Click here to switch to the map view.

The map label for this gene is shiA [H]

Identifier: 15898365

GI number: 15898365

Start: 1391826

End: 1393118

Strand: Direct

Name: shiA [H]

Synonym: SSO1539

Alternate gene names: 15898365

Gene position: 1391826-1393118 (Clockwise)

Preceding gene: 15898363

Following gene: 15898366

Centisome position: 46.51

GC content: 35.96

Gene sequence:

>1293_bases
GTGGTATACGGCCTAAATAAACAACAATGGCTAGCAGTGTTCTCTACATGGTTAGGATGGTTAATGGATGGTTATACTTC
TATAGCTTATGCTCTAGTTGCAGTTACTATTTCGAAAATATTTTTCCCTTCAACCATAGGAATTCTAGGTTTAATAGCCA
CTTTTGGAGGATTCGCAGTTGGTGCATTAGCTAGGCCCGTAGGATCTTTAGTGTTTGGAAATTTCATAGGAGATAAGATA
GGTAGGAAAAATATGTTAGTTCTAACGATTTTAGGTTTTTCCTTAATAGCCTCTTCTAAAGCCCTATTACCTTCATACGA
AACCGCGGGAATTTTAGCTCCACTATTTCTTTACATCATATTATTTGCTGAGGGCATGTTTGCAGGTGCAGAATATGGAG
GAGGAACCACATTGGCGTTAGAGTCTGTACCTGTAGGCAAGAGAGGATTTATTGGCTCTTTTGTGCAAAGTGGTTTTGGT
ACAGGTTATTTCGTAATATCGTTAGTATACTCAGCTCTGTATAGTATGTTTGGGAATGAAGGATTCCAAACTTTAGGATG
GAGAGTCCTTTTTGCAACTTGCATATTGCCTGGATTAATTACGTTAATAATTAGAAAAATGACAGACGAAAGTCCAATCT
TTAAGGATATGAAAAGTGGGAATGAAGTGGTCAAGATACCTATAAAGGAGTTGTTCAAAATGTCTTATTCCTCAGTATTA
ATAGGGTTAATGATAACAAGTGGATTGTTATACATAAACACTGCTACCTTTTCTTTCTATCCTACAGTGTTGACTATTCA
AGGAATACCAGGGACAATTGTGGGATTAAGCGTTGCTATAATAAATTTGGTTTCCCTTTTTGGAGTTTGGTTTGGCGGAT
TTCTAGCTGATGTCATTAAAAGGGGAAGAAAAGTTCCAATGCTAATTTATTCAATAATATTCATTTTCACCGTATACCCA
GTTTTGTATCTGGGATTGCTAAAGAACGTGTATTTATCCACTATCGTATTTAGCTTACAAGCATTTTTAGAAGCTATGAT
ATTCTCCACTTTACCTGCATTTCTTGCAGAACAGTTTAGTAAAAAATATAGAACTACGGGAGTAGGATTTACATATAATG
GGGGAGCAATAGGAGGTGGTTTTGCTATATCTGCTACTTTAGCGTTATCAACGTACTTAGGCTTACTTTACTCATGGTCG
ATAAACATTATTATAGCTGGGATAATAATGATAATGGGTATTGTCTTAGCAAAAGAAACTTATACTGGAAAAGAAGATCC
AATTTTGAGGTGA

Upstream 100 bases:

>100_bases
ACAATGAGTTTAACATATTATAAAATTGAAGTGATCCACAAAGTTTTAAAAACAGAAAAATTTTTAAATTGTTTATATTA
GTATATATTGAAGATACAAA

Downstream 100 bases:

>100_bases
GATTTTGAAAATAGGTATAAATGGAATAAAAGTAGGTGGATATACTGATGAGAAGTCCAAGTCTGGAGTTACAGTAATAT
TAAGCGAGATTGAAAATAAT

Product: transport protein

Products: Proton [Cytoplasm]; shikimate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MVYGLNKQQWLAVFSTWLGWLMDGYTSIAYALVAVTISKIFFPSTIGILGLIATFGGFAVGALARPVGSLVFGNFIGDKI
GRKNMLVLTILGFSLIASSKALLPSYETAGILAPLFLYIILFAEGMFAGAEYGGGTTLALESVPVGKRGFIGSFVQSGFG
TGYFVISLVYSALYSMFGNEGFQTLGWRVLFATCILPGLITLIIRKMTDESPIFKDMKSGNEVVKIPIKELFKMSYSSVL
IGLMITSGLLYINTATFSFYPTVLTIQGIPGTIVGLSVAIINLVSLFGVWFGGFLADVIKRGRKVPMLIYSIIFIFTVYP
VLYLGLLKNVYLSTIVFSLQAFLEAMIFSTLPAFLAEQFSKKYRTTGVGFTYNGGAIGGGFAISATLALSTYLGLLYSWS
INIIIAGIIMIMGIVLAKETYTGKEDPILR

Sequences:

>Translated_430_residues
MVYGLNKQQWLAVFSTWLGWLMDGYTSIAYALVAVTISKIFFPSTIGILGLIATFGGFAVGALARPVGSLVFGNFIGDKI
GRKNMLVLTILGFSLIASSKALLPSYETAGILAPLFLYIILFAEGMFAGAEYGGGTTLALESVPVGKRGFIGSFVQSGFG
TGYFVISLVYSALYSMFGNEGFQTLGWRVLFATCILPGLITLIIRKMTDESPIFKDMKSGNEVVKIPIKELFKMSYSSVL
IGLMITSGLLYINTATFSFYPTVLTIQGIPGTIVGLSVAIINLVSLFGVWFGGFLADVIKRGRKVPMLIYSIIFIFTVYP
VLYLGLLKNVYLSTIVFSLQAFLEAMIFSTLPAFLAEQFSKKYRTTGVGFTYNGGAIGGGFAISATLALSTYLGLLYSWS
INIIIAGIIMIMGIVLAKETYTGKEDPILR
>Mature_430_residues
MVYGLNKQQWLAVFSTWLGWLMDGYTSIAYALVAVTISKIFFPSTIGILGLIATFGGFAVGALARPVGSLVFGNFIGDKI
GRKNMLVLTILGFSLIASSKALLPSYETAGILAPLFLYIILFAEGMFAGAEYGGGTTLALESVPVGKRGFIGSFVQSGFG
TGYFVISLVYSALYSMFGNEGFQTLGWRVLFATCILPGLITLIIRKMTDESPIFKDMKSGNEVVKIPIKELFKMSYSSVL
IGLMITSGLLYINTATFSFYPTVLTIQGIPGTIVGLSVAIINLVSLFGVWFGGFLADVIKRGRKVPMLIYSIIFIFTVYP
VLYLGLLKNVYLSTIVFSLQAFLEAMIFSTLPAFLAEQFSKKYRTTGVGFTYNGGAIGGGFAISATLALSTYLGLLYSWS
INIIIAGIIMIMGIVLAKETYTGKEDPILR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Escherichia coli, GI1788292, Length=422, Percent_Identity=29.3838862559242, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1790550, Length=251, Percent_Identity=32.6693227091633, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI1789941, Length=365, Percent_Identity=34.2465753424658, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI87082231, Length=493, Percent_Identity=26.1663286004057, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI87082404, Length=394, Percent_Identity=28.1725888324873, Blast_Score=95, Evalue=9e-21,
Organism=Escherichia coli, GI1788942, Length=379, Percent_Identity=29.287598944591, Blast_Score=94, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004736
- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828
- InterPro:   IPR005829 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 46503; Mature: 46503

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCCC
>Mature Secondary Structure
MVYGLNKQQWLAVFSTWLGWLMDGYTSIAYALVAVTISKIFFPSTIGILGLIATFGGFAV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GALARPVGSLVFGNFIGDKIGRKNMLVLTILGFSLIASSKALLPSYETAGILAPLFLYII
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
LFAEGMFAGAEYGGGTTLALESVPVGKRGFIGSFVQSGFGTGYFVISLVYSALYSMFGNE
HHHHHHHCCCCCCCCCEEEEECCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCC
GFQTLGWRVLFATCILPGLITLIIRKMTDESPIFKDMKSGNEVVKIPIKELFKMSYSSVL
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEECHHHHHHHHHHHHH
IGLMITSGLLYINTATFSFYPTVLTIQGIPGTIVGLSVAIINLVSLFGVWFGGFLADVIK
HHHHHHCCEEEEEECHHEEECCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGRKVPMLIYSIIFIFTVYPVLYLGLLKNVYLSTIVFSLQAFLEAMIFSTLPAFLAEQFS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKYRTTGVGFTYNGGAIGGGFAISATLALSTYLGLLYSWSINIIIAGIIMIMGIVLAKET
HHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
YTGKEDPILR
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; shikimate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + shikimate [Periplasm] = Proton [Cytoplasm] + shikimate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9524262; 9097040; 9278503 [H]