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The map label for this gene is argE-2 [H]

Identifier: 15897881

GI number: 15897881

Start: 863102

End: 864232

Strand: Direct

Name: argE-2 [H]

Synonym: SSO1007

Alternate gene names: 15897881

Gene position: 863102-864232 (Clockwise)

Preceding gene: 15897880

Following gene: 15897882

Centisome position: 28.84

GC content: 35.1

Gene sequence:

>1131_bases
ATGTTATATCCAGTAAAACTACTGAAAGACCTAGTACAAATCAAAACAGCAAATCCACCTGGGTCAGAATACGAGAGCAT
TTCGTTTTATCTGAAAGACCTATTTAACGATTTAGGTTTTCAAATACAACTAATCGAAATACCAGAGGAATATATGGATA
AATACTACATTTACTCTCCATCACACAAAGGAAACAAAAGAATAATAGTAATTGCCAAGAATAGTCCCAACCCTATACTC
CACTTCAACTTCCATTATGACGTCGTTCCACCAGGAGATGGTTGGTTAACAAACCCTTTCGAACTCAAGGTAGTCGATAA
TAAGGCGTACGGAAGAGGAACTTCAGATATGAAAGGTTCAATTGTGAGTTTATATTTAGCCCTATCTAGATTTAATGATT
TACCAATCGAGATAGTGTTTGTCCCAGACGAGGAAAGTGGAGGTATAGGGACTAAATACTTGACAGAGGAAATTCGTATC
GCTCCTAGTACTGCTATATTTGGTGAACCTAGTTTTCCTAACGTGTATATAGGGCATTTGGGTATAGTGAGGGGTATAAT
AAAAATATTTGGTAAACAAGCTCACGCAAGCAACCCAAAAGATGGCATTAATGCCTTTCTGCTAGCTTCTAAACTAGCAC
TAAAACTACAAGAAAAATTAGGAAATGAAATAGTTAACCTTGGGGGATATACGCTTAATCCCACTAATAATGATGGAATA
GTACCGGGTTTCTTTGCCTTTAGCTATTATAGAGCTATTCCTCCCCATGATAATAGAACCCCAGAATTTGACAAGAATGT
AATTGACACTACAGCTAGAGAAGTAGGAATAGAGTATAATTTTGAGATTAAATCTTTCATTTCAGGCTCAGTTTCTAATC
CAGATTCCAGTGTAGCTAAAGCGTTTAAGTTTTGTATCACTTCAACTCTTAACGTAGTACCTAAAGAACTAATAAGTAAT
ATAAGATATGACGCAGTCTTCTATAAAAATCTCGATTCGATAAACTTTGGCCCAGGAAGTTTAGATCAAGCTCATGTACC
TAATGAGTATGTTGAATTAGATAACATAGAGAAAACTATTGTGATTTATGAATGCGTGATGAAAAGGATTTATTTTAATA
ATTATCGATAA

Upstream 100 bases:

>100_bases
AAAATGGAGGGAAAGTGTATGAAGAGAAAGAATTAGAAGAATTAGAGAATAGATTAGGAAAATCAAGCTTGTTAAAAGCT
AAAAGAAGGTAATCATTGAA

Downstream 100 bases:

>100_bases
AAACCCTTAACTTTCTTAAAAATCTTCCAATTATTTCAGTAGTGTCTATCTTTTAATATGAAAAATTTTTGATGTTTTAG
TTTGAAAAATTTATTAAGTG

Product: succinyl-diaminopimelate desuccinylase

Products: NA

Alternate protein names: SDAP desuccinylase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase [H]

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MLYPVKLLKDLVQIKTANPPGSEYESISFYLKDLFNDLGFQIQLIEIPEEYMDKYYIYSPSHKGNKRIIVIAKNSPNPIL
HFNFHYDVVPPGDGWLTNPFELKVVDNKAYGRGTSDMKGSIVSLYLALSRFNDLPIEIVFVPDEESGGIGTKYLTEEIRI
APSTAIFGEPSFPNVYIGHLGIVRGIIKIFGKQAHASNPKDGINAFLLASKLALKLQEKLGNEIVNLGGYTLNPTNNDGI
VPGFFAFSYYRAIPPHDNRTPEFDKNVIDTTAREVGIEYNFEIKSFISGSVSNPDSSVAKAFKFCITSTLNVVPKELISN
IRYDAVFYKNLDSINFGPGSLDQAHVPNEYVELDNIEKTIVIYECVMKRIYFNNYR

Sequences:

>Translated_376_residues
MLYPVKLLKDLVQIKTANPPGSEYESISFYLKDLFNDLGFQIQLIEIPEEYMDKYYIYSPSHKGNKRIIVIAKNSPNPIL
HFNFHYDVVPPGDGWLTNPFELKVVDNKAYGRGTSDMKGSIVSLYLALSRFNDLPIEIVFVPDEESGGIGTKYLTEEIRI
APSTAIFGEPSFPNVYIGHLGIVRGIIKIFGKQAHASNPKDGINAFLLASKLALKLQEKLGNEIVNLGGYTLNPTNNDGI
VPGFFAFSYYRAIPPHDNRTPEFDKNVIDTTAREVGIEYNFEIKSFISGSVSNPDSSVAKAFKFCITSTLNVVPKELISN
IRYDAVFYKNLDSINFGPGSLDQAHVPNEYVELDNIEKTIVIYECVMKRIYFNNYR
>Mature_376_residues
MLYPVKLLKDLVQIKTANPPGSEYESISFYLKDLFNDLGFQIQLIEIPEEYMDKYYIYSPSHKGNKRIIVIAKNSPNPIL
HFNFHYDVVPPGDGWLTNPFELKVVDNKAYGRGTSDMKGSIVSLYLALSRFNDLPIEIVFVPDEESGGIGTKYLTEEIRI
APSTAIFGEPSFPNVYIGHLGIVRGIIKIFGKQAHASNPKDGINAFLLASKLALKLQEKLGNEIVNLGGYTLNPTNNDGI
VPGFFAFSYYRAIPPHDNRTPEFDKNVIDTTAREVGIEYNFEIKSFISGSVSNPDSSVAKAFKFCITSTLNVVPKELISN
IRYDAVFYKNLDSINFGPGSLDQAHVPNEYVELDNIEKTIVIYECVMKRIYFNNYR

Specific function: Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bact

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. DapE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=351, Percent_Identity=28.7749287749288, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1789236, Length=323, Percent_Identity=24.1486068111455, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR005941
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.18 [H]

Molecular weight: Translated: 42314; Mature: 42314

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYPVKLLKDLVQIKTANPPGSEYESISFYLKDLFNDLGFQIQLIEIPEEYMDKYYIYSP
CCCHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCHHHCCCEEEECC
SHKGNKRIIVIAKNSPNPILHFNFHYDVVPPGDGWLTNPFELKVVDNKAYGRGTSDMKGS
CCCCCCEEEEEECCCCCCEEEEEEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCHHHH
IVSLYLALSRFNDLPIEIVFVPDEESGGIGTKYLTEEIRIAPSTAIFGEPSFPNVYIGHL
HHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHEECCCEEECCCCCCCCEEHHHH
GIVRGIIKIFGKQAHASNPKDGINAFLLASKLALKLQEKLGNEIVNLGGYTLNPTNNDGI
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHCCCEEECCCCCCCC
VPGFFAFSYYRAIPPHDNRTPEFDKNVIDTTAREVGIEYNFEIKSFISGSVSNPDSSVAK
CCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCEECEEEHHHHCCCCCCCHHHHHH
AFKFCITSTLNVVPKELISNIRYDAVFYKNLDSINFGPGSLDQAHVPNEYVELDNIEKTI
HHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCHHEECCCCCHHH
VIYECVMKRIYFNNYR
HHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLYPVKLLKDLVQIKTANPPGSEYESISFYLKDLFNDLGFQIQLIEIPEEYMDKYYIYSP
CCCHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCHHHCCCEEEECC
SHKGNKRIIVIAKNSPNPILHFNFHYDVVPPGDGWLTNPFELKVVDNKAYGRGTSDMKGS
CCCCCCEEEEEECCCCCCEEEEEEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCHHHH
IVSLYLALSRFNDLPIEIVFVPDEESGGIGTKYLTEEIRIAPSTAIFGEPSFPNVYIGHL
HHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHEECCCEEECCCCCCCCEEHHHH
GIVRGIIKIFGKQAHASNPKDGINAFLLASKLALKLQEKLGNEIVNLGGYTLNPTNNDGI
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHCCCEEECCCCCCCC
VPGFFAFSYYRAIPPHDNRTPEFDKNVIDTTAREVGIEYNFEIKSFISGSVSNPDSSVAK
CCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCEECEEEHHHHCCCCCCCHHHHHH
AFKFCITSTLNVVPKELISNIRYDAVFYKNLDSINFGPGSLDQAHVPNEYVELDNIEKTI
HHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCHHEECCCCCHHH
VIYECVMKRIYFNNYR
HHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA