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The map label for this gene is fabG-5 [H]

Identifier: 15899043

GI number: 15899043

Start: 2084832

End: 2085617

Strand: Direct

Name: fabG-5 [H]

Synonym: SSO2276

Alternate gene names: 15899043

Gene position: 2084832-2085617 (Clockwise)

Preceding gene: 15899042

Following gene: 15899044

Centisome position: 69.67

GC content: 38.93

Gene sequence:

>786_bases
ATGGATCTGGGGATAAAGGGGAAAAAGGTAATAGTAACAGCGGCAAGTAAAGGTATAGGTTTGGCCATAGCTAAGCGTTT
TTTAGAGGAGGGTGCTAAAGTCATCATTTCATCTAATGACGAATCAAACTTAATGAAAGCATACAATAAACTAAAGGAGA
TTCATAGTGAAAATGTAAGTTACATAAAAGCAGATTTGATGAATCCACACGAAGTTAAGTCTCTAGTTCATGAGGGCTAT
AGAAAACTTGGAGGTTTAGATGTTTTAGCTTACGTTACTGGTAGTCCAAAACCTGGAAATTTATTTTCCTTATCAGATAA
GGACTGGATGGATGCGTTCAATCTACTCTTGTTAAGTGCAGTTGTTGCAGTTAGAGAAGCTGGTCAGCTAATGCAAAGTG
GTGGTAGGATAATACTATCCACGTCAACCACATTAAGGCAACCTATAGATAACCTCGATTTGTCAAATGTTGTAAGGCTT
TCATTAGCAGGGCTAATAAAGGTTGCGTCGAGGGAACTAGGACCTAAGGGTATTTTAGTAAATGGAGTAATGCCTGGTTG
GACAAAGACAGAAAGATTGCTTCAGATTATAAGGGATAGAGCAATAAGGGAGGGTAAGAGTGAAGATGAAGTTCTTAAGT
CAATTGTCGCGGATGTGCCTCTAGGTAGAGCAGGGGAGCCTGAAGAAATTGCTAATGTTGTATTATTTTTAGCGTCAAAT
CTTTCTACTTATGTTACCGGTGCCCTAATACCGGTAGATGGTGGGAGTATAAAAGGAGTCTTTTAA

Upstream 100 bases:

>100_bases
GCTCTTTATAATCCCCCTATTAGAAAAGTACTAGAAGAAGACTTCAGAAAAGTTAAAGAAGCATTAAGTTCAAAACCTAT
TACTCTGGATAATTTCTTGT

Downstream 100 bases:

>100_bases
GTGTTTTTGCAGATAATACTCCGTTTTTTCTCTATTTATAGACTAACGTGGAAAAAAGCTTGCTAACGATTATATTTTAT
TCTGCTAAGTATTACCGTAG

Product: 3-oxoacyl-(acyl carrier protein) reductase (fabG-5)

Products: 3-oxoacyl-[acyl-carrier protein]; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MDLGIKGKKVIVTAASKGIGLAIAKRFLEEGAKVIISSNDESNLMKAYNKLKEIHSENVSYIKADLMNPHEVKSLVHEGY
RKLGGLDVLAYVTGSPKPGNLFSLSDKDWMDAFNLLLLSAVVAVREAGQLMQSGGRIILSTSTTLRQPIDNLDLSNVVRL
SLAGLIKVASRELGPKGILVNGVMPGWTKTERLLQIIRDRAIREGKSEDEVLKSIVADVPLGRAGEPEEIANVVLFLASN
LSTYVTGALIPVDGGSIKGVF

Sequences:

>Translated_261_residues
MDLGIKGKKVIVTAASKGIGLAIAKRFLEEGAKVIISSNDESNLMKAYNKLKEIHSENVSYIKADLMNPHEVKSLVHEGY
RKLGGLDVLAYVTGSPKPGNLFSLSDKDWMDAFNLLLLSAVVAVREAGQLMQSGGRIILSTSTTLRQPIDNLDLSNVVRL
SLAGLIKVASRELGPKGILVNGVMPGWTKTERLLQIIRDRAIREGKSEDEVLKSIVADVPLGRAGEPEEIANVVLFLASN
LSTYVTGALIPVDGGSIKGVF
>Mature_261_residues
MDLGIKGKKVIVTAASKGIGLAIAKRFLEEGAKVIISSNDESNLMKAYNKLKEIHSENVSYIKADLMNPHEVKSLVHEGY
RKLGGLDVLAYVTGSPKPGNLFSLSDKDWMDAFNLLLLSAVVAVREAGQLMQSGGRIILSTSTTLRQPIDNLDLSNVVRL
SLAGLIKVASRELGPKGILVNGVMPGWTKTERLLQIIRDRAIREGKSEDEVLKSIVADVPLGRAGEPEEIANVVLFLASN
LSTYVTGALIPVDGGSIKGVF

