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The map label for this gene is trxB-1 [C]

Identifier: 15898996

GI number: 15898996

Start: 2043206

End: 2044204

Strand: Direct

Name: trxB-1 [C]

Synonym: SSO2222

Alternate gene names: 15898996

Gene position: 2043206-2044204 (Clockwise)

Preceding gene: 15898994

Following gene: 15898997

Centisome position: 68.28

GC content: 38.24

Gene sequence:

>999_bases
GTGGATGAATACGATATAGTTGTAATTGGAGGTGGCCCAGTAGGTCTATTCGGTACTTTTTATGCAGGATTAAGAGATAT
GAAAACATTATTGATAGATGCTCAAGATGAGCTAGGCGGTCAACTAGTATCATTATATCCAGAGAAAATTGTATATGATG
TAGGTGGTTTGGCAGGAATCCAAGCTTATGAATTAGCTCAAAGGCTTATTGAGCAAGCTAAAATGTTTGGCCCAGATATA
AAAGTTAATGAATTAGCTGACATGATAGAGAAAACTAACGATAACATGTGGATAGTTAAGACTGATAAAGCCACATACAA
AACTAAGACTATTTTCATTGCAGCAGGTATAGGGAAGATAGTTCCTTCAAGGTTAGGGGCTAAAGGAGAGATCGAGTACG
AGAATAGAGGGGTCTATTATACCGTAAGAAGGAAGAAAGACTTTGAGGGTAAGAGGGTATTAATAGTAGGTGGTGGAGAT
TCAGCAGTAGATTGGGCATTAACTTTAGCTCCAGTAGCTAAATCTGTGACATTAATACATAGAAGAGATCAATTTAGAGC
TCATGAGAGAAGTGTAAAGGAGCTCTTTAGGGTAGCTAACGTTTATGTTTGGCATGAATTAAAAGAAGTTAAAGGGGATG
GTAATAAGGTAACCCAAGCAATAATATTCGATAATAGGACAAAGGAGGAGAAAGTGTTAGATGTAGATAGTGTAATTATA
AGTATAGGATACAAAGGTGATCTTGGTAATATTCCTAAATGGGGAGTAACCATGAAAGGTAGGGATATAGTCGTTAACGG
TAGGATGGAAACTAACTTACCTGGTGTTTATGCTGGAGGGGATATTGTACAGATGGAAGGTTCTCCCAAGTTAGCGCTAA
TAGCTGTAGGTTTTGCTCATGCTGCCATCGCTATAAGTGTAGCCAAGAAGTATGTGGAGCCTAATGCATCCTTATTTGCC
GGCCACAGTTCGGAAATGGACAAATTTAAACCTAAGTAA

Upstream 100 bases:

>100_bases
GTGTAATCAGTCATATATATATCTTTACGTTATTTGGTAATAAAAATTTGCACTAAGGTTTAAATAGTATAAATACTACA
ACCTAATAGGTGGTGTATAA

Downstream 100 bases:

>100_bases
TCATTCTTTTTCTCTAAATACAATGAAGACTAAAAGGCTTAGTGAGTTTTTCCCTGGTGTAAGAAGTTATTATATCGTAG
GCGAGATAGCCATAATAACT

Product: thioredoxin reductase (trxB-1)

Products: NA

Alternate protein names: FNR; Fd-NADP+ reductase

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MDEYDIVVIGGGPVGLFGTFYAGLRDMKTLLIDAQDELGGQLVSLYPEKIVYDVGGLAGIQAYELAQRLIEQAKMFGPDI
KVNELADMIEKTNDNMWIVKTDKATYKTKTIFIAAGIGKIVPSRLGAKGEIEYENRGVYYTVRRKKDFEGKRVLIVGGGD
SAVDWALTLAPVAKSVTLIHRRDQFRAHERSVKELFRVANVYVWHELKEVKGDGNKVTQAIIFDNRTKEEKVLDVDSVII
SIGYKGDLGNIPKWGVTMKGRDIVVNGRMETNLPGVYAGGDIVQMEGSPKLALIAVGFAHAAIAISVAKKYVEPNASLFA
GHSSEMDKFKPK

Sequences:

>Translated_332_residues
MDEYDIVVIGGGPVGLFGTFYAGLRDMKTLLIDAQDELGGQLVSLYPEKIVYDVGGLAGIQAYELAQRLIEQAKMFGPDI
KVNELADMIEKTNDNMWIVKTDKATYKTKTIFIAAGIGKIVPSRLGAKGEIEYENRGVYYTVRRKKDFEGKRVLIVGGGD
SAVDWALTLAPVAKSVTLIHRRDQFRAHERSVKELFRVANVYVWHELKEVKGDGNKVTQAIIFDNRTKEEKVLDVDSVII
SIGYKGDLGNIPKWGVTMKGRDIVVNGRMETNLPGVYAGGDIVQMEGSPKLALIAVGFAHAAIAISVAKKYVEPNASLFA
GHSSEMDKFKPK
>Mature_332_residues
MDEYDIVVIGGGPVGLFGTFYAGLRDMKTLLIDAQDELGGQLVSLYPEKIVYDVGGLAGIQAYELAQRLIEQAKMFGPDI
KVNELADMIEKTNDNMWIVKTDKATYKTKTIFIAAGIGKIVPSRLGAKGEIEYENRGVYYTVRRKKDFEGKRVLIVGGGD
SAVDWALTLAPVAKSVTLIHRRDQFRAHERSVKELFRVANVYVWHELKEVKGDGNKVTQAIIFDNRTKEEKVLDVDSVII
SIGYKGDLGNIPKWGVTMKGRDIVVNGRMETNLPGVYAGGDIVQMEGSPKLALIAVGFAHAAIAISVAKKYVEPNASLFA
GHSSEMDKFKPK

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ferredoxin--NADP reductase type 2 family

Homologues:

Organism=Escherichia coli, GI1787114, Length=292, Percent_Identity=28.7671232876712, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87081763, Length=189, Percent_Identity=29.6296296296296, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6321898, Length=300, Percent_Identity=25.3333333333333, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6320560, Length=296, Percent_Identity=24.3243243243243, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): FENR_SULSO (Q97WJ5)

Other databases:

- EMBL:   AJ243598
- EMBL:   AE006641
- PIR:   H90391
- RefSeq:   NP_343601.1
- HSSP:   P52214
- ProteinModelPortal:   Q97WJ5
- GeneID:   1453718
- GenomeReviews:   AE006641_GR
- KEGG:   sso:SSO2222
- NMPDR:   fig|273057.1.peg.2024
- HOGENOM:   HBG669726
- OMA:   FQVFELG
- ProtClustDB:   CLSK803258
- BioCyc:   SSOL273057:SSO2222-MONOMER
- HAMAP:   MF_01685
- InterPro:   IPR013027
- InterPro:   IPR022890
- InterPro:   IPR001327
- InterPro:   IPR000103
- PRINTS:   PR00368
- PRINTS:   PR00469

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2

EC number: =1.18.1.2

Molecular weight: Translated: 36543; Mature: 36543

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: NA

Important sites: BINDING 33-33 BINDING 41-41 BINDING 46-46 BINDING 86-86 BINDING 120-120 BINDING 281-281 BINDING 324-324

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEYDIVVIGGGPVGLFGTFYAGLRDMKTLLIDAQDELGGQLVSLYPEKIVYDVGGLAGI
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHEEECCHHHCCCEEECCHHHHEECCCCCCCH
QAYELAQRLIEQAKMFGPDIKVNELADMIEKTNDNMWIVKTDKATYKTKTIFIAAGIGKI
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEECCCEEEEEEEEEECCCHHH
VPSRLGAKGEIEYENRGVYYTVRRKKDFEGKRVLIVGGGDSAVDWALTLAPVAKSVTLIH
HHHHCCCCCEEEECCCCEEEEEECCCCCCCCEEEEEECCCCHHHHEEEHHHHHHHHHEEH
RRDQFRAHERSVKELFRVANVYVWHELKEVKGDGNKVTQAIIFDNRTKEEKVLDVDSVII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHEECCEEEE
SIGYKGDLGNIPKWGVTMKGRDIVVNGRMETNLPGVYAGGDIVQMEGSPKLALIAVGFAH
EEECCCCCCCCCCCCEEECCCEEEEECEEECCCCCEEECCCEEEECCCCCEEEEEEEHHH
AAIAISVAKKYVEPNASLFAGHSSEMDKFKPK
HHHHHHHHHHHHCCCCEEEECCCCCCHHCCCC
>Mature Secondary Structure
MDEYDIVVIGGGPVGLFGTFYAGLRDMKTLLIDAQDELGGQLVSLYPEKIVYDVGGLAGI
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHEEECCHHHCCCEEECCHHHHEECCCCCCCH
QAYELAQRLIEQAKMFGPDIKVNELADMIEKTNDNMWIVKTDKATYKTKTIFIAAGIGKI
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEECCCEEEEEEEEEECCCHHH
VPSRLGAKGEIEYENRGVYYTVRRKKDFEGKRVLIVGGGDSAVDWALTLAPVAKSVTLIH
HHHHCCCCCEEEECCCCEEEEEECCCCCCCCEEEEEECCCCHHHHEEEHHHHHHHHHEEH
RRDQFRAHERSVKELFRVANVYVWHELKEVKGDGNKVTQAIIFDNRTKEEKVLDVDSVII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHEECCEEEE
SIGYKGDLGNIPKWGVTMKGRDIVVNGRMETNLPGVYAGGDIVQMEGSPKLALIAVGFAH
EEECCCCCCCCCCCCEEECCCEEEEECEEECCCCCEEECCCEEEECCCCCEEEEEEEHHH
AAIAISVAKKYVEPNASLFAGHSSEMDKFKPK
HHHHHHHHHHHHCCCCEEEECCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11427726