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The map label for this gene is acaB-3

Identifier: 15898851

GI number: 15898851

Start: 1881105

End: 1882334

Strand: Direct

Name: acaB-3

Synonym: SSO2062

Alternate gene names: NA

Gene position: 1881105-1882334 (Clockwise)

Preceding gene: 15898850

Following gene: 15898852

Centisome position: 62.87

GC content: 41.87

Gene sequence:

>1230_bases
TTGGCGTGGAATTCCCACGCTTACTGGATCAGTCGTGGTGGTGGAAAAGCCATGAAGGTAAATATTCATTTAAATAAAAG
GGTTGCAATAATAGGAGCTGGCTTAACTCTATTTAGGAGAAGACTACTAGAAACTCCACAAGAAATAGCATGGGAGGCTG
CAAGTAAGGCACTGGACGAAGCTGGACTAGAGTTAAAGGATATCGACTGTGTCGTTATTGGAAGTGCACCAGATGCTTTT
GATGGGGTTAACCTAAAGGGTGAATACTTATCACATGGTGCTGGAGGAATCAAGAAGCCAGTAAGTAGAGTTTATGTGGG
TGGTGCTACTGGAGTTATGACTGCAATAACAGGCTGGTATCATGTCGCCAGTGGGTTGTGCCAGAAAGTATTGGCTGTAG
CTGAGGAAAAGATGAGTCCAGCTAGACCTCATCCACAATCAATATTCAGATATATATGGGATCCAATTTTAGAAAAGCCC
TTGAATCCTAATCTGATATGGATATTCGCAATGGAAATGCACAGATATATGGCAACTTATGGAATTAAAAAAGAGGAGAT
TGCACTAGTCTCTGTAAAGAACAAAAGGAATGCAATAAACAACCCATACGCACAACTAGGTTCAAATATAACAGTAGAAG
ACGTACTAAAGAGTGAAGTCTTAGTTTGGCCAGTTCAACTCTTAGATGTTAGCCCAGTTAGTGATGGCGGGGCAGCGATT
GTATTGGCCTCAGAAGACGTTGCAAGAAGGTACACTGATACACCGGTATGGGTTGAAGGTGTTGGATGGACCTTAGATAA
TACGGAATGGCCTGCCAGAGATTTAGCCTATGCTAGATATGTGGAATTCGCAGCTAGAATGGCTTATAAGATGGCTGGGA
TTGAGAGGCCAAATAAGGAAATAGATGTTGCTGAACCATATGATCCGTTTGATTACAAAGAACTACATCATTTAGAGGCA
TTACAATTAGCTAAAAGGGGAGAAGCTCCAAAATTATTAAAGGAGGGAGTATTCGACATTGATGGCGATATACCCAGTAG
TCCTAGTGGAGGTTTACTGGGAGTGGGTAATCCTATTGCAGCTGCTGGCTTAATGAAGGTTATAAGTATATATTGGCAAC
TTAAGGGGATTGCTGGAAAAATGCAAGTTAAGAGACCAGTACATACTGGCGTAGCCCAAGCTTGGGGAGATTTAATGCAA
GCGGGTACGGTTATAGTTTTACGTAATTGA

Upstream 100 bases:

>100_bases
TGGCTAAAGGAGTTCCTTTAGAAGCTTCCGGTTTTTCATTATTGCTAGACGCGATAGAGTATATTAAGCAAGGGAAGGGT
GAAAGAGCTGTAGTCGCGTC

Downstream 100 bases:

>100_bases
GGGATATGAGATGGTAACTCCTCTTAAAGAAGAAGAATTAAGTAAACATTACATAATATCATATAAGCCAAATGCTAAGT
ACGCATACACTGCGGGACAA

Product: acetyl-CoA acetyltransferase

Products: CoA; 3-oxoacyl-CoA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MAWNSHAYWISRGGGKAMKVNIHLNKRVAIIGAGLTLFRRRLLETPQEIAWEAASKALDEAGLELKDIDCVVIGSAPDAF
DGVNLKGEYLSHGAGGIKKPVSRVYVGGATGVMTAITGWYHVASGLCQKVLAVAEEKMSPARPHPQSIFRYIWDPILEKP
LNPNLIWIFAMEMHRYMATYGIKKEEIALVSVKNKRNAINNPYAQLGSNITVEDVLKSEVLVWPVQLLDVSPVSDGGAAI
VLASEDVARRYTDTPVWVEGVGWTLDNTEWPARDLAYARYVEFAARMAYKMAGIERPNKEIDVAEPYDPFDYKELHHLEA
LQLAKRGEAPKLLKEGVFDIDGDIPSSPSGGLLGVGNPIAAAGLMKVISIYWQLKGIAGKMQVKRPVHTGVAQAWGDLMQ
AGTVIVLRN

Sequences:

