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The map label for this gene is iunH-2 [C]

Identifier: 15899016

GI number: 15899016

Start: 2058349

End: 2059272

Strand: Direct

Name: iunH-2 [C]

Synonym: SSO2243

Alternate gene names: 15899016

Gene position: 2058349-2059272 (Clockwise)

Preceding gene: 15899015

Following gene: 15899018

Centisome position: 68.79

GC content: 35.39

Gene sequence:

>924_bases
ATGAGGAAAGTTATAGTGGATTCAGATACTGCCACTGATGATACTATAGCGATATTACTTGCATCCAGATTTTTTCAATT
ATTAGGTGTAACCATAGTTGCTGGAAATGTAAATTATAATCAAGAGGTTAAGAATGCCCTTTTTACTTTAGAGTATATTG
GTAAGCAGGATGTACCAGTTTATTTAGGCTCACAAAGACCTATCTTAGGAAATTGGAGAACTGTTGAAGAGGTTCATGGA
AGTAATGGAATGAGTAATTGGAACTACCCTGAACCTAATAAAAGGCCAGAGAAAGAGCATGCTATAGATGCCATACTCAG
ATTATCAAAAGAACATGAAGGTGAGTTGGAAATACTTGCAATTTCCCCTTTAACAAATATTGCATTAGCCTATCTTAAGG
ATCCATCAGTTGTTAAACGAGTGAAAAAGATTTGGATAATGGGTGGTGCATTTTCAAAGGGTAACACTACCCCCATAGCA
GAGTTCAATTTTTGGGTAGATCCTGAGGCTGCTAAAATAGTTTTAGATGCAGGATTTGACATCACCATAGTTCCTTGGGA
AGTTGCCGAAATAAGTGGTTCTTTGAATGAGAGAGACTGGGAATATATCTCTAAGCTTAATACTAAGCTTTCAAACTTTT
TTATTAACGTTAATAAGACGCTAAAGGAATATACCACTAAGAATCAAGGCATATCTGGCAGTATCCATCCAGATTCCTTA
ACAGTTTCGATAGCTCATGACAACTCTATTATCTTAGATTCTTCTCTAAAGTATGTTGATGTTGAATTATGTTCAAAATC
TAGAGGAGCAATGTTAATAGACTGGTACAGTTTACATAAAAACAAGCCTAATGCTGAAATTGTACTAAAGGCAGATGGTG
GTAAGTTTAAAAATCTTCTATTCAACTCTCTTTCCCAGCTTTGA

Upstream 100 bases:

>100_bases
TAAATTTGATCTGCTACCCAAATTTTCATGATTTATTAAAGTGCCAGAGGCAACTTTAGATACTTACTGTATAATTATAT
TGTCAAGGTGACATAGCTTT

Downstream 100 bases:

>100_bases
GCAATCAGCATATACTATAATATTAACGTTTTTTATATCTAAGCCATTTTTGGTTAGATTTTCCATAAAGTTATCCATTT
CAATATCTAGATCAATTATT

Product: purine nucleosidase, putative (iunH-2)

Products: D-ribose; purine

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MRKVIVDSDTATDDTIAILLASRFFQLLGVTIVAGNVNYNQEVKNALFTLEYIGKQDVPVYLGSQRPILGNWRTVEEVHG
SNGMSNWNYPEPNKRPEKEHAIDAILRLSKEHEGELEILAISPLTNIALAYLKDPSVVKRVKKIWIMGGAFSKGNTTPIA
EFNFWVDPEAAKIVLDAGFDITIVPWEVAEISGSLNERDWEYISKLNTKLSNFFINVNKTLKEYTTKNQGISGSIHPDSL
TVSIAHDNSIILDSSLKYVDVELCSKSRGAMLIDWYSLHKNKPNAEIVLKADGGKFKNLLFNSLSQL

Sequences:

>Translated_307_residues
MRKVIVDSDTATDDTIAILLASRFFQLLGVTIVAGNVNYNQEVKNALFTLEYIGKQDVPVYLGSQRPILGNWRTVEEVHG
SNGMSNWNYPEPNKRPEKEHAIDAILRLSKEHEGELEILAISPLTNIALAYLKDPSVVKRVKKIWIMGGAFSKGNTTPIA
EFNFWVDPEAAKIVLDAGFDITIVPWEVAEISGSLNERDWEYISKLNTKLSNFFINVNKTLKEYTTKNQGISGSIHPDSL
TVSIAHDNSIILDSSLKYVDVELCSKSRGAMLIDWYSLHKNKPNAEIVLKADGGKFKNLLFNSLSQL
>Mature_307_residues
MRKVIVDSDTATDDTIAILLASRFFQLLGVTIVAGNVNYNQEVKNALFTLEYIGKQDVPVYLGSQRPILGNWRTVEEVHG
SNGMSNWNYPEPNKRPEKEHAIDAILRLSKEHEGELEILAISPLTNIALAYLKDPSVVKRVKKIWIMGGAFSKGNTTPIA
EFNFWVDPEAAKIVLDAGFDITIVPWEVAEISGSLNERDWEYISKLNTKLSNFFINVNKTLKEYTTKNQGISGSIHPDSL
TVSIAHDNSIILDSSLKYVDVELCSKSRGAMLIDWYSLHKNKPNAEIVLKADGGKFKNLLFNSLSQL

