Click here to switch to the map view.

The map label for this gene is gpT-2 [H]

Identifier: 15899173

GI number: 15899173

Start: 2203048

End: 2203587

Strand: Direct

Name: gpT-2 [H]

Synonym: SSO2424

Alternate gene names: 15899173

Gene position: 2203048-2203587 (Clockwise)

Preceding gene: 15899172

Following gene: 15899175

Centisome position: 73.63

GC content: 35.0

Gene sequence:

>540_bases
ATGGTTGAATATCATATTCCTTCATGGGATGAAATAGAAGATGCGGTTTTTTCGATAGGCGAGGCTCTAGTTAAGAGTAA
TTATATTCCAGACGTTTTGATTGCAGTACTAACTGGTGGAATTATACCCGCTAAACTTCTTTCCGACTTGCTAGATTTGA
AAGTAATTAGGTACATAGATATAAAATTTTATCGTAGCGTTGGAAAAACTGAAAGTAAACCAGTCATTAGATCTGTATAT
ACTGATTCCTTAGAGGGGAAGAAAGTCCTAGTAGTTGATGATGTTGCAGATACTGGTGAAACCTTAGAGGCTGTTAGTAA
TGTTATAACCATGTTTAACCCAGCTAAAGTGATGACTGCGGCTTTATACTTAAAACCGTGGTCTAAGAGGATCCCGGATT
TTTATTATAAACAAATTGACAAGTGGATAATTTTCCCGTGGGATAAGTGGGATGTTGTTAGGGAAAATAGTAATGTTCCA
GTTGACAAAAAGGAGAGATTCTTAAACTTGTATAATCAATTATTAAAGATCAGAAAATAG

Upstream 100 bases:

>100_bases
TTCATATTCAATTTTAAGGATAAGGACGAGTATGATAAACTTAAAGGGCATCATGGGGGACTATTGCAAGAGGAATTTGA
GATACCTTTGGTGATCTTGA

Downstream 100 bases:

>100_bases
AAGGTTCTTTATACTCTCCCCAAATATCTCTTAAAACGCCACTGGTCTCCCCTACTGTTGCCCCTGCCCTTATGGCATCA
ATCATGTATGGGAATAAATT

Product: purine phosphoribosyltransferase (gpT-2)

Products: NA

Alternate protein names: Xanthine-guanine phosphoribosyltransferase; XGPRT [H]

Number of amino acids: Translated: 179; Mature: 179

Protein sequence:

>179_residues
MVEYHIPSWDEIEDAVFSIGEALVKSNYIPDVLIAVLTGGIIPAKLLSDLLDLKVIRYIDIKFYRSVGKTESKPVIRSVY
TDSLEGKKVLVVDDVADTGETLEAVSNVITMFNPAKVMTAALYLKPWSKRIPDFYYKQIDKWIIFPWDKWDVVRENSNVP
VDKKERFLNLYNQLLKIRK

Sequences:

>Translated_179_residues
MVEYHIPSWDEIEDAVFSIGEALVKSNYIPDVLIAVLTGGIIPAKLLSDLLDLKVIRYIDIKFYRSVGKTESKPVIRSVY
TDSLEGKKVLVVDDVADTGETLEAVSNVITMFNPAKVMTAALYLKPWSKRIPDFYYKQIDKWIIFPWDKWDVVRENSNVP
VDKKERFLNLYNQLLKIRK
>Mature_179_residues
MVEYHIPSWDEIEDAVFSIGEALVKSNYIPDVLIAVLTGGIIPAKLLSDLLDLKVIRYIDIKFYRSVGKTESKPVIRSVY
TDSLEGKKVLVVDDVADTGETLEAVSNVITMFNPAKVMTAALYLKPWSKRIPDFYYKQIDKWIIFPWDKWDVVRENSNVP
VDKKERFLNLYNQLLKIRK

Specific function: Acts on guanine, xanthine and to a lesser extent hypoxanthine [H]

COG id: COG2236

COG function: function code R; Predicted phosphoribosyltransferases

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6322593, Length=187, Percent_Identity=30.4812834224599, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.22 [H]

Molecular weight: Translated: 20656; Mature: 20656

Theoretical pI: Translated: 7.49; Mature: 7.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEYHIPSWDEIEDAVFSIGEALVKSNYIPDVLIAVLTGGIIPAKLLSDLLDLKVIRYID
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
IKFYRSVGKTESKPVIRSVYTDSLEGKKVLVVDDVADTGETLEAVSNVITMFNPAKVMTA
HHHHHHHCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHH
ALYLKPWSKRIPDFYYKQIDKWIIFPWDKWDVVRENSNVPVDKKERFLNLYNQLLKIRK
HHHHCCHHHHCCHHHHHHHCCEEECCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVEYHIPSWDEIEDAVFSIGEALVKSNYIPDVLIAVLTGGIIPAKLLSDLLDLKVIRYID
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
IKFYRSVGKTESKPVIRSVYTDSLEGKKVLVVDDVADTGETLEAVSNVITMFNPAKVMTA
HHHHHHHCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHH
ALYLKPWSKRIPDFYYKQIDKWIIFPWDKWDVVRENSNVPVDKKERFLNLYNQLLKIRK
HHHHCCHHHHCCHHHHHHHCCEEECCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA