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The map label for this gene is dapA-1 [H]

Identifier: 15899041

GI number: 15899041

Start: 2083299

End: 2084168

Strand: Direct

Name: dapA-1 [H]

Synonym: SSO2274

Alternate gene names: 15899041

Gene position: 2083299-2084168 (Clockwise)

Preceding gene: 15899039

Following gene: 15899042

Centisome position: 69.62

GC content: 32.87

Gene sequence:

>870_bases
GTGAAAGAGAATATTTCCGCTCTTGTTACACCCTATGACGATAAGGAAAATATAAATACTGAAGCGTTACAACAGCTATT
GGACTTTTTAATTAAAAAAGGAATTAAGGACTTTTGGGTTCTTGGCACTAGTGGAGAGTTTAATATGCTTTCTCAAGATG
AGAGAATATTAGTAGTTAGTAAAATACGTGAGATGGTTAAAGGTAAAATATATGTAGGTGTCAATGAGAACTCAACCAGA
AATAGTCTAATATTAGCTAAAAAATACTATGATCTAGGTGTTGATTATATTTTTTCAGTTCCACCTATTTATCATAAACC
TTCAGAAAAAGGACTAATATCGTATTTTAGCGAGTTGCGTAATGCTATAGATTTACCATTATTCATATATAATATACCCT
CCTTTACAGGATATAATGTTCCTCTTCATATAATTGAGAAGCTAGCGAGAGAGTACGTATTAGATGGTATGAAGTACTCA
ACTACAGATTTTGTCTCTTTTCTAAAGTATTTAAAGGCACTAAAAGGAGTAAATAAGAACTTCAAAGTATTCATTGGCGA
GGATAGGATGATCCTTTCCGCTCTTATTTTAGATACTGATGGTGCAGTTTCTGGTATTTCCAATTTAGTTCCTGAATTAG
TCACCAATTTATTCTTGGAATTTGATAGAGGTAACATTCAGAGGGCTATAGAGATTCAGAGAATTTTGAACAAATTGGTA
GACGTGGTAAGTTTAGGCGATTATCCCAGTGGTATTAAGATAGGTTTAAGGTATAGGGGAATTAATGTCGGTAGTGTTAG
GAAACCTTTATTAGAGGATAGTAGAGCCGAAGGTGAAATATATAATGTACTGAAAGAATTAGGTATATAG

Upstream 100 bases:

>100_bases
TATGGTAAGCAGATATGAGAATTCTCTTCGTGATAAGTTAGACATCTGTGAATCAACTCTCAATAAAAATAAATAAAGTT
TTGTTCTAAAACATACAATC

Downstream 100 bases:

>100_bases
GAATGATGAAGGTCGATGGGAATTACTGGATAATGAGGAAAATTATCCCCGGCTGAGGAATTATGGATAACTTGGATCTT
ATTGCAGATGAGGTAAGAAA

Product: dihydrodipicolinate synthase (dapA-1)

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MKENISALVTPYDDKENINTEALQQLLDFLIKKGIKDFWVLGTSGEFNMLSQDERILVVSKIREMVKGKIYVGVNENSTR
NSLILAKKYYDLGVDYIFSVPPIYHKPSEKGLISYFSELRNAIDLPLFIYNIPSFTGYNVPLHIIEKLAREYVLDGMKYS
TTDFVSFLKYLKALKGVNKNFKVFIGEDRMILSALILDTDGAVSGISNLVPELVTNLFLEFDRGNIQRAIEIQRILNKLV
DVVSLGDYPSGIKIGLRYRGINVGSVRKPLLEDSRAEGEIYNVLKELGI

Sequences:

>Translated_289_residues
MKENISALVTPYDDKENINTEALQQLLDFLIKKGIKDFWVLGTSGEFNMLSQDERILVVSKIREMVKGKIYVGVNENSTR
NSLILAKKYYDLGVDYIFSVPPIYHKPSEKGLISYFSELRNAIDLPLFIYNIPSFTGYNVPLHIIEKLAREYVLDGMKYS
TTDFVSFLKYLKALKGVNKNFKVFIGEDRMILSALILDTDGAVSGISNLVPELVTNLFLEFDRGNIQRAIEIQRILNKLV
DVVSLGDYPSGIKIGLRYRGINVGSVRKPLLEDSRAEGEIYNVLKELGI
>Mature_289_residues
MKENISALVTPYDDKENINTEALQQLLDFLIKKGIKDFWVLGTSGEFNMLSQDERILVVSKIREMVKGKIYVGVNENSTR
NSLILAKKYYDLGVDYIFSVPPIYHKPSEKGLISYFSELRNAIDLPLFIYNIPSFTGYNVPLHIIEKLAREYVLDGMKYS
TTDFVSFLKYLKALKGVNKNFKVFIGEDRMILSALILDTDGAVSGISNLVPELVTNLFLEFDRGNIQRAIEIQRILNKLV
DVVSLGDYPSGIKIGLRYRGINVGSVRKPLLEDSRAEGEIYNVLKELGI

Specific function: Unknown

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI13540533, Length=286, Percent_Identity=29.3706293706294, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI31543060, Length=277, Percent_Identity=25.9927797833935, Blast_Score=89, Evalue=5e-18,
Organism=Escherichia coli, GI87082415, Length=280, Percent_Identity=28.5714285714286, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1788823, Length=291, Percent_Identity=27.1477663230241, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1786463, Length=250, Percent_Identity=28.4, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1789620, Length=272, Percent_Identity=27.2058823529412, Blast_Score=101, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 32746; Mature: 32746

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: PS00666 DHDPS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKENISALVTPYDDKENINTEALQQLLDFLIKKGIKDFWVLGTSGEFNMLSQDERILVVS
CCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCEEHHH
KIREMVKGKIYVGVNENSTRNSLILAKKYYDLGVDYIFSVPPIYHKPSEKGLISYFSELR
HHHHHHCCEEEEEECCCCCCCEEEEEHHHHHCCCHHEECCCCCCCCCCCCHHHHHHHHHH
NAIDLPLFIYNIPSFTGYNVPLHIIEKLAREYVLDGMKYSTTDFVSFLKYLKALKGVNKN
HHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCC
FKVFIGEDRMILSALILDTDGAVSGISNLVPELVTNLFLEFDRGNIQRAIEIQRILNKLV
CEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
DVVSLGDYPSGIKIGLRYRGINVGSVRKPLLEDSRAEGEIYNVLKELGI
HHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MKENISALVTPYDDKENINTEALQQLLDFLIKKGIKDFWVLGTSGEFNMLSQDERILVVS
CCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCEEHHH
KIREMVKGKIYVGVNENSTRNSLILAKKYYDLGVDYIFSVPPIYHKPSEKGLISYFSELR
HHHHHHCCEEEEEECCCCCCCEEEEEHHHHHCCCHHEECCCCCCCCCCCCHHHHHHHHHH
NAIDLPLFIYNIPSFTGYNVPLHIIEKLAREYVLDGMKYSTTDFVSFLKYLKALKGVNKN
HHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCC
FKVFIGEDRMILSALILDTDGAVSGISNLVPELVTNLFLEFDRGNIQRAIEIQRILNKLV
CEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
DVVSLGDYPSGIKIGLRYRGINVGSVRKPLLEDSRAEGEIYNVLKELGI
HHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA