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The map label for this gene is yqjC [H]

Identifier: 15899175

GI number: 15899175

Start: 2205318

End: 2205746

Strand: Direct

Name: yqjC [H]

Synonym: SSO2426

Alternate gene names: 15899175

Gene position: 2205318-2205746 (Clockwise)

Preceding gene: 15899173

Following gene: 15899176

Centisome position: 73.7

GC content: 34.73

Gene sequence:

>429_bases
ATGCAGATAGAAAATCTAGATCATATTGGGATAGTAGTTGGGAATCTAGACGAGGCAATTAAATTTTATCAAAATACTTT
TGGAATGAAATTAGTACATTACGAGTTAATTCCAGAGAGAGGTATAAAGGTAGCGTTTTTAGTTAGTAATGAAAAAAATG
AAACCTCAATAGAATTGTTAGAACCAATCGATCATAACGACATGAGTAACACTGTGGCCAAGTTTCTGAAAAATAGAGGC
CAAGGTTTACATCATTTGGCTATAAAAGTTAGTGATATTAATAGGGCGTTAGAAGAATTAACAGCTAAAGGCCTTCAATT
AGTAGATACTTCCCCAAGAAAGGGCGCAAGAGGACACCTAGTAGCTTTCTTACATCCCAAAAGCGTTATGGGAGTACTAC
TTGAATTGGTACAAGCAAAGGAATTATAA

Upstream 100 bases:

>100_bases
AATTCTATCTTCAACATCCATAATATGTTTAAATCTTATAAACACTATAAAACTTTTTCTTCAGGGCAAAACTTTTAAGA
TTAAACAATACGATCATTTA

Downstream 100 bases:

>100_bases
ATATCAAGATGCATTGGATAATGGATGTAAGAAACTTTAAAATTATATTTTCATTAATATATAACGATAGTCTATGCCCA
AGAGGGAAGAAAAGGATATT

Product: lactoylglutathione lyase (glyoxalase I), putative

Products: glutathione; methylglyoxal

Alternate protein names: NA

Number of amino acids: Translated: 142; Mature: 142

Protein sequence:

>142_residues
MQIENLDHIGIVVGNLDEAIKFYQNTFGMKLVHYELIPERGIKVAFLVSNEKNETSIELLEPIDHNDMSNTVAKFLKNRG
QGLHHLAIKVSDINRALEELTAKGLQLVDTSPRKGARGHLVAFLHPKSVMGVLLELVQAKEL

Sequences:

>Translated_142_residues
MQIENLDHIGIVVGNLDEAIKFYQNTFGMKLVHYELIPERGIKVAFLVSNEKNETSIELLEPIDHNDMSNTVAKFLKNRG
QGLHHLAIKVSDINRALEELTAKGLQLVDTSPRKGARGHLVAFLHPKSVMGVLLELVQAKEL
>Mature_142_residues
MQIENLDHIGIVVGNLDEAIKFYQNTFGMKLVHYELIPERGIKVAFLVSNEKNETSIELLEPIDHNDMSNTVAKFLKNRG
QGLHHLAIKVSDINRALEELTAKGLQLVDTSPRKGARGHLVAFLHPKSVMGVLLELVQAKEL

Specific function: Unknown

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyoxalase I family [H]

Homologues:

Organism=Homo sapiens, GI188035928, Length=135, Percent_Identity=39.2592592592593, Blast_Score=88, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17506387, Length=134, Percent_Identity=35.8208955223881, Blast_Score=79, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360
- InterPro:   IPR018146
- InterPro:   IPR017515 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: 4.4.1.5

Molecular weight: Translated: 15875; Mature: 15875

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIENLDHIGIVVGNLDEAIKFYQNTFGMKLVHYELIPERGIKVAFLVSNEKNETSIELL
CCCCCCCEEEEEECCHHHHHHHHHHHCCEEEEEEEECCCCCCEEEEEEECCCCCCCEEEE
EPIDHNDMSNTVAKFLKNRGQGLHHLAIKVSDINRALEELTAKGLQLVDTSPRKGARGHL
CCCCCCCHHHHHHHHHHHCCCCEEEEEEEEHHHHHHHHHHHHCCEEEEECCCCCCCCCCE
VAFLHPKSVMGVLLELVQAKEL
EEEECCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQIENLDHIGIVVGNLDEAIKFYQNTFGMKLVHYELIPERGIKVAFLVSNEKNETSIELL
CCCCCCCEEEEEECCHHHHHHHHHHHCCEEEEEEEECCCCCCEEEEEEECCCCCCCEEEE
EPIDHNDMSNTVAKFLKNRGQGLHHLAIKVSDINRALEELTAKGLQLVDTSPRKGARGHL
CCCCCCCHHHHHHHHHHHCCCCEEEEEEEEHHHHHHHHHHHHCCEEEEECCCCCCCCCCE
VAFLHPKSVMGVLLELVQAKEL
EEEECCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (R)-S-lactoylglutathione

Specific reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]