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The map label for this gene is asd-2 [H]

Identifier: 15898958

GI number: 15898958

Start: 2001586

End: 2002656

Strand: Direct

Name: asd-2 [H]

Synonym: SSO2178

Alternate gene names: 15898958

Gene position: 2001586-2002656 (Clockwise)

Preceding gene: 15898957

Following gene: 15898959

Centisome position: 66.89

GC content: 38.94

Gene sequence:

>1071_bases
ATGAGGAGAACACTTAAAGCAGCTATCTTGGGATCCACAGGATTAGTTGGAATAGAATATGTCAGAATGTTAGCTAATCA
TCCATACATTAAAGTAGGGTATCTAGCTGGAAAAGGTTCAGTAGGTAAACCTTATGGAGAAGTCGTGAGATGGCAAACTA
TAGGTCAAGTTCCAACTGAAATAGCCGACATGGAAGTTAAACCGACTGATCCGAAATTAATGGATGATGTAGATATTGTA
TTTTCACCCTTACCTCAAGGTGCTGCAGGTCCAGTAGAGGAGGAATTCGCTAAACATGGATTCCCGGTAATCAGCAATTC
TCCAGATCATAGATTTGATCCCGACGTACCCTTGCTAATTCCGGAAGTAAATCCACATACAATATCACTTATTGATAAGC
AGAGAGAAAGACGTGACTGGAGGGGTTTTATAGTTACAACACCATTATGCACTGCCCAAGGGGCTGCAATTCCATTAGCA
CCAATATATATGAACTTTAAAATAGATAGTAGCTTGATAACAACTATTCAATCGTTATCTGGTGCCGGTTATCCTGGAAT
ACCTTCGCTTGATGTGATAGATAATGTATTGCCTTTAGGTGACAATTACGATAATAAGACTGTTAAGGAGATTAGCAGGA
TTTTAAGCGAGACGAAAAGGATGGTTGATGATGATGATAATAACCTATCATTAGGTGCAACAACTCATAGGGTAGCAACT
ATTCATGGCCACTATGAGGTAATTTATATCACATTTAAAGAAGATGTCACTGTAGAAAAGATTGGAGAGACTTTAGATTC
GTTTAGAGGAGAACCACAAAACCTAAAACTACCTACGGCACCAGACAAACCTATACTTTTGATTAATCAAGATGCGAGAC
CTCAAGTATATTTTGACAGATGGGCAGGGAATCCACCCGGTATGAGCGTAGTAGTTGGGAGATTAGGCCAAATAAATAGG
AGAACTATTAGGTTAGTATCAGTGATCCATAACACTGTAAGAGGAGCTGCTGGAGGAGGGATATTAGCAACTGAACTGTT
AATTGAGAAAGGATATATTGATAAAAGGTAA

Upstream 100 bases:

>100_bases
TTCTCACTCATTTTTTTATATAATAGACTCTAAAATACTATAACTTATACTTTTAAAATAAGCTTATATCCCAGTAACTC
TATATATTATGTGAGTAAAA

Downstream 100 bases:

>100_bases
CTCTTTTTTACTATCCTTTCTTATTCTACACTATGAATTTTATTACATTTGCTGAGAAGTTAGGAATTGATCGGGAAGCT
GCGATAAAAGTTTATAGATT

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MRRTLKAAILGSTGLVGIEYVRMLANHPYIKVGYLAGKGSVGKPYGEVVRWQTIGQVPTEIADMEVKPTDPKLMDDVDIV
FSPLPQGAAGPVEEEFAKHGFPVISNSPDHRFDPDVPLLIPEVNPHTISLIDKQRERRDWRGFIVTTPLCTAQGAAIPLA
PIYMNFKIDSSLITTIQSLSGAGYPGIPSLDVIDNVLPLGDNYDNKTVKEISRILSETKRMVDDDDNNLSLGATTHRVAT
IHGHYEVIYITFKEDVTVEKIGETLDSFRGEPQNLKLPTAPDKPILLINQDARPQVYFDRWAGNPPGMSVVVGRLGQINR
RTIRLVSVIHNTVRGAAGGGILATELLIEKGYIDKR

Sequences:

>Translated_356_residues
MRRTLKAAILGSTGLVGIEYVRMLANHPYIKVGYLAGKGSVGKPYGEVVRWQTIGQVPTEIADMEVKPTDPKLMDDVDIV
FSPLPQGAAGPVEEEFAKHGFPVISNSPDHRFDPDVPLLIPEVNPHTISLIDKQRERRDWRGFIVTTPLCTAQGAAIPLA
PIYMNFKIDSSLITTIQSLSGAGYPGIPSLDVIDNVLPLGDNYDNKTVKEISRILSETKRMVDDDDNNLSLGATTHRVAT
IHGHYEVIYITFKEDVTVEKIGETLDSFRGEPQNLKLPTAPDKPILLINQDARPQVYFDRWAGNPPGMSVVVGRLGQINR
RTIRLVSVIHNTVRGAAGGGILATELLIEKGYIDKR
>Mature_356_residues
MRRTLKAAILGSTGLVGIEYVRMLANHPYIKVGYLAGKGSVGKPYGEVVRWQTIGQVPTEIADMEVKPTDPKLMDDVDIV
FSPLPQGAAGPVEEEFAKHGFPVISNSPDHRFDPDVPLLIPEVNPHTISLIDKQRERRDWRGFIVTTPLCTAQGAAIPLA
PIYMNFKIDSSLITTIQSLSGAGYPGIPSLDVIDNVLPLGDNYDNKTVKEISRILSETKRMVDDDDNNLSLGATTHRVAT
IHGHYEVIYITFKEDVTVEKIGETLDSFRGEPQNLKLPTAPDKPILLINQDARPQVYFDRWAGNPPGMSVVVGRLGQINR
RTIRLVSVIHNTVRGAAGGGILATELLIEKGYIDKR

Specific function: This enzyme catalyzes the second step in the common metabolic pathway to synthesize Thr and Met from Asp [H]

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320362, Length=361, Percent_Identity=32.9639889196676, Blast_Score=193, Evalue=3e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR005676
- InterPro:   IPR012080
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 39161; Mature: 39161

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRTLKAAILGSTGLVGIEYVRMLANHPYIKVGYLAGKGSVGKPYGEVVRWQTIGQVPTE
CCCCCEEEEECCCCCHHHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHEEHHHHCCCCHH
IADMEVKPTDPKLMDDVDIVFSPLPQGAAGPVEEEFAKHGFPVISNSPDHRFDPDVPLLI
HHCCEECCCCCCHHCCHHHHCCCCCCCCCCCHHHHHHHCCCCEECCCCCCCCCCCCCEEE
PEVNPHTISLIDKQRERRDWRGFIVTTPLCTAQGAAIPLAPIYMNFKIDSSLITTIQSLS
ECCCCCEEEEHHHHHHHHCCCCEEEECCCCCCCCCCCEEEEEEEEEEECHHHHHHHHHHC
GAGYPGIPSLDVIDNVLPLGDNYDNKTVKEISRILSETKRMVDDDDNNLSLGATTHRVAT
CCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEECCCEEEEEE
IHGHYEVIYITFKEDVTVEKIGETLDSFRGEPQNLKLPTAPDKPILLINQDARPQVYFDR
EECCEEEEEEEECCCCCHHHHHHHHHHHCCCCCCEECCCCCCCCEEEECCCCCCCEEEEC
WAGNPPGMSVVVGRLGQINRRTIRLVSVIHNTVRGAAGGGILATELLIEKGYIDKR
CCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRRTLKAAILGSTGLVGIEYVRMLANHPYIKVGYLAGKGSVGKPYGEVVRWQTIGQVPTE
CCCCCEEEEECCCCCHHHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHEEHHHHCCCCHH
IADMEVKPTDPKLMDDVDIVFSPLPQGAAGPVEEEFAKHGFPVISNSPDHRFDPDVPLLI
HHCCEECCCCCCHHCCHHHHCCCCCCCCCCCHHHHHHHCCCCEECCCCCCCCCCCCCEEE
PEVNPHTISLIDKQRERRDWRGFIVTTPLCTAQGAAIPLAPIYMNFKIDSSLITTIQSLS
ECCCCCEEEEHHHHHHHHCCCCEEEECCCCCCCCCCCEEEEEEEEEEECHHHHHHHHHHC
GAGYPGIPSLDVIDNVLPLGDNYDNKTVKEISRILSETKRMVDDDDNNLSLGATTHRVAT
CCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEECCCEEEEEE
IHGHYEVIYITFKEDVTVEKIGETLDSFRGEPQNLKLPTAPDKPILLINQDARPQVYFDR
EECCEEEEEEEECCCCCHHHHHHHHHHHCCCCCCEECCCCCCCCEEEECCCCCCCEEEEC
WAGNPPGMSVVVGRLGQINRRTIRLVSVIHNTVRGAAGGGILATELLIEKGYIDKR
CCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]