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The map label for this gene is hdrA [H]

Identifier: 15897989

GI number: 15897989

Start: 972029

End: 973135

Strand: Direct

Name: hdrA [H]

Synonym: SSO1131

Alternate gene names: 15897989

Gene position: 972029-973135 (Clockwise)

Preceding gene: 15897988

Following gene: 15897990

Centisome position: 32.48

GC content: 40.02

Gene sequence:

>1107_bases
GTGGCAAGTAAATCAGTCTTGGTTATAGGTGCTGGGCCAGCGGGTCTCTCAGCTACTAAGGAACTAGCGAATATGGGAGT
TAATGTTGTAGTTGTTGAGAGAGAACCGTTCTTAGGTGGTACGCCCAAGAGGTTAAAGTATAGTTTATTATTCCCCGAGC
TAAGACCAGCTTCTGAGGTTATCGATCCATTAGTAAAAACTGTCCAAGAGAACGGTAATGTTAAGATTTACACGGAAAGC
ATAGTTGATGCTGCTAAAAACACCTCTGACGGCTTTGAAATAAGTATTAAAGATAAGAATGGCAAAGTAAAGGTGGAGAA
AGCTAATGCAATAATTGCAGCTTCTGGTTTTGAGCACTTCGATTCTAGAAGGAAGTATGAATACGGTTATGGTATAATTC
CCAACATATACCAAATATCTGACATAGAGGGTATGCTTCACGAGAATAAGCTAGTTACCACAAAGGGAACTCCGCCTAAG
AGGGTTGCAATATTATTATGTGTAGGTTCTAGAGACGCTACTGTAGGAAATACTTATTGCTCAAGAGTATGTTGTGCTGT
GTCAATAAAGCAAGCTATGGAGATCAAACAGAGGATTCCAGATGCGGTAGTTCACATCTACTACATGGATATAAGAACTT
ATGGTCTAATGGAGGACAAATTATACTGGAAATCGCAACTAGATTACAGGGTTGGTTATATTAGAGGTAGAATTTCAGAG
TTCATGAGAGGTCCTAACGACACTGTCATAATAAAGGGAGAAGATACGATGAACTTGAATAGGGCGCTGACTGTGCCTTA
TGACATGGTAATATTGGCTAATGGAATGGAGCTTGGATTGGGTTCAAAACAAGTGGCTAAGATATTGGGATTGGAGTTTG
AAGAGCATGGTTTCGTTAAGCCGTTAGATCCAGATAGATTACCAGTCCAATCAACTAAGAAAGGAATATTCTTAGCTGGT
GCAATAACTGGGCCTAAGACTATTTCAGATTCCATAACTGAGGGATATGCAGCAGCAATGAAAGCTTATGAATATATCAC
GCATGGAATATGGGAAGAGTCGGATTTCGCAAAGAAAACTGCGGAGATGAAGGTGGTACATCATTAA

Upstream 100 bases:

>100_bases
TCCAGATAGAGTAAAATGGTACAAGAAGGAGGTTCCAAAGTAAATACAGTAAAAGCAAAGTTTTTTAAATTAAATTTACT
TAATAAAAGGTGGTGATTAA

Downstream 100 bases:

>100_bases
CATTTTTTTAAACATTGATTACGTAAGGGATATTTTTAACGCGATATTAGCTAAAGATGCAAATAATACTGCTAAGAGCA
ATCCTAAGGAATCATTATCA

Product: heterodisulfide reductase, subunit A (hdrA)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 367

Protein sequence:

>368_residues
MASKSVLVIGAGPAGLSATKELANMGVNVVVVEREPFLGGTPKRLKYSLLFPELRPASEVIDPLVKTVQENGNVKIYTES
IVDAAKNTSDGFEISIKDKNGKVKVEKANAIIAASGFEHFDSRRKYEYGYGIIPNIYQISDIEGMLHENKLVTTKGTPPK
RVAILLCVGSRDATVGNTYCSRVCCAVSIKQAMEIKQRIPDAVVHIYYMDIRTYGLMEDKLYWKSQLDYRVGYIRGRISE
FMRGPNDTVIIKGEDTMNLNRALTVPYDMVILANGMELGLGSKQVAKILGLEFEEHGFVKPLDPDRLPVQSTKKGIFLAG
AITGPKTISDSITEGYAAAMKAYEYITHGIWEESDFAKKTAEMKVVHH

Sequences:

>Translated_368_residues
MASKSVLVIGAGPAGLSATKELANMGVNVVVVEREPFLGGTPKRLKYSLLFPELRPASEVIDPLVKTVQENGNVKIYTES
IVDAAKNTSDGFEISIKDKNGKVKVEKANAIIAASGFEHFDSRRKYEYGYGIIPNIYQISDIEGMLHENKLVTTKGTPPK
RVAILLCVGSRDATVGNTYCSRVCCAVSIKQAMEIKQRIPDAVVHIYYMDIRTYGLMEDKLYWKSQLDYRVGYIRGRISE
FMRGPNDTVIIKGEDTMNLNRALTVPYDMVILANGMELGLGSKQVAKILGLEFEEHGFVKPLDPDRLPVQSTKKGIFLAG
AITGPKTISDSITEGYAAAMKAYEYITHGIWEESDFAKKTAEMKVVHH
>Mature_367_residues
ASKSVLVIGAGPAGLSATKELANMGVNVVVVEREPFLGGTPKRLKYSLLFPELRPASEVIDPLVKTVQENGNVKIYTESI
VDAAKNTSDGFEISIKDKNGKVKVEKANAIIAASGFEHFDSRRKYEYGYGIIPNIYQISDIEGMLHENKLVTTKGTPPKR
VAILLCVGSRDATVGNTYCSRVCCAVSIKQAMEIKQRIPDAVVHIYYMDIRTYGLMEDKLYWKSQLDYRVGYIRGRISEF
MRGPNDTVIIKGEDTMNLNRALTVPYDMVILANGMELGLGSKQVAKILGLEFEEHGFVKPLDPDRLPVQSTKKGIFLAGA
ITGPKTISDSITEGYAAAMKAYEYITHGIWEESDFAKKTAEMKVVHH

Specific function: Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). May act as the catalytic subunit [H]

COG id: COG1148

COG function: function code C; Heterodisulfide reductase, subunit A and related polyferredoxins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 4 4Fe-4S ferredoxin-type domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR003953
- InterPro:   IPR003813
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00890 FAD_binding_2; PF00037 Fer4; PF02662 FlpD [H]

EC number: =1.8.98.1 [H]

Molecular weight: Translated: 40666; Mature: 40534

Theoretical pI: Translated: 8.51; Mature: 8.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASKSVLVIGAGPAGLSATKELANMGVNVVVVEREPFLGGTPKRLKYSLLFPELRPASEV
CCCCCEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCCCCCHHHEEEEEECCCCCCHHHH
IDPLVKTVQENGNVKIYTESIVDAAKNTSDGFEISIKDKNGKVKVEKANAIIAASGFEHF
HHHHHHHHHCCCCEEEEEHHHHHHHCCCCCCEEEEEECCCCEEEEEECCEEEEECCCHHH
DSRRKYEYGYGIIPNIYQISDIEGMLHENKLVTTKGTPPKRVAILLCVGSRDATVGNTYC
HCCCCEECCCCCCCCCEEECCHHHHHCCCEEEEECCCCCCEEEEEEEECCCCCCCCHHHH
SRVCCAVSIKQAMEIKQRIPDAVVHIYYMDIRTYGLMEDKLYWKSQLDYRVGYIRGRISE
HHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCHHHHHHHHCCCEEHHHHHHHHHH
FMRGPNDTVIIKGEDTMNLNRALTVPYDMVILANGMELGLGSKQVAKILGLEFEEHGFVK
HHCCCCCEEEEECCCCCCCCEEEECCEEEEEEECCCEECCCHHHHHHHHCCCCCCCCCCC
PLDPDRLPVQSTKKGIFLAGAITGPKTISDSITEGYAAAMKAYEYITHGIWEESDFAKKT
CCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
AEMKVVHH
HCEEEECC
>Mature Secondary Structure 
ASKSVLVIGAGPAGLSATKELANMGVNVVVVEREPFLGGTPKRLKYSLLFPELRPASEV
CCCCEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCCCCCHHHEEEEEECCCCCCHHHH
IDPLVKTVQENGNVKIYTESIVDAAKNTSDGFEISIKDKNGKVKVEKANAIIAASGFEHF
HHHHHHHHHCCCCEEEEEHHHHHHHCCCCCCEEEEEECCCCEEEEEECCEEEEECCCHHH
DSRRKYEYGYGIIPNIYQISDIEGMLHENKLVTTKGTPPKRVAILLCVGSRDATVGNTYC
HCCCCEECCCCCCCCCEEECCHHHHHCCCEEEEECCCCCCEEEEEEEECCCCCCCCHHHH
SRVCCAVSIKQAMEIKQRIPDAVVHIYYMDIRTYGLMEDKLYWKSQLDYRVGYIRGRISE
HHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCHHHHHHHHCCCEEHHHHHHHHHH
FMRGPNDTVIIKGEDTMNLNRALTVPYDMVILANGMELGLGSKQVAKILGLEFEEHGFVK
HHCCCCCEEEEECCCCCCCCEEEECCEEEEEEECCCEECCCHHHHHHHHCCCCCCCCCCC
PLDPDRLPVQSTKKGIFLAGAITGPKTISDSITEGYAAAMKAYEYITHGIWEESDFAKKT
CCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
AEMKVVHH
HCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]