>Translated_409_residues
MAWNSHAYWISRGGGKAMKVNIHLNKRVAIIGAGLTLFRRRLLETPQEIAWEAASKALDEAGLELKDIDCVVIGSAPDAF
DGVNLKGEYLSHGAGGIKKPVSRVYVGGATGVMTAITGWYHVASGLCQKVLAVAEEKMSPARPHPQSIFRYIWDPILEKP
LNPNLIWIFAMEMHRYMATYGIKKEEIALVSVKNKRNAINNPYAQLGSNITVEDVLKSEVLVWPVQLLDVSPVSDGGAAI
VLASEDVARRYTDTPVWVEGVGWTLDNTEWPARDLAYARYVEFAARMAYKMAGIERPNKEIDVAEPYDPFDYKELHHLEA
LQLAKRGEAPKLLKEGVFDIDGDIPSSPSGGLLGVGNPIAAAGLMKVISIYWQLKGIAGKMQVKRPVHTGVAQAWGDLMQ
AGTVIVLRN
>Mature_408_residues
AWNSHAYWISRGGGKAMKVNIHLNKRVAIIGAGLTLFRRRLLETPQEIAWEAASKALDEAGLELKDIDCVVIGSAPDAFD
GVNLKGEYLSHGAGGIKKPVSRVYVGGATGVMTAITGWYHVASGLCQKVLAVAEEKMSPARPHPQSIFRYIWDPILEKPL
NPNLIWIFAMEMHRYMATYGIKKEEIALVSVKNKRNAINNPYAQLGSNITVEDVLKSEVLVWPVQLLDVSPVSDGGAAIV
LASEDVARRYTDTPVWVEGVGWTLDNTEWPARDLAYARYVEFAARMAYKMAGIERPNKEIDVAEPYDPFDYKELHHLEAL
QLAKRGEAPKLLKEGVFDIDGDIPSSPSGGLLGVGNPIAAAGLMKVISIYWQLKGIAGKMQVKRPVHTGVAQAWGDLMQA
GTVIVLRN

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI19923233, Length=379, Percent_Identity=30.0791556728232, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI302344760, Length=376, Percent_Identity=30.0531914893617, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI302344767, Length=302, Percent_Identity=31.4569536423841, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI302344762, Length=369, Percent_Identity=28.1842818428184, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI55956775, Length=349, Percent_Identity=26.9340974212034, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17537653, Length=393, Percent_Identity=25.6997455470738, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI19921506, Length=376, Percent_Identity=30.3191489361702, Blast_Score=137, Evalue=9e-33,
Organism=Drosophila melanogaster, GI24585051, Length=378, Percent_Identity=29.8941798941799, Blast_Score=131, Evalue=9e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: 2.3.1.16

Molecular weight: Translated: 44865; Mature: 44734

Theoretical pI: Translated: 7.74; Mature: 7.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWNSHAYWISRGGGKAMKVNIHLNKRVAIIGAGLTLFRRRLLETPQEIAWEAASKALDE
CCCCCCEEEEECCCCCEEEEEEEECCEEEEEECCHHHHHHHHHCCHHHHHHHHHHHHHHH
AGLELKDIDCVVIGSAPDAFDGVNLKGEYLSHGAGGIKKPVSRVYVGGATGVMTAITGWY
CCCEEECCCEEEECCCCCCCCCCCCCHHHHHCCCCCHHHHHHHEEECCCHHHHHHHHHHH
HVASGLCQKVLAVAEEKMSPARPHPQSIFRYIWDPILEKPLNPNLIWIFAMEMHRYMATY
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHH
GIKKEEIALVSVKNKRNAINNPYAQLGSNITVEDVLKSEVLVWPVQLLDVSPVSDGGAAI
CCCHHHEEEEEECCCCCCCCCCHHHHCCCCCHHHHHHCCCEEEEEEHEEECCCCCCCCEE
VLASEDVARRYTDTPVWVEGVGWTLDNTEWPARDLAYARYVEFAARMAYKMAGIERPNKE
EEECHHHHHHHCCCCEEEEECCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
IDVAEPYDPFDYKELHHLEALQLAKRGEAPKLLKEGVFDIDGDIPSSPSGGLLGVGNPIA
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCCEEECCCHHH
AAGLMKVISIYWQLKGIAGKMQVKRPVHTGVAQAWGDLMQAGTVIVLRN
HHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHCCCEEEEEC
>Mature Secondary Structure 
AWNSHAYWISRGGGKAMKVNIHLNKRVAIIGAGLTLFRRRLLETPQEIAWEAASKALDE
CCCCCEEEEECCCCCEEEEEEEECCEEEEEECCHHHHHHHHHCCHHHHHHHHHHHHHHH
AGLELKDIDCVVIGSAPDAFDGVNLKGEYLSHGAGGIKKPVSRVYVGGATGVMTAITGWY
CCCEEECCCEEEECCCCCCCCCCCCCHHHHHCCCCCHHHHHHHEEECCCHHHHHHHHHHH
HVASGLCQKVLAVAEEKMSPARPHPQSIFRYIWDPILEKPLNPNLIWIFAMEMHRYMATY
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHH
GIKKEEIALVSVKNKRNAINNPYAQLGSNITVEDVLKSEVLVWPVQLLDVSPVSDGGAAI
CCCHHHEEEEEECCCCCCCCCCHHHHCCCCCHHHHHHCCCEEEEEEHEEECCCCCCCCEE
VLASEDVARRYTDTPVWVEGVGWTLDNTEWPARDLAYARYVEFAARMAYKMAGIERPNKE
EEECHHHHHHHCCCCEEEEECCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
IDVAEPYDPFDYKELHHLEALQLAKRGEAPKLLKEGVFDIDGDIPSSPSGGLLGVGNPIA
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCCEEECCCHHH
AAGLMKVISIYWQLKGIAGKMQVKRPVHTGVAQAWGDLMQAGTVIVLRN
HHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acetyl-CoA

Specific reaction: acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]