Specific function: Unknown

COG id: COG1957

COG function: function code F; Inosine-uridine nucleoside N-ribohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IUNH family [H]

Homologues:

Organism=Escherichia coli, GI1786871, Length=305, Percent_Identity=29.8360655737705, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI1788486, Length=185, Percent_Identity=34.5945945945946, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1786213, Length=159, Percent_Identity=35.2201257861635, Blast_Score=102, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI32565474, Length=294, Percent_Identity=35.0340136054422, Blast_Score=146, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17565698, Length=290, Percent_Identity=30.6896551724138, Blast_Score=99, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6320608, Length=239, Percent_Identity=31.3807531380753, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24641839, Length=328, Percent_Identity=31.0975609756098, Blast_Score=129, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24583915, Length=328, Percent_Identity=28.0487804878049, Blast_Score=117, Evalue=7e-27,
Organism=Drosophila melanogaster, GI24641837, Length=240, Percent_Identity=30.4166666666667, Blast_Score=91, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015910
- InterPro:   IPR023186
- InterPro:   IPR001910 [H]

Pfam domain/function: PF01156 IU_nuc_hydro [H]

EC number: 3.2.2.1

Molecular weight: Translated: 34326; Mature: 34326

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS01247 IUNH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKVIVDSDTATDDTIAILLASRFFQLLGVTIVAGNVNYNQEVKNALFTLEYIGKQDVPV
CCEEEECCCCCCCHHHHHHHHHHHHHHHCEEEEECCCCCCHHHHHHHEEHHHCCCCCCCE
YLGSQRPILGNWRTVEEVHGSNGMSNWNYPEPNKRPEKEHAIDAILRLSKEHEGELEILA
EECCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEE
ISPLTNIALAYLKDPSVVKRVKKIWIMGGAFSKGNTTPIAEFNFWVDPEAAKIVLDAGFD
ECCHHHHHHHHCCCCHHHHHHHHHEEECCCCCCCCCCCEEEEEEEECCCCEEEEEECCCC
ITIVPWEVAEISGSLNERDWEYISKLNTKLSNFFINVNKTLKEYTTKNQGISGSIHPDSL
EEEECEEHEECCCCCCCHHHHHHHHHHHHHHHEEEEECHHHHHHHHCCCCCCCCCCCCEE
TVSIAHDNSIILDSSLKYVDVELCSKSRGAMLIDWYSLHKNKPNAEIVLKADGGKFKNLL
EEEEECCCEEEEECCCCEEEEEECCCCCCEEEEEEEEHHCCCCCCEEEEEECCCHHHHHH
FNSLSQL
HHHHHCC
>Mature Secondary Structure
MRKVIVDSDTATDDTIAILLASRFFQLLGVTIVAGNVNYNQEVKNALFTLEYIGKQDVPV
CCEEEECCCCCCCHHHHHHHHHHHHHHHCEEEEECCCCCCHHHHHHHEEHHHCCCCCCCE
YLGSQRPILGNWRTVEEVHGSNGMSNWNYPEPNKRPEKEHAIDAILRLSKEHEGELEILA
EECCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEE
ISPLTNIALAYLKDPSVVKRVKKIWIMGGAFSKGNTTPIAEFNFWVDPEAAKIVLDAGFD
ECCHHHHHHHHCCCCHHHHHHHHHEEECCCCCCCCCCCEEEEEEEECCCCEEEEEECCCC
ITIVPWEVAEISGSLNERDWEYISKLNTKLSNFFINVNKTLKEYTTKNQGISGSIHPDSL
EEEECEEHEECCCCCCCHHHHHHHHHHHHHHHEEEEECHHHHHHHHCCCCCCCCCCCCEE
TVSIAHDNSIILDSSLKYVDVELCSKSRGAMLIDWYSLHKNKPNAEIVLKADGGKFKNLL
EEEEECCCEEEEECCCCEEEEEECCCCCCEEEEEEEEHHCCCCCCEEEEEECCCHHHHHH
FNSLSQL
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-D-ribosylpurine; H2O

Specific reaction: an N-D-ribosylpurine + H2O = D-ribose + a purine

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA