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The map label for this gene is iolF [H]

Identifier: 15898146

GI number: 15898146

Start: 1133725

End: 1135116

Strand: Reverse

Name: iolF [H]

Synonym: SSO1305

Alternate gene names: 15898146

Gene position: 1135116-1133725 (Counterclockwise)

Preceding gene: 15898147

Following gene: 15898144

Centisome position: 37.94

GC content: 38.94

Gene sequence:

>1392_bases
ATGAGTGAACCTTCAGATCCTCTAAAAGCACTTGATGAGGCTAAACTATCATCTACGCACTATAGGTGGACAATCCTATC
TGCTTTAGCAGATTTTCTTGATGCAGGAGCGATAGTTGCGGGTGCCGCATCAGTAAGTATATGGGTTTCCCTCTTCCATC
TTAATTCCCTTCTCTTAGGTATAATAGCTGCGTTAAGTCCAAATGCCTTTGCCGCTGGTATAGGAGCTTGGATAGCTGGA
CCACTAGGTGACAGATATGGAAGGAAGGCTATATATACATATGATCTAATCGTATATGCAATAGGTGCAATAATTATATT
ATCAGCAATAAATTACTACATGGTTATTATAGGGTATACTATAGTAGGGTTGGCAGTGGGAGTTGACGTACCAACAAGTT
GGTCACTAATAGCTGAGCTAGCTCCTAAGAGGAATCGCGGAAGATTAATGTCATTTACTAACTTATTCTGGTATATTGGA
CCCATAATAATATTGCTTCTAGGTATAGGCACGGTTCCATTGGGTGTTAACTCCTTTAGAGTCCTATTCGGGTTTTTGAC
AATAGTTGCAATAGTAACATGGGTCCTAAGAAGAGGAATTGCTGAATCCGCTAGATGGGGACTAGTGAAGGGAAAAGAAG
AAGTGGTTAAACAAGCATTAGTACAATTAGGACAAAGCGTAAGTGTAATACCTAAGGCTGAGACCAAAGGTAAGTGGAGT
GATATGTTCAAATATTGGAAAGGATTAGCCTTCATGATCCCAATCTATATTTTCTGGGGAGTACCAGCTGGAACCTTTGG
ATTCTTCTTACCTTTCCTCATAGAAGATTTGTCTATCAAAAGTTCTGTAGTAGGTGATCTAGTTCAAATCGCGTGGTTCG
TGACTGCAATAATTGGAGTTGTTGGAGTATACATGCAGCTATCAGACAAAGTGAATAGGAAGCTATTATATGCAGTAAGT
TCTCTTATTTGCGCAATTGGTTTCGCATTACCTATAGGTTTACCATTCAAGATACTTTGGGTAGCATTATTCAATGTATT
CTTATTTGGATTCGGTCATGGAATGGCGTTATGGCCTCAAACTAGAGTCTGGTCAACGGAGCTTTTCCCAACGGAAATAA
GAAATACGGCTCAAGGTTTTGTATGGGGCTGGATGAGAATAGCATTGGGAATATGGAGTATCTTCGTACCTTCAATAATT
ACTGTAATAGGTTATTCAGCAATAGCTGCAGTAGCTACTTCATTCTTTATACTAAATATTATTTTGGGATTATTAGTGGG
ACCAGATACACATGGAAAATCCTTAGAGGTGGTAATAAAGGACTTTTATGGAGGTAAAGTTCCAGTATCTAAAGTAGTAG
AAGTGAATACAAGACCTCTTGGCAACAAATAA

Upstream 100 bases:

>100_bases
TCTAAGCATATTATGTTTTAAAAATTTACCGGACAGAATACATATCTCCATATAAGTATGGATCCTTACTTATAAACTAT
ATATAACATAAATACCAATA

Downstream 100 bases:

>100_bases
ACTATTAAAGGTCATACTTTAAGCCAAAACCTTTTTCTTCTCCCAATTCGAAATATCCCTTTATTGGCTTAGGAGGATTT
ATCATTCTATCCTCTAGCCA

Product: metabolite transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MSEPSDPLKALDEAKLSSTHYRWTILSALADFLDAGAIVAGAASVSIWVSLFHLNSLLLGIIAALSPNAFAAGIGAWIAG
PLGDRYGRKAIYTYDLIVYAIGAIIILSAINYYMVIIGYTIVGLAVGVDVPTSWSLIAELAPKRNRGRLMSFTNLFWYIG
PIIILLLGIGTVPLGVNSFRVLFGFLTIVAIVTWVLRRGIAESARWGLVKGKEEVVKQALVQLGQSVSVIPKAETKGKWS
DMFKYWKGLAFMIPIYIFWGVPAGTFGFFLPFLIEDLSIKSSVVGDLVQIAWFVTAIIGVVGVYMQLSDKVNRKLLYAVS
SLICAIGFALPIGLPFKILWVALFNVFLFGFGHGMALWPQTRVWSTELFPTEIRNTAQGFVWGWMRIALGIWSIFVPSII
TVIGYSAIAAVATSFFILNIILGLLVGPDTHGKSLEVVIKDFYGGKVPVSKVVEVNTRPLGNK

Sequences:

>Translated_463_residues
MSEPSDPLKALDEAKLSSTHYRWTILSALADFLDAGAIVAGAASVSIWVSLFHLNSLLLGIIAALSPNAFAAGIGAWIAG
PLGDRYGRKAIYTYDLIVYAIGAIIILSAINYYMVIIGYTIVGLAVGVDVPTSWSLIAELAPKRNRGRLMSFTNLFWYIG
PIIILLLGIGTVPLGVNSFRVLFGFLTIVAIVTWVLRRGIAESARWGLVKGKEEVVKQALVQLGQSVSVIPKAETKGKWS
DMFKYWKGLAFMIPIYIFWGVPAGTFGFFLPFLIEDLSIKSSVVGDLVQIAWFVTAIIGVVGVYMQLSDKVNRKLLYAVS
SLICAIGFALPIGLPFKILWVALFNVFLFGFGHGMALWPQTRVWSTELFPTEIRNTAQGFVWGWMRIALGIWSIFVPSII
TVIGYSAIAAVATSFFILNIILGLLVGPDTHGKSLEVVIKDFYGGKVPVSKVVEVNTRPLGNK
>Mature_462_residues
SEPSDPLKALDEAKLSSTHYRWTILSALADFLDAGAIVAGAASVSIWVSLFHLNSLLLGIIAALSPNAFAAGIGAWIAGP
LGDRYGRKAIYTYDLIVYAIGAIIILSAINYYMVIIGYTIVGLAVGVDVPTSWSLIAELAPKRNRGRLMSFTNLFWYIGP
IIILLLGIGTVPLGVNSFRVLFGFLTIVAIVTWVLRRGIAESARWGLVKGKEEVVKQALVQLGQSVSVIPKAETKGKWSD
MFKYWKGLAFMIPIYIFWGVPAGTFGFFLPFLIEDLSIKSSVVGDLVQIAWFVTAIIGVVGVYMQLSDKVNRKLLYAVSS
LICAIGFALPIGLPFKILWVALFNVFLFGFGHGMALWPQTRVWSTELFPTEIRNTAQGFVWGWMRIALGIWSIFVPSIIT
VIGYSAIAAVATSFFILNIILGLLVGPDTHGKSLEVVIKDFYGGKVPVSKVVEVNTRPLGNK

Specific function: Minor myo-inositol uptake transporter [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786229, Length=442, Percent_Identity=22.8506787330317, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87082159, Length=452, Percent_Identity=21.6814159292035, Blast_Score=76, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24652793, Length=418, Percent_Identity=22.9665071770335, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24652795, Length=418, Percent_Identity=22.9665071770335, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 50504; Mature: 50372

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: PS50850 MFS ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHCCCCCCCCHHHHHHHHHCCCCCCHHHHHEECCCCCCCC
>Mature Secondary Structure 
SEPSDPLKALDEAKLSSTHYRWTILSALADFLDAGAIVAGAASVSIWVSLFHLNSLLLG
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
IIAALSPNAFAAGIGAWIAGPLGDRYGRKAIYTYDLIVYAIGAIIILSAINYYMVIIGYT
HHHHHCCCHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVGLAVGVDVPTSWSLIAELAPKRNRGRLMSFTNLFWYIGPIIILLLGIGTVPLGVNSFR
HHHHHHCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
VLFGFLTIVAIVTWVLRRGIAESARWGLVKGKEEVVKQALVQLGQSVSVIPKAETKGKWS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEECCCCCCCCCHH
DMFKYWKGLAFMIPIYIFWGVPAGTFGFFLPFLIEDLSIKSSVVGDLVQIAWFVTAIIGV
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGVYMQLSDKVNRKLLYAVSSLICAIGFALPIGLPFKILWVALFNVFLFGFGHGMALWPQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEECCC
TRVWSTELFPTEIRNTAQGFVWGWMRIALGIWSIFVPSIITVIGYSAIAAVATSFFILNI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILGLLVGPDTHGKSLEVVIKDFYGGKVPVSKVVEVNTRPLGNK
HHHHHCCCCCCCCHHHHHHHHHCCCCCCHHHHHEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7952181; 9384377; 1761221; 11807058 [H]