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=258, Percent_Identity=29.0697674418605, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI5031737, Length=250, Percent_Identity=30, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI15277342, Length=255, Percent_Identity=26.6666666666667, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI33667109, Length=188, Percent_Identity=31.9148936170213, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI126723750, Length=263, Percent_Identity=27.7566539923954, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI10190704, Length=258, Percent_Identity=25.1937984496124, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI66933014, Length=254, Percent_Identity=30.3149606299213, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI40254992, Length=250, Percent_Identity=26.4, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI19923817, Length=260, Percent_Identity=25.7692307692308, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI38424085, Length=171, Percent_Identity=25.7309941520468, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI38348362, Length=171, Percent_Identity=25.7309941520468, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1789378, Length=258, Percent_Identity=29.8449612403101, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787905, Length=265, Percent_Identity=27.1698113207547, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1787335, Length=258, Percent_Identity=30.6201550387597, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1786812, Length=261, Percent_Identity=29.8850574712644, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI2367365, Length=251, Percent_Identity=29.8804780876494, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI87082100, Length=255, Percent_Identity=26.6666666666667, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI87082160, Length=260, Percent_Identity=26.5384615384615, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI1790717, Length=262, Percent_Identity=24.0458015267176, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1789208, Length=263, Percent_Identity=24.3346007604563, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1788459, Length=249, Percent_Identity=27.3092369477912, Blast_Score=77, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17561402, Length=261, Percent_Identity=32.183908045977, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI25147288, Length=263, Percent_Identity=29.6577946768061, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17555706, Length=259, Percent_Identity=31.6602316602317, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17560676, Length=248, Percent_Identity=27.8225806451613, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17560220, Length=268, Percent_Identity=29.1044776119403, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562910, Length=264, Percent_Identity=29.1666666666667, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17562904, Length=260, Percent_Identity=27.6923076923077, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17560150, Length=269, Percent_Identity=26.3940520446097, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI72000259, Length=259, Percent_Identity=27.4131274131274, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193204405, Length=268, Percent_Identity=27.9850746268657, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17544670, Length=268, Percent_Identity=25.7462686567164, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=264, Percent_Identity=27.6515151515151, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI115534694, Length=254, Percent_Identity=27.9527559055118, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17560332, Length=259, Percent_Identity=27.027027027027, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=267, Percent_Identity=26.5917602996255, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71994604, Length=253, Percent_Identity=24.901185770751, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562906, Length=263, Percent_Identity=26.615969581749, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17559104, Length=259, Percent_Identity=25.0965250965251, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17538486, Length=266, Percent_Identity=28.1954887218045, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17538480, Length=266, Percent_Identity=26.3157894736842, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI21355319, Length=254, Percent_Identity=33.0708661417323, Blast_Score=123, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24639444, Length=264, Percent_Identity=29.9242424242424, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI23397609, Length=259, Percent_Identity=29.7297297297297, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24644339, Length=254, Percent_Identity=25.1968503937008, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI28571526, Length=256, Percent_Identity=26.5625, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24644337, Length=255, Percent_Identity=28.6274509803922, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21357041, Length=256, Percent_Identity=26.171875, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100

Molecular weight: Translated: 28060; Mature: 28060

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLGIKGKKVIVTAASKGIGLAIAKRFLEEGAKVIISSNDESNLMKAYNKLKEIHSENVS
CCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHCCHH
YIKADLMNPHEVKSLVHEGYRKLGGLDVLAYVTGSPKPGNLFSLSDKDWMDAFNLLLLSA
HHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCEEECCCHHHHHHHHHHHHHH
VVAVREAGQLMQSGGRIILSTSTTLRQPIDNLDLSNVVRLSLAGLIKVASRELGPKGILV
HHHHHHHHHHHHCCCEEEEECCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEE
NGVMPGWTKTERLLQIIRDRAIREGKSEDEVLKSIVADVPLGRAGEPEEIANVVLFLASN
ECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHC
LSTYVTGALIPVDGGSIKGVF
HHHHHHEEEEECCCCCCCCCC
>Mature Secondary Structure
MDLGIKGKKVIVTAASKGIGLAIAKRFLEEGAKVIISSNDESNLMKAYNKLKEIHSENVS
CCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHCCHH
YIKADLMNPHEVKSLVHEGYRKLGGLDVLAYVTGSPKPGNLFSLSDKDWMDAFNLLLLSA
HHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCEEECCCHHHHHHHHHHHHHH
VVAVREAGQLMQSGGRIILSTSTTLRQPIDNLDLSNVVRLSLAGLIKVASRELGPKGILV
HHHHHHHHHHHHCCCEEEEECCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEE
NGVMPGWTKTERLLQIIRDRAIREGKSEDEVLKSIVADVPLGRAGEPEEIANVVLFLASN
ECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHC
LSTYVTGALIPVDGGSIKGVF
HHHHHHEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (3R)-3-hydroxyacyl-[acyl-carrier protein]; NADP+

Specific reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]