Click here to switch to the map view.

The map label for this gene is cutA-2 [H]

Identifier: 15898875

GI number: 15898875

Start: 1904282

End: 1906378

Strand: Direct

Name: cutA-2 [H]

Synonym: SSO2091

Alternate gene names: 15898875

Gene position: 1904282-1906378 (Clockwise)

Preceding gene: 15898874

Following gene: 15898876

Centisome position: 63.64

GC content: 40.3

Gene sequence:

>2097_bases
ATGAGAAGAATAGACGCATATGACCTATTAATAGGAAAGGGTAATTATGTAGATGATATATCGTATAAGGGAAAATACGC
AGTATTTATCAGAAGCCCATACGCCCATGCTAGAATAGTCAACATCAATAAAGAAGATGCAGAAAGAAGAGGCGCATTAG
TTCTAACAGGTAAAGATTTAGTATCTAGAAATGTAGAATCTGGCGAAAGAGAAGGAGCAAGTTTGACAACTCCATTAATG
GCGATAAATAAGGCACTATACGTTGGCCAACCAGTAGCTTTAGTTATTGCAAATGATCCATATGAGGCTACGGATTTAGC
GGAATTAGTTCAAATCGATTATGAACCTTTGGAAGGCATAGGAAATATTGAAAAAGCTTTAGAGAATAAGGTAACAGTAT
TTGAGGATTTGAAGACAAACGTAGTAAGAGAACAAACCTTTGAATTCGGAAAACTGAGCACACAAGGTAGGCACTTAGAA
TTAGACCTATACTGGTCTAGAAGCTCTGGAAATCCAATAGAACCTTATGGGGCAATCACAATTCCAACAGATGATAGTTT
GACCATAATTTCGAATCAGCAAGCAGGGAACGTAGTATCCAACGAAATACAGAAGGCGTTAGGAGTTAAGGTAGTACATA
AAAACGCTAGGCAAGGAGGAAGCTTCGGTGAGAAGTTCTCCCTAGTCAGATACTTGACAGTATTAGGCTTTGCAGCATTG
AAGTTTAAAGTACCAATAAAGTGGATTGAGACTAGAAATGAGCATTTAATGGCATCAAATGGAAGTGGACCAGAGAGGAA
ATTCAAAATCCACGCCTATTATTCCTCTGATGGAAGGGTAAATAGTTTAGATGTTCACATATGGGAAGACGTTGGTGCCT
CTAGGGATGCTGGTCAACCTTTTAAACCTTTAGCGTTCTTAACTGGACCATATAAAATTGGAGGTATAAGATATACTGGA
ACTTTAGTTGCCACAAATAAGAACCCAGCTGGAGCATTTAGAGGTGCTGGCACTCCGCCTCATACTTGGGCGCTAGAAAG
AACAATGGATGCCATAGCTGATGACTTAGGTATTAGTAAGGCTGATGTGAGAAAGATTAACGCAATAGATACTTTCCCCT
ACGATTCTGGATTTGCATACTACGATTCTGGAAATCCAAGAGGCTTACTAGATTTAGCGTTATCAAGAAAAGACATCTTT
GCATTGAGGAATAAGAACACTGGAGTAGGTTTAGCGTTATCAACTGATCCCAGTACACCTTCTGGCAGCGAGAGAGTGAA
AATTAAGGTTAAGAATAATAAAATTGTAATCGGTTTGGGATTTGGTCCGGAGGGTCAAGGTAACGAGCATTCAGCAGTGG
TAATGGCTTCAAGACTATTAGGGATAACCCCAGATGACGTCGCATATGAGATTCTAGATAACACTGAATTGCCAACGTCC
TTTGGACCTGGAGGAAGTAGAATGGCGATTTACACTTTTGGAGCTGTTTCTGGGGCAGTGGAGGAGCTAAAAGCTAGATT
GAGGAGGAAGGCAGAAGTTGTCCTAAACGATAAAGTCATTGATTACAGAGATGGGTACTTTATAGGAGAAAACGGAGGAA
AAGTTAGAATTACGTCACTCGAGGGAGAAGAGGTCGACTTCACTTACACATTACAAGGTAAGTATAGATTCAATGCCTAT
CCATTCGCTTGTGACTTGGCAGTTGTTAGAATTGAAGACGGCAAGATAAAGCCAATAAAACACGTAGTTTACATTGATCC
AGGAACTCCGATAGACGAGGATTTAGTAAAGGAACAAGTAATAGGAGGTACTGCAATTGGAATTTCTCTAGCATTATACG
AACATTACGTATACGATGAGAACGCTAACTTACTAACTACAAACCTAGCGGACTATGGAATGCCAACCGCTGCTGATTTA
CCGGAAATAGAGGTCAACATAGTTCCGACTCCCTCTCCATCAACTCCTTATGGAGCTAAGGGAATAGGGGAAATCCCAGT
TGGAATAGCTGCAGCTGCAGTAACTAGCGCCATTGAAGACGTTATAAAGAGAAGGATAAATAGAGTTCCAGTAAGCCTAG
AAGACCTTTTTGAATAG

Upstream 100 bases:

>100_bases
TACGTATAGTGTGAAGAGGTGCGGTGAACCTTGGACGTCAATACTGAGTGAAGTTTTCTTGCCCTTTAAAGTCTGACGAA
GTATAACTAACAAACAAGCA

Downstream 100 bases:

>100_bases
GAGTTTTAATATCATAATATCATTTAAATTTATTTTTTGGAACATGAAGAGTAAACCTATGAATGTAATTTTCGATGTAC
TAAACGAGATTCATGGGTTT

Product: carbon monoxide dehydrogenase, large chain (cutA-2)

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 698; Mature: 698

Protein sequence:

>698_residues
MRRIDAYDLLIGKGNYVDDISYKGKYAVFIRSPYAHARIVNINKEDAERRGALVLTGKDLVSRNVESGEREGASLTTPLM
AINKALYVGQPVALVIANDPYEATDLAELVQIDYEPLEGIGNIEKALENKVTVFEDLKTNVVREQTFEFGKLSTQGRHLE
LDLYWSRSSGNPIEPYGAITIPTDDSLTIISNQQAGNVVSNEIQKALGVKVVHKNARQGGSFGEKFSLVRYLTVLGFAAL
KFKVPIKWIETRNEHLMASNGSGPERKFKIHAYYSSDGRVNSLDVHIWEDVGASRDAGQPFKPLAFLTGPYKIGGIRYTG
TLVATNKNPAGAFRGAGTPPHTWALERTMDAIADDLGISKADVRKINAIDTFPYDSGFAYYDSGNPRGLLDLALSRKDIF
ALRNKNTGVGLALSTDPSTPSGSERVKIKVKNNKIVIGLGFGPEGQGNEHSAVVMASRLLGITPDDVAYEILDNTELPTS
FGPGGSRMAIYTFGAVSGAVEELKARLRRKAEVVLNDKVIDYRDGYFIGENGGKVRITSLEGEEVDFTYTLQGKYRFNAY
PFACDLAVVRIEDGKIKPIKHVVYIDPGTPIDEDLVKEQVIGGTAIGISLALYEHYVYDENANLLTTNLADYGMPTAADL
PEIEVNIVPTPSPSTPYGAKGIGEIPVGIAAAAVTSAIEDVIKRRINRVPVSLEDLFE

Sequences:

>Translated_698_residues
MRRIDAYDLLIGKGNYVDDISYKGKYAVFIRSPYAHARIVNINKEDAERRGALVLTGKDLVSRNVESGEREGASLTTPLM
AINKALYVGQPVALVIANDPYEATDLAELVQIDYEPLEGIGNIEKALENKVTVFEDLKTNVVREQTFEFGKLSTQGRHLE
LDLYWSRSSGNPIEPYGAITIPTDDSLTIISNQQAGNVVSNEIQKALGVKVVHKNARQGGSFGEKFSLVRYLTVLGFAAL
KFKVPIKWIETRNEHLMASNGSGPERKFKIHAYYSSDGRVNSLDVHIWEDVGASRDAGQPFKPLAFLTGPYKIGGIRYTG
TLVATNKNPAGAFRGAGTPPHTWALERTMDAIADDLGISKADVRKINAIDTFPYDSGFAYYDSGNPRGLLDLALSRKDIF
ALRNKNTGVGLALSTDPSTPSGSERVKIKVKNNKIVIGLGFGPEGQGNEHSAVVMASRLLGITPDDVAYEILDNTELPTS
FGPGGSRMAIYTFGAVSGAVEELKARLRRKAEVVLNDKVIDYRDGYFIGENGGKVRITSLEGEEVDFTYTLQGKYRFNAY
PFACDLAVVRIEDGKIKPIKHVVYIDPGTPIDEDLVKEQVIGGTAIGISLALYEHYVYDENANLLTTNLADYGMPTAADL
PEIEVNIVPTPSPSTPYGAKGIGEIPVGIAAAAVTSAIEDVIKRRINRVPVSLEDLFE
>Mature_698_residues
MRRIDAYDLLIGKGNYVDDISYKGKYAVFIRSPYAHARIVNINKEDAERRGALVLTGKDLVSRNVESGEREGASLTTPLM
AINKALYVGQPVALVIANDPYEATDLAELVQIDYEPLEGIGNIEKALENKVTVFEDLKTNVVREQTFEFGKLSTQGRHLE
LDLYWSRSSGNPIEPYGAITIPTDDSLTIISNQQAGNVVSNEIQKALGVKVVHKNARQGGSFGEKFSLVRYLTVLGFAAL
KFKVPIKWIETRNEHLMASNGSGPERKFKIHAYYSSDGRVNSLDVHIWEDVGASRDAGQPFKPLAFLTGPYKIGGIRYTG
TLVATNKNPAGAFRGAGTPPHTWALERTMDAIADDLGISKADVRKINAIDTFPYDSGFAYYDSGNPRGLLDLALSRKDIF
ALRNKNTGVGLALSTDPSTPSGSERVKIKVKNNKIVIGLGFGPEGQGNEHSAVVMASRLLGITPDDVAYEILDNTELPTS
FGPGGSRMAIYTFGAVSGAVEELKARLRRKAEVVLNDKVIDYRDGYFIGENGGKVRITSLEGEEVDFTYTLQGKYRFNAY
PFACDLAVVRIEDGKIKPIKHVVYIDPGTPIDEDLVKEQVIGGTAIGISLALYEHYVYDENANLLTTNLADYGMPTAADL
PEIEVNIVPTPSPSTPYGAKGIGEIPVGIAAAAVTSAIEDVIKRRINRVPVSLEDLFE

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI71773480, Length=724, Percent_Identity=23.7569060773481, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI91823271, Length=711, Percent_Identity=23.4880450070323, Blast_Score=110, Evalue=6e-24,
Organism=Escherichia coli, GI1789230, Length=766, Percent_Identity=25.5874673629243, Blast_Score=153, Evalue=4e-38,
Organism=Escherichia coli, GI1789246, Length=762, Percent_Identity=21.9160104986877, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI1786478, Length=410, Percent_Identity=23.9024390243902, Blast_Score=89, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17540638, Length=714, Percent_Identity=23.9495798319328, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17539860, Length=718, Percent_Identity=23.6768802228412, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI32566215, Length=559, Percent_Identity=22.7191413237925, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI17737937, Length=718, Percent_Identity=22.9805013927577, Blast_Score=93, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24647193, Length=714, Percent_Identity=21.8487394957983, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 76118; Mature: 76118

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRIDAYDLLIGKGNYVDDISYKGKYAVFIRSPYAHARIVNINKEDAERRGALVLTGKDL
CCCCCEEEEEEECCCEECCCCCCCEEEEEEECCCCCEEEEECCHHHHHHCCEEEEECHHH
VSRNVESGEREGASLTTPLMAINKALYVGQPVALVIANDPYEATDLAELVQIDYEPLEGI
HHCCCCCCCCCCCCCCCHHHHHHHHEEECCCEEEEEECCCCCHHHHHHHHHCCCCHHCCC
GNIEKALENKVTVFEDLKTNVVREQTFEFGKLSTQGRHLELDLYWSRSSGNPIEPYGAIT
CHHHHHHHCCCEEEHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCCCCCEEEE
IPTDDSLTIISNQQAGNVVSNEIQKALGVKVVHKNARQGGSFGEKFSLVRYLTVLGFAAL
ECCCCCEEEEECCCCCCHHHHHHHHHHCEEEEECCCCCCCCCCHHHHHHHHHHHHHHEEE
KFKVPIKWIETRNEHLMASNGSGPERKFKIHAYYSSDGRVNSLDVHIWEDVGASRDAGQP
EEEECEEEEECCCCEEEECCCCCCCEEEEEEEEECCCCCEEEEEEEEEECCCCCCCCCCC
FKPLAFLTGPYKIGGIRYTGTLVATNKNPAGAFRGAGTPPHTWALERTMDAIADDLGISK
CCCEEEEECCEEECCEEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCH
ADVRKINAIDTFPYDSGFAYYDSGNPRGLLDLALSRKDIFALRNKNTGVGLALSTDPSTP
HHHEEEECEECCCCCCCEEEEECCCCCEEEEEEECCCEEEEEECCCCCEEEEEECCCCCC
SGSERVKIKVKNNKIVIGLGFGPEGQGNEHSAVVMASRLLGITPDDVAYEILDNTELPTS
CCCCEEEEEEECCEEEEEECCCCCCCCCCCHHEEEEHHHCCCCCHHHHHEECCCCCCCCC
FGPGGSRMAIYTFGAVSGAVEELKARLRRKAEVVLNDKVIDYRDGYFIGENGGKVRITSL
CCCCCCEEEEEEECCHHHHHHHHHHHHHHCEEEEECCCEEEECCCEEECCCCCEEEEEEE
EGEEVDFTYTLQGKYRFNAYPFACDLAVVRIEDGKIKPIKHVVYIDPGTPIDEDLVKEQV
CCCEEEEEEEEECEEEECCCCEEEEEEEEEECCCCCCEEEEEEEECCCCCCCHHHHHHHH
IGGTAIGISLALYEHYVYDENANLLTTNLADYGMPTAADLPEIEVNIVPTPSPSTPYGAK
CCCCHHHEEEEEEEEEEECCCCCEEEECHHHCCCCCCCCCCCEEEEEEECCCCCCCCCCC
GIGEIPVGIAAAAVTSAIEDVIKRRINRVPVSLEDLFE
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCC
>Mature Secondary Structure
MRRIDAYDLLIGKGNYVDDISYKGKYAVFIRSPYAHARIVNINKEDAERRGALVLTGKDL
CCCCCEEEEEEECCCEECCCCCCCEEEEEEECCCCCEEEEECCHHHHHHCCEEEEECHHH
VSRNVESGEREGASLTTPLMAINKALYVGQPVALVIANDPYEATDLAELVQIDYEPLEGI
HHCCCCCCCCCCCCCCCHHHHHHHHEEECCCEEEEEECCCCCHHHHHHHHHCCCCHHCCC
GNIEKALENKVTVFEDLKTNVVREQTFEFGKLSTQGRHLELDLYWSRSSGNPIEPYGAIT
CHHHHHHHCCCEEEHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCCCCCEEEE
IPTDDSLTIISNQQAGNVVSNEIQKALGVKVVHKNARQGGSFGEKFSLVRYLTVLGFAAL
ECCCCCEEEEECCCCCCHHHHHHHHHHCEEEEECCCCCCCCCCHHHHHHHHHHHHHHEEE
KFKVPIKWIETRNEHLMASNGSGPERKFKIHAYYSSDGRVNSLDVHIWEDVGASRDAGQP
EEEECEEEEECCCCEEEECCCCCCCEEEEEEEEECCCCCEEEEEEEEEECCCCCCCCCCC
FKPLAFLTGPYKIGGIRYTGTLVATNKNPAGAFRGAGTPPHTWALERTMDAIADDLGISK
CCCEEEEECCEEECCEEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCH
ADVRKINAIDTFPYDSGFAYYDSGNPRGLLDLALSRKDIFALRNKNTGVGLALSTDPSTP
HHHEEEECEECCCCCCCEEEEECCCCCEEEEEEECCCEEEEEECCCCCEEEEEECCCCCC
SGSERVKIKVKNNKIVIGLGFGPEGQGNEHSAVVMASRLLGITPDDVAYEILDNTELPTS
CCCCEEEEEEECCEEEEEECCCCCCCCCCCHHEEEEHHHCCCCCHHHHHEECCCCCCCCC
FGPGGSRMAIYTFGAVSGAVEELKARLRRKAEVVLNDKVIDYRDGYFIGENGGKVRITSL
CCCCCCEEEEEEECCHHHHHHHHHHHHHHCEEEEECCCEEEECCCEEECCCCCEEEEEEE
EGEEVDFTYTLQGKYRFNAYPFACDLAVVRIEDGKIKPIKHVVYIDPGTPIDEDLVKEQV
CCCEEEEEEEEECEEEECCCCEEEEEEEEEECCCCCCEEEEEEEECCCCCCCHHHHHHHH
IGGTAIGISLALYEHYVYDENANLLTTNLADYGMPTAADLPEIEVNIVPTPSPSTPYGAK
CCCCHHHEEEEEEEEEEECCCCCEEEECHHHCCCCCCCCCCCEEEEEEECCCCCCCCCCC
GIGEIPVGIAAAAVTSAIEDVIKRRINRVPVSLEDLFE
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7721710; 2818128; 12515558; 10430865; 12475995 [H]