGGAGAATTA
TTGTAAAGATAATGCAAAGAGACTAGTAGGTCTAATTGGTATTAATGGAGGTCATGCTGAGTATTTAACTGTTCCAGAGA
TAGCAGTAATTCCTCTGGCCAAAAATCTTGATCCATACTATTCTTCTCCAATTGCATGTGCATATGGTACTGCTTATAAT
GCATTAAAGAGTGCGAACGCTACTTCAGGAAAGAGTGTTGTTATAGTGGGAGCTGGTGGTGTAGGTTCTGCTGCAATACA
ATTGGCTAACTCAATTGGATTAAATCCTATTGTTGCAGTCGACATAGATGAGAATAAGTTAAAGAGTGCTAAATTACTGG
GCGCAACTCATATTATTAACGCTAACGAAAATGATGCGAGGGCGAAAGTTCTGGAAGCTTTAGAAGATGGTGCTGATATA
GTATATGAGACAAAACCTTATCCAGATTTCAAATTATCGTTAGAAGTAGTTAAAAGCGGTGGGACTATAGTTGTTACGGG
ATTGGGAGGATTCTCTACATTAGCACAAATTCCCGTAACACTATTCGTCTCCAGAGGTATAACCTTAATAGGAAGTTTAG
GCTACAGACCTAGAATTGATTTACCCGATCTAGTAAGTTTGGCCTCTTCCGGGAAAATCGACATTAAGAAGTTAGTTTCG
CATATTTACACTCCAGACATGATAAATGAGGCTTATGAGAATTTAAAGAAAGGGTTACACATAAGGGCTATAATAAGATG
GAATTAG

Upstream 100 bases:

>100_bases
TATCTCTAGGGGAGTTTATATATAAATAGAGAGGTATTAAATAAAAAGTCGACTATTATAAAGGAAGAAATTAATTCTAT
TAAAGATATAGAAAGAAACA

Downstream 100 bases:

>100_bases
AAAGTTTTTTATTGCTAAAAATTTTATATTATTCATGTACTCCCTAAAGGATAAGGTCGTTGTAGTAACGGGTTCTGGTA
GGGGTATTGGTAGGGCAATA

Product: zinc-containing alcohol dehydrogenase

Products: NA

Alternate protein names: ADH [H]

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MKAAVYKGYGLPLEIEEVPNPAPKEGEVLVKVASTGICHSDLHLLSGELVGPLPNGFIIGHEIAGWVEKIGENVKNPYGL
KEGDPVLVSWIVPCGICRYCANGKENYCKDNAKRLVGLIGINGGHAEYLTVPEIAVIPLAKNLDPYYSSPIACAYGTAYN
ALKSANATSGKSVVIVGAGGVGSAAIQLANSIGLNPIVAVDIDENKLKSAKLLGATHIINANENDARAKVLEALEDGADI
VYETKPYPDFKLSLEVVKSGGTIVVTGLGGFSTLAQIPVTLFVSRGITLIGSLGYRPRIDLPDLVSLASSGKIDIKKLVS
HIYTPDMINEAYENLKKGLHIRAIIRWN

Sequences:

>Translated_348_residues
MKAAVYKGYGLPLEIEEVPNPAPKEGEVLVKVASTGICHSDLHLLSGELVGPLPNGFIIGHEIAGWVEKIGENVKNPYGL
KEGDPVLVSWIVPCGICRYCANGKENYCKDNAKRLVGLIGINGGHAEYLTVPEIAVIPLAKNLDPYYSSPIACAYGTAYN
ALKSANATSGKSVVIVGAGGVGSAAIQLANSIGLNPIVAVDIDENKLKSAKLLGATHIINANENDARAKVLEALEDGADI
VYETKPYPDFKLSLEVVKSGGTIVVTGLGGFSTLAQIPVTLFVSRGITLIGSLGYRPRIDLPDLVSLASSGKIDIKKLVS
HIYTPDMINEAYENLKKGLHIRAIIRWN
>Mature_348_residues
MKAAVYKGYGLPLEIEEVPNPAPKEGEVLVKVASTGICHSDLHLLSGELVGPLPNGFIIGHEIAGWVEKIGENVKNPYGL
KEGDPVLVSWIVPCGICRYCANGKENYCKDNAKRLVGLIGINGGHAEYLTVPEIAVIPLAKNLDPYYSSPIACAYGTAYN
ALKSANATSGKSVVIVGAGGVGSAAIQLANSIGLNPIVAVDIDENKLKSAKLLGATHIINANENDARAKVLEALEDGADI
VYETKPYPDFKLSLEVVKSGGTIVVTGLGGFSTLAQIPVTLFVSRGITLIGSLGYRPRIDLPDLVSLASSGKIDIKKLVS
HIYTPDMINEAYENLKKGLHIRAIIRWN

Specific function: Active with primary alcohols, including methanol [H]

COG id: COG1064

COG function: function code R; Zn-dependent alcohol dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501933, Length=373, Percent_Identity=32.4396782841823, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI34577061, Length=373, Percent_Identity=32.171581769437, Blast_Score=152, Evalue=3e-37,
Organism=Homo sapiens, GI4501929, Length=373, Percent_Identity=32.9758713136729, Blast_Score=152, Evalue=6e-37,
Organism=Homo sapiens, GI156523966, Length=371, Percent_Identity=31.5363881401617, Blast_Score=141, Evalue=8e-34,
Organism=Homo sapiens, GI71743840, Length=373, Percent_Identity=29.7587131367292, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI262073058, Length=373, Percent_Identity=29.7587131367292, Blast_Score=136, Evalue=2e-32,
Organism=Homo sapiens, GI4501939, Length=364, Percent_Identity=31.3186813186813, Blast_Score=136, Evalue=2e-32,
Organism=Homo sapiens, GI71565154, Length=374, Percent_Identity=31.5508021390374, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI71565152, Length=375, Percent_Identity=27.4666666666667, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI156627571, Length=350, Percent_Identity=26, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI194239674, Length=281, Percent_Identity=28.8256227758007, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI13236495, Length=281, Percent_Identity=28.8256227758007, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI22538446, Length=222, Percent_Identity=30.1801801801802, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI22538444, Length=222, Percent_Identity=30.1801801801802, Blast_Score=75, Evalue=6e-14,
Organism=Escherichia coli, GI1788073, Length=320, Percent_Identity=35.625, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1786552, Length=374, Percent_Identity=30.7486631016043, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1790045, Length=344, Percent_Identity=26.453488372093, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI87081918, Length=293, Percent_Identity=33.1058020477816, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI87082125, Length=339, Percent_Identity=29.2035398230088, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1790718, Length=314, Percent_Identity=28.0254777070064, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI226510992, Length=318, Percent_Identity=27.9874213836478, Blast_Score=101, Evalue=8e-23,
Organism=Escherichia coli, GI1786825, Length=258, Percent_Identity=31.3953488372093, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1788407, Length=352, Percent_Identity=26.7045454545455, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1786518, Length=340, Percent_Identity=28.8235294117647, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787863, Length=332, Percent_Identity=28.0120481927711, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI87082401, Length=340, Percent_Identity=27.0588235294118, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1788075, Length=347, Percent_Identity=24.7838616714697, Blast_Score=82, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17562876, Length=346, Percent_Identity=29.4797687861272, Blast_Score=138, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI25146526, Length=374, Percent_Identity=29.4117647058824, Blast_Score=135, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI71997431, Length=376, Percent_Identity=29.2553191489362, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI71988145, Length=321, Percent_Identity=32.0872274143302, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17562584, Length=317, Percent_Identity=32.807570977918, Blast_Score=117, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI17562582, Length=324, Percent_Identity=31.4814814814815, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17562878, Length=345, Percent_Identity=28.1159420289855, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17565904, Length=343, Percent_Identity=27.1137026239067, Blast_Score=109, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6320033, Length=381, Percent_Identity=28.0839895013123, Blast_Score=136, Evalue=6e-33,
Organism=Saccharomyces cerevisiae, GI6324486, Length=339, Percent_Identity=31.5634218289086, Blast_Score=121, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6323729, Length=260, Percent_Identity=33.8461538461538, Blast_Score=120, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6323099, Length=317, Percent_Identity=30.2839116719243, Blast_Score=116, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6323961, Length=343, Percent_Identity=31.1953352769679, Blast_Score=114, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6319621, Length=343, Percent_Identity=31.1953352769679, Blast_Score=112, Evalue=6e-26,
Organism=Saccharomyces cerevisiae, GI6322619, Length=332, Percent_Identity=27.1084337349398, Blast_Score=101, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6319955, Length=332, Percent_Identity=27.1084337349398, Blast_Score=100, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6319258, Length=364, Percent_Identity=26.0989010989011, Blast_Score=90, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6323980, Length=330, Percent_Identity=29.0909090909091, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6319949, Length=323, Percent_Identity=29.4117647058824, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6319257, Length=363, Percent_Identity=24.5179063360882, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17737895, Length=374, Percent_Identity=29.144385026738, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI17737897, Length=357, Percent_Identity=28.2913165266106, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI17137530, Length=361, Percent_Identity=27.1468144044321, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI45551930, Length=338, Percent_Identity=24.2603550295858, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI45550770, Length=338, Percent_Identity=24.2603550295858, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI221457811, Length=338, Percent_Identity=24.2603550295858, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 36921; Mature: 36921

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAAVYKGYGLPLEIEEVPNPAPKEGEVLVKVASTGICHSDLHLLSGELVGPLPNGFIIG
CCCEEEECCCCCEEHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHCCCEECCCCCCEEEH
HEIAGWVEKIGENVKNPYGLKEGDPVLVSWIVPCGICRYCANGKENYCKDNAKRLVGLIG
HHHHHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHCCCCHHHHHHHHHEEEEEEE
INGGHAEYLTVPEIAVIPLAKNLDPYYSSPIACAYGTAYNALKSANATSGKSVVIVGAGG
ECCCCEEEEECCCEEEEEECCCCCCCCCCCEEEEHHHHHHHHHCCCCCCCCEEEEEECCC
VGSAAIQLANSIGLNPIVAVDIDENKLKSAKLLGATHIINANENDARAKVLEALEDGADI
CCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHCCCCE
VYETKPYPDFKLSLEVVKSGGTIVVTGLGGFSTLAQIPVTLFVSRGITLIGSLGYRPRID
EEECCCCCCCEEEEEEEECCCEEEEECCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCCC
LPDLVSLASSGKIDIKKLVSHIYTPDMINEAYENLKKGLHIRAIIRWN
CHHHHHHHCCCCEEHHHHHHHHCCHHHHHHHHHHHHCCCEEEEEEEEC
>Mature Secondary Structure
MKAAVYKGYGLPLEIEEVPNPAPKEGEVLVKVASTGICHSDLHLLSGELVGPLPNGFIIG
CCCEEEECCCCCEEHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHCCCEECCCCCCEEEH
HEIAGWVEKIGENVKNPYGLKEGDPVLVSWIVPCGICRYCANGKENYCKDNAKRLVGLIG
HHHHHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHCCCCHHHHHHHHHEEEEEEE
INGGHAEYLTVPEIAVIPLAKNLDPYYSSPIACAYGTAYNALKSANATSGKSVVIVGAGG
ECCCCEEEEECCCEEEEEECCCCCCCCCCCEEEEHHHHHHHHHCCCCCCCCEEEEEECCC
VGSAAIQLANSIGLNPIVAVDIDENKLKSAKLLGATHIINANENDARAKVLEALEDGADI
CCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHCCCCE
VYETKPYPDFKLSLEVVKSGGTIVVTGLGGFSTLAQIPVTLFVSRGITLIGSLGYRPRID
EEECCCCCCCEEEEEEEECCCEEEEECCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCCC
LPDLVSLASSGKIDIKKLVSHIYTPDMINEAYENLKKGLHIRAIIRWN
CHHHHHHHCCCCEEHHHHHHHHCCHHHHHHHHHHHHCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8049268 [H]