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The map label for this gene is pcp-like [H]

Identifier: 15898423

GI number: 15898423

Start: 1453219

End: 1453848

Strand: Reverse

Name: pcp-like [H]

Synonym: SSO1607

Alternate gene names: 15898423

Gene position: 1453848-1453219 (Counterclockwise)

Preceding gene: 15898425

Following gene: 15898421

Centisome position: 48.59

GC content: 38.57

Gene sequence:

>630_bases
ATGACAGTCCTCTTGTTTGGCTTCGAACCCTTTTTGGAATACAAGGAAAATCCATCTCAGTTAATTGTTGAAGCCTTAAA
TGGAAGTACCATATTAAAGGAAGAGGTCAAAGGTGTGATATTGCCAGTTGAGTATGAGAAGATAGAGGATTTAATAGTTA
CGAAAATTAGAGAGATGAAACCAATATTAACTTTAGGAATTGGTGTAGCCCCGGGTAGGGCGAAGATAACTCCAGAGAAG
ATAGCCATAAACTACAAGTACTCAAGGGAAGGAGATAACGCTGGGAAGAAGTACAAGGGAGAGAAGATTGACCCCTTAGG
GCAAGACGGTATCTTTACGAATATACCAGTTGAGGACCTCGTAGACTTATTGAATGAAAACGGAATACCAGCTGAATTGA
GCTTAAGTGCTGGTAGCTATCTGTGTAATAACGCAATGTACATCATAATTAGGGAAGCTAGAAAGTACAATAGCTTAGGT
GGTTTCATTCACGTTCCCTTACACGAGTCATATGCCGCGAGAATACAACGACCTATTCCATCTATGAGTTTAGATACTAT
GATAAGGGGAATAAGGTTATCAATGGAATTTATATTAACAAATAAAAAAGAGAATCTTACCTTCTCCTAG

Upstream 100 bases:

>100_bases
CCTAATTAGAAAGACCTTTTCCAAACTCTCCCCAACCTTAATGAGAGAAGAGAGGGAAAATGAAAAATAAAGTTAATAGT
CTAAGCGTTAAAGAGATAGT

Downstream 100 bases:

>100_bases
TTGTCGTTGTCAACAGTTTACAGTAAATTGTGAAGTTTGTGTTATTTTTGACTATTGAAATACCCTTATGAAGGTTTTGA
AAAGTCTAGATCATTTTATT

Product: pyrrolidone-carboxylate peptidase

Products: NA

Alternate protein names: 5-oxoprolyl-peptidase 1; Pyroglutamyl-peptidase I 1; PGP-I 1; Pyrase 1 [H]

Number of amino acids: Translated: 209; Mature: 208

Protein sequence:

>209_residues
MTVLLFGFEPFLEYKENPSQLIVEALNGSTILKEEVKGVILPVEYEKIEDLIVTKIREMKPILTLGIGVAPGRAKITPEK
IAINYKYSREGDNAGKKYKGEKIDPLGQDGIFTNIPVEDLVDLLNENGIPAELSLSAGSYLCNNAMYIIIREARKYNSLG
GFIHVPLHESYAARIQRPIPSMSLDTMIRGIRLSMEFILTNKKENLTFS

Sequences:

>Translated_209_residues
MTVLLFGFEPFLEYKENPSQLIVEALNGSTILKEEVKGVILPVEYEKIEDLIVTKIREMKPILTLGIGVAPGRAKITPEK
IAINYKYSREGDNAGKKYKGEKIDPLGQDGIFTNIPVEDLVDLLNENGIPAELSLSAGSYLCNNAMYIIIREARKYNSLG
GFIHVPLHESYAARIQRPIPSMSLDTMIRGIRLSMEFILTNKKENLTFS
>Mature_208_residues
TVLLFGFEPFLEYKENPSQLIVEALNGSTILKEEVKGVILPVEYEKIEDLIVTKIREMKPILTLGIGVAPGRAKITPEKI
AINYKYSREGDNAGKKYKGEKIDPLGQDGIFTNIPVEDLVDLLNENGIPAELSLSAGSYLCNNAMYIIIREARKYNSLGG
FIHVPLHESYAARIQRPIPSMSLDTMIRGIRLSMEFILTNKKENLTFS

Specific function: Removes 5-oxoproline from various penultimate amino acid residues except L-proline [H]

COG id: COG2039

COG function: function code O; Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C15 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000816
- InterPro:   IPR016125 [H]

Pfam domain/function: PF01470 Peptidase_C15 [H]

EC number: =3.4.19.3 [H]

Molecular weight: Translated: 23405; Mature: 23273

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS01333 PYRASE_GLU ; PS01334 PYRASE_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVLLFGFEPFLEYKENPSQLIVEALNGSTILKEEVKGVILPVEYEKIEDLIVTKIREMK
CEEEEECCCHHHHCCCCHHHHHHHHHCCCEEEHHHHCEEEEEECHHHHHHHHHHHHHHHC
PILTLGIGVAPGRAKITPEKIAINYKYSREGDNAGKKYKGEKIDPLGQDGIFTNIPVEDL
CEEEEECCCCCCCCEECHHHEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEECCCHHHH
VDLLNENGIPAELSLSAGSYLCNNAMYIIIREARKYNSLGGFIHVPLHESYAARIQRPIP
HHHHCCCCCCEEEEECCCCEECCCEEEEEEEECHHCCCCCCEEEECCCHHHHHHHHCCCC
SMSLDTMIRGIRLSMEFILTNKKENLTFS
CCCHHHHHHHHHEEEEEEEECCCCCCCCC
>Mature Secondary Structure 
TVLLFGFEPFLEYKENPSQLIVEALNGSTILKEEVKGVILPVEYEKIEDLIVTKIREMK
EEEEECCCHHHHCCCCHHHHHHHHHCCCEEEHHHHCEEEEEECHHHHHHHHHHHHHHHC
PILTLGIGVAPGRAKITPEKIAINYKYSREGDNAGKKYKGEKIDPLGQDGIFTNIPVEDL
CEEEEECCCCCCCCEECHHHEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEECCCHHHH
VDLLNENGIPAELSLSAGSYLCNNAMYIIIREARKYNSLGGFIHVPLHESYAARIQRPIP
HHHHCCCCCCEEEEECCCCEECCCEEEEEEEECHHCCCCCCEEEECCCHHHHHHHHCCCC
SMSLDTMIRGIRLSMEFILTNKKENLTFS
CCCHHHHHHHHHEEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11427726 